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J J O'Shea
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Journal Articles

Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.

S S Cho, C M Bacon, C Sudarshan, R C Rees, D Finbloom, R Pine, J J O'Shea
Journal: The Journal of Immunology
J Immunol (1996) 157 (11): 4781–4789.
https://doi.org/10.4049/jimmunol.157.11.4781
Published: 01 December 1996
View article titled, Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.
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Regulation of JAK3 expression and activation in human B cells and B cell malignancies.

P J Tortolani, B K Lal, A Riva, J A Johnston, Y Q Chen, G H Reaman, M Beckwith, D Longo, J R Ortaldo, K Bhatia, I McGrath, J Kehrl, J Tuscano, D W McVicar, J J O'Shea
Journal: The Journal of Immunology
J Immunol (1995) 155 (11): 5220–5226.
https://doi.org/10.4049/jimmunol.155.11.5220
Published: 01 December 1995
View article titled, Regulation of JAK3 expression and activation in human B cells and B cell malignancies.
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Journal Articles

Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID).

W J Murphy, S K Durum, M R Anver, D K Ferris, D W McVicar, J J O'Shea, S K Ruscetti, M R Smith, H A Young, D L Longo
Journal: The Journal of Immunology
J Immunol (1994) 153 (3): 1004–1014.
https://doi.org/10.4049/jimmunol.153.3.1004
Published: 01 August 1994
View article titled, Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID).
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Journal Articles

Expression of v-src in T cells correlates with nuclear expression of NF-kappa B.

D M Eicher, T H Tan, N R Rice, J J O'Shea, I C Kennedy
Journal: The Journal of Immunology
J Immunol (1994) 152 (6): 2710–2719.
https://doi.org/10.4049/jimmunol.152.6.2710
Published: 15 March 1994
View article titled, Expression of v-src in T cells correlates with nuclear expression of NF-kappa B.
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Journal Articles

A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A.

J J O'Shea, D W McVicar, D B Kuhns, J R Ortaldo
Journal: The Journal of Immunology
J Immunol (1992) 148 (8): 2497–2502.
https://doi.org/10.4049/jimmunol.148.8.2497
Published: 15 April 1992
View article titled, A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A.
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Journal Articles

Characterization of the family of dimers associated with Fc receptors (Fc epsilon RI and Fc gamma RIII).

O Letourneur, I C Kennedy, A T Brini, J R Ortaldo, J J O'Shea, J P Kinet
Journal: The Journal of Immunology
J Immunol (1991) 147 (8): 2652–2656.
https://doi.org/10.4049/jimmunol.147.8.2652
Published: 15 October 1991
View article titled, Characterization of the family of dimers associated with Fc receptors (Fc epsilon RI and Fc gamma RIII).
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Journal Articles

Mechanistic studies of transforming growth factor-beta inhibition of IL-2-dependent activation of CD3- large granular lymphocyte functions. Regulation of IL-2R beta (p75) signal transduction.

J R Ortaldo, A T Mason, J J O'Shea, M J Smyth, L A Falk, I C Kennedy, D L Longo, F W Ruscetti
Journal: The Journal of Immunology
J Immunol (1991) 146 (11): 3791–3798.
https://doi.org/10.4049/jimmunol.146.11.3791
Published: 01 June 1991
View article titled, Mechanistic studies of transforming growth factor-beta inhibition of IL-2-dependent activation of CD3- large granular lymphocyte functions. Regulation of IL-2R beta (p75) signal transduction.
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Journal Articles

Aluminum fluoride induces phosphatidylinositol turnover, elevation of cytoplasmic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells.

J J O'Shea, K B Urdahl, H T Luong, T M Chused, L E Samelson, R D Klausner
Journal: The Journal of Immunology
J Immunol (1987) 139 (10): 3463–3469.
https://doi.org/10.4049/jimmunol.139.10.3463
Published: 15 November 1987
View article titled, Aluminum fluoride induces phosphatidylinositol turnover, elevation of cytoplasmic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells.
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Journal Articles

T cell antigen receptor phosphorylation induced by an anti-receptor antibody.

L E Samelson, J J O'Shea, H Luong, P Ross, K B Urdahl, R D Klausner, J Bluestone
Journal: The Journal of Immunology
J Immunol (1987) 139 (8): 2708–2714.
https://doi.org/10.4049/jimmunol.139.8.2708
Published: 15 October 1987
View article titled, T cell antigen receptor phosphorylation induced by an anti-receptor antibody.
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Journal Articles

Characterization of the C3 receptor induced by herpes simplex virus type 1 infection of human epidermal, endothelial, and A431 cells.

Y Kubota, T A Gaither, J Cason, J J O'Shea, T J Lawley
Journal: The Journal of Immunology
J Immunol (1987) 138 (4): 1137–1142.
https://doi.org/10.4049/jimmunol.138.4.1137
Published: 15 February 1987
View article titled, Characterization of the C3 receptor induced by herpes simplex virus type 1 infection of human epidermal, endothelial, and A431 cells.
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Journal Articles

Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors.

J E Edwards, Jr, T A Gaither, J J O'Shea, D Rotrosen, T J Lawley, S A Wright, M M Frank, I Green
Journal: The Journal of Immunology
J Immunol (1986) 137 (11): 3577–3583.
https://doi.org/10.4049/jimmunol.137.11.3577
Published: 01 December 1986
View article titled, Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors.
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Journal Articles

Identification and characterization of the phosphatidylinositol kinase in membranes of murine T lymphocytes.

J J O'Shea, J B Harford, R D Klausner
Journal: The Journal of Immunology
J Immunol (1986) 137 (3): 971–976.
https://doi.org/10.4049/jimmunol.137.3.971
Published: 01 August 1986
View article titled, Identification and characterization of the phosphatidylinositol kinase in membranes of murine T lymphocytes.
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Journal Articles

Activation of the C3b receptor: effect of diacylglycerols and calcium mobilization.

J J O'Shea, S A Siwik, T A Gaither, M M Frank
Journal: The Journal of Immunology
J Immunol (1985) 135 (5): 3381–3387.
https://doi.org/10.4049/jimmunol.135.5.3381
Published: 01 November 1985
View article titled, Activation of the C3b receptor: effect of diacylglycerols and calcium mobilization.
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Journal Articles

Fibronectin-enhanced phagocytosis of an alternative pathway activator by human culture-derived macrophages is mediated by the C4b/C3b complement receptor (CR1).

J F Bohnsack, J J O'Shea, T Takahashi, E J Brown
Journal: The Journal of Immunology
J Immunol (1985) 135 (4): 2680–2686.
https://doi.org/10.4049/jimmunol.135.4.2680
Published: 01 October 1985
View article titled, Fibronectin-enhanced phagocytosis of an alternative pathway activator by human culture-derived macrophages is mediated by the C4b/C3b complement receptor (CR1).
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Journal Articles

Calcium requirements for increased complement receptor expression during neutrophil activation.

M Berger, D L Birx, E M Wetzler, J J O'Shea, E J Brown, A S Cross
Journal: The Journal of Immunology
J Immunol (1985) 135 (2): 1342–1348.
https://doi.org/10.4049/jimmunol.135.2.1342
Published: 01 August 1985
View article titled, Calcium requirements for increased complement receptor expression during neutrophil activation.
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Journal Articles

Tumor-promoting phorbol esters induce rapid internalization of the C3b receptor via a cytoskeleton-dependent mechanism.

J J O'Shea, E J Brown, T A Gaither, T Takahashi, M M Frank
Journal: The Journal of Immunology
J Immunol (1985) 135 (2): 1325–1330.
https://doi.org/10.4049/jimmunol.135.2.1325
Published: 01 August 1985
View article titled, Tumor-promoting phorbol esters induce rapid internalization of the C3b receptor via a cytoskeleton-dependent mechanism.
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Journal Articles

Osmotic stress and the freeze-thaw cycle cause shedding of Fc and C3b receptors by human polymorphonuclear leukocytes.

T Takahashi, S Inada, C G Pommier, J J O'Shea, E J Brown
Journal: The Journal of Immunology
J Immunol (1985) 134 (6): 4062–4068.
https://doi.org/10.4049/jimmunol.134.6.4062
Published: 01 June 1985
View article titled, Osmotic stress and the freeze-thaw cycle cause shedding of Fc and C3b receptors by human polymorphonuclear leukocytes.
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Journal Articles

Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.

J J O'Shea, E J Brown, B E Seligmann, J A Metcalf, M M Frank, J I Gallin
Journal: The Journal of Immunology
J Immunol (1985) 134 (4): 2580–2587.
https://doi.org/10.4049/jimmunol.134.4.2580
Published: 01 April 1985
View article titled, Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.
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