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J. H. Frederik Falkenburg
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Journal Articles

Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope

Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud de Ru, Peter A. van Veelen, Jamie Rossjohn, Stephanie Gras, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk
Journal: The Journal of Immunology
J Immunol (2022) 208 (8): 1851–1856.
https://doi.org/10.4049/jimmunol.2101208
Published: 15 April 2022
View articletitled, Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope
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Includes: Supplementary data
Journal Articles

Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies

Peter van Balen, Michel G. D. Kester, Wendy de Klerk, Pietro Crivello, Esteban Arrieta-Bolaños, Arnoud H. de Ru, Inge Jedema, Yassene Mohammed, Mirjam H. M. Heemskerk, Katharina Fleischhauer, Peter A. van Veelen, J. H. Frederik Falkenburg
Journal: The Journal of Immunology
J Immunol (2020) 204 (12): 3273–3282.
https://doi.org/10.4049/jimmunol.2000192
Published: 15 June 2020
View articletitled, Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies
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Includes: Supplementary data
Journal Articles

Multiple Knockout of Classical HLA Class II β-Chains by CRISPR/Cas9 Genome Editing Driven by a Single Guide RNA

Pietro Crivello, Müberra Ahci, Fabienne Maaßen, Natalie Wossidlo, Esteban Arrieta-Bolaños, Andreas Heinold, Vinzenz Lange, J. H. Frederik Falkenburg, Peter A. Horn, Katharina Fleischhauer, Stefan Heinrichs
Journal: The Journal of Immunology
J Immunol (2019) 202 (6): 1895–1903.
https://doi.org/10.4049/jimmunol.1800257
Published: 15 March 2019
View articletitled, Multiple Knockout of Classical HLA Class II β-Chains by CRISPR/Cas9 Genome Editing Driven by a Single Guide RNA
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Includes: Supplementary data
Journal Articles

High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor−/CD52− T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell–Depleted Allogeneic Stem Cell Transplantation

Floris C. Loeff, J. H. Frederik Falkenburg, Lois Hageman, Wesley Huisman, Sabrina A. J. Veld, H. M. Esther van Egmond, Marian van de Meent, Peter A. von dem Borne, Hendrik Veelken, Constantijn J. M. Halkes, Inge Jedema
Journal: The Journal of Immunology
J Immunol (2018) 200 (6): 2199–2208.
https://doi.org/10.4049/jimmunol.1701018
Published: 15 March 2018
View articletitled, High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor−/CD52− T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell–Depleted Allogeneic Stem Cell Transplantation
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Includes: Supplementary data
Journal Articles

Discovery of T Cell Epitopes Implementing HLA-Peptidomics into a Reverse Immunology Approach

Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Arnoud H. de Ru, Cornelis A. M. van Bergen, Harm Nijveen, Jan W. Drijfhout, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk, Peter A. van Veelen
Journal: The Journal of Immunology
J Immunol (2013) 190 (8): 3869–3877.
https://doi.org/10.4049/jimmunol.1202351
Published: 15 April 2013
View articletitled, Discovery of T Cell Epitopes Implementing HLA-Peptidomics into a Reverse Immunology Approach
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Includes: Supplementary data
Journal Articles

B and T Lymphocyte Attenuator Mediates Inhibition of Tumor-Reactive CD8+ T Cells in Patients After Allogeneic Stem Cell Transplantation

Willemijn Hobo, Wieger J. Norde, Nicolaas Schaap, Hanny Fredrix, Frans Maas, Karen Schellens, J. H. Frederik Falkenburg, Alan J. Korman, Daniel Olive, Robbert van der Voort, Harry Dolstra
Journal: The Journal of Immunology
J Immunol (2012) 189 (1): 39–49.
https://doi.org/10.4049/jimmunol.1102807
Published: 01 July 2012
View articletitled, B and T Lymphocyte Attenuator Mediates Inhibition of Tumor-Reactive CD8+ T Cells in Patients After Allogeneic Stem Cell Transplantation
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Includes: Supplementary data
Journal Articles

Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity

Willem J. J. Falkenburg, J. Joseph Melenhorst, Marian van de Meent, Michel G. D. Kester, Pleun Hombrink, Mirjam H. M. Heemskerk, Renate S. Hagedoorn, Emma Gostick, David A. Price, J. H. Frederik Falkenburg, A. John Barrett, Inge Jedema
Journal: The Journal of Immunology
J Immunol (2011) 187 (5): 2824–2833.
https://doi.org/10.4049/jimmunol.1100852
Published: 01 September 2011
View articletitled, Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity
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Journal Articles

Functional Analysis of Killer Ig-Like Receptor-Expressing Cytomegalovirus-Specific CD8+ T Cells

Lars T. van der Veken, Maria Diez Campelo, Menno A. W. G. van der Hoorn, Renate S. Hagedoorn, H. M. Esther van Egmond, Jeroen van Bergen, Roel Willemze, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk
Journal: The Journal of Immunology
J Immunol (2009) 182 (1): 92–101.
https://doi.org/10.4049/jimmunol.182.1.92
Published: 01 January 2009
View articletitled, Functional Analysis of Killer Ig-Like Receptor-Expressing Cytomegalovirus-Specific CD8+ T Cells
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Journal Articles

αβ T Cell Receptor Transfer to γδ T Cells Generates Functional Effector Cells without Mixed TCR Dimers In Vivo

Lars T. van der Veken, Miriam Coccoris, Erwin Swart, J. H. Frederik Falkenburg, Ton N. Schumacher, Mirjam H. M. Heemskerk
Journal: The Journal of Immunology
J Immunol (2009) 182 (1): 164–170.
https://doi.org/10.4049/jimmunol.182.1.164
Published: 01 January 2009
View articletitled, αβ T Cell Receptor Transfer to γδ T Cells Generates Functional Effector Cells without Mixed TCR Dimers In Vivo
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