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J A Titus
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Journal Articles

CD44 is a cytotoxic triggering molecule on human polymorphonuclear cells.

F Pericle, G Sconocchia, J A Titus, D M Segal
Journal: The Journal of Immunology
J Immunol (1996) 157 (10): 4657–4663.
https://doi.org/10.4049/jimmunol.157.10.4657
Published: 15 November 1996
View article titled, CD44 is a cytotoxic triggering molecule on human polymorphonuclear cells.
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Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

C L Mackall, C V Bare, L A Granger, S O Sharrow, J A Titus, R E Gress
Journal: The Journal of Immunology
J Immunol (1996) 156 (12): 4609–4616.
https://doi.org/10.4049/jimmunol.156.12.4609
Published: 15 June 1996
View article titled, Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.
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Retargeting of CTL by an efficiently refolded bispecific single-chain Fv dimer produced in bacteria.

I Kurucz, J A Titus, C R Jost, C M Jacobus, D M Segal
Journal: The Journal of Immunology
J Immunol (1995) 154 (9): 4576–4582.
https://doi.org/10.4049/jimmunol.154.9.4576
Published: 01 May 1995
View article titled, Retargeting of CTL by an efficiently refolded bispecific single-chain Fv dimer produced in bacteria.
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Journal Articles

CD44 is a cytotoxic triggering molecule in human peripheral blood NK cells.

G Sconocchia, J A Titus, D M Segal
Journal: The Journal of Immunology
J Immunol (1994) 153 (12): 5473–5481.
https://doi.org/10.4049/jimmunol.153.12.5473
Published: 15 December 1994
View article titled, CD44 is a cytotoxic triggering molecule in human peripheral blood NK cells.
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Journal Articles

Redirection of T cell-mediated cytotoxicity by a recombinant single-chain Fv molecule.

A J George, J A Titus, C R Jost, I Kurucz, P Perez, S M Andrew, P J Nicholls, J S Huston, D M Segal
Journal: The Journal of Immunology
J Immunol (1994) 152 (4): 1802–1811.
https://doi.org/10.4049/jimmunol.152.4.1802
Published: 15 February 1994
View article titled, Redirection of T cell-mediated cytotoxicity by a recombinant single-chain Fv molecule.
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Journal Articles

Human peripheral blood lymphocytes targeted with bispecific antibodies release cytokines that are essential for inhibiting tumor growth.

J H Qian, J A Titus, S M Andrew, D Mezzanzanica, M A Garrido, J R Wunderlich, D M Segal
Journal: The Journal of Immunology
J Immunol (1991) 146 (9): 3250–3256.
https://doi.org/10.4049/jimmunol.146.9.3250
Published: 01 May 1991
View article titled, Human peripheral blood lymphocytes targeted with bispecific antibodies release cytokines that are essential for inhibiting tumor growth.
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Journal Articles

Targeted cytotoxic cells in human peripheral blood lymphocytes.

M A Garrido, P Perez, J A Titus, M J Valdayo, D F Winkler, S A Barbieri, J R Wunderlich, D M Segal
Journal: The Journal of Immunology
J Immunol (1990) 144 (8): 2891–2898.
https://doi.org/10.4049/jimmunol.144.8.2891
Published: 15 April 1990
View article titled, Targeted cytotoxic cells in human peripheral blood lymphocytes.
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Journal Articles

Human K/natural killer cells targeted with hetero-cross-linked antibodies specifically lyse tumor cells in vitro and prevent tumor growth in vivo.

J A Titus, P Perez, A Kaubisch, M A Garrido, D M Segal
Journal: The Journal of Immunology
J Immunol (1987) 139 (9): 3153–3158.
https://doi.org/10.4049/jimmunol.139.9.3153
Published: 01 November 1987
View article titled, Human K/natural killer cells targeted with hetero-cross-linked antibodies specifically lyse tumor cells in vitro and prevent tumor growth in vivo.
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Journal Articles

Human T cells targeted with anti-T3 cross-linked to antitumor antibody prevent tumor growth in nude mice.

J A Titus, M A Garrido, T T Hecht, D F Winkler, J R Wunderlich, D M Segal
Journal: The Journal of Immunology
J Immunol (1987) 138 (11): 4018–4022.
https://doi.org/10.4049/jimmunol.138.11.4018
Published: 01 June 1987
View article titled, Human T cells targeted with anti-T3 cross-linked to antitumor antibody prevent tumor growth in nude mice.
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Journal Articles

Specific lysis of human tumor cells by T cells coated with anti-T3 cross-linked to anti-tumor antibody.

P Perez, J A Titus, M T Lotze, F Cuttitta, D L Longo, E S Groves, H Rabin, P J Durda, D M Segal
Journal: The Journal of Immunology
J Immunol (1986) 137 (7): 2069–2072.
https://doi.org/10.4049/jimmunol.137.7.2069
Published: 01 October 1986
View article titled, Specific lysis of human tumor cells by T cells coated with anti-T3 cross-linked to anti-tumor antibody.
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Journal Articles

In vivo treatment with monoclonal anti-I-A antibodies: disappearance of splenic antigen-presenting cell function concomitant with modulation of splenic cell surface I-A and I-E antigens.

A M Kruisbeek, J A Titus, D A Stephany, B L Gause, D L Longo
Journal: The Journal of Immunology
J Immunol (1985) 134 (6): 3605–3614.
https://doi.org/10.4049/jimmunol.134.6.3605
Published: 01 June 1985
View article titled, In vivo treatment with monoclonal anti-I-A antibodies: disappearance of splenic antigen-presenting cell function concomitant with modulation of splenic cell surface I-A and I-E antigens.
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Journal Articles

Characterization of murine lymphocyte IgE receptors by flow microfluorometry.

I M Katona, J F Urban, Jr, J A Titus, D A Stephany, D M Segal, F D Finkelman
Journal: The Journal of Immunology
J Immunol (1984) 133 (3): 1521–1528.
https://doi.org/10.4049/jimmunol.133.3.1521
Published: 01 September 1984
View article titled, Characterization of murine lymphocyte IgE receptors by flow microfluorometry.
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Journal Articles

Quantitative analysis of Fc gamma receptors on murine spleen cell populations by using dual parameter flow cytometry.

J A Titus, F D Finkelman, D A Stephany, J F Jones, D M Segal
Journal: The Journal of Immunology
J Immunol (1984) 133 (2): 556–561.
https://doi.org/10.4049/jimmunol.133.2.556
Published: 01 August 1984
View article titled, Quantitative analysis of Fc gamma receptors on murine spleen cell populations by using dual parameter flow cytometry.
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Journal Articles

Analysis of Fc (IgG) receptors on human peripheral blood leukocytes by dual fluorescence flow microfluorometry. II. Quantitation of receptors on cells that express the OKM1, OKT3, OKT4, and OKT8 antigens.

J A Titus, S O Sharrow, D M Segal
Journal: The Journal of Immunology
J Immunol (1983) 130 (3): 1152–1158.
https://doi.org/10.4049/jimmunol.130.3.1152
Published: 01 March 1983
View article titled, Analysis of Fc (IgG) receptors on human peripheral blood leukocytes by dual fluorescence flow microfluorometry. II. Quantitation of receptors on cells that express the OKM1, OKT3, OKT4, and OKT8 antigens.
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Journal Articles

The ontogeny and distribution of B cells in normal and mutant immune-defective CBA/N mice: two-parameter analysis of surface IgM and IgD.

I Scher, J A Titus, F D Finkelman
Journal: The Journal of Immunology
J Immunol (1983) 130 (2): 619–625.
https://doi.org/10.4049/jimmunol.130.2.619
Published: 01 February 1983
View article titled, The ontogeny and distribution of B cells in normal and mutant immune-defective CBA/N mice: two-parameter analysis of surface IgM and IgD.
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The FcR-mediated endocytosis of model immune complexes by cells from the P388D1 mouse macrophage line. II. The role of ligand-induced self-aggregation in promoting internalization.

D M Segal, J A Titus, S K Dower
Journal: The Journal of Immunology
J Immunol (1983) 130 (1): 138–144.
https://doi.org/10.4049/jimmunol.130.1.138
Published: 01 January 1983
View article titled, The FcR-mediated endocytosis of model immune complexes by cells from the P388D1 mouse macrophage line. II. The role of ligand-induced self-aggregation in promoting internalization.
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Journal Articles

The FcR-mediated endocytosis of model immune complexes by cells from the P338D1 mouse macrophage line. I. Internalization of small, nonaggregating oligomers of IgG.

D M Segal, S K Dower, J A Titus
Journal: The Journal of Immunology
J Immunol (1983) 130 (1): 130–137.
https://doi.org/10.4049/jimmunol.130.1.130
Published: 01 January 1983
View article titled, The FcR-mediated endocytosis of model immune complexes by cells from the P338D1 mouse macrophage line. I. Internalization of small, nonaggregating oligomers of IgG.
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Antibody-dependent, cell-mediated cytolysis (ADCC) with antibody-coated effectors: rat and human effectors versus tumor targets.

J F Jones, J A Titus, D M Segal
Journal: The Journal of Immunology
J Immunol (1981) 126 (6): 2457–2460.
https://doi.org/10.4049/jimmunol.126.6.2457
Published: 01 June 1981
View article titled, Antibody-dependent, cell-mediated cytolysis (ADCC) with antibody-coated effectors: rat and human effectors versus tumor targets.
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