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Journal Articles

Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells.

A C Jaleco, B Blom, P Res, K Weijer, L L Lanier, J H Phillips, H Spits
Journal: The Journal of Immunology
J Immunol (1997) 159 (2): 694–702.
https://doi.org/10.4049/jimmunol.159.2.694
Published: 15 July 1997
View articletitled, Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells.
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Journal Articles

Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage.

B Blom, P Res, E Noteboom, K Weijer, H Spits
Journal: The Journal of Immunology
J Immunol (1997) 158 (8): 3571–3577.
https://doi.org/10.4049/jimmunol.158.8.3571
Published: 15 April 1997
View articletitled, Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage.
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Journal Articles

CD40 expressed on thymic epithelial cells provides costimulation for proliferation but not for apoptosis of human thymocytes.

G Ruggiero, E Martinez Cáceres, A Voordouw, E Noteboom, D Graf, R A Kroczek, H Spits
Journal: The Journal of Immunology
J Immunol (1996) 156 (10): 3737–3746.
https://doi.org/10.4049/jimmunol.156.10.3737
Published: 15 May 1996
View articletitled, CD40 expressed on thymic epithelial cells provides costimulation for proliferation but not for apoptosis of human thymocytes.
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Journal Articles

In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells.

B A Vandekerckhove, A Bárcena, D Schols, S Mohan-Peterson, H Spits, M G Roncarolo
Journal: The Journal of Immunology
J Immunol (1994) 152 (4): 1738–1743.
https://doi.org/10.4049/jimmunol.152.4.1738
Published: 15 February 1994
View articletitled, In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells.
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Journal Articles

Identification of human pre-T/NK cell-associated genes.

M G Ranes-Goldberg, T Hori, S Mohan-Peterson, H Spits
Journal: The Journal of Immunology
J Immunol (1993) 151 (10): 5810–5821.
https://doi.org/10.4049/jimmunol.151.10.5810
Published: 15 November 1993
View articletitled, Identification of human pre-T/NK cell-associated genes.
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Journal Articles

Analysis of cytokine production by Mycobacterium-reactive T cells. Failure to explain Mycobacterium leprae-specific nonresponsiveness of peripheral blood T cells from lepromatous leprosy patients.

T Mutis, E M Kraakman, Y E Cornelisse, J B Haanen, H Spits, R R De Vries, T H Ottenhoff
Journal: The Journal of Immunology
J Immunol (1993) 150 (10): 4641–4651.
https://doi.org/10.4049/jimmunol.150.10.4641
Published: 15 May 1993
View articletitled, Analysis of cytokine production by Mycobacterium-reactive T cells. Failure to explain Mycobacterium leprae-specific nonresponsiveness of peripheral blood T cells from lepromatous leprosy patients.
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Journal Articles

IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.

H Yssel, R De Waal Malefyt, M G Roncarolo, J S Abrams, R Lahesmaa, H Spits, J E de Vries
Journal: The Journal of Immunology
J Immunol (1992) 149 (7): 2378–2384.
https://doi.org/10.4049/jimmunol.149.7.2378
Published: 01 October 1992
View articletitled, IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.
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Journal Articles

Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes.

L L Lanier, C Chang, H Spits, J H Phillips
Journal: The Journal of Immunology
J Immunol (1992) 149 (6): 1876–1880.
https://doi.org/10.4049/jimmunol.149.6.1876
Published: 15 September 1992
View articletitled, Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes.
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Journal Articles

CD40 is functionally expressed on human thymic epithelial cells.

A H Galy, H Spits
Journal: The Journal of Immunology
J Immunol (1992) 149 (3): 775–782.
https://doi.org/10.4049/jimmunol.149.3.775
Published: 01 August 1992
View articletitled, CD40 is functionally expressed on human thymic epithelial cells.
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Journal Articles

IL-1, IL-4, and IFN-gamma differentially regulate cytokine production and cell surface molecule expression in cultured human thymic epithelial cells.

A H Galy, H Spits
Journal: The Journal of Immunology
J Immunol (1991) 147 (11): 3823–3830.
https://doi.org/10.4049/jimmunol.147.11.3823
Published: 01 December 1991
View articletitled, IL-1, IL-4, and IFN-gamma differentially regulate cytokine production and cell surface molecule expression in cultured human thymic epithelial cells.
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Journal Articles

Functional and phenotypic differences between CD4+ and CD4- T cell receptor-gamma delta clones from peripheral blood.

H Spits, X Paliard, Y Vandekerckhove, P van Vlasselaer, J E de Vries
Journal: The Journal of Immunology
J Immunol (1991) 147 (4): 1180–1188.
https://doi.org/10.4049/jimmunol.147.4.1180
Published: 15 August 1991
View articletitled, Functional and phenotypic differences between CD4+ and CD4- T cell receptor-gamma delta clones from peripheral blood.
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Journal Articles

Natural killer cell clones can efficiently process and present protein antigens.

M G Roncarolo, M Bigler, J B Haanen, H Yssel, R Bacchetta, J E de Vries, H Spits
Journal: The Journal of Immunology
J Immunol (1991) 147 (3): 781–787.
https://doi.org/10.4049/jimmunol.147.3.781
Published: 01 August 1991
View articletitled, Natural killer cell clones can efficiently process and present protein antigens.
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Journal Articles

Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse.

B A Vandekerckhove, J F Krowka, J M McCune, J E de Vries, H Spits, M G Roncarolo
Journal: The Journal of Immunology
J Immunol (1991) 146 (12): 4173–4179.
https://doi.org/10.4049/jimmunol.146.12.4173
Published: 15 June 1991
View articletitled, Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse.
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Journal Articles

Identification of a novel human thymocyte subset with a phenotype of CD3- CD4+ CD8 alpha + beta-1. Possible progeny of the CD3- CD4- CD8- subset.

T Hori, J Cupp, N Wrighton, F Lee, H Spits
Journal: The Journal of Immunology
J Immunol (1991) 146 (12): 4078–4084.
https://doi.org/10.4049/jimmunol.146.12.4078
Published: 15 June 1991
View articletitled, Identification of a novel human thymocyte subset with a phenotype of CD3- CD4+ CD8 alpha + beta-1. Possible progeny of the CD3- CD4- CD8- subset.
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Journal Articles

Clonal analysis of human CD4-CD8-CD3- thymocytes highly purified from postnatal thymus.

T Hori, H Spits
Journal: The Journal of Immunology
J Immunol (1991) 146 (7): 2116–2121.
https://doi.org/10.4049/jimmunol.146.7.2116
Published: 01 April 1991
View articletitled, Clonal analysis of human CD4-CD8-CD3- thymocytes highly purified from postnatal thymus.
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Journal Articles

Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria.

J B Haanen, T H Ottenhoff, R F Lai A Fat, H Soebono, H Spits, R R de Vries
Journal: The Journal of Immunology
J Immunol (1990) 145 (11): 3898–3904.
https://doi.org/10.4049/jimmunol.145.11.3898
Published: 01 December 1990
View articletitled, Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria.
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Journal Articles

Human T cell leukemia virus type I prevents cell surface expression of the T cell receptor through down-regulation of the CD3-gamma, -delta, -epsilon, and -zeta genes.

R de Waal Malefyt, H Yssel, H Spits, J E de Vries, J Sancho, C Terhorst, B Alarcon
Journal: The Journal of Immunology
J Immunol (1990) 145 (7): 2297–2303.
https://doi.org/10.4049/jimmunol.145.7.2297
Published: 01 October 1990
View articletitled, Human T cell leukemia virus type I prevents cell surface expression of the T cell receptor through down-regulation of the CD3-gamma, -delta, -epsilon, and -zeta genes.
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Journal Articles

Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156.

H Spits, X Paliard, V H Engelhard, J E de Vries
Journal: The Journal of Immunology
J Immunol (1990) 144 (11): 4156–4162.
https://doi.org/10.4049/jimmunol.144.11.4156
Published: 01 June 1990
View articletitled, Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156.
Open the PDF for Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156. in another window
Add to Citation Manager for Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156.
Journal Articles

Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4.

R Bacchetta, R de Waal Malefijt, H Yssel, J Abrams, J E de Vries, H Spits, M G Roncarolo
Journal: The Journal of Immunology
J Immunol (1990) 144 (3): 902–908.
https://doi.org/10.4049/jimmunol.144.3.902
Published: 01 February 1990
View articletitled, Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4.
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Journal Articles

IL-4 induces LFA-1 and LFA-3 expression on Burkitt's lymphoma cell lines. Requirement of additional activation by phorbol myristate acetate for induction of homotypic cell adhesions.

F Rousset, M Billaud, D Blanchard, C Figdor, G M Lenoir, H Spits, J E De Vries
Journal: The Journal of Immunology
J Immunol (1989) 143 (5): 1490–1498.
https://doi.org/10.4049/jimmunol.143.5.1490
Published: 01 September 1989
View articletitled, IL-4 induces LFA-1 and LFA-3 expression on Burkitt's lymphoma cell lines. Requirement of additional activation by phorbol myristate acetate for induction of homotypic cell adhesions.
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