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Habib Zaghouani
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Journal Articles

Towards optimizing cancer immunotherapeutic index: anti-CD3 Mono-Fab, a novel T cell-based therapeutic approach with less auto-Immunogenic profile.

Onyekachi Okpasuo, Chandrashekara Mahadevappa, Hien Huynh, Christa Cheatam, Vijay Radhakrishnan, Habib Zaghouani, Craig Franklin, Adam Schrum, Diana Gil
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 1099_5317.
https://doi.org/10.4049/jimmunol.212.supp.1099.5317
Published: 01 May 2024
View articletitled, Towards optimizing cancer immunotherapeutic index: anti-CD3 Mono-Fab, a novel T cell-based therapeutic approach with less auto-Immunogenic profile.
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Journal Articles

Evaluating potential toxicities of cancer immunotherapies using autoimmune animal models.

Onyekachi Juliet Okpasuo, Alexis N Cattin-Roy, Natalia Karasseva, Chandrashekara Puthanapura Mahadevappa, Vijay Radhakrishnan, Habib Zaghouani, Diana Gil Pages
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 122.19.
https://doi.org/10.4049/jimmunol.208.Supp.122.19
Published: 01 May 2022
View articletitled, Evaluating potential toxicities of cancer immunotherapies using autoimmune animal models.
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Journal Articles

Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity

Subhasis Barik, Alexis N. Cattin-Roy, Tobechukwu K. Ukah, Mindy M. Miller, Emma Teixeiro, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2020) 205 (8): 2039–2045.
https://doi.org/10.4049/jimmunol.2000614
Published: 15 October 2020
View articletitled, Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity
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Includes: Supplementary data
Journal Articles

A New IRF-1–Driven Apoptotic Pathway Triggered by IL-4/IL-13 Kills Neonatal Th1 Cells and Weakens Protection against Viral Infection

Mindy M. Miller, Subhasis Barik, Alexis N. Cattin-Roy, Tobechukwu K. Ukah, Christine M. Hoeman, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2019) 202 (11): 3173–3186.
https://doi.org/10.4049/jimmunol.1800943
Published: 01 June 2019
View articletitled, A New IRF-1–Driven Apoptotic Pathway Triggered by IL-4/IL-13 Kills Neonatal Th1 Cells and Weakens Protection against Viral Infection
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Includes: Supplementary data
Journal Articles

Type II Cytokines in the Thymic Microenvironment Influence T cell Negative Selection in Type One Diabetes

Alexis N Cattin-Roy, Tobechukwu Kenneth Ukah, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 181.1.
https://doi.org/10.4049/jimmunol.202.Supp.181.1
Published: 01 May 2019
View articletitled, Type II Cytokines in the Thymic Microenvironment Influence T cell Negative Selection in Type One Diabetes
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Journal Articles

IL-4 and IL-13 Guide Early Thymic Progenitors To Mature toward Dendritic Cells

Subhasis Barik, Alexis N. Cattin-Roy, Mindy M. Miller, Tobechukwu K. Ukah, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2018) 201 (10): 2947–2958.
https://doi.org/10.4049/jimmunol.1701186
Published: 15 November 2018
View articletitled, IL-4 and IL-13 Guide Early Thymic Progenitors To Mature toward Dendritic Cells
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Includes: Supplementary data
Journal Articles

Immune Modulation and Vascular Repair Sustain Pancreatic Beta Cell Regeneration To Reverse Late Stage Type 1 Diabetes

Tobechukwu Kenneth Ukah, Alexis N. Cattin-Roy, Mindy M. Miller, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 176.8.
https://doi.org/10.4049/jimmunol.200.Supp.176.8
Published: 01 May 2018
View articletitled, Immune Modulation and Vascular Repair Sustain Pancreatic Beta Cell Regeneration To Reverse Late Stage Type 1 Diabetes
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Journal Articles

Type II Cytokines Guide Early Thymic Progenitor Lineage Choice and Influence Negative Selection of Myelin-Reactive T cells

Alexis N. Cattin-Roy, Subhasis Barik, Mindy M. Miller, Tobechukwu Kenneth Ukah, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 165.10.
https://doi.org/10.4049/jimmunol.200.Supp.165.10
Published: 01 May 2018
View articletitled, Type II Cytokines Guide Early Thymic Progenitor Lineage Choice and Influence Negative Selection of Myelin-Reactive T cells
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Journal Articles

IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage

Subhasis Barik, Mindy M. Miller, Alexis N. Cattin-Roy, Tobechukwu K. Ukah, Weirong Chen, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2017) 199 (8): 2767–2776.
https://doi.org/10.4049/jimmunol.1700498
Published: 15 October 2017
View articletitled, IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage
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Includes: Supplementary data
Journal Articles

IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis

Subhasis Barik, Jason S. Ellis, Jason A. Cascio, Mindy M. Miller, Tobechukwu K. Ukah, Alexis N. Cattin-Roy, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2017) 199 (7): 2236–2248.
https://doi.org/10.4049/jimmunol.1700372
Published: 01 October 2017
View articletitled, IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis
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Journal Articles

On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes

Tobechukwu K. Ukah, Alexis N. Cattin-Roy, Weirong Chen, Mindy M. Miller, Subhasis Barik, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2017) 199 (3): 894–902.
https://doi.org/10.4049/jimmunol.1700410
Published: 01 August 2017
View articletitled, On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Antigen-Specific Immune Modulation Targets mTORC1 Function To Drive Chemokine Receptor–Mediated T Cell Tolerance

Weirong Chen, Xiaoxiao Wan, Tobechukwu K. Ukah, Mindy M. Miller, Subhasis Barik, Alexis N. Cattin-Roy, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2016) 197 (9): 3554–3565.
https://doi.org/10.4049/jimmunol.1601032
Published: 01 November 2016
View articletitled, Antigen-Specific Immune Modulation Targets mTORC1 Function To Drive Chemokine Receptor–Mediated T Cell Tolerance
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Includes: Supplementary data
Journal Articles

Group 2 innate lymphoid cells collaborate with dendritic cells to potentiate memory Th2 cell responses.

Timotheus You Fu Halim, You Yi Hwang, Seth Scanlon, Natalio Garbi, Habib Zaghouani, Padraic G Fallon, Andrew McKenzie
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 68.2.
https://doi.org/10.4049/jimmunol.196.Supp.68.2
Published: 01 May 2016
View articletitled, Group 2 innate lymphoid cells collaborate with dendritic cells to potentiate memory Th2 cell responses.
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Journal Articles

PI3K-AKT-mTOR pathway mediates trafficking of diabetogenic T cells by modulating CXCR3 via T-bet

Weirong Chen, Tobechukwu Kenneth Ukah, Mindy M Miller, Habib Zaghouani, Xiaoxiao Wan
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 57.1.
https://doi.org/10.4049/jimmunol.196.Supp.57.1
Published: 01 May 2016
View articletitled, PI3K-AKT-mTOR pathway mediates trafficking of diabetogenic T cells by modulating CXCR3 via T-bet
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Journal Articles

Neonatal Basophils Stifle the Function of Early-Life Dendritic Cells To Curtail Th1 Immunity in Newborn Mice

Mermagya Dhakal, Mindy M. Miller, Adam A. Zaghouani, Michael P. Sherman, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2015) 195 (2): 507–518.
https://doi.org/10.4049/jimmunol.1500027
Published: 15 July 2015
View articletitled, Neonatal Basophils Stifle the Function of Early-Life Dendritic Cells To Curtail Th1 Immunity in Newborn Mice
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Includes: Supplementary data
Journal Articles

Basophils’ IL-4 stifles the function of neonatal DCs and promotes Th2 immunity in newborn mice (CCR4P.212)

Mindy Miller, Mermagya Dhakal, Subhasis Barik, Weirong Chen, Tobechukwu Ukah, Jason Ellis, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 118.12.
https://doi.org/10.4049/jimmunol.194.Supp.118.12
Published: 01 May 2015
View articletitled, Basophils’ IL-4 stifles the function of neonatal DCs and promotes Th2 immunity in newborn mice (CCR4P.212)
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Journal Articles

Mechanisms underlying cytokine receptor suppression of type 1 diabetes (BA11P.127)

Tobechukwu Ukah, Weirong Chen, Mindy Miller, Subhasis Barik, Jason Ellis, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 184.9.
https://doi.org/10.4049/jimmunol.194.Supp.184.9
Published: 01 May 2015
View articletitled, Mechanisms underlying cytokine receptor suppression of type 1 diabetes (BA11P.127)
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Journal Articles

Molecular mechanism underlying immune modulation during stem cell therapy of overt type 1 diabetes (THER5P.917)

Weirong Chen, Tobechukwu Ukah, Mindy Miller, Jason Ellis, Subhasis Barik, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 139.19.
https://doi.org/10.4049/jimmunol.194.Supp.139.19
Published: 01 May 2015
View articletitled, Molecular mechanism underlying immune modulation during stem cell therapy of overt type 1 diabetes (THER5P.917)
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Journal Articles

IL-13Rα1 plays a role in CD4+ T cell stimulation by antigen presenting cells and affects CNS autoimmunity (BA14P.213)

Marie-Therese Khairallah, Jason Ellis, Weirong Chen, Mindy Miller, Tobechukwu Ukah, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 178.14.
https://doi.org/10.4049/jimmunol.192.Supp.178.14
Published: 01 May 2014
View articletitled, IL-13Rα1 plays a role in CD4+ T cell stimulation by antigen presenting cells and affects CNS autoimmunity (BA14P.213)
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Journal Articles

IL-13 heteroreceptor and Th1 cells: the race for control of neonatal immunity (CCR5P.256)

Mindy Miller, Mermagya Dhakal, Weirong Chen, Jason Ellis, Marie-Therese Khairallah, Tobechukwu Ukah, Habib Zaghouani
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 181.10.
https://doi.org/10.4049/jimmunol.192.Supp.181.10
Published: 01 May 2014
View articletitled, IL-13 heteroreceptor and Th1 cells: the race for control of neonatal immunity (CCR5P.256)
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