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Jürgen Scheller
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Journal Articles

Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging

Puyan Rafii, Friedrich Reusswig, Julia Werner, Haifeng Xu, Philpp A. Lang, Stefan Rose-John, Simone Gorressen, Christina Alter, Jürgen Schrader, Diran Herebian, Doreen M. Floss, Margitta Elvers, Roland P. Piekorz, Jürgen Scheller, Kristina Behnke
Journal: The Journal of Immunology
J Immunol (2023) 210 (11): 1641–1652.
https://doi.org/10.4049/jimmunol.2200788
Published: 14 April 2023
View article titled, Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging
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Includes: Supplementary data
Journal Articles

Investigation of Fascin1, a Marker of Mature Dendritic Cells, Reveals a New Role for IL-6 Signaling in CCR7-Mediated Chemotaxis

Fumio Matsumura, Robin Polz, Sukhwinder Singh, Aya Matsumura, Jürgen Scheller, Shigeko Yamashiro
Journal: The Journal of Immunology
J Immunol (2021) 207 (3): 938–949.
https://doi.org/10.4049/jimmunol.2000318
Published: 01 August 2021
View article titled, Investigation of Fascin1, a Marker of Mature Dendritic Cells, Reveals a New Role for IL-6 Signaling in CCR7-Mediated Chemotaxis
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Journal Articles

Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation

Neele Schumacher, Stefanie Schmidt, Jeanette Schwarz, Dana Dohr, Juliane Lokau, Jürgen Scheller, Christoph Garbers, Athena Chalaris, Stefan Rose-John, Björn Rabe
Journal: The Journal of Immunology
J Immunol (2016) 197 (9): 3705–3715.
https://doi.org/10.4049/jimmunol.1600909
Published: 01 November 2016
View article titled, Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation
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Includes: Supplementary data
Journal Articles

The Role of Metalloproteinase ADAM17 in Regulating ICOS Ligand–Mediated Humoral Immune Responses

Joanna Marczynska, Aleksandra Ozga, Agnieszka Wlodarczyk, Monika Majchrzak-Gorecka, Paulina Kulig, Magdalena Banas, Dominika Michalczyk-Wetula, Pawel Majewski, Andreas Hutloff, Jeanette Schwarz, Athena Chalaris, Jürgen Scheller, Stefan Rose-John, Joanna Cichy
Journal: The Journal of Immunology
J Immunol (2014) 193 (6): 2753–2763.
https://doi.org/10.4049/jimmunol.1302893
Published: 15 September 2014
View article titled, The Role of Metalloproteinase ADAM17 in Regulating ICOS Ligand–Mediated Humoral Immune Responses
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Includes: Supplementary data
Journal Articles

“Activated” STAT Proteins: A Paradoxical Consequence of Inhibited JAK-STAT Signaling in Cytomegalovirus-Infected Cells

Mirko Trilling, Vu Thuy Khanh Le, Jassin Rashidi-Alavijeh, Benjamin Katschinski, Jürgen Scheller, Stefan Rose-John, Gabriela Elena Androsiac, Stipan Jonjić, Valeria Poli, Klaus Pfeffer, Hartmut Hengel
Journal: The Journal of Immunology
J Immunol (2014) 192 (1): 447–458.
https://doi.org/10.4049/jimmunol.1203516
Published: 01 January 2014
View article titled, “Activated” STAT Proteins: A Paradoxical Consequence of Inhibited JAK-STAT Signaling in Cytomegalovirus-Infected Cells
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Journal Articles

Trp53 Deficiency Protects against Acute Intestinal Inflammation

Martina E. Spehlmann, Carolin F. Manthey, Sara M. Dann, Elaine Hanson, Sukhman S. Sandhu, Linus Y. Liu, Farid K. Abdelmalak, Michaela A. Diamanti, Kristin Retzlaff, Jürgen Scheller, Stefan Rose-John, Florian R. Greten, Jean Y. J. Wang, Lars Eckmann
Journal: The Journal of Immunology
J Immunol (2013) 191 (2): 837–847.
https://doi.org/10.4049/jimmunol.1201716
Published: 15 July 2013
View article titled, <em>Trp53</em> Deficiency Protects against Acute Intestinal Inflammation
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Includes: Supplementary data
Journal Articles

IL-6 Controls the Innate Immune Response against Listeria monocytogenes via Classical IL-6 Signaling

Judith Hoge, Isabell Yan, Nathalie Jänner, Valéa Schumacher, Athena Chalaris, Oliver M. Steinmetz, Daniel R. Engel, Jürgen Scheller, Stefan Rose-John, Hans-Willi Mittrücker
Journal: The Journal of Immunology
J Immunol (2013) 190 (2): 703–711.
https://doi.org/10.4049/jimmunol.1201044
Published: 15 January 2013
View article titled, IL-6 Controls the Innate Immune Response against <em>Listeria monocytogenes</em> via Classical IL-6 Signaling
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Includes: Supplementary data
Journal Articles

Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells

Gareth W. Jones, Rachel M. McLoughlin, Victoria J. Hammond, Clare R. Parker, John D. Williams, Raj Malhotra, Jürgen Scheller, Anwen S. Williams, Stefan Rose-John, Nicholas Topley, Simon A. Jones
Journal: The Journal of Immunology
J Immunol (2010) 184 (4): 2130–2139.
https://doi.org/10.4049/jimmunol.0901528
Published: 18 January 2010
View article titled, Loss of CD4<sup>+</sup> T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 <em>Trans</em> Signaling in the Local Maintenance of Th17 Cells
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Journal Articles

Essential Roles of IL-6 Trans-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble–IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model

Satoshi Matsumoto, Taeko Hara, Keiichi Mitsuyama, Mayuko Yamamoto, Osamu Tsuruta, Michio Sata, Jürgen Scheller, Stefan Rose-John, Sho-ichi Kado, Toshihiko Takada
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1543–1551.
https://doi.org/10.4049/jimmunol.0801217
Published: 30 December 2009
View article titled, Essential Roles of IL-6 <em>Trans</em>-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble–IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model
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Journal Articles

The impact of defective gp130/SOCS3 signaling on the astrocyte response to hyper-IL6 (38.17)

Ricardo F Frausto, Gareth Denyer, Jurgen Scheller, Stefan Rose-John, Brendan J Jenkins, Matthias Ernst, Iain L Campbell
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 38.17.
https://doi.org/10.4049/jimmunol.182.Supp.38.17
Published: 01 April 2009
View article titled, The impact of defective gp130/SOCS3 signaling on the astrocyte response to hyper-IL6 (38.17)
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