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Hiroshi Kiyono
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Journal Articles

Development of Nanogel-based Nasal Vaccine against Pneumonia

Rika Nakahashi, Yoshikazu Yuki, Kohtaro Fujihashi, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 166.2.
https://doi.org/10.4049/jimmunol.204.Supp.166.2
Published: 01 May 2020
View article titled, Development of Nanogel-based Nasal Vaccine against Pneumonia
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Transient Suppression and Functional Modulation of Mucosal Mast Cells for the Treatment of Allergic Disease

Yosuke Kurashima, Yoshihiro Takasato, Masahiro Kiuchi, Kiyoshi Hirahara, Sayuri Murasaki, Jun Kunisawa, Masato Kubo, Toshinori Nakayama, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 54.3.
https://doi.org/10.4049/jimmunol.202.Supp.54.3
Published: 01 May 2019
View article titled, Transient Suppression and Functional Modulation of Mucosal Mast Cells for the Treatment of Allergic Disease
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Loss of Lymph Node Fibroblastic Reticular Cells and High Endothelial Cells Is Associated with Humoral Immunodeficiency in Mouse Graft-versus-Host Disease

Fumiko Suenaga, Satoshi Ueha, Jun Abe, Mizuha Kosugi-Kanaya, Yong Wang, Akihiro Yokoyama, Yusuke Shono, Francis H. W. Shand, Yasuyuki Morishita, Jun Kunisawa, Shintaro Sato, Hiroshi Kiyono, Kouji Matsushima
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 398–406.
https://doi.org/10.4049/jimmunol.1401022
Published: 01 January 2015
View article titled, Loss of Lymph Node Fibroblastic Reticular Cells and High Endothelial Cells Is Associated with Humoral Immunodeficiency in Mouse Graft-versus-Host Disease
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Includes: Supplementary data
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Regulation of Intestinal IgA Responses by Dietary Palmitic Acid and Its Metabolism

Jun Kunisawa, Eri Hashimoto, Asuka Inoue, Risa Nagasawa, Yuji Suzuki, Izumi Ishikawa, Shiori Shikata, Makoto Arita, Junken Aoki, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 1666–1671.
https://doi.org/10.4049/jimmunol.1302944
Published: 15 August 2014
View article titled, Regulation of Intestinal IgA Responses by Dietary Palmitic Acid and Its Metabolism
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Includes: Supplementary data
Journal Articles

Nanogel-based PspA nasal vaccine induces microRNA-associated protective immunity in nonhuman primates (MUC4P.834)

Yoshiko Fukuyama, Yoshikazu Yuki, Yuko Katakai, Haruko Takahashi, Shinichi Sawada, Sunyi Joo, Eun Jeong Park, Kazunari Akiyoshi, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 133.10.
https://doi.org/10.4049/jimmunol.192.Supp.133.10
Published: 01 May 2014
View article titled, Nanogel-based PspA nasal vaccine induces microRNA-associated protective immunity in nonhuman primates (MUC4P.834)
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Journal Articles

Critical Role of Dendritic Cells in T Cell Retention in the Interfollicular Region of Peyer’s Patches

Takashi Obata, Naoko Shibata, Yoshiyuki Goto, Izumi Ishikawa, Shintaro Sato, Jun Kunisawa, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2013) 191 (2): 942–948.
https://doi.org/10.4049/jimmunol.1200636
Published: 15 July 2013
View article titled, Critical Role of Dendritic Cells in T Cell Retention in the Interfollicular Region of Peyer’s Patches
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Includes: Supplementary data
Journal Articles

Ecto-Nucleoside Triphosphate Diphosphohydrolase 7 Controls Th17 Cell Responses through Regulation of Luminal ATP in the Small Intestine

Takashi Kusu, Hisako Kayama, Makoto Kinoshita, Seong Gyu Jeon, Yoshiyasu Ueda, Yoshiyuki Goto, Ryu Okumura, Hiroyuki Saiga, Takashi Kurakawa, Kayo Ikeda, Yuichi Maeda, Jun-ichi Nishimura, Yasunobu Arima, Koji Atarashi, Kenya Honda, Masaaki Murakami, Jun Kunisawa, Hiroshi Kiyono, Meinoshin Okumura, Masahiro Yamamoto, Kiyoshi Takeda
Journal: The Journal of Immunology
J Immunol (2013) 190 (2): 774–783.
https://doi.org/10.4049/jimmunol.1103067
Published: 15 January 2013
View article titled, Ecto-Nucleoside Triphosphate Diphosphohydrolase 7 Controls Th17 Cell Responses through Regulation of Luminal ATP in the Small Intestine
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Includes: Supplementary data
Journal Articles

Dietary Folic Acid Promotes Survival of Foxp3+ Regulatory T Cells in the Colon

Makoto Kinoshita, Hisako Kayama, Takashi Kusu, Tomoyuki Yamaguchi, Jun Kunisawa, Hiroshi Kiyono, Shimon Sakaguchi, Kiyoshi Takeda
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2869–2878.
https://doi.org/10.4049/jimmunol.1200420
Published: 15 September 2012
View article titled, Dietary Folic Acid Promotes Survival of Foxp3<sup>+</sup> Regulatory T Cells in the Colon
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Includes: Supplementary data
Journal Articles

Development of Mature and Functional Human Myeloid Subsets in Hematopoietic Stem Cell-Engrafted NOD/SCID/IL2rγKO Mice

Satoshi Tanaka, Yoriko Saito, Jun Kunisawa, Yosuke Kurashima, Taichi Wake, Nahoko Suzuki, Leonard D. Shultz, Hiroshi Kiyono, Fumihiko Ishikawa
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6145–6155.
https://doi.org/10.4049/jimmunol.1103660
Published: 15 June 2012
View article titled, Development of Mature and Functional Human Myeloid Subsets in Hematopoietic Stem Cell-Engrafted NOD/SCID/IL2rγKO Mice
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Includes: Supplementary data
Journal Articles

Oral tolerance induction does not resolve allergic enteropathy due to residual IgE (125.7)

Masako Toda, Manja Burggraf, Haruyo Nakajima-Adachi, Satoshi Hachimura, Maren Krause, Hiroshi Kiyono, Gröne Hermann-Josef, Stefan Vieths
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 125.7.
https://doi.org/10.4049/jimmunol.188.Supp.125.7
Published: 01 May 2012
View article titled, Oral tolerance induction does not resolve allergic enteropathy due to residual IgE (125.7)
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Journal Articles

Adjuvant-free nanogel-based PspA nasal vaccine for the induction of protective immunity against Pneumococcus (166.7)

Yoshikazu Yuki, Il Kong, Ayuko Sato, Tomonori Nochi, Mio Mejima, Shiho Kurokawa, Tomoko Hiroiwa, Yoshiko Fukuyama, Shinichi Sawada, Haruko Takahashi, Kazunari Akiyoshi, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 166.7.
https://doi.org/10.4049/jimmunol.188.Supp.166.7
Published: 01 May 2012
View article titled, Adjuvant-free nanogel-based PspA nasal vaccine for the induction of protective immunity against Pneumococcus (166.7)
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Journal Articles

Vitamin B1 is an essential survival factor for naïve B cells but not IgA-secreting plasma cells (120.9)

Taichi Wake, Jun Kunisawa, Eri Hashimoto, Yuji Suzuki, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 120.9.
https://doi.org/10.4049/jimmunol.188.Supp.120.9
Published: 01 May 2012
View article titled, Vitamin B1 is an essential survival factor for naïve B cells but not IgA-secreting plasma cells (120.9)
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Journal Articles

Dietary vitamin B9 is a survival factor of intestinal regulatory T cells (166.2)

Jun Kunisawa, Eri Hashimoto, Izumi Ishikawa, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 166.2.
https://doi.org/10.4049/jimmunol.186.Supp.166.2
Published: 01 April 2011
View article titled, Dietary vitamin B9 is a survival factor of intestinal regulatory T cells (166.2)
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Unique pathways of purinergic P2X7 receptor-mediated colonic mast cell activation in the intestinal inflammation (166.9)

Yosuke Kurashima, Takeaki Amiya, Jun Kunisawa, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 166.9.
https://doi.org/10.4049/jimmunol.186.Supp.166.9
Published: 01 April 2011
View article titled, Unique pathways of purinergic P2X7 receptor-mediated colonic mast cell activation in the intestinal inflammation (166.9)
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Journal Articles

Specific comensal bacteria modulate epithelial glycosylaion (59.5)

Yoshiyuki Goto, Yoshinori Umesaki, Yoshimi Benno, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 59.5.
https://doi.org/10.4049/jimmunol.186.Supp.59.5
Published: 01 April 2011
View article titled, Specific comensal bacteria modulate epithelial glycosylaion (59.5)
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In vivo molecular imaging for a nasal botulism vaccine in mice and nonhuman primates (53.8)

Yoshikazu Yuki, Tomonori Nochi, Norihiro Harada, Yuko Katakai, Mio Mejima, Daisuke Tokuhara, Shiho Kurokawa, Yuko Takahashi, Hiroaki Shibata, Tomoko Kohda, Shunji Kozaki, Hideo Tsukada, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 53.8.
https://doi.org/10.4049/jimmunol.186.Supp.53.8
Published: 01 April 2011
View article titled, In vivo molecular imaging for a nasal botulism vaccine in mice and nonhuman primates (53.8)
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Passive oral rice-based antibody prophylaxis and therapy against rotavirus infection (106.19)

Daisuke Tokuhara, Beatriz Gonzalez, Mio Mejima, Yuko Takahashi, Shiho Kurokawa, Tomoko Hiroiwa, Masaharu Kuroda, Masaaki Oyama, Hiroko Kozuka-Hata, Tomonori Nochi, Farah Aladin, Harold Marcotte, Leon Frenken, Miren Iturriza, Hiroshi Kiyono, Lennart Hammarstrom, Yoshikazu Yuki
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 106.19.
https://doi.org/10.4049/jimmunol.186.Supp.106.19
Published: 01 April 2011
View article titled, Passive oral rice-based antibody prophylaxis and therapy against rotavirus infection (106.19)
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The Airway Antigen Sampling System: Respiratory M Cells as an Alternative Gateway for Inhaled Antigens

Dong-Young Kim, Ayuko Sato, Satoshi Fukuyama, Hiroshi Sagara, Takahiro Nagatake, Il Gyu Kong, Kaoru Goda, Tomonori Nochi, Jun Kunisawa, Shintaro Sato, Yoshifumi Yokota, Chul Hee Lee, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 4253–4262.
https://doi.org/10.4049/jimmunol.0903794
Published: 01 April 2011
View article titled, The Airway Antigen Sampling System: Respiratory M Cells as an Alternative Gateway for Inhaled Antigens
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Includes: Multimedia, Supplementary data
Journal Articles

In Vivo Molecular Imaging Analysis of a Nasal Vaccine That Induces Protective Immunity against Botulism in Nonhuman Primates

Yoshikazu Yuki, Tomonori Nochi, Norihiro Harada, Yuko Katakai, Hiroaki Shibata, Mio Mejima, Tomoko Kohda, Daisuke Tokuhara, Shiho Kurokawa, Yuko Takahashi, Fumiko Ono, Shunji Kozaki, Keiji Terao, Hideo Tsukada, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2010) 185 (9): 5436–5443.
https://doi.org/10.4049/jimmunol.1001789
Published: 01 November 2010
View article titled, In Vivo Molecular Imaging Analysis of a Nasal Vaccine That Induces Protective Immunity against Botulism in Nonhuman Primates
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Includes: Multimedia, Supplementary data
Journal Articles

Secretory IgA responses induced by rice-based oral cholera toxin B subunit vaccine are solely responsible for antibody-mediated long-standing cross-protection against Vibrio cholerae - and enterotoxigenic Escherichia coli -induced diarrhea (46.3)

Daisuke Tokuhara, Yoshikazu Yuki, Tomonori Nochi, Toshio Kodama, Mio Mejima, Shiho Kurokawa, Yuko Takahashi, Masanobu Nanno, Fumio Takaiwa, Takeshi Honda, Hiroshi Kiyono
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 46.3.
https://doi.org/10.4049/jimmunol.184.Supp.46.3
Published: 01 April 2010
View article titled, Secretory IgA responses induced by rice-based oral cholera toxin B subunit vaccine are solely responsible for antibody-mediated long-standing cross-protection against <em> Vibrio cholerae </em>- and enterotoxigenic <em> Escherichia coli </em>-induced diarrhea (46.3)
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