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Journal Articles

A TCR V alpha CDR3-specific motif associated with Lewis rat autoimmune encephalomyelitis and basic protein-specific T cell clones.

A C Buenafe, R C Tsu, B Bebo, Jr, A C Bakke, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1997) 158 (11): 5472–5483.
https://doi.org/10.4049/jimmunol.158.11.5472
Published: 01 June 1997
View article titled, A TCR V alpha CDR3-specific motif associated with Lewis rat autoimmune encephalomyelitis and basic protein-specific T cell clones.
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Journal Articles

Myelin antigen-coupled splenocytes suppress experimental autoimmune encephalomyelitis in Lewis rats through a partially reversible anergy mechanism.

A A Vandenbark, B Celnik, M Vainiene, S D Miller, H Offner
Journal: The Journal of Immunology
J Immunol (1995) 155 (12): 5861–5867.
https://doi.org/10.4049/jimmunol.155.12.5861
Published: 15 December 1995
View article titled, Myelin antigen-coupled splenocytes suppress experimental autoimmune encephalomyelitis in Lewis rats through a partially reversible anergy mechanism.
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Journal Articles

Analysis of V beta 8.2 CDR3 sequences from spinal cord T cells of Lewis rats vaccinated or treated with TCR V beta 8.2-39-59 peptide.

A C Buenafe, M Vainiene, B Celnik, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1995) 155 (3): 1556–1564.
https://doi.org/10.4049/jimmunol.155.3.1556
Published: 01 August 1995
View article titled, Analysis of V beta 8.2 CDR3 sequences from spinal cord T cells of Lewis rats vaccinated or treated with TCR V beta 8.2-39-59 peptide.
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Journal Articles

Increased severity of experimental autoimmune encephalomyelitis in rats tolerized as adults but not neonatally to a protective TCR V beta 8 CDR2 idiotope.

H Offner, M K Malotky, L Pope, M Vainiene, B Celnik, S D Miller, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1995) 154 (2): 928–935.
https://doi.org/10.4049/jimmunol.154.2.928
Published: 15 January 1995
View article titled, Increased severity of experimental autoimmune encephalomyelitis in rats tolerized as adults but not neonatally to a protective TCR V beta 8 CDR2 idiotope.
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Journal Articles

Coculture of TCR peptide-specific T cells with basic protein-specific T cells inhibits proliferation, IL-3 mRNA, and transfer of experimental autoimmune encephalomyelitis.

H Offner, M Vainiene, B Celnik, A D Weinberg, A Buenafe, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1994) 153 (11): 4988–4996.
https://doi.org/10.4049/jimmunol.153.11.4988
Published: 01 December 1994
View article titled, Coculture of TCR peptide-specific T cells with basic protein-specific T cells inhibits proliferation, IL-3 mRNA, and transfer of experimental autoimmune encephalomyelitis.
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Journal Articles

Definition of encephalitogenic and immunodominant epitopes of guinea pig myelin basic protein (Gp-BP) in Lewis rats tolerized neonatally with Gp-BP or Gp-BP peptides.

A A Vandenbark, M Vainiene, B Celnik, G A Hashim, A Buenafe, H Offner
Journal: The Journal of Immunology
J Immunol (1994) 153 (2): 852–861.
https://doi.org/10.4049/jimmunol.153.2.852
Published: 15 July 1994
View article titled, Definition of encephalitogenic and immunodominant epitopes of guinea pig myelin basic protein (Gp-BP) in Lewis rats tolerized neonatally with Gp-BP or Gp-BP peptides.
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Journal Articles

Immunity to TCR peptides in multiple sclerosis: II. T cell recognition of Vb5.2 and Vb6.1 CDR2 peptides

YK Chou, WJ Morrison, R Weinberg AD: Dedrick, R Whitham, DN Bourdette, G Hashim, H Offner, AA Vandenbark
Journal: The Journal of Immunology
J Immunol (1994) 153 (2): 910.
https://doi.org/10.4049/jimmunol.153.2.910.c
Published: 15 July 1994
View article titled, Immunity to TCR peptides in multiple sclerosis: II. T cell recognition of Vb5.2 and Vb6.1 CDR2 peptides
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Journal Articles

Immunity to TCR peptides in multiple sclerosis: I. Successful immunization of patients with synthetic Vb5.2 and Vb6.1 CDR2 peptides

DN Bourdette, RH Whitham, YK Chou, WJ Morrison, J Atherton, C Kenny, D Liefeld, GA Hashim, H Offner, AA Vandenbark
Journal: The Journal of Immunology
J Immunol (1994) 153 (2): 910.
https://doi.org/10.4049/jimmunol.153.2.910.b
Published: 15 July 1994
View article titled, Immunity to TCR peptides in multiple sclerosis: I. Successful immunization of patients with synthetic Vb5.2 and Vb6.1 CDR2 peptides
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Journal Articles

Analysis of V beta 8-CDR3 sequences derived from central nervous system of Lewis rats with experimental autoimmune encephalomyelitis.

A C Buenafe, M Vainiene, B Celnik, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1994) 153 (1): 386–394.
https://doi.org/10.4049/jimmunol.153.1.386
Published: 01 July 1994
View article titled, Analysis of V beta 8-CDR3 sequences derived from central nervous system of Lewis rats with experimental autoimmune encephalomyelitis.
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Journal Articles

Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis.

A D Weinberg, J J Wallin, R E Jones, T J Sullivan, D N Bourdette, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1994) 152 (9): 4712–4721.
https://doi.org/10.4049/jimmunol.152.9.4712
Published: 01 May 1994
View article titled, Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis.
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Journal Articles

Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides.

D N Bourdette, R H Whitham, Y K Chou, W J Morrison, J Atherton, C Kenny, D Liefeld, G A Hashim, H Offner, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1994) 152 (5): 2510–2519.
https://doi.org/10.4049/jimmunol.152.5.2510
Published: 01 March 1994
View article titled, Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides.
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Journal Articles

Immunity to TCR peptides in multiple sclerosis. II. T cell recognition of V beta 5.2 and V beta 6.1 CDR2 peptides.

Y K Chou, W J Morrison, A D Weinberg, R Dedrick, R Whitham, D N Bourdette, G Hashim, H Offner, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1994) 152 (5): 2520–2529.
https://doi.org/10.4049/jimmunol.152.5.2520
Published: 01 March 1994
View article titled, Immunity to TCR peptides in multiple sclerosis. II. T cell recognition of V beta 5.2 and V beta 6.1 CDR2 peptides.
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Journal Articles

Where, when, and how to detect biased expression of disease-relevant V beta genes in rats with experimental autoimmune encephalomyelitis.

H Offner, A C Buenafe, M Vainiene, B Celnik, A D Weinberg, D P Gold, G Hashim, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1993) 151 (1): 506–517.
https://doi.org/10.4049/jimmunol.151.1.506
Published: 01 July 1993
View article titled, Where, when, and how to detect biased expression of disease-relevant V beta genes in rats with experimental autoimmune encephalomyelitis.
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Journal Articles

Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells.

R E Jones, D N Bourdette, R H Whitham, H Offner, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1993) 150 (10): 4620–4629.
https://doi.org/10.4049/jimmunol.150.10.4620
Published: 15 May 1993
View article titled, Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells.
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Journal Articles

Spontaneous development of protective anti-T cell receptor autoimmunity targeted against a natural EAE-regulatory idiotope located within the 39-59 region of the TCR-V beta 8.2 chain.

G A Hashim, H Offner, R Y Wang, K Shukla, E Carvalho, W J Morrison, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1992) 149 (8): 2803–2809.
https://doi.org/10.4049/jimmunol.149.8.2803
Published: 15 October 1992
View article titled, Spontaneous development of protective anti-T cell receptor autoimmunity targeted against a natural EAE-regulatory idiotope located within the 39-59 region of the TCR-V beta 8.2 chain.
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Journal Articles

Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis.

A D Weinberg, R Whitham, S L Swain, W J Morrison, G Wyrick, C Hoy, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1992) 148 (7): 2109–2117.
https://doi.org/10.4049/jimmunol.148.7.2109
Published: 01 April 1992
View article titled, Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis.
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Journal Articles

Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. II. Biased T cell receptor V beta expression predominates in spinal cord infiltrating T cells.

D P Gold, M Vainiene, B Celnik, S Wiley, C Gibbs, G A Hashim, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1992) 148 (6): 1712–1717.
https://doi.org/10.4049/jimmunol.148.6.1712
Published: 15 March 1992
View article titled, Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. II. Biased T cell receptor V beta expression predominates in spinal cord infiltrating T cells.
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Journal Articles

Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. I. T cell receptor peptide regulation of T cell clones expressing cross-reactive V beta genes.

H Offner, M Vainiene, D P Gold, B Celnik, R Wang, G A Hashim, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1992) 148 (6): 1706–1711.
https://doi.org/10.4049/jimmunol.148.6.1706
Published: 15 March 1992
View article titled, Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. I. T cell receptor peptide regulation of T cell clones expressing cross-reactive V beta genes.
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Journal Articles

Location of a new encephalitogenic epitope (residues 43 to 64) in proteolipid protein that induces relapsing experimental autoimmune encephalomyelitis in PL/J and (SJL x PL)F1 mice.

R H Whitham, R E Jones, G A Hashim, C M Hoy, R Y Wang, A A Vandenbark, H Offner
Journal: The Journal of Immunology
J Immunol (1991) 147 (11): 3803–3808.
https://doi.org/10.4049/jimmunol.147.11.3803
Published: 01 December 1991
View article titled, Location of a new encephalitogenic epitope (residues 43 to 64) in proteolipid protein that induces relapsing experimental autoimmune encephalomyelitis in PL/J and (SJL x PL)F1 mice.
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Protection against experimental encephalomyelitis. Idiotypic autoregulation induced by a nonencephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene.

H Offner, M Vainiene, D P Gold, W J Morrison, R Y Wang, G A Hashim, A A Vandenbark
Journal: The Journal of Immunology
J Immunol (1991) 146 (12): 4165–4172.
https://doi.org/10.4049/jimmunol.146.12.4165
Published: 15 June 1991
View article titled, Protection against experimental encephalomyelitis. Idiotypic autoregulation induced by a nonencephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene.
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