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J A Berzofsky
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Journal Articles

Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with antigen-specific antibody titer, but not with effector CD4+ T cells.

C Hirunpetcharat, J H Tian, D C Kaslow, N van Rooijen, S Kumar, J A Berzofsky, L H Miller, M F Good
Journal: The Journal of Immunology
J Immunol (1997) 159 (7): 3400–3411.
https://doi.org/10.4049/jimmunol.159.7.3400
Published: 01 October 1997
View article titled, Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with antigen-specific antibody titer, but not with effector CD4+ T cells.
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Journal Articles

Immunogenicity and immunopathogenicity of an autoimmune epitope are potentiated by increasing MHC binding through residue substitution.

A T Kozhich, R R Caspi, J A Berzofsky, I Gery
Journal: The Journal of Immunology
J Immunol (1997) 158 (9): 4145–4151.
https://doi.org/10.4049/jimmunol.158.9.4145
Published: 01 May 1997
View article titled, Immunogenicity and immunopathogenicity of an autoimmune epitope are potentiated by increasing MHC binding through residue substitution.
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Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes.

J D Ahlers, N Dunlop, D W Alling, P L Nara, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1997) 158 (8): 3947–3958.
https://doi.org/10.4049/jimmunol.158.8.3947
Published: 15 April 1997
View article titled, Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes.
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Journal Articles

Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.

M Shirai, S Kozlowski, D H Margulies, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1997) 158 (7): 3181–3188.
https://doi.org/10.4049/jimmunol.158.7.3181
Published: 01 April 1997
View article titled, Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.
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Journal Articles

Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160.

M Shirai, K Kurokohchi, C D Pendleton, T Arichi, L F Boyd, H Takahashi, D H Margulies, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1996) 157 (10): 4399–4411.
https://doi.org/10.4049/jimmunol.157.10.4399
Published: 15 November 1996
View article titled, Reciprocal cytotoxic T lymphocyte cross-reactivity interactions between two major epitopes within HIV-1 gp160.
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Journal Articles

Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.

J H Tian, L H Miller, D C Kaslow, J Ahlers, M F Good, D W Alling, J A Berzofsky, S Kumar
Journal: The Journal of Immunology
J Immunol (1996) 157 (3): 1176–1183.
https://doi.org/10.4049/jimmunol.157.3.1176
Published: 01 August 1996
View article titled, Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.
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Journal Articles

Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T cell epitopes.

I F Ciernik, J A Berzofsky, D P Carbone
Journal: The Journal of Immunology
J Immunol (1996) 156 (7): 2369–2375.
https://doi.org/10.4049/jimmunol.156.7.2369
Published: 01 April 1996
View article titled, Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T cell epitopes.
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T cell-derived IL-3 induces the production of IL-4 by non-B, non-T cells to amplify the Th2-cytokine response to a non-parasite antigen in Schistosoma mansoni-infected mice.

M C Kullberg, J A Berzofsky, D L Jankovic, S Barbieri, M E Williams, P Perlmann, A Sher, M Troye-Blomberg
Journal: The Journal of Immunology
J Immunol (1996) 156 (4): 1482–1489.
https://doi.org/10.4049/jimmunol.156.4.1482
Published: 15 February 1996
View article titled, T cell-derived IL-3 induces the production of IL-4 by non-B, non-T cells to amplify the Th2-cytokine response to a non-parasite antigen in Schistosoma mansoni-infected mice.
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Journal Articles

Molecular analysis of a heteroclitic T cell response to the immunodominant epitope of sperm whale myoglobin. Implications for peptide partial agonists.

R D England, M C Kullberg, J L Cornette, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1995) 155 (9): 4295–4306.
https://doi.org/10.4049/jimmunol.155.9.4295
Published: 01 November 1995
View article titled, Molecular analysis of a heteroclitic T cell response to the immunodominant epitope of sperm whale myoglobin. Implications for peptide partial agonists.
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Journal Articles

CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.

M Shirai, T Arichi, M Nishioka, T Nomura, K Ikeda, K Kawanishi, V H Engelhard, S M Feinstone, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1995) 154 (6): 2733–2742.
https://doi.org/10.4049/jimmunol.154.6.2733
Published: 15 March 1995
View article titled, CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.
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Journal Articles

Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites.

I A Quakyi, J Currier, A Fell, D W Taylor, T Roberts, R A Houghten, R D England, J A Berzofsky, L H Miller, M F Good
Journal: The Journal of Immunology
J Immunol (1994) 153 (5): 2082–2092.
https://doi.org/10.4049/jimmunol.153.5.2082
Published: 01 September 1994
View article titled, Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites.
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Journal Articles

Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.

M Shirai, C D Pendleton, J Ahlers, T Takeshita, M Newman, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1994) 152 (2): 549–556.
https://doi.org/10.4049/jimmunol.152.2.549
Published: 15 January 1994
View article titled, Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs.
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Journal Articles

Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides.

S Kozlowski, M Corr, M Shirai, L F Boyd, C D Pendleton, J A Berzofsky, D H Margulies
Journal: The Journal of Immunology
J Immunol (1993) 151 (8): 4033–4044.
https://doi.org/10.4049/jimmunol.151.8.4033
Published: 15 October 1993
View article titled, Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides.
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Journal Articles

The role of CD4+ T cells in immunity to malaria sporozoites.

W R Weiss, M Sedegah, J A Berzofsky, S L Hoffman
Journal: The Journal of Immunology
J Immunol (1993) 151 (5): 2690–2698.
https://doi.org/10.4049/jimmunol.151.5.2690
Published: 01 September 1993
View article titled, The role of CD4+ T cells in immunity to malaria sporozoites.
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Journal Articles

Preferential V beta usage by cytotoxic T cells cross-reactive between two epitopes of HIV-1 gp160 and degenerate in class I MHC restriction.

M Shirai, M S Vacchio, R J Hodes, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1993) 151 (4): 2283–2295.
https://doi.org/10.4049/jimmunol.151.4.2283
Published: 15 August 1993
View article titled, Preferential V beta usage by cytotoxic T cells cross-reactive between two epitopes of HIV-1 gp160 and degenerate in class I MHC restriction.
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Journal Articles

Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.

J D Ahlers, C D Pendleton, N Dunlop, A Minassian, P L Nara, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1993) 150 (12): 5647–5665.
https://doi.org/10.4049/jimmunol.150.12.5647
Published: 15 June 1993
View article titled, Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.
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Journal Articles

The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition.

W H Boehncke, T Takeshita, C D Pendleton, R A Houghten, S Sadegh-Nasseri, L Racioppi, J A Berzofsky, R N Germain
Journal: The Journal of Immunology
J Immunol (1993) 150 (2): 331–341.
https://doi.org/10.4049/jimmunol.150.2.331
Published: 15 January 1993
View article titled, The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition.
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Journal Articles

A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei.

W R Weiss, J A Berzofsky, R A Houghten, M Sedegah, M Hollindale, S L Hoffman
Journal: The Journal of Immunology
J Immunol (1992) 149 (6): 2103–2109.
https://doi.org/10.4049/jimmunol.149.6.2103
Published: 15 September 1992
View article titled, A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei.
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Journal Articles

Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1.

A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, S H Hughes, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1992) 149 (4): 1311–1318.
https://doi.org/10.4049/jimmunol.149.4.1311
Published: 15 August 1992
View article titled, Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1.
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Journal Articles

Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.

M C Kullberg, E J Pearce, S E Hieny, A Sher, J A Berzofsky
Journal: The Journal of Immunology
J Immunol (1992) 148 (10): 3264–3270.
https://doi.org/10.4049/jimmunol.148.10.3264
Published: 15 May 1992
View article titled, Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.
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