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James E. McLaren
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Journal Articles

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells

Benjamin J. Meckiff, Kristin Ladell, James E. McLaren, Gordon B. Ryan, Alison M. Leese, Eddie A. James, David A. Price, Heather M. Long
Journal: The Journal of Immunology
J Immunol (2019) 203 (5): 1276–1287.
https://doi.org/10.4049/jimmunol.1900377
Published: 01 September 2019
View articletitled, Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells
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Includes: Supplementary data
Journal Articles

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

James E. McLaren, Mathew Clement, Morgan Marsden, Kelly L. Miners, Sian Llewellyn-Lacey, Emma J. Grant, Anzelika Rubina, Silvia Gimeno Brias, Emma Gostick, Maria A. Stacey, Selinda J. Orr, Richard J. Stanton, Kristin Ladell, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 943–955.
https://doi.org/10.4049/jimmunol.1701757
Published: 01 February 2019
View articletitled, IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
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Includes: Supplementary data
Journal Articles

Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Linda Wooldridge, David Morgan, James Alexander Pearson, Stephanie Gras, Hugo van den Berg, Anya Lissina, Sian Llewellyn-Lacey, Mark Willis, Tamsin Dockree, James E McLaren, Julia Ekeruche-Makinde, Emma Gostick, Neil Robertson, Jamie Rossjohn, Scott R Burrows, David Price, Susan Wong, Mark Peakman, Ania Skowera, Matthew Clement
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 127.26.
https://doi.org/10.4049/jimmunol.198.Supp.127.26
Published: 01 May 2017
View articletitled, Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation
Add to Citation Manager for Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation
Journal Articles

Determinants of Gliadin-Specific T Cell Selection in Celiac Disease

Jan Petersen, Jeroen van Bergen, Khai Lee Loh, Yvonne Kooy-Winkelaar, Dennis X. Beringer, Allan Thompson, Sjoerd F. Bakker, Chris J. J. Mulder, Kristin Ladell, James E. McLaren, David A. Price, Jamie Rossjohn, Hugh H. Reid, Frits Koning
Journal: The Journal of Immunology
J Immunol (2015) 194 (12): 6112–6122.
https://doi.org/10.4049/jimmunol.1500161
Published: 15 June 2015
View articletitled, Determinants of Gliadin-Specific T Cell Selection in Celiac Disease
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Includes: Supplementary data
Journal Articles

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

Henrik N. Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung’u, Søren Buus, David A. Price, Philip J. Goulder
Journal: The Journal of Immunology
J Immunol (2015) 194 (11): 5329–5345.
https://doi.org/10.4049/jimmunol.1400854
Published: 01 June 2015
View articletitled, CD8+ TCR Bias and Immunodominance in HIV-1 Infection
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Includes: Supplementary data
Journal Articles

ERK Is Integral to the IFN-γ–Mediated Activation of STAT1, the Expression of Key Genes Implicated in Atherosclerosis, and the Uptake of Modified Lipoproteins by Human Macrophages

Na Li, James E. McLaren, Daryn R. Michael, Mathew Clement, Ceri A. Fielding, Dipak P. Ramji
Journal: The Journal of Immunology
J Immunol (2010) 185 (5): 3041–3048.
https://doi.org/10.4049/jimmunol.1000993
Published: 01 September 2010
View articletitled, ERK Is Integral to the IFN-γ–Mediated Activation of STAT1, the Expression of Key Genes Implicated in Atherosclerosis, and the Uptake of Modified Lipoproteins by Human Macrophages
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Includes: Supplementary data
Journal Articles

IL-33 Reduces Macrophage Foam Cell Formation

James E. McLaren, Daryn R. Michael, Rebecca C. Salter, Tim G. Ashlin, Claudia J. Calder, Ashley M. Miller, Foo Y. Liew, Dipak P. Ramji
Journal: The Journal of Immunology
J Immunol (2010) 185 (2): 1222–1229.
https://doi.org/10.4049/jimmunol.1000520
Published: 15 July 2010
View articletitled, IL-33 Reduces Macrophage Foam Cell Formation
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Includes: Supplementary data
Journal Articles

The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro

James E. McLaren, Claudia J. Calder, Brian P. McSharry, Keith Sexton, Rebecca C. Salter, Nishi N. Singh, Gavin W. G. Wilkinson, Eddie C. Y. Wang, Dipak P. Ramji
Journal: The Journal of Immunology
J Immunol (2010) 184 (10): 5827–5834.
https://doi.org/10.4049/jimmunol.0903782
Published: 15 May 2010
View articletitled, The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro
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Add to Citation Manager for The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro
Includes: Supplementary data