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Isao Nagaoka
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Journal Articles

Human Cathelicidin Peptide LL-37 Induces Cell Death in Autophagy-Dysfunctional Endothelial Cells

Kaori Suzuki, Mari Ohkuma, Akimasa Someya, Tomoya Mita, Isao Nagaoka
Journal: The Journal of Immunology
J Immunol (2022) 208 (9): 2163–2172.
https://doi.org/10.4049/jimmunol.2100050
Published: 01 May 2022
View article titled, Human Cathelicidin Peptide LL-37 Induces Cell Death in Autophagy-Dysfunctional Endothelial Cells
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Includes: Supplementary data
Journal Articles

Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation

Kaori Suzuki, Taisuke Murakami, Zhongshuang Hu, Hiroshi Tamura, Kyoko Kuwahara-Arai, Toshiaki Iba, Isao Nagaoka
Journal: The Journal of Immunology
J Immunol (2016) 196 (3): 1338–1347.
https://doi.org/10.4049/jimmunol.1403203
Published: 01 February 2016
View article titled, Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation
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Includes: Supplementary data
Journal Articles

Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

François Niyonsaba, Hiroko Ushio, Mutsuko Hara, Hidenori Yokoi, Mitsutoshi Tominaga, Kenji Takamori, Naoki Kajiwara, Hirohisa Saito, Isao Nagaoka, Hideoki Ogawa, Ko Okumura
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3526–3534.
https://doi.org/10.4049/jimmunol.0900712
Published: 01 April 2010
View article titled, Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells
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Journal Articles

An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X7

Isao Nagaoka, Hiroshi Tamura, Michimasa Hirata
Journal: The Journal of Immunology
J Immunol (2006) 176 (5): 3044–3052.
https://doi.org/10.4049/jimmunol.176.5.3044
Published: 01 March 2006
View article titled, An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X<sub>7</sub>
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Journal Articles

The Human β-Defensins (-1, -2, -3, -4) and Cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK Activation in Primary Human Keratinocytes

François Niyonsaba, Hiroko Ushio, Isao Nagaoka, Ko Okumura, Hideoki Ogawa
Journal: The Journal of Immunology
J Immunol (2005) 175 (3): 1776–1784.
https://doi.org/10.4049/jimmunol.175.3.1776
Published: 01 August 2005
View article titled, The Human β-Defensins (-1, -2, -3, -4) and Cathelicidin LL-37 Induce IL-18 Secretion through p38 and ERK MAPK Activation in Primary Human Keratinocytes
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Journal Articles

Modulation of Human β-Defensin-2 Transcription in Pulmonary Epithelial Cells by Lipopolysaccharide-Stimulated Mononuclear Phagocytes Via Proinflammatory Cytokine Production

Yuko Tsutsumi-Ishii, Isao Nagaoka
Journal: The Journal of Immunology
J Immunol (2003) 170 (8): 4226–4236.
https://doi.org/10.4049/jimmunol.170.8.4226
Published: 15 April 2003
View article titled, Modulation of Human β-Defensin-2 Transcription in Pulmonary Epithelial Cells by Lipopolysaccharide-Stimulated Mononuclear Phagocytes Via Proinflammatory Cytokine Production
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Journal Articles

Cathelicidin Family of Antibacterial Peptides CAP18 and CAP11 Inhibit the Expression of TNF-α by Blocking the Binding of LPS to CD14+ Cells

Isao Nagaoka, Satoko Hirota, François Niyonsaba, Michimasa Hirata, Yoshiyuki Adachi, Hiroshi Tamura, Didier Heumann
Journal: The Journal of Immunology
J Immunol (2001) 167 (6): 3329–3338.
https://doi.org/10.4049/jimmunol.167.6.3329
Published: 15 September 2001
View article titled, Cathelicidin Family of Antibacterial Peptides CAP18 and CAP11 Inhibit the Expression of TNF-α by Blocking the Binding of LPS to CD14<sup>+</sup> Cells
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Journal Articles

Role of CCAAT/Enhancer-Binding Protein Site in Transcription of Human Neutrophil Peptide-1 and -3 Defensin Genes

Yuko Tsutsumi-Ishii, Takeshi Hasebe, Isao Nagaoka
Journal: The Journal of Immunology
J Immunol (2000) 164 (6): 3264–3273.
https://doi.org/10.4049/jimmunol.164.6.3264
Published: 15 March 2000
View article titled, Role of CCAAT/Enhancer-Binding Protein Site in Transcription of Human Neutrophil Peptide-1 and -3 Defensin Genes
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Journal Articles

Cutting Edge: Chemotactic Activity of Soluble Fas Ligand Against Phagocytes

Ken-ichiro Seino, Kazuhisa Iwabuchi, Nobuhiko Kayagaki, Ryukou Miyata, Isao Nagaoka, Akio Matsuzawa, Katashi Fukao, Hideo Yagita, Ko Okumura
Journal: The Journal of Immunology
J Immunol (1998) 161 (9): 4484–4488.
https://doi.org/10.4049/jimmunol.161.9.4484
Published: 01 November 1998
View article titled, Cutting Edge: Chemotactic Activity of Soluble Fas Ligand Against Phagocytes
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