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Helen E. Thomas
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Journal Articles

Altering β Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice

David J. De George, Gaurang Jhala, Claudia Selck, Prerak Trivedi, Thomas C. Brodnicki, Leanne Mackin, Thomas W. Kay, Helen E. Thomas, Balasubramanian Krishnamurthy
Journal: The Journal of Immunology
J Immunol (2024) 212 (11): 1658–1669.
https://doi.org/10.4049/jimmunol.2300785
Published: 08 April 2024
View article titled, Altering β Cell Antigen Exposure to Exhausted CD8<sup>+</sup> T Cells Prevents Autoimmune Diabetes in Mice
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Includes: Supplementary data
Journal Articles

Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes

Jonathan Chee, Hyun-Ja Ko, Ania Skowera, Gaurang Jhala, Tara Catterall, Kate L. Graham, Robyn M. Sutherland, Helen E. Thomas, Andrew M. Lew, Mark Peakman, Thomas W. H. Kay, Balasubramanian Krishnamurthy
Journal: The Journal of Immunology
J Immunol (2014) 192 (2): 572–580.
https://doi.org/10.4049/jimmunol.1302100
Published: 15 January 2014
View article titled, Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

TNF Receptor 1 Deficiency Increases Regulatory T Cell Function in Nonobese Diabetic Mice

Jonathan Chee, Eveline Angstetra, Lina Mariana, Kate L. Graham, Emma M. Carrington, Horst Bluethmann, Pere Santamaria, Janette Allison, Thomas W. H. Kay, Balasubramanian Krishnamurthy, Helen E. Thomas
Journal: The Journal of Immunology
J Immunol (2011) 187 (4): 1702–1712.
https://doi.org/10.4049/jimmunol.1100511
Published: 15 August 2011
View article titled, TNF Receptor 1 Deficiency Increases Regulatory T Cell Function in Nonobese Diabetic Mice
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Includes: Supplementary data
Journal Articles

Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice

Balasubramanian Krishnamurthy, Lina Mariana, Shane A. Gellert, Peter G. Colman, Leonard C. Harrison, Andrew M. Lew, Pere Santamaria, Helen E. Thomas, Thomas W. H. Kay
Journal: The Journal of Immunology
J Immunol (2008) 180 (7): 4458–4464.
https://doi.org/10.4049/jimmunol.180.7.4458
Published: 01 April 2008
View article titled, Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice
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Journal Articles

IL-1β Breaks Tolerance through Expansion of CD25+ Effector T Cells

Brendan J. O’Sullivan, Helen E. Thomas, Saparna Pai, Pere Santamaria, Yoichiro Iwakura, Raymond J. Steptoe, Thomas W. H. Kay, Ranjeny Thomas
Journal: The Journal of Immunology
J Immunol (2006) 176 (12): 7278–7287.
https://doi.org/10.4049/jimmunol.176.12.7278
Published: 15 June 2006
View article titled, IL-1β Breaks Tolerance through Expansion of CD25<sup>+</sup> Effector T Cells
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Journal Articles

Transgenic Expression of Dominant-Negative Fas-Associated Death Domain Protein in β Cells Protects against Fas Ligand-Induced Apoptosis and Reduces Spontaneous Diabetes in Nonobese Diabetic Mice

Janette Allison, Helen E. Thomas, Tara Catterall, Thomas W. H. Kay, Andreas Strasser
Journal: The Journal of Immunology
J Immunol (2005) 175 (1): 293–301.
https://doi.org/10.4049/jimmunol.175.1.293
Published: 01 July 2005
View article titled, Transgenic Expression of Dominant-Negative Fas-Associated Death Domain Protein in β Cells Protects against Fas Ligand-Induced Apoptosis and Reduces Spontaneous Diabetes in Nonobese Diabetic Mice
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Journal Articles

Suppressor of Cytokine Signaling-1 Overexpression Protects Pancreatic β Cells from CD8+ T Cell-Mediated Autoimmune Destruction

Mark M. W. Chong, Ye Chen, Rima Darwiche, Nadine L. Dudek, Windy Irawaty, Pere Santamaria, Janette Allison, Thomas W. H. Kay, Helen E. Thomas
Journal: The Journal of Immunology
J Immunol (2004) 172 (9): 5714–5721.
https://doi.org/10.4049/jimmunol.172.9.5714
Published: 01 May 2004
View article titled, Suppressor of Cytokine Signaling-1 Overexpression Protects Pancreatic β Cells from CD8<sup>+</sup> T Cell-Mediated Autoimmune Destruction
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Journal Articles

Fas Is Detectable on β Cells in Accelerated, But Not Spontaneous, Diabetes in Nonobese Diabetic Mice

Rima Darwiche, Mark M. W. Chong, Pere Santamaria, Helen E. Thomas, Thomas W. H. Kay
Journal: The Journal of Immunology
J Immunol (2003) 170 (12): 6292–6297.
https://doi.org/10.4049/jimmunol.170.12.6292
Published: 15 June 2003
View article titled, Fas Is Detectable on β Cells in Accelerated, But Not Spontaneous, Diabetes in Nonobese Diabetic Mice
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Journal Articles

Evidence That β Cell Death in the Nonobese Diabetic Mouse Is Fas Independent

Helen E. Thomas, Rima Darwiche, John A. Corbett, Thomas W. H. Kay
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1562–1569.
https://doi.org/10.4049/jimmunol.163.3.1562
Published: 01 August 1999
View article titled, Evidence That β Cell Death in the Nonobese Diabetic Mouse Is Fas Independent
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