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CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8⁺ T cells

N. Scholler, M. Hayden-Ledbetter, K.-E. Hellström, I. Hellström, J. A. Ledbetter

J Immunol (2009) 182 (3): 1772–1773.

https://doi.org/10.4049/jimmunol.182.3.1772-a

Published: 01 February 2009

View article titled, CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8<sup>+</sup> T cells

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HLA-DR-triggered inhibition of hemopoiesis involves Fas/Fas ligand interactions and is prevented by c-kit ligand.

J W Lee, G M Gersuk, P A Kiener, C Beckham, J A Ledbetter, H J Deeg

J Immunol (1997) 159 (7): 3211–3219.

https://doi.org/10.4049/jimmunol.159.7.3211

Published: 01 October 1997

View article titled, HLA-DR-triggered inhibition of hemopoiesis involves Fas/Fas ligand interactions and is prevented by c-kit ligand.

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Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation.

P A Kiener, P M Davis, B M Rankin, S J Klebanoff, J A Ledbetter, G C Starling, W C Liles

J Immunol (1997) 159 (4): 1594–1598.

https://doi.org/10.4049/jimmunol.159.4.1594

Published: 15 August 1997

View article titled, Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation.

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Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.

N V Sherbina, P S Linsley, S Myrdal, L S Grosmaire, J A Ledbetter, G L Schieven

J Immunol (1996) 157 (10): 4390–4398.

https://doi.org/10.4049/jimmunol.157.10.4390

Published: 15 November 1996

View article titled, Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.

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Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.

J A Francisco, P A Kiener, P Moran-Davis, J A Ledbetter, C B Siegall

J Immunol (1996) 157 (4): 1652–1658.

https://doi.org/10.4049/jimmunol.157.4.1652

Published: 15 August 1996

View article titled, Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.

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The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation.

M Inobe, N Aoki, P S Linsley, J A Ledbetter, R Abe, M Murakami, T Uede

J Immunol (1996) 157 (2): 582–588.

https://doi.org/10.4049/jimmunol.157.2.582

Published: 15 July 1996

View article titled, The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation.

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Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid.

P M Dubois, D Palmer, M L Webb, J A Ledbetter, R A Shapiro

J Immunol (1996) 156 (4): 1356–1361.

https://doi.org/10.4049/jimmunol.156.4.1356

Published: 15 February 1996

View article titled, Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid.

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Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes.

W C Liles, J A Ledbetter, A W Waltersdorph, S J Klebanoff

J Immunol (1995) 155 (4): 2175–2184.

https://doi.org/10.4049/jimmunol.155.4.2175

Published: 15 August 1995

View article titled, Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes.

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CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses.

H Ohnishi, J A Ledbetter, S B Kanner, P S Linsley, T Tanaka, A M Geller, M Kotb

J Immunol (1995) 154 (7): 3180–3193.

https://doi.org/10.4049/jimmunol.154.7.3180

Published: 01 April 1995

View article titled, CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses.

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Differential regulation of proto-oncogenes c-jun and c-fos in T lymphocytes activated through CD28.

G S Chatta, A G Spies, S Chang, G J Mize, P S Linsley, J A Ledbetter, D R Morris

J Immunol (1994) 153 (12): 5393–5401.

https://doi.org/10.4049/jimmunol.153.12.5393

Published: 15 December 1994

View article titled, Differential regulation of proto-oncogenes c-jun and c-fos in T lymphocytes activated through CD28.

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Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction.

E Flescher, J A Ledbetter, G L Schieven, N Vela-Roch, D Fossum, H Dang, N Ogawa, N Talal

J Immunol (1994) 153 (11): 4880–4889.

https://doi.org/10.4049/jimmunol.153.11.4880

Published: 01 December 1994

View article titled, Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction.

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Signaling events during helper T cell-dependent B cell activation. I. Analysis of the signal transduction pathways triggered by activated helper T cell in resting B cells.

L S Marshall, D M Shepherd, J A Ledbetter, A Aruffo, R J Noelle

J Immunol (1994) 152 (10): 4816–4825.

https://doi.org/10.4049/jimmunol.152.10.4816

Published: 15 May 1994

View article titled, Signaling events during helper T cell-dependent B cell activation. I. Analysis of the signal transduction pathways triggered by activated helper T cell in resting B cells.

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Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7.

N K Damle, K Klussman, G Leytze, S Myrdal, A Aruffo, J A Ledbetter, P S Linsley

J Immunol (1994) 152 (6): 2686–2697.

https://doi.org/10.4049/jimmunol.152.6.2686

Published: 15 March 1994

View article titled, Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7.

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Association of tyrosine and serine kinases with the B cell surface antigen CD20. Induction via CD20 of tyrosine phosphorylation and activation of phospholipase C-gamma 1 and PLC phospholipase C-gamma 2.

J P Deans, G L Schieven, G L Shu, M A Valentine, L A Gilliland, A Aruffo, E A Clark, J A Ledbetter

J Immunol (1993) 151 (9): 4494–4504.

https://doi.org/10.4049/jimmunol.151.9.4494

Published: 01 November 1993

View article titled, Association of tyrosine and serine kinases with the B cell surface antigen CD20. Induction via CD20 of tyrosine phosphorylation and activation of phospholipase C-gamma 1 and PLC phospholipase C-gamma 2.

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The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

M Roy, T Waldschmidt, A Aruffo, J A Ledbetter, R J Noelle

J Immunol (1993) 151 (5): 2497–2510.

https://doi.org/10.4049/jimmunol.151.5.2497

Published: 01 September 1993

View article titled, The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

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Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.

N K Damle, K Klussman, G Leytze, A Aruffo, P S Linsley, J A Ledbetter

J Immunol (1993) 151 (5): 2368–2379.

https://doi.org/10.4049/jimmunol.151.5.2368

Published: 01 September 1993

View article titled, Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.

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MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors.

N Odum, S B Kanner, J A Ledbetter, A Svejgaard

J Immunol (1993) 150 (12): 5289–5298.

https://doi.org/10.4049/jimmunol.150.12.5289

Published: 15 June 1993

View article titled, MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors.

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CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling.

P S Linsley, J Bradshaw, M Urnes, L Grosmaire, J A Ledbetter

J Immunol (1993) 150 (8): 3161–3169.

https://doi.org/10.4049/jimmunol.150.8.3161

Published: 15 April 1993

View article titled, CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling.

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Journal Articles

Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells.

S B Kanner, N Odum, L Grosmaire, S Masewicz, A Svejgaard, J A Ledbetter

J Immunol (1992) 149 (11): 3482–3488.

https://doi.org/10.4049/jimmunol.149.11.3482

Published: 01 December 1992

View article titled, Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells.

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B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes.

R Tan, S J Teh, J A Ledbetter, P S Linsley, H S Teh

J Immunol (1992) 149 (10): 3217–3224.

https://doi.org/10.4049/jimmunol.149.10.3217

Published: 15 November 1992

View article titled, B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes.

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NARROW

CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8⁺ T cells

HLA-DR-triggered inhibition of hemopoiesis involves Fas/Fas ligand interactions and is prevented by c-kit ligand.

Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation.

Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.

Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.

The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation.

Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid.

Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes.

CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses.

Differential regulation of proto-oncogenes c-jun and c-fos in T lymphocytes activated through CD28.

Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction.

Signaling events during helper T cell-dependent B cell activation. I. Analysis of the signal transduction pathways triggered by activated helper T cell in resting B cells.

Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7.

Association of tyrosine and serine kinases with the B cell surface antigen CD20. Induction via CD20 of tyrosine phosphorylation and activation of phospholipase C-gamma 1 and PLC phospholipase C-gamma 2.

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.

MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors.

CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling.

Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells.

B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes.

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