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Journal Articles

Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27–Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin

Kyosuke Kanai, Ah-Mee Park, Akiko Watanabe, Tomohiro Arikawa, Teruhito Yasui, Hiroki Yoshida, Ikuo Tsunoda, Osamu Yoshie
Journal: The Journal of Immunology
J Immunol (2018) 200 (8): 2703–2713.
https://doi.org/10.4049/jimmunol.1700412
Published: 15 April 2018
View article titled, Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27–Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin
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Includes: Supplementary data
Journal Articles

IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice

Kyosuke Kanai, Ah-Mee Park, Hiroki Yoshida, Ikuo Tsunoda, Osamu Yoshie
Journal: The Journal of Immunology
J Immunol (2017) 198 (1): 119–127.
https://doi.org/10.4049/jimmunol.1600506
Published: 01 January 2017
View article titled, IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice
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Journal Articles

IL-1 released by skn dendritic cells activated through Syk and CARD9 pathway is essential for the sensitization of allergic contact dermatitis. (P6245)

Hiromitsu Hara, Shinsuke Yasukawa, Masutaka Furue, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 181.5.
https://doi.org/10.4049/jimmunol.190.Supp.181.5
Published: 01 May 2013
View article titled, IL-1 released by skn dendritic cells activated through Syk and CARD9 pathway is essential for the sensitization of allergic contact dermatitis. (P6245)
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Journal Articles

IL-17 Is Necessary for Host Protection against Acute-Phase Trypanosoma cruzi Infection

Yoshiyuki Miyazaki, Shinjiro Hamano, Seng Wang, Yohei Shimanoe, Yoichiro Iwakura, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2010) 185 (2): 1150–1157.
https://doi.org/10.4049/jimmunol.0900047
Published: 15 July 2010
View article titled, IL-17 Is Necessary for Host Protection against Acute-Phase <em>Trypanosoma cruzi</em> Infection
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Includes: Supplementary data
Journal Articles

SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis

Mako Nakaya, Masayuki Hashimoto, Ryusuke Nakagawa, Yu Wakabayashi, Takuma Ishizaki, Ichiro Takada, Kyoko Komai, Hiroki Yoshida, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2009) 183 (11): 7047–7053.
https://doi.org/10.4049/jimmunol.0900547
Published: 01 December 2009
View article titled, SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis
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Journal Articles

IL-27 Abrogates Receptor Activator of NF-κB Ligand-Mediated Osteoclastogenesis of Human Granulocyte-Macrophage Colony-Forming Unit Cells through STAT1-Dependent Inhibition of c-Fos

Mitsuru Furukawa, Hironari Takaishi, Jiro Takito, Masaki Yoda, Sadaoki Sakai, Tomohiro Hikata, Akihiro Hakozaki, Shinichi Uchikawa, Morio Matsumoto, Kazuhiro Chiba, Tokuhiro Kimura, Yasunori Okada, Koichi Matsuo, Hiroki Yoshida, Yoshiaki Toyama
Journal: The Journal of Immunology
J Immunol (2009) 183 (4): 2397–2406.
https://doi.org/10.4049/jimmunol.0802091
Published: 15 August 2009
View article titled, IL-27 Abrogates Receptor Activator of NF-κB Ligand-Mediated Osteoclastogenesis of Human Granulocyte-Macrophage Colony-Forming Unit Cells through STAT1-Dependent Inhibition of c-Fos
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Journal Articles

Cell Type-Specific Regulation of ITAM-Mediated NF-κB Activation by the Adaptors, CARMA1 and CARD9

Hiromitsu Hara, Chitose Ishihara, Arata Takeuchi, Liquan Xue, Stephan W. Morris, Josef M. Penninger, Hiroki Yoshida, Takashi Saito
Journal: The Journal of Immunology
J Immunol (2008) 181 (2): 918–930.
https://doi.org/10.4049/jimmunol.181.2.918
Published: 15 July 2008
View article titled, Cell Type-Specific Regulation of ITAM-Mediated NF-κB Activation by the Adaptors, CARMA1 and CARD9
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Journal Articles

Augmentation of Antigen-Presenting and Th1-Promoting Functions of Dendritic Cells by WSX-1(IL-27R) Deficiency

Sen Wang, Yoshiyuki Miyazaki, Yukari Shinozaki, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 6421–6428.
https://doi.org/10.4049/jimmunol.179.10.6421
Published: 15 November 2007
View article titled, Augmentation of Antigen-Presenting and Th1-Promoting Functions of Dendritic Cells by WSX-1(IL-27R) Deficiency
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Journal Articles

Interleukin-17 plays a role in successful resolution of Trypanosoma cruzi infection. (43.17)

Hiroki Yoshida, Sen Wang, Yoichiro Iwakura, Yoshiyuki Miyazaki
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S39.
https://doi.org/10.4049/jimmunol.178.Supp.43.17
Published: 01 April 2007
View article titled, Interleukin-17 plays a role in successful resolution of <em>Trypanosoma cruzi</em> infection. (43.17)
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Journal Articles

Two-Sided Roles of IL-27: Induction of Th1 Differentiation on Naive CD4+ T Cells versus Suppression of Proinflammatory Cytokine Production Including IL-23-Induced IL-17 on Activated CD4+ T Cells Partially Through STAT3-Dependent Mechanism

Takeru Yoshimura, Atsunobu Takeda, Shinjiro Hamano, Yoshiyuki Miyazaki, Ichiko Kinjyo, Tatsuro Ishibashi, Akihiko Yoshimura, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2006) 177 (8): 5377–5385.
https://doi.org/10.4049/jimmunol.177.8.5377
Published: 15 October 2006
View article titled, Two-Sided Roles of IL-27: Induction of Th1 Differentiation on Naive CD4<sup>+</sup> T Cells versus Suppression of Proinflammatory Cytokine Production Including IL-23-Induced IL-17 on Activated CD4<sup>+</sup> T Cells Partially Through STAT3-Dependent Mechanism
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Journal Articles

Membranous Glomerulonephritis Development with Th2-Type Immune Deviations in MRL/lpr Mice Deficient for IL-27 Receptor (WSX-1)

Sakiko Shimizu, Naonobu Sugiyama, Kohsuke Masutani, Atsushi Sadanaga, Yoshiyuki Miyazaki, Yasushi Inoue, Mitsuteru Akahoshi, Ritsuko Katafuchi, Hideki Hirakata, Mine Harada, Shinjiro Hamano, Hitoshi Nakashima, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2005) 175 (11): 7185–7192.
https://doi.org/10.4049/jimmunol.175.11.7185
Published: 01 December 2005
View article titled, Membranous Glomerulonephritis Development with Th2-Type Immune Deviations in MRL/<em>lpr</em> Mice Deficient for IL-27 Receptor (WSX-1)
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Journal Articles

Exacerbation of Experimental Allergic Asthma by Augmented Th2 Responses in WSX-1-Deficient Mice

Yoshiyuki Miyazaki, Hiromasa Inoue, Mikiko Matsumura, Koichiro Matsumoto, Takako Nakano, Miyuki Tsuda, Shinjiro Hamano, Akihiko Yoshimura, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2005) 175 (4): 2401–2407.
https://doi.org/10.4049/jimmunol.175.4.2401
Published: 15 August 2005
View article titled, Exacerbation of Experimental Allergic Asthma by Augmented Th2 Responses in WSX-1-Deficient Mice
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Journal Articles

The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis

Christoph Hölscher, Alexandra Hölscher, Dominik Rückerl, Takayuki Yoshimoto, Hiroki Yoshida, Tak Mak, Christiaan Saris, Stefan Ehlers
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3534–3544.
https://doi.org/10.4049/jimmunol.174.6.3534
Published: 15 March 2005
View article titled, The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis
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Journal Articles

The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

David Artis, Alejandro Villarino, Michael Silverman, Weimian He, Elizabeth M. Thornton, Sharon Mu, Shamin Summer, Todd M. Covey, Elaine Huang, Hiroki Yoshida, Gary Koretzky, Michael Goldschmidt, Gary D. Wu, Fred de Sauvage, Hugh R. P. Miller, Christiaan J. M. Saris, Phillip Scott, Christopher A. Hunter
Journal: The Journal of Immunology
J Immunol (2004) 173 (9): 5626–5634.
https://doi.org/10.4049/jimmunol.173.9.5626
Published: 01 November 2004
View article titled, The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity
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Journal Articles

WSX-1: A Key Role in Induction of Chronic Intestinal Nematode Infection

Allison J. Bancroft, Neil E. Humphreys, John J. Worthington, Hiroki Yoshida, Richard K. Grencis
Journal: The Journal of Immunology
J Immunol (2004) 172 (12): 7635–7641.
https://doi.org/10.4049/jimmunol.172.12.7635
Published: 15 June 2004
View article titled, WSX-1: A Key Role in Induction of Chronic Intestinal Nematode Infection
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Journal Articles

Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis

Atsushi Yamanaka, Shinjiro Hamano, Yoshiyuki Miyazaki, Kazunari Ishii, Atsunobu Takeda, Tak W. Mak, Kunisuke Himeno, Akihiko Yoshimura, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2004) 172 (6): 3590–3596.
https://doi.org/10.4049/jimmunol.172.6.3590
Published: 15 March 2004
View article titled, Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis
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Journal Articles

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

Atsunobu Takeda, Shinjiro Hamano, Atsushi Yamanaka, Toshikatsu Hanada, Tatsuro Ishibashi, Tak W. Mak, Akihiko Yoshimura, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2003) 170 (10): 4886–4890.
https://doi.org/10.4049/jimmunol.170.10.4886
Published: 15 May 2003
View article titled, Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment
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Journal Articles

The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes

Hiromitsu Hara, Atsunobu Takeda, Michiyo Takeuchi, Andrew C. Wakeham, Annick Itié, Masafumi Sasaki, Tak W. Mak, Akihiko Yoshimura, Kikuo Nomoto, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2002) 168 (8): 4241.
https://doi.org/10.4049/jimmunol.168.8.4241
Published: 15 April 2002
View article titled, The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes
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Journal Articles

The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes

Hiromitsu Hara, Atsunobu Takeda, Michiyo Takeuchi, Andrew C. Wakeham, Annick Itié, Masafumi Sasaki, Tak W. Mak, Akihiko Yoshimura, Kikuo Nomoto, Hiroki Yoshida
Journal: The Journal of Immunology
J Immunol (2002) 168 (5): 2288–2295.
https://doi.org/10.4049/jimmunol.168.5.2288
Published: 01 March 2002
View article titled, The Apoptotic Protease-Activating Factor 1-Mediated Pathway of Apoptosis Is Dispensable for Negative Selection of Thymocytes
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Journal Articles

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions

Gordon S. Duncan, David P. Andrew, Hiroaki Takimoto, Stephen A. Kaufman, Hiroki Yoshida, Jason Spellberg, José Luis de la Pompa, Andrew Elia, Andrew Wakeham, Barbara Karan-Tamir, William A. Muller, Giorgio Senaldi, Mark M. Zukowski, Tak W. Mak
Journal: The Journal of Immunology
J Immunol (1999) 162 (5): 3022–3030.
https://doi.org/10.4049/jimmunol.162.5.3022
Published: 01 March 1999
View article titled, Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions
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