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J A Bluestone
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Journal Articles

Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation.

M G Levisetti, P A Padrid, G L Szot, N Mittal, S M Meehan, C L Wardrip, G S Gray, D S Bruce, J R Thistlethwaite, Jr, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 159 (11): 5187–5191.
https://doi.org/10.4049/jimmunol.159.11.5187
Published: 01 December 1997
View article titled, Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation.
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Journal Articles

Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation.

K C Herold, J Lu, I Rulifson, V Vezys, D Taub, M J Grusby, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 159 (9): 4150–4153.
https://doi.org/10.4049/jimmunol.159.9.4150
Published: 01 November 1997
View article titled, Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation.
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Journal Articles

Selective expansion of Vgamma2-Vdelta7 TCR gammadelta cells in C57BL/6 mice is postnatal and extrathymic.

A I Sperling, D C Decker, R J DiPaolo, D A Stern, A Shum, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 159 (1): 86–91.
https://doi.org/10.4049/jimmunol.159.1.86
Published: 01 July 1997
View article titled, Selective expansion of Vgamma2-Vdelta7 TCR gammadelta cells in C57BL/6 mice is postnatal and extrathymic.
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Journal Articles

Is CTLA-4 a master switch for peripheral T cell tolerance?

J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 158 (5): 1989–1993.
https://doi.org/10.4049/jimmunol.158.5.1989
Published: 01 March 1997
View article titled, Is CTLA-4 a master switch for peripheral T cell tolerance?
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Journal Articles

Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway.

E S Woodle, D M Smith, J A Bluestone, W M Kirkman, 3rd, D R Green, E W Skowronski
Journal: The Journal of Immunology
J Immunol (1997) 158 (5): 2156–2164.
https://doi.org/10.4049/jimmunol.158.5.2156
Published: 01 March 1997
View article titled, Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway.
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Journal Articles

CD28 costimulation promotes the production of Th2 cytokines.

I C Rulifson, A I Sperling, P E Fields, F W Fitch, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 158 (2): 658–665.
https://doi.org/10.4049/jimmunol.158.2.658
Published: 15 January 1997
View article titled, CD28 costimulation promotes the production of Th2 cytokines.
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Journal Articles

CD28/B7 costimulation regulates autoimmune diabetes induced with multiple low doses of streptozotocin.

K C Herold, V Vezys, A Koons, D Lenschow, C Thompson, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1997) 158 (2): 984–991.
https://doi.org/10.4049/jimmunol.158.2.984
Published: 15 January 1997
View article titled, CD28/B7 costimulation regulates autoimmune diabetes induced with multiple low doses of streptozotocin.
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Journal Articles

CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation.

A I Sperling, J A Auger, B D Ehst, I C Rulifson, C B Thompson, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1996) 157 (9): 3909–3917.
https://doi.org/10.4049/jimmunol.157.9.3909
Published: 01 November 1996
View article titled, CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation.
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Journal Articles

TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen.

R Khattri, A I Sperling, D Qian, F W Fitch, E W Shores, P E Love, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1996) 157 (6): 2320–2327.
https://doi.org/10.4049/jimmunol.157.6.2320
Published: 15 September 1996
View article titled, TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen.
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Journal Articles

CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance.

T L Walunas, A I Sperling, R Khattri, C B Thompson, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1996) 156 (3): 1006–1013.
https://doi.org/10.4049/jimmunol.156.3.1006
Published: 01 February 1996
View article titled, CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance.
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Journal Articles

IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.

H Nishimura, K Hiromatsu, N Kobayashi, K H Grabstein, R Paxton, K Sugamura, J A Bluestone, Y Yoshikai
Journal: The Journal of Immunology
J Immunol (1996) 156 (2): 663–669.
https://doi.org/10.4049/jimmunol.156.2.663
Published: 15 January 1996
View article titled, IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.
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Journal Articles

Functional expression and recognition of nonclassical MHC class I T10b is not peptide-dependent.

A Kaliyaperumal, R Falchetto, A Cox, R Dick, 2nd, J Shabanowitz, Y H Chien, L Matis, D F Hunt, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1995) 155 (5): 2379–2386.
https://doi.org/10.4049/jimmunol.155.5.2379
Published: 01 September 1995
View article titled, Functional expression and recognition of nonclassical MHC class I T10b is not peptide-dependent.
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Journal Articles

Ly-6C is a marker of memory CD8+ T cells.

T L Walunas, D S Bruce, L Dustin, D Y Loh, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1995) 155 (4): 1873–1883.
https://doi.org/10.4049/jimmunol.155.4.1873
Published: 15 August 1995
View article titled, Ly-6C is a marker of memory CD8+ T cells.
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Journal Articles

An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.

M L Alegre, J Y Tso, H A Sattar, J Smith, F Desalle, M Cole, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1995) 155 (3): 1544–1555.
https://doi.org/10.4049/jimmunol.155.3.1544
Published: 01 August 1995
View article titled, An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.
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Journal Articles

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

E R Kearney, T L Walunas, R W Karr, P A Morton, D Y Loh, J A Bluestone, M K Jenkins
Journal: The Journal of Immunology
J Immunol (1995) 155 (3): 1032–1036.
https://doi.org/10.4049/jimmunol.155.3.1032
Published: 01 August 1995
View article titled, Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.
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Journal Articles

Two waves of gamma delta T cells expressing different V delta genes are recruited into schistosome-induced liver granulomas.

M Sandor, A I Sperling, G A Cook, J V Weinstock, R G Lynch, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1995) 155 (1): 275–284.
https://doi.org/10.4049/jimmunol.155.1.275
Published: 01 July 1995
View article titled, Two waves of gamma delta T cells expressing different V delta genes are recruited into schistosome-induced liver granulomas.
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Journal Articles

Insight into the mechanism of TCR-V beta 8+/CD8+ T cell-mediated MOPC-315 tumor eradication.

M B Mokyr, A Prokhorova, M Rubin, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1994) 153 (7): 3123–3134.
https://doi.org/10.4049/jimmunol.153.7.3123
Published: 01 October 1994
View article titled, Insight into the mechanism of TCR-V beta 8+/CD8+ T cell-mediated MOPC-315 tumor eradication.
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Journal Articles

Severe combined immunodeficient mice engrafted with human splenocytes have functional human T cells and reject human allografts.

M L Alegre, L J Peterson, D R Jeyarajah, M Weiser, J A Bluestone, J R Thistlethwaite
Journal: The Journal of Immunology
J Immunol (1994) 153 (6): 2738–2749.
https://doi.org/10.4049/jimmunol.153.6.2738
Published: 15 September 1994
View article titled, Severe combined immunodeficient mice engrafted with human splenocytes have functional human T cells and reject human allografts.
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Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen.

D J Lenschow, A I Sperling, M P Cooke, G Freeman, L Rhee, D C Decker, G Gray, L M Nadler, C C Goodnow, J A Bluestone
Journal: The Journal of Immunology
J Immunol (1994) 153 (5): 1990–1997.
https://doi.org/10.4049/jimmunol.153.5.1990
Published: 01 September 1994
View article titled, Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen.
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Journal Articles

Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules.

D M Smith, J A Bluestone, D R Jeyarajah, M H Newberg, V H Engelhard, J R Thistlethwaite, Jr, E S Woodle
Journal: The Journal of Immunology
J Immunol (1994) 153 (3): 1054–1067.
https://doi.org/10.4049/jimmunol.153.3.1054
Published: 01 August 1994
View article titled, Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules.
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