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Hepatocytes engulf and rapidly silence coxsackievirus, protecting the host against systemic viral pathology

Taishi Kimura, Claudia T Flynn, J Lindsay Whitton

J Immunol (2020) 204 (1_Supplement): 248.3.

https://doi.org/10.4049/jimmunol.204.Supp.248.3

Published: 01 May 2020

View article titled, Hepatocytes engulf and rapidly silence coxsackievirus, protecting the host against systemic viral pathology

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Journal Articles

TCR-independent suppression of IFNγ production in vivo (VIR1P.1156)

Martin Hosking, Claudia Flynn, J Lindsay Whitton

J Immunol (2015) 194 (1_Supplement): 74.33.

https://doi.org/10.4049/jimmunol.194.Supp.74.33

Published: 01 May 2015

View article titled, TCR-independent suppression of IFNγ production in vivo (VIR1P.1156)

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Antigen-Specific Naive CD8⁺ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect

Martin P. Hosking, Claudia T. Flynn, J. Lindsay Whitton

J Immunol (2014) 193 (4): 1873–1885.

https://doi.org/10.4049/jimmunol.1400348

Published: 15 August 2014

View article titled, Antigen-Specific Naive CD8+ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect

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Differential T Cell Responses to Residual Viral Antigen Prolong CD4⁺ T Cell Contraction following the Resolution of Infection

Ichiro Misumi, Mehrdad Alirezaei, Boreth Eam, Maureen A. Su, J. Lindsay Whitton, Jason K. Whitmire

J Immunol (2013) 191 (11): 5655–5668.

https://doi.org/10.4049/jimmunol.1301215

Published: 01 December 2013

View article titled, Differential T Cell Responses to Residual Viral Antigen Prolong CD4+ T Cell Contraction following the Resolution of Infection

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Includes: Supplementary data

Journal Articles

CD8⁺ Memory T Cells Appear Exhausted within Hours of Acute Virus Infection

Martin P. Hosking, Claudia T. Flynn, Jason Botten, J. Lindsay Whitton

J Immunol (2013) 191 (8): 4211–4222.

https://doi.org/10.4049/jimmunol.1300920

Published: 15 October 2013

View article titled, CD8+ Memory T Cells Appear Exhausted within Hours of Acute Virus Infection

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Journal Articles

Coxsackievirus B3 has profoundly different inhibitory effects on the MHC class I and class II antigen presentation pathways (131.2)

Christopher C Kemball, Stephanie Harkins, Jason K Whitmire, Ralph Feuer, Claudia T Flynn, J Lindsay Whitton

J Immunol (2009) 182 (1_Supplement): 131.2.

https://doi.org/10.4049/jimmunol.182.Supp.131.2

Published: 01 April 2009

View article titled, Coxsackievirus B3 has profoundly different inhibitory effects on the MHC class I and class II antigen presentation pathways (131.2)

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Journal Articles

Increasing the CD4⁺ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality

Jason K. Whitmire, Nicola Benning, Boreth Eam, J. Lindsay Whitton

J Immunol (2008) 180 (10): 6777–6785.

https://doi.org/10.4049/jimmunol.180.10.6777

Published: 15 May 2008

View article titled, Increasing the CD4+ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality

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Journal Articles

Direct Interferon-γ Signaling Dramatically Enhances CD4⁺ and CD8⁺ T Cell Memory

Jason K. Whitmire, Boreth Eam, Nicola Benning, J. Lindsay Whitton

J Immunol (2007) 179 (2): 1190–1197.

https://doi.org/10.4049/jimmunol.179.2.1190

Published: 15 July 2007

View article titled, Direct Interferon-γ Signaling Dramatically Enhances CD4+ and CD8+ T Cell Memory

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Journal Articles

Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4⁺ T Cells

Jason K. Whitmire, Nicola Benning, J. Lindsay Whitton

J Immunol (2006) 176 (5): 3028–3036.

https://doi.org/10.4049/jimmunol.176.5.3028

Published: 01 March 2006

View article titled, Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4+ T Cells

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Journal Articles

Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4⁺ T Cell Responses

Jason K. Whitmire, Nicola Benning, J. Lindsay Whitton

J Immunol (2005) 175 (9): 5624–5628.

https://doi.org/10.4049/jimmunol.175.9.5624

Published: 01 November 2005

View article titled, Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4+ T Cell Responses

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Journal Articles

Immunoproteasome-Deficient Mice Mount Largely Normal CD8⁺ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination

Alexander K. Nussbaum, Maria P. Rodriguez-Carreno, Nicola Benning, Jason Botten, J. Lindsay Whitton

J Immunol (2005) 175 (2): 1153–1160.

https://doi.org/10.4049/jimmunol.175.2.1153

Published: 15 July 2005

View article titled, Immunoproteasome-Deficient Mice Mount Largely Normal CD8+ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination

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Journal Articles

Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8⁺ T Cells during Primary and Secondary Viral Infections

Fei Liu, J. Lindsay Whitton

J Immunol (2005) 174 (10): 5936–5940.

https://doi.org/10.4049/jimmunol.174.10.5936

Published: 15 May 2005

View article titled, Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8+ T Cells during Primary and Secondary Viral Infections

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Journal Articles

The Contraction Phase of Virus-Specific CD8⁺ T Cells Is Unaffected by a Pan-Caspase Inhibitor

Alexander K. Nussbaum, J. Lindsay Whitton

J Immunol (2004) 173 (11): 6611–6618.

https://doi.org/10.4049/jimmunol.173.11.6611

Published: 01 December 2004

View article titled, The Contraction Phase of Virus-Specific CD8+ T Cells Is Unaffected by a Pan-Caspase Inhibitor

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Journal Articles

The Rapidity with Which Virus-Specific CD8⁺ T Cells Initiate IFN-γ Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance

Fei Liu, J. Lindsay Whitton, Mark K. Slifka

J Immunol (2004) 173 (1): 456–462.

https://doi.org/10.4049/jimmunol.173.1.456

Published: 01 July 2004

View article titled, The Rapidity with Which Virus-Specific CD8+ T Cells Initiate IFN-γ Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance

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Journal Articles

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8⁺ and CD4⁺ T Cells

Mark K. Slifka, Robb R. Pagarigan, J. Lindsay Whitton

J Immunol (2004) 172 (11): 7220.

https://doi.org/10.4049/jimmunol.172.11.7220

Published: 01 June 2004

View article titled, NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells

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Journal Articles

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8⁺ and CD4⁺ T Cells

Mark K. Slifka, Robb R. Pagarigan, J. Lindsay Whitton

J Immunol (2000) 164 (4): 2009–2015.

https://doi.org/10.4049/jimmunol.164.4.2009

Published: 15 February 2000

View article titled, NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells

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Journal Articles

Activated and Memory CD8⁺ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers

Mark K. Slifka, J. Lindsay Whitton

J Immunol (2000) 164 (1): 208–216.

https://doi.org/10.4049/jimmunol.164.1.208

Published: 01 January 2000

View article titled, Activated and Memory CD8+ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers

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Journal Articles

Transgenic Expression of IFN-α in the Central Nervous System of Mice Protects Against Lethal Neurotropic Viral Infection but Induces Inflammation and Neurodegeneration

Yvette Akwa, Daniel E. Hassett, Maija-Leena Eloranta, Kristian Sandberg, Eliezer Masliah, Henry Powell, J. Lindsay Whitton, Floyd E. Bloom, Iain L. Campbell

J Immunol (1998) 161 (9): 5016–5026.

https://doi.org/10.4049/jimmunol.161.9.5016

Published: 01 November 1998

View article titled, Transgenic Expression of IFN-α in the Central Nervous System of Mice Protects Against Lethal Neurotropic Viral Infection but Induces Inflammation and Neurodegeneration

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Journal Articles

Acute phase proteins in salmonids: evolutionary analyses and acute phase response.

L E Jensen, M P Hiney, D C Shields, C M Uhlar, A J Lindsay, A S Whitehead

J Immunol (1997) 158 (1): 384–392.

https://doi.org/10.4049/jimmunol.158.1.384

Published: 01 January 1997

View article titled, Acute phase proteins in salmonids: evolutionary analyses and acute phase response.

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Journal Articles

Molecular variation of human major histocompatibility complex DQw3 beta-chains.

A K So, J Lindsay, J Bodmer, J Trowsdale

J Immunol (1987) 139 (10): 3506–3511.

https://doi.org/10.4049/jimmunol.139.10.3506

Published: 15 November 1987

View article titled, Molecular variation of human major histocompatibility complex DQw3 beta-chains.

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NARROW

Hepatocytes engulf and rapidly silence coxsackievirus, protecting the host against systemic viral pathology

TCR-independent suppression of IFNγ production in vivo (VIR1P.1156)

Antigen-Specific Naive CD8⁺ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect

Differential T Cell Responses to Residual Viral Antigen Prolong CD4⁺ T Cell Contraction following the Resolution of Infection

CD8⁺ Memory T Cells Appear Exhausted within Hours of Acute Virus Infection

Coxsackievirus B3 has profoundly different inhibitory effects on the MHC class I and class II antigen presentation pathways (131.2)

Increasing the CD4⁺ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality

Direct Interferon-γ Signaling Dramatically Enhances CD4⁺ and CD8⁺ T Cell Memory

Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4⁺ T Cells

Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4⁺ T Cell Responses

Immunoproteasome-Deficient Mice Mount Largely Normal CD8⁺ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination

Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8⁺ T Cells during Primary and Secondary Viral Infections

The Contraction Phase of Virus-Specific CD8⁺ T Cells Is Unaffected by a Pan-Caspase Inhibitor

The Rapidity with Which Virus-Specific CD8⁺ T Cells Initiate IFN-γ Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8⁺ and CD4⁺ T Cells

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8⁺ and CD4⁺ T Cells

Activated and Memory CD8⁺ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers

Transgenic Expression of IFN-α in the Central Nervous System of Mice Protects Against Lethal Neurotropic Viral Infection but Induces Inflammation and Neurodegeneration

Acute phase proteins in salmonids: evolutionary analyses and acute phase response.

Molecular variation of human major histocompatibility complex DQw3 beta-chains.

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