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Hideo Yagita
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Journal Articles

Anti-CD11b antibody treatment suppresses the disease conditions in rheumatoid arthritis (RA)-prone, FcγRIIB-deficient mice

Kazuko Takahashi, Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 183.16.
https://doi.org/10.4049/jimmunol.202.Supp.183.16
Published: 01 May 2019
View article titled, Anti-CD11b antibody treatment suppresses the disease conditions in rheumatoid arthritis (RA)-prone, FcγRIIB-deficient mice
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Journal Articles

Integrin β1 Promotes the Interaction of Murine IgG3 with Effector Cells

Carolyn Saylor Hawk, Carolina Coelho, Diane Sthefany Lima de Oliveira, Verenice Paredes, Patrícia Albuquerque, Anamélia Lorenzetti Bocca, Ananésia Correa dos Santos, Victoria Rusakova, Heather Holemon, Ildinete Silva-Pereira, Maria Sueli Soares Felipe, Hideo Yagita, André Moraes Nicola, Arturo Casadevall
Journal: The Journal of Immunology
J Immunol (2019) 202 (9): 2782–2794.
https://doi.org/10.4049/jimmunol.1701795
Published: 01 May 2019
View article titled, Integrin β1 Promotes the Interaction of Murine IgG3 with Effector Cells
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Includes: Supplementary data
Journal Articles

Role of the CD27/CD70 pathway in regulatory T cell function

Natalia Bowakim, Valérie Acolty, Maxime Dhainaut, Hideo Yagita, Guillaume Oldenhove, Oberdan Leo, Muriel Moser
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 47.27.
https://doi.org/10.4049/jimmunol.200.Supp.47.27
Published: 01 May 2018
View article titled, Role of the CD27/CD70 pathway in regulatory T cell function
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Journal Articles

Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity

Maher G. Nawaf, Maria H. Ulvmar, David R. Withers, Fiona M. McConnell, Fabrina M. Gaspal, Gwilym J. Webb, Nick D. Jones, Hideo Yagita, James P. Allison, Peter J. L. Lane
Journal: The Journal of Immunology
J Immunol (2017) 199 (3): 974–981.
https://doi.org/10.4049/jimmunol.1700088
Published: 01 August 2017
View article titled, Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity
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Includes: Supplementary data
Journal Articles

Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation

Jeffrey J. Teoh, Awndre E. Gamache, Alyssa L. Gillespie, Michael D. Stadnisky, Hideo Yagita, Timothy N. J. Bullock, Michael G. Brown
Journal: The Journal of Immunology
J Immunol (2016) 197 (11): 4360–4370.
https://doi.org/10.4049/jimmunol.1601049
Published: 01 December 2016
View article titled, Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8<sup>+</sup> T Cell Dependence on CD27 Costimulation
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Includes: Supplementary data
Journal Articles

Dual Blockade of OX40 and CD30 Signaling Reduces Memory Th2-driven Lung Inflammatory Responses to House Dust Mite Allergen

Donald Tom Gracias, Amit Kumar Mehta, Hideo Yagita, Michael Croft
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 192.2.
https://doi.org/10.4049/jimmunol.196.Supp.192.2
Published: 01 May 2016
View article titled, Dual Blockade of OX40 and CD30 Signaling Reduces Memory Th2-driven Lung Inflammatory Responses to House Dust Mite Allergen
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Journal Articles

The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation

Lijun Meng, Zhenjiang Bai, Shan He, Kazuhiro Mochizuki, Yongnian Liu, Janaki Purushe, Hongxing Sun, Jian Wang, Hideo Yagita, Shin Mineishi, Henry Fung, Gregory A. Yanik, Roberto Caricchio, Xiaoxuan Fan, Lisa M. Crisalli, Elizabeth O. Hexner, Ran Reshef, Yanyun Zhang, Yi Zhang
Journal: The Journal of Immunology
J Immunol (2016) 196 (3): 1070–1080.
https://doi.org/10.4049/jimmunol.1501310
Published: 01 February 2016
View article titled, The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation
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Includes: Supplementary data
Journal Articles

FasL-expressing B cells are major players in type 1 diabetes (BA6P.129)

Ankit Saxena, Zuoxiang Xiao, Hideo Yagita, Ben Larman, Thomas Donner, Abdel Rahim Hamad
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 114.10.
https://doi.org/10.4049/jimmunol.194.Supp.114.10
Published: 01 May 2015
View article titled, FasL-expressing B cells are major players in type 1 diabetes (BA6P.129)
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Journal Articles

Type I interferons promote lupus through disruption of the lymphotoxin receptor-mediated mechanosensing MKL1 pathway in marginal zone macrophages (BA4P.124)

John Mountz, Hao Li, Hui-Chen Hsu, Yong Zhou, Qi Wu, PingAr Yang, Jun Li, Bao Luo, Laurence Morel, Carl Ware, Yang Fu, Hideo Yagita
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 47.4.
https://doi.org/10.4049/jimmunol.194.Supp.47.4
Published: 01 May 2015
View article titled, Type I interferons promote lupus through disruption of the lymphotoxin receptor-mediated mechanosensing MKL1 pathway in marginal zone macrophages (BA4P.124)
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Journal Articles

Tumour necrosis factor-related apoptosis inducing ligand promotes the development of experimental chronic obstructive pulmonary disease (MUC1P.905)

Philip Hansbro, Tatt Haw, Prema Nair, Irwan Hanish, Duc Nguyen, Gang Liu, Mark Inman, Richard Kim, Adam Collison, Darryl Knight, Hideo Yagita, Joerg Mattes, Jay Horvat, Malcolm Starkey
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 64.6.
https://doi.org/10.4049/jimmunol.194.Supp.64.6
Published: 01 May 2015
View article titled, Tumour necrosis factor-related apoptosis inducing ligand promotes the development of experimental chronic obstructive pulmonary disease (MUC1P.905)
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Journal Articles

Notch Signaling Enhances FcεRI-Mediated Cytokine Production by Mast Cells through Direct and Indirect Mechanisms

Nobuhiro Nakano, Chiharu Nishiyama, Hideo Yagita, Mutsuko Hara, Yasutaka Motomura, Masato Kubo, Ko Okumura, Hideoki Ogawa
Journal: The Journal of Immunology
J Immunol (2015) 194 (9): 4535–4544.
https://doi.org/10.4049/jimmunol.1301850
Published: 01 May 2015
View article titled, Notch Signaling Enhances FcεRI-Mediated Cytokine Production by Mast Cells through Direct and Indirect Mechanisms
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Includes: Supplementary data
Journal Articles

PD-1 Suppresses Protective Immunity to Streptococcus pneumoniae through a B Cell–Intrinsic Mechanism

Jerome T. McKay, Ryan P. Egan, Rama D. Yammani, Lieping Chen, Tahiro Shin, Hideo Yagita, Karen M. Haas
Journal: The Journal of Immunology
J Immunol (2015) 194 (5): 2289–2299.
https://doi.org/10.4049/jimmunol.1401673
Published: 01 March 2015
View article titled, PD-1 Suppresses Protective Immunity to <em>Streptococcus pneumoniae</em> through a B Cell–Intrinsic Mechanism
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Includes: Supplementary data
Journal Articles

A Method for Detecting Intracellular Perforin in Mouse Lymphocytes

Amelia J. Brennan, Imran G. House, Jane Oliaro, Kelly M. Ramsbottom, Magdalena Hagn, Hideo Yagita, Joseph A. Trapani, Ilia Voskoboinik
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5744–5750.
https://doi.org/10.4049/jimmunol.1402207
Published: 01 December 2014
View article titled, A Method for Detecting Intracellular Perforin in Mouse Lymphocytes
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Includes: Multimedia, Supplementary data
Journal Articles

Inflammation and Lymphopenia Trigger Autoimmunity by Suppression of IL-2–Controlled Regulatory T Cell and Increase of IL-21–Mediated Effector T Cell Expansion

Nina Chevalier, Alison N. Thorburn, Laurence Macia, Jian Tan, Laurent Juglair, Hideo Yagita, Di Yu, Philip M. Hansbro, Charles R. Mackay
Journal: The Journal of Immunology
J Immunol (2014) 193 (10): 4845–4858.
https://doi.org/10.4049/jimmunol.1302966
Published: 15 November 2014
View article titled, Inflammation and Lymphopenia Trigger Autoimmunity by Suppression of IL-2–Controlled Regulatory T Cell and Increase of IL-21–Mediated Effector T Cell Expansion
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Includes: Supplementary data
Journal Articles

Programmed Death-1 Pathway in Host Tissues Ameliorates Th17/Th1-Mediated Experimental Chronic Graft-versus-Host Disease

Hideaki Fujiwara, Yoshinobu Maeda, Koichiro Kobayashi, Hisakazu Nishimori, Ken-ichi Matsuoka, Nobuharu Fujii, Eisei Kondo, Takehiro Tanaka, Lieping Chen, Miyuki Azuma, Hideo Yagita, Mitsune Tanimoto
Journal: The Journal of Immunology
J Immunol (2014) 193 (5): 2565–2573.
https://doi.org/10.4049/jimmunol.1400954
Published: 01 September 2014
View article titled, Programmed Death-1 Pathway in Host Tissues Ameliorates Th17/Th1-Mediated Experimental Chronic Graft-versus-Host Disease
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Includes: Supplementary data
Journal Articles

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

Jonathan M. Weiss, Jeff J. Subleski, Tim Back, Xin Chen, Stephanie K. Watkins, Hideo Yagita, Thomas J. Sayers, William J. Murphy, Robert H. Wiltrout
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5821–5829.
https://doi.org/10.4049/jimmunol.1400404
Published: 15 June 2014
View article titled, Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy
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Includes: Supplementary data
Journal Articles

ER stress response regulates the fate of myeloid-derived suppressor cells through TRAIL receptors mediated apoptosis (TUM4P.907)

Thomas Condamine, Vinit Kumar, Indu Ramachandran, Je-In Youn, Esteban Celis, Niklas Finnberg, Wafik El-Deiry, Rafael Winograd, Robert Vonderheide, Nickolas English, Stella Knight, Hideo Yagita, Judith Mccaffrey, Scott Antonia, Neil Hockstein, Robert Witt, Gregory Masters, Thomas Bauer, Dmitry Gabrilovich
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 138.8.
https://doi.org/10.4049/jimmunol.192.Supp.138.8
Published: 01 May 2014
View article titled, ER stress response regulates the fate of myeloid-derived suppressor cells through TRAIL receptors mediated apoptosis (TUM4P.907)
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Journal Articles

TNF receptor superfamily costimulation couples TCR signal strength to thymic Treg differentiation (BA13P.128)

Michael Farrar, Shawn Mahmud, Luke Manlove, Heather Schmitz, Yan Xing, Yanyan Wang, David Owen, Jason Schenkel, Jonathan Boomer, Jonathan Green, Hideo Yagita, Hongbo Chi, Kristin Hogquist
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 177.14.
https://doi.org/10.4049/jimmunol.192.Supp.177.14
Published: 01 May 2014
View article titled, TNF receptor superfamily costimulation couples TCR signal strength to thymic Treg differentiation (BA13P.128)
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Journal Articles

TIM-4 Has Dual Function in the Induction and Effector Phases of Murine Arthritis

Yoshiyuki Abe, Fumitaka Kamachi, Toshio Kawamoto, Fumihiko Makino, Jun Ito, Yuko Kojima, Alaa El Din Hussein Moustapha, Yoshihiko Usui, Hideo Yagita, Yoshinari Takasaki, Ko Okumura, Hisaya Akiba
Journal: The Journal of Immunology
J Immunol (2013) 191 (9): 4562–4572.
https://doi.org/10.4049/jimmunol.1203035
Published: 01 November 2013
View article titled, TIM-4 Has Dual Function in the Induction and Effector Phases of Murine Arthritis
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Includes: Supplementary data
Journal Articles

Interruption of the OX40–OX40 Ligand Pathway in LDL Receptor–Deficient Mice Causes Regression of Atherosclerosis

Amanda C. Foks, Gijs H. M. van Puijvelde, Ilze Bot, Mariette N. D. ter Borg, Kim L. L. Habets, Jason L. Johnson, Hideo Yagita, Theo J. C. van Berkel, Johan Kuiper
Journal: The Journal of Immunology
J Immunol (2013) 191 (9): 4573–4580.
https://doi.org/10.4049/jimmunol.1200708
Published: 01 November 2013
View article titled, Interruption of the OX40–OX40 Ligand Pathway in LDL Receptor–Deficient Mice Causes Regression of Atherosclerosis
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Includes: Supplementary data