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Hitoshi Kikutani
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Journal Articles

Multiple tolerance checkpoints suppress low-affinity germline precursor B cells of high affinity anti-dsDNA antibody-producing cells in BCR knock-in mice

Marwa Ali El Hussien Mohammed, Shuhei Sakakibara, Chau-Yuan Tsai, Hitoshi Kikutani
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 218.9.
https://doi.org/10.4049/jimmunol.204.Supp.218.9
Published: 01 May 2020
View article titled, Multiple tolerance checkpoints suppress low-affinity germline precursor B cells of high affinity anti-dsDNA antibody-producing cells in BCR knock-in mice
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Journal Articles

Cutting Edge: Critical Role of IκB Kinase α in TLR7/9-Induced Type I IFN Production by Conventional Dendritic Cells

Katsuaki Hoshino, Izumi Sasaki, Takahiro Sugiyama, Takahiro Yano, Chihiro Yamazaki, Teruhito Yasui, Hitoshi Kikutani, Tsuneyasu Kaisho
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3341–3345.
https://doi.org/10.4049/jimmunol.0901648
Published: 01 April 2010
View article titled, Cutting Edge: Critical Role of IκB Kinase α in TLR7/9-Induced Type I IFN Production by Conventional Dendritic Cells
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Includes: Supplementary data
Journal Articles

Roles of Sema4D–Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis

Tatsusada Okuno, Yuji Nakatsuji, Masayuki Moriya, Hyota Takamatsu, Satoshi Nojima, Noriko Takegahara, Toshihiko Toyofuku, Yukinobu Nakagawa, Sujin Kang, Roland H. Friedel, Saburo Sakoda, Hitoshi Kikutani, Atsushi Kumanogoh
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1499–1506.
https://doi.org/10.4049/jimmunol.0903302
Published: 28 December 2009
View article titled, Roles of Sema4D–Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis
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Includes: Supplementary data
Journal Articles

CD100 Enhances Dendritic Cell and CD4+ Cell Activation Leading to Pathogenetic Humoral Responses and Immune Complex Glomerulonephritis

Ming Li, Kim M. O’Sullivan, Lynelle K. Jones, Timothy Semple, Atsushi Kumanogoh, Hitoshi Kikutani, Stephen R. Holdsworth, A. Richard Kitching
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 3406–3412.
https://doi.org/10.4049/jimmunol.177.5.3406
Published: 01 September 2006
View article titled, CD100 Enhances Dendritic Cell and CD4<sup>+</sup> Cell Activation Leading to Pathogenetic Humoral Responses and Immune Complex Glomerulonephritis
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Journal Articles

Requirement for the Lymphocyte Semaphorin, CD100, in the Induction of Antigen-Specific T Cells and the Maturation of Dendritic Cells

Atsushi Kumanogoh, Kazuhiro Suzuki, EweSeng Ch’ng, Chie Watanabe, Satoko Marukawa, Noriko Takegahara, Isao Ishida, Takehito Sato, Sonoko Habu, Kanji Yoshida, Wei Shi, Hitoshi Kikutani
Journal: The Journal of Immunology
J Immunol (2002) 169 (3): 1175–1181.
https://doi.org/10.4049/jimmunol.169.3.1175
Published: 01 August 2002
View article titled, Requirement for the Lymphocyte Semaphorin, CD100, in the Induction of Antigen-Specific T Cells and the Maturation of Dendritic Cells
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Journal Articles

Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease

Tetsuya Higuchi, Yuichi Aiba, Takashi Nomura, Junichiro Matsuda, Keiji Mochida, Misao Suzuki, Hitoshi Kikutani, Tasuku Honjo, Kiyoshi Nishioka, Takeshi Tsubata
Journal: The Journal of Immunology
J Immunol (2002) 168 (1): 9–12.
https://doi.org/10.4049/jimmunol.168.1.9
Published: 01 January 2002
View article titled, Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease
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Journal Articles

Enhanced Immune Responses in Transgenic Mice Expressing a Truncated Form of the Lymphocyte Semaphorin CD100

Chie Watanabe, Atsushi Kumanogoh, Wei Shi, Kazuhiro Suzuki, Shuichi Yamada, Masaru Okabe, Kanji Yoshida, Hitoshi Kikutani
Journal: The Journal of Immunology
J Immunol (2001) 167 (8): 4321–4328.
https://doi.org/10.4049/jimmunol.167.8.4321
Published: 15 October 2001
View article titled, Enhanced Immune Responses in Transgenic Mice Expressing a Truncated Form of the Lymphocyte Semaphorin CD100
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Journal Articles

Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development

Atsushi Kumanogoh, Xiaosong Wang, Ihnsook Lee, Chie Watanabe, Masahito Kamanaka, Wei Shi, Kanji Yoshida, Takehito Sato, Sonoko Habu, Misako Itoh, Noriko Sakaguchi, Shimon Sakaguchi, Hitoshi Kikutani
Journal: The Journal of Immunology
J Immunol (2001) 166 (1): 353–360.
https://doi.org/10.4049/jimmunol.166.1.353
Published: 01 January 2001
View article titled, Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development
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Journal Articles

CD4+ T Cell Responses to CD40-Deficient APCs: Defects in Proliferation and Negative Selection Apply Only with B Cells as APCs

Minette E. Ozaki, Barbara A. Coren, Tracy N. Huynh, Deborah J. Redondo, Hitoshi Kikutani, Susan R. Webb
Journal: The Journal of Immunology
J Immunol (1999) 163 (10): 5250–5256.
https://doi.org/10.4049/jimmunol.163.10.5250
Published: 15 November 1999
View article titled, CD4<sup>+</sup> T Cell Responses to CD40-Deficient APCs: Defects in Proliferation and Negative Selection Apply Only with B Cells as APCs
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Journal Articles

Cutting Edge: Dendritic Cells Require Maturation via CD40 to Generate Protective Antitumor Immunity

Matthew F. Mackey, Jason R. Gunn, Charles Maliszewski, Hitoshi Kikutani, Randolph J. Noelle, Richard J. Barth, Jr.
Journal: The Journal of Immunology
J Immunol (1998) 161 (5): 2094–2098.
https://doi.org/10.4049/jimmunol.161.5.2094
Published: 01 September 1998
View article titled, Cutting Edge: Dendritic Cells Require Maturation via CD40 to Generate Protective Antitumor Immunity
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Journal Articles

Involvement of Anti-Ig-Activated Serine Protease in the Generation of Cytoplasmic Factor(s) that Are Responsible for the Transmission of Ig-Receptor-Mediated Signals

Tadamitsu Kishimoto, Hitoshi Kikutani, Yoshio Nishizawa, Nobuo Sakaguchi, Yuichi Yamamura
Journal: The Journal of Immunology
J Immunol (1979) 123 (4): 1504–1510.
https://doi.org/10.4049/jimmunol.123.4.1504
Published: 01 October 1979
View article titled, Involvement of Anti-Ig-Activated Serine Protease in the Generation of Cytoplasmic Factor(s) that Are Responsible for the Transmission of Ig-Receptor-Mediated Signals
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Journal Articles

Biphasic Effect of Cyclic AMP on IgG Production and on the Changes of Non-Histone Nuclear Proteins Induced with Anti-Immunoglobulin and Enhancing Soluble Factor

Tadamitsu Kishimoto, Yoshio Nishizawa, Hitoshi Kikutani, Yuichi Yamamura
Journal: The Journal of Immunology
J Immunol (1977) 118 (6): 2027–2033.
https://doi.org/10.4049/jimmunol.118.6.2027
Published: 01 June 1977
View article titled, Biphasic Effect of Cyclic AMP on IgG Production and on the Changes of Non-Histone Nuclear Proteins Induced with Anti-Immunoglobulin and Enhancing Soluble Factor
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