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Journal Articles

Mucosal Mast Cell–Specific Gene Expression Is Promoted by Interdependent Action of Notch and TGF-β Signaling

Nobuhiro Nakano, Kazuki Saida, Mutsuko Hara, Kumi Izawa, Tomoaki Ando, Ayako Kaitani, Kazumi Kasakura, Takuya Yashiro, Chiharu Nishiyama, Hideoki Ogawa, Jiro Kitaura, Ko Okumura

J Immunol (2021) 207 (12): 3098–3106.

https://doi.org/10.4049/jimmunol.2100112

Published: 15 December 2021

View article titled, Mucosal Mast Cell–Specific Gene Expression Is Promoted by Interdependent Action of Notch and TGF-β Signaling

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Includes: Supplementary data

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The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells

Masanori Nagaoka, Takuya Yashiro, Yuna Uchida, Tomoaki Ando, Mutsuko Hara, Hajime Arai, Hideoki Ogawa, Ko Okumura, Kazumi Kasakura, Chiharu Nishiyama

J Immunol (2017) 199 (8): 2958–2967.

https://doi.org/10.4049/jimmunol.1601911

Published: 15 October 2017

View article titled, The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells

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Includes: Supplementary data

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Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes

Seiji Kamijo, Mayu Suzuki, Mutsuko Hara, Sakiko Shimura, Hirono Ochi, Natsuko Maruyama, Akira Matsuda, Hirohisa Saito, Susumu Nakae, Hajime Suto, Saori Ichikawa, Shigaku Ikeda, Hideoki Ogawa, Ko Okumura, Toshiro Takai

J Immunol (2016) 196 (9): 3559–3569.

https://doi.org/10.4049/jimmunol.1500717

Published: 01 May 2016

View article titled, Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes

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Includes: Supplementary data

Journal Articles

The Transcription Factor Ehf Is Involved in TGF-β–Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells

Susumu Yamazaki, Nobuhiro Nakano, Asuka Honjo, Mutsuko Hara, Keiko Maeda, Chiharu Nishiyama, Jiro Kitaura, Yoshikazu Ohtsuka, Ko Okumura, Hideoki Ogawa, Toshiaki Shimizu

J Immunol (2015) 195 (7): 3427–3435.

https://doi.org/10.4049/jimmunol.1402856

Published: 01 October 2015

View article titled, The Transcription Factor Ehf Is Involved in TGF-β–Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells

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Includes: Supplementary data

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Notch Signaling Enhances FcεRI-Mediated Cytokine Production by Mast Cells through Direct and Indirect Mechanisms

Nobuhiro Nakano, Chiharu Nishiyama, Hideo Yagita, Mutsuko Hara, Yasutaka Motomura, Masato Kubo, Ko Okumura, Hideoki Ogawa

J Immunol (2015) 194 (9): 4535–4544.

https://doi.org/10.4049/jimmunol.1301850

Published: 01 May 2015

View article titled, Notch Signaling Enhances FcεRI-Mediated Cytokine Production by Mast Cells through Direct and Indirect Mechanisms

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Includes: Supplementary data

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Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2

Eisuke Inage, Kazumi Kasakura, Takuya Yashiro, Ryuyo Suzuki, Yosuke Baba, Nobuhiro Nakano, Mutsuko Hara, Atsushi Tanabe, Keisuke Oboki, Kenji Matsumoto, Hirohisa Saito, François Niyonsaba, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu, Chiharu Nishiyama

J Immunol (2014) 192 (8): 3936–3946.

https://doi.org/10.4049/jimmunol.1302366

Published: 15 April 2014

View article titled, Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2

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Includes: Supplementary data

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IL-33–Mediated Innate Response and Adaptive Immune Cells Contribute to Maximum Responses of Protease Allergen–Induced Allergic Airway Inflammation

Seiji Kamijo, Haruna Takeda, Tomoko Tokura, Mayu Suzuki, Kyoko Inui, Mutsuko Hara, Hironori Matsuda, Akira Matsuda, Keisuke Oboki, Tatsukuni Ohno, Hirohisa Saito, Susumu Nakae, Katsuko Sudo, Hajime Suto, Saori Ichikawa, Hideoki Ogawa, Ko Okumura, Toshiro Takai

J Immunol (2013) 190 (9): 4489–4499.

https://doi.org/10.4049/jimmunol.1201212

Published: 01 May 2013

View article titled, IL-33–Mediated Innate Response and Adaptive Immune Cells Contribute to Maximum Responses of Protease Allergen–Induced Allergic Airway Inflammation

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Includes: Supplementary data

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The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis

Katsunari Kina, Hiromi Masuda, Hitoshi Nakayama, Yasuko Nagatsuka, Takuji Nabetani, Yoshio Hirabayashi, Yasue Takahashi, Kazunori Shimada, Hiroyuki Daida, Hideoki Ogawa, Kenji Takamori, Kazuhisa Iwabuchi

J Immunol (2011) 186 (9): 5323–5332.

https://doi.org/10.4049/jimmunol.1002100

Published: 01 May 2011

View article titled, The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis

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Includes: Supplementary data

Journal Articles

GATA2 and Sp1 Positively Regulate the c-kit Promoter in Mast Cells

Keiko Maeda, Chiharu Nishiyama, Hideoki Ogawa, Ko Okumura

J Immunol (2010) 185 (7): 4252–4260.

https://doi.org/10.4049/jimmunol.1001228

Published: 01 October 2010

View article titled, GATA2 and Sp1 Positively Regulate the c-kit Promoter in Mast Cells

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Journal Articles

Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

François Niyonsaba, Hiroko Ushio, Mutsuko Hara, Hidenori Yokoi, Mitsutoshi Tominaga, Kenji Takamori, Naoki Kajiwara, Hirohisa Saito, Isao Nagaoka, Hideoki Ogawa, Ko Okumura

J Immunol (2010) 184 (7): 3526–3534.

https://doi.org/10.4049/jimmunol.0900712

Published: 01 April 2010

View article titled, Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

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Journal Articles

Modulation of Allergenicity of Major House Dust Mite Allergens Der f 1 and Der p 1 by Interaction with an Endogenous Ligand

Toshiro Takai, Takeshi Kato, Hideki Hatanaka, Kyoko Inui, Takuya Nakazawa, Saori Ichikawa, Kouichi Mitsuishi, Hideoki Ogawa, Ko Okumura

J Immunol (2009) 183 (12): 7958–7965.

https://doi.org/10.4049/jimmunol.0713276

Published: 15 December 2009

View article titled, Modulation of Allergenicity of Major House Dust Mite Allergens Der f 1 and Der p 1 by Interaction with an Endogenous Ligand

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Journal Articles

Cupressaceae Pollen Grains Modulate Dendritic Cell Response and Exhibit IgE-Inducing Adjuvant Activity In Vivo

Seiji Kamijo, Toshiro Takai, Takatoshi Kuhara, Tomoko Tokura, Hiroko Ushio, Mikiko Ota, Norihiro Harada, Hideoki Ogawa, Ko Okumura

J Immunol (2009) 183 (10): 6087–6094.

https://doi.org/10.4049/jimmunol.0901039

Published: 15 November 2009

View article titled, Cupressaceae Pollen Grains Modulate Dendritic Cell Response and Exhibit IgE-Inducing Adjuvant Activity In Vivo

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Includes: Supplementary data

Journal Articles

A Subcytotoxic Dose of Subtilase Cytotoxin Prevents Lipopolysaccharide-Induced Inflammatory Responses, Depending on its Capacity to Induce the Unfolded Protein Response

Daisuke Harama, Kensuke Koyama, Mai Mukai, Naomi Shimokawa, Masanori Miyata, Yuki Nakamura, Yuko Ohnuma, Hideoki Ogawa, Shuji Matsuoka, Adrienne W. Paton, James C. Paton, Masanori Kitamura, Atsuhito Nakao

J Immunol (2009) 183 (2): 1368–1374.

https://doi.org/10.4049/jimmunol.0804066

Published: 15 July 2009

View article titled, A Subcytotoxic Dose of Subtilase Cytotoxin Prevents Lipopolysaccharide-Induced Inflammatory Responses, Depending on its Capacity to Induce the Unfolded Protein Response

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Journal Articles

Two Different Transcription Factors Discriminate the −315C>T Polymorphism of the FcεRIα Gene: Binding of Sp1 to −315C and of a High Mobility Group-Related Molecule to −315T

Shunsuke Kanada, Nobuhiro Nakano, Daniel P. Potaczek, Keiko Maeda, Naomi Shimokawa, Yusuke Niwa, Tatsuo Fukai, Marek Sanak, Andrew Szczeklik, Hideo Yagita, Ko Okumura, Hideoki Ogawa, Chiharu Nishiyama

J Immunol (2008) 180 (12): 8204–8210.

https://doi.org/10.4049/jimmunol.180.12.8204

Published: 15 June 2008

View article titled, Two Different Transcription Factors Discriminate the −315C>T Polymorphism of the FcεRIα Gene: Binding of Sp1 to −315C and of a High Mobility Group-Related Molecule to −315T

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Journal Articles

Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses

Yuko Kikuchi, Toshiro Takai, Takatoshi Kuhara, Mikiko Ota, Takeshi Kato, Hideki Hatanaka, Saori Ichikawa, Tomoko Tokura, Hisaya Akiba, Kouichi Mitsuishi, Shigaku Ikeda, Ko Okumura, Hideoki Ogawa

J Immunol (2006) 177 (3): 1609–1617.

https://doi.org/10.4049/jimmunol.177.3.1609

Published: 01 August 2006

View article titled, Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses

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Journal Articles

The Human β-Defensins (-1, -2, -3, -4) and Cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK Activation in Primary Human Keratinocytes

François Niyonsaba, Hiroko Ushio, Isao Nagaoka, Ko Okumura, Hideoki Ogawa

J Immunol (2005) 175 (3): 1776–1784.

https://doi.org/10.4049/jimmunol.175.3.1776

Published: 01 August 2005

View article titled, The Human β-Defensins (-1, -2, -3, -4) and Cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK Activation in Primary Human Keratinocytes

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Journal Articles

Smad3 Deficiency in Mast Cells Provides Efficient Host Protection against Acute Septic Peritonitis

Yutaka Kanamaru, Koji Sumiyoshi, Hiroko Ushio, Hideoki Ogawa, Ko Okumura, Atsuhito Nakao

J Immunol (2005) 174 (7): 4193–4197.

https://doi.org/10.4049/jimmunol.174.7.4193

Published: 01 April 2005

View article titled, Smad3 Deficiency in Mast Cells Provides Efficient Host Protection against Acute Septic Peritonitis

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Journal Articles

Mast Cells Acquire Monocyte-Specific Gene Expression and Monocyte-Like Morphology by Overproduction of PU.1

Tomonobu Ito, Chiharu Nishiyama, Makoto Nishiyama, Hironori Matsuda, Keiko Maeda, Yushiro Akizawa, Ryoji Tsuboi, Ko Okumura, Hideoki Ogawa

J Immunol (2005) 174 (1): 376–383.

https://doi.org/10.4049/jimmunol.174.1.376

Published: 01 January 2005

View article titled, Mast Cells Acquire Monocyte-Specific Gene Expression and Monocyte-Like Morphology by Overproduction of PU.1

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Journal Articles

Polymorphisms in the FcεRIβ Promoter Region Affecting Transcription Activity: A Possible Promoter-Dependent Mechanism for Association between FcεRIβ and Atopy

Chiharu Nishiyama, Yushiro Akizawa, Makoto Nishiyama, Tomoko Tokura, Hiroshi Kawada, Kouichi Mitsuishi, Masanari Hasegawa, Tomonobu Ito, Nobuhiro Nakano, Atsushi Okamoto, Atsushi Takagi, Hideo Yagita, Ko Okumura, Hideoki Ogawa

J Immunol (2004) 173 (10): 6458–6464.

https://doi.org/10.4049/jimmunol.173.10.6458

Published: 15 November 2004

View article titled, Polymorphisms in the FcεRIβ Promoter Region Affecting Transcription Activity: A Possible Promoter-Dependent Mechanism for Association between FcεRIβ and Atopy

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Journal Articles

A Novel −66T/C Polymorphism in FcεRI α-Chain Promoter Affecting the Transcription Activity: Possible Relationship to Allergic Diseases

Masanari Hasegawa, Chiharu Nishiyama, Makoto Nishiyama, Yushiro Akizawa, Kouichi Mitsuishi, Tomonobu Ito, Hiroshi Kawada, Susumu Furukawa, Chisei Ra, Ko Okumura, Hideoki Ogawa

J Immunol (2003) 171 (4): 1927–1933.

https://doi.org/10.4049/jimmunol.171.4.1927

Published: 15 August 2003

View article titled, A Novel −66T/C Polymorphism in FcεRI α-Chain Promoter Affecting the Transcription Activity: Possible Relationship to Allergic Diseases

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NARROW

Mucosal Mast Cell–Specific Gene Expression Is Promoted by Interdependent Action of Notch and TGF-β Signaling

The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells

Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes

The Transcription Factor Ehf Is Involved in TGF-β–Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells

Notch Signaling Enhances FcεRI-Mediated Cytokine Production by Mast Cells through Direct and Indirect Mechanisms

Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2

IL-33–Mediated Innate Response and Adaptive Immune Cells Contribute to Maximum Responses of Protease Allergen–Induced Allergic Airway Inflammation

The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis

GATA2 and Sp1 Positively Regulate the c-kit Promoter in Mast Cells

Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

Modulation of Allergenicity of Major House Dust Mite Allergens Der f 1 and Der p 1 by Interaction with an Endogenous Ligand

Cupressaceae Pollen Grains Modulate Dendritic Cell Response and Exhibit IgE-Inducing Adjuvant Activity In Vivo

A Subcytotoxic Dose of Subtilase Cytotoxin Prevents Lipopolysaccharide-Induced Inflammatory Responses, Depending on its Capacity to Induce the Unfolded Protein Response

Two Different Transcription Factors Discriminate the −315C>T Polymorphism of the FcεRIα Gene: Binding of Sp1 to −315C and of a High Mobility Group-Related Molecule to −315T

Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses

The Human β-Defensins (-1, -2, -3, -4) and Cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK Activation in Primary Human Keratinocytes

Smad3 Deficiency in Mast Cells Provides Efficient Host Protection against Acute Septic Peritonitis

Mast Cells Acquire Monocyte-Specific Gene Expression and Monocyte-Like Morphology by Overproduction of PU.1

Polymorphisms in the FcεRIβ Promoter Region Affecting Transcription Activity: A Possible Promoter-Dependent Mechanism for Association between FcεRIβ and Atopy

A Novel −66T/C Polymorphism in FcεRI α-Chain Promoter Affecting the Transcription Activity: Possible Relationship to Allergic Diseases

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