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Journal Articles

Circulating classical monocytes share a common transcriptional signature with skin macrophages in Systemic Sclerosis

Hadijat M Makinde, Salina T Dominguez, Carla M Cuda, Gaurav Gadhvi, Kathleen Aren, Chang Zeng, Garrett J Eickelberg, Dinesh Khanna, Shervin Assassi, Tracy Frech, Deborah R Winter, Harris Perlman, Monique Hinchcliff
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 152.12.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.152.12
Published: 01 May 2020
View article titled, Circulating classical monocytes share a common transcriptional signature with skin macrophages in Systemic Sclerosis
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Journal Articles

Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1

Kathryn A. Radigan, Trevor T. Nicholson, Lynn C. Welch, Monica Chi, Luciano Amarelle, Martín Angulo, Masahiko Shigemura, Atsuko Shigemura, Constance E. Runyan, Luisa Morales-Nebreda, Harris Perlman, Ermelinda Ceco, Emilia Lecuona, Laura A. Dada, Alexander V. Misharin, Gokhan M. Mutlu, Jacob I. Sznajder, G. R. Scott Budinger
Journal: The Journal of Immunology
J Immunol (2019) 202 (2): 484–493.
DOI: https://doi.org/10.4049/jimmunol.1701433
Published: 15 January 2019
View article titled, Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1
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Journal Articles

Neuropsychiatric lupus is lipocalin-2 dependent

Elise V. Mike, Carla Cuda, Hadijat Makinde, Harris Perlman, Chaim Putterman
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 100.18.
DOI: https://doi.org/10.4049/jimmunol.200.Supp.100.18
Published: 01 May 2018
View article titled, Neuropsychiatric lupus is lipocalin-2 dependent
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Journal Articles

Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice

Bria M. Coates, Kelly L. Staricha, Clarissa M. Koch, Yuan Cheng, Dale K. Shumaker, G. R. Scott Budinger, Harris Perlman, Alexander V. Misharin, Karen M. Ridge
Journal: The Journal of Immunology
J Immunol (2018) 200 (7): 2391–2404.
DOI: https://doi.org/10.4049/jimmunol.1701543
Published: 01 April 2018
View article titled, Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice
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Includes: Supplementary data
Journal Articles

Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity

Stephen Chiu, Ramiro Fernandez, Vijay Subramanian, Haiying Sun, Malcolm M. DeCamp, Daniel Kreisel, Harris Perlman, G. R. Scott Budinger, Thalachallour Mohanakumar, Ankit Bharat
Journal: The Journal of Immunology
J Immunol (2016) 197 (1): 51–57.
DOI: https://doi.org/10.4049/jimmunol.1502539
Published: 01 July 2016
View article titled, Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity
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Journal Articles

Temporal expression of Bim limits the development and repertoire of TCR+ double negative thymocytes and CD8αα intestinal intraepithelial lymphocytes.

Kun-Po Li, Anke Fähnrich, Eron Roy, Carla Cuda, H Leighton Grimes, Harris Perlman, Kathrin Kalies, David A Hildeman
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 121.9.
DOI: https://doi.org/10.4049/jimmunol.196.Supp.121.9
Published: 01 May 2016
View article titled, Temporal expression of Bim limits the development and repertoire of TCR<sup>+</sup> double negative thymocytes and CD8αα intestinal intraepithelial lymphocytes.
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Journal Articles

Bim expression in early DP thymocytes limits development of TCRαβ+DN thymocytes and CD8αα intestinal intraepithelial lymphocytes (HEM2P.243)

Kun-Po Li, Eron Roy, Carla Cuda, H Grimes, Harris Perlman, David Hildeman
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 51.13.
DOI: https://doi.org/10.4049/jimmunol.194.Supp.51.13
Published: 01 May 2015
View article titled, Bim expression in early DP thymocytes limits development of TCRαβ<sup>+</sup>DN thymocytes and CD8αα intestinal intraepithelial lymphocytes (HEM2P.243)
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Journal Articles

Caspase-8 Acts as a Molecular Rheostat To Limit RIPK1- and MyD88-Mediated Dendritic Cell Activation

Carla M. Cuda, Alexander V. Misharin, Angelica K. Gierut, Rana Saber, G. Kenneth Haines, III, Jack Hutcheson, Stephen M. Hedrick, Chandra Mohan, G. Scott Budinger, Christian Stehlik, Harris Perlman
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5548–5560.
DOI: https://doi.org/10.4049/jimmunol.1400122
Published: 15 June 2014
View article titled, Caspase-8 Acts as a Molecular Rheostat To Limit RIPK1- and MyD88-Mediated Dendritic Cell Activation
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Includes: Supplementary data
Journal Articles

POP3 is a novel inhibitor of ALR inflammasomes and controls host defense to DNA virus infections (INM6P.411)

Christian Stehlik, Sonal Khare, Rojo Ratsimandresy, Lúcia de Almeida, Carla Cuda, Stephanie Rellick, Alexander Misharin, Melissa Wallin, Anu Gangopadhyay, Eleonora Forte, Eva Gottwein, Harris Perlman, John Reed, David Greaves, Andrea Dorfleutner
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 122.8.
DOI: https://doi.org/10.4049/jimmunol.192.Supp.122.8
Published: 01 May 2014
View article titled, POP3 is a novel inhibitor of ALR inflammasomes and controls host defense to DNA virus infections (INM6P.411)
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Journal Articles

Simvastatin Treatment Ameliorates Autoimmune Disease Associated with Accelerated Atherosclerosis in a Murine Lupus Model

Tamar Aprahamian, Ramon Bonegio, Jennifer Rizzo, Harris Perlman, David J. Lefer, Ian R. Rifkin, Kenneth Walsh
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 3028–3034.
DOI: https://doi.org/10.4049/jimmunol.177.5.3028
Published: 01 September 2006
View article titled, Simvastatin Treatment Ameliorates Autoimmune Disease Associated with Accelerated Atherosclerosis in a Murine Lupus Model
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Journal Articles

Mcl-1 Is Essential for the Survival of Synovial Fibroblasts in Rheumatoid Arthritis

Hongtao Liu, Polikseni Eksarko, Vladislav Temkin, G. Kenneth Haines, III, Harris Perlman, Alisa E. Koch, Bayar Thimmapaya, Richard M. Pope
Journal: The Journal of Immunology
J Immunol (2005) 175 (12): 8337–8345.
DOI: https://doi.org/10.4049/jimmunol.175.12.8337
Published: 15 December 2005
View article titled, Mcl-1 Is Essential for the Survival of Synovial Fibroblasts in Rheumatoid Arthritis
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Journal Articles

Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo.

Nathaniel J. Brown, Jack Hutcheson, Emily Bickel, John C. Scatizzi, Lee D. Albee, G. Kenneth Haines, III, Joy Eslick, Kathleen Bradley, Elsa Taricone, Harris Perlman
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3818.
DOI: https://doi.org/10.4049/jimmunol.174.6.3818-b
Published: 15 March 2005
View article titled, Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo.
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Journal Articles

Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo

Nathaniel J. Brown, Jack Hutcheson, Emily Bickel, John C. Scatizzi, Lee D. Albee, G. Kenneth Haines, III, Joy Eslick, Kathleen Bradley, Elsa Taricone, Harris Perlman
Journal: The Journal of Immunology
J Immunol (2004) 173 (12): 7584–7593.
DOI: https://doi.org/10.4049/jimmunol.173.12.7584
Published: 15 December 2004
View article titled, Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo
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Journal Articles

TNF-α-Induced Apoptosis of Macrophages Following Inhibition of NF-κB: A Central Role for Disruption of Mitochondria

Hongtao Liu, Yingyu Ma, Lisa J. Pagliari, Harris Perlman, Chenfei Yu, Anning Lin, Richard M. Pope
Journal: The Journal of Immunology
J Immunol (2004) 172 (3): 1907–1915.
DOI: https://doi.org/10.4049/jimmunol.172.3.1907
Published: 01 February 2004
View article titled, TNF-α-Induced Apoptosis of Macrophages Following Inhibition of NF-κB: A Central Role for Disruption of Mitochondria
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Journal Articles

Regulation of Cyclooxygenase-2 Expression by Macrophages in Response to Double-Stranded RNA and Viral Infection

Sarah A. Steer, Jason M. Moran, Leonard B. Maggi, Jr., R. Mark L. Buller, Harris Perlman, John A. Corbett
Journal: The Journal of Immunology
J Immunol (2003) 170 (2): 1070–1076.
DOI: https://doi.org/10.4049/jimmunol.170.2.1070
Published: 15 January 2003
View article titled, Regulation of Cyclooxygenase-2 Expression by Macrophages in Response to Double-Stranded RNA and Viral Infection
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Journal Articles

IL-6 and Matrix Metalloproteinase-1 Are Regulated by the Cyclin-Dependent Kinase Inhibitor p21 in Synovial Fibroblasts

Harris Perlman, Kathleen Bradley, Hongtao Liu, Shawn Cole, Eli Shamiyeh, Roy C. Smith, Kenneth Walsh, Stefano Fiore, Alisa E. Koch, Gary S. Firestein, G. Kenneth Haines, III, Richard M. Pope
Journal: The Journal of Immunology
J Immunol (2003) 170 (2): 838–845.
DOI: https://doi.org/10.4049/jimmunol.170.2.838
Published: 15 January 2003
View article titled, IL-6 and Matrix Metalloproteinase-1 Are Regulated by the Cyclin-Dependent Kinase Inhibitor p21 in Synovial Fibroblasts
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Journal Articles

Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-κB But Not C/EBPβ or c-Jun

Constantinos Georganas, Hongtao Liu, Harris Perlman, Alexander Hoffmann, Bayar Thimmapaya, Richard M. Pope
Journal: The Journal of Immunology
J Immunol (2000) 165 (12): 7199–7206.
DOI: https://doi.org/10.4049/jimmunol.165.12.7199
Published: 15 December 2000
View article titled, Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-κB But Not C/EBPβ or c-Jun
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Journal Articles

Bcl-2 Expression in Synovial Fibroblasts Is Essential for Maintaining Mitochondrial Homeostasis and Cell Viability

Harris Perlman, Constantinos Georganas, Lisa J. Pagliari, Alisa E. Koch, Kenneth Haines, III, Richard M. Pope
Journal: The Journal of Immunology
J Immunol (2000) 164 (10): 5227–5235.
DOI: https://doi.org/10.4049/jimmunol.164.10.5227
Published: 15 May 2000
View article titled, Bcl-2 Expression in Synovial Fibroblasts Is Essential for Maintaining Mitochondrial Homeostasis and Cell Viability
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