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Jean-Pierre Routy
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Journal Articles

RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells

Free
Amélie Cattin, Vanessa Sue Wacleche, Natalia Fonseca Do Rosario, Laurence Raymond Marchand, Jonathan Dias, Annie Gosselin, Eric A. Cohen, Jérôme Estaquier, Nicolas Chomont, Jean-Pierre Routy, Petronela Ancuta
Journal: The Journal of Immunology
J Immunol (2021) 206 (11): 2638–2651.
https://doi.org/10.4049/jimmunol.2001436
Published: 01 June 2021
View articletitled, RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells
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Includes: Supplementary data
Journal Articles

CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir

Free
Noemia S. Lima, Hiroshi Takata, Szu-Han Huang, Alexander Haregot, Julie Mitchell, Stephen Blackmore, Ayanna Garland, Aaron Sy, Pearline Cartwright, Jean-Pierre Routy, Nelson L. Michael, Victor Appay, R. Brad Jones, Lydie Trautmann
Journal: The Journal of Immunology
J Immunol (2020) 205 (3): 699–707.
https://doi.org/10.4049/jimmunol.1900811
Published: 01 August 2020
View articletitled, CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir
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Includes: Supplementary data
Journal Articles

Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells

Free
Filippos Porichis, Meghan G. Hart, Alexandra Massa, Holly L. Everett, Antigoni Morou, Jonathan Richard, Nathalie Brassard, Maxime Veillette, Muska Hassan, Ngoc Le Ly, Jean-Pierre Routy, Gordon J. Freeman, Mathieu Dubé, Andrés Finzi, Daniel E. Kaufmann
Journal: The Journal of Immunology
J Immunol (2018) 201 (3): 971–981.
https://doi.org/10.4049/jimmunol.1701551
Published: 01 August 2018
View articletitled, Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells
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Includes: Supplementary data
Journal Articles

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy

Free
Chao Wang, Maria I. Edilova, Lisa E. Wagar, Shariq Mujib, Meromit Singer, Nicole F. Bernard, Thérèse Croughs, Michael M. Lederman, Irini Sereti, Margaret A. Fischl, Elisabeth Kremmer, Mario Ostrowski, Jean-Pierre Routy, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2018) 200 (2): 558–564.
https://doi.org/10.4049/jimmunol.1601254
Published: 15 January 2018
View articletitled, Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy
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Includes: Supplementary data
Journal Articles

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection

Open Access
Rafael Cubas, Julien van Grevenynghe, Saintedym Wills, Lela Kardava, Brian H. Santich, Clarisa M. Buckner, Roshell Muir, Virginie Tardif, Carmen Nichols, Francesco Procopio, Zhong He, Talibah Metcalf, Khader Ghneim, Michela Locci, Petronella Ancuta, Jean-Pierre Routy, Lydie Trautmann, Yuxing Li, Adrian B. McDermott, Rick A. Koup, Constantinos Petrovas, Steven A. Migueles, Mark Connors, Georgia D. Tomaras, Susan Moir, Shane Crotty, Elias K. Haddad
Journal: The Journal of Immunology
J Immunol (2015) 195 (12): 5625–5636.
https://doi.org/10.4049/jimmunol.1501524
Published: 15 December 2015
View articletitled, Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection
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Includes: Supplementary data
Journal Articles

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

Free
Gaëlle Breton, Nicolas Chomont, Hiroshi Takata, Rémi Fromentin, Jeffrey Ahlers, Abdelali Filali-Mouhim, Catherine Riou, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Bader Yassine-Diab, Rafick-Pierre Sékaly
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2194–2204.
https://doi.org/10.4049/jimmunol.1200646
Published: 01 September 2013
View articletitled, Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection
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Includes: Supplementary data
Journal Articles

Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation

Free
Loury Janbazian, David A. Price, Glenda Canderan, Abdelali Filali-Mouhim, Tedi E. Asher, David R. Ambrozak, Phillip Scheinberg, Mohamad Rachid Boulassel, Jean-Pierre Routy, Richard A. Koup, Daniel C. Douek, Rafick-Pierre Sekaly, Lydie Trautmann
Journal: The Journal of Immunology
J Immunol (2012) 188 (3): 1156–1167.
https://doi.org/10.4049/jimmunol.1102610
Published: 01 February 2012
View articletitled, Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation
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Includes: Supplementary data
Journal Articles

Forced Expression of HLA-DM at the Surface of Dendritic Cells Increases Loading of Synthetic Peptides on MHC Class II Molecules and Modulates T Cell Responses

Free
Abdul Mohammad Pezeshki, Marie-Hélène Côté, Georges A. Azar, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Jacques Thibodeau
Journal: The Journal of Immunology
J Immunol (2011) 187 (1): 74–81.
https://doi.org/10.4049/jimmunol.1002747
Published: 01 July 2011
View articletitled, Forced Expression of HLA-DM at the Surface of Dendritic Cells Increases Loading of Synthetic Peptides on MHC Class II Molecules and Modulates T Cell Responses
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Includes: Supplementary data
Journal Articles

Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin β7

Free
Patricia Monteiro, Annie Gosselin, Vanessa Sue Wacleche, Mohamed El-Far, Elias A. Said, Hassen Kared, Nathalie Grandvaux, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Petronela Ancuta
Journal: The Journal of Immunology
J Immunol (2011) 186 (8): 4618–4630.
https://doi.org/10.4049/jimmunol.1004151
Published: 15 April 2011
View articletitled, Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin β7
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Includes: Supplementary data
Journal Articles

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

Free
Annie Gosselin, Patricia Monteiro, Nicolas Chomont, Felipe Diaz-Griffero, Elias A. Said, Simone Fonseca, Vanessa Wacleche, Mohamed El-Far, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Rafick-Pierre Sekaly, Petronela Ancuta
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1604–1616.
https://doi.org/10.4049/jimmunol.0903058
Published: 30 December 2009
View articletitled, Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection
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Includes: Supplementary data
Journal Articles

Human Activated T Lymphocytes Modulate IDO Expression in Tumors through Th1/Th2 Balance

Free
Jessica Godin-Ethier, Sandy Pelletier, Laïla-Aïcha Hanafi, Philippe O. Gannon, Marie-Andrée Forget, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Urszula Krzemien, Simon Tanguay, Jean-Baptiste Lattouf, Nathalie Arbour, Réjean Lapointe
Journal: The Journal of Immunology
J Immunol (2009) 183 (12): 7752–7760.
https://doi.org/10.4049/jimmunol.0901004
Published: 15 December 2009
View articletitled, Human Activated T Lymphocytes Modulate IDO Expression in Tumors through Th1/Th2 Balance
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Includes: Supplementary data
Journal Articles

Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study

Free
Alexandre Iannello, Mohamed-Rachid Boulassel, Suzanne Samarani, Olfa Debbeche, Cécile Tremblay, Emil Toma, Jean-Pierre Routy, Ali Ahmad
Journal: The Journal of Immunology
J Immunol (2010) 184 (1): 114–126.
https://doi.org/10.4049/jimmunol.0901967
Published: 10 December 2009
View articletitled, Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study
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Includes: Supplementary data
Journal Articles

4-1BBL Induces TNF Receptor-Associated Factor 1-Dependent Bim Modulation in Human T Cells and Is a Critical Component in the Costimulation-Dependent Rescue of Functionally Impaired HIV-Specific CD8 T Cells

Free
Chao Wang, Tao Wen, Jean-Pierre Routy, Nicole F. Bernard, Rafick P. Sekaly, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2007) 179 (12): 8252–8263.
https://doi.org/10.4049/jimmunol.179.12.8252
Published: 15 December 2007
View articletitled, 4-1BBL Induces TNF Receptor-Associated Factor 1-Dependent Bim Modulation in Human T Cells and Is a Critical Component in the Costimulation-Dependent Rescue of Functionally Impaired HIV-Specific CD8 T Cells
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Journal Articles

The Duration of Exposure to HIV Modulates the Breadth and the Magnitude of HIV-Specific Memory CD4+ T Cells

Free
Souheil-Antoine Younes, Lydie Trautmann, Bader Yassine-Diab, Lena H. Kalfayan, Anne-Elen Kernaleguen, Thomas O. Cameron, Rachid Boulassel, Lawrence J. Stern, Jean-Pierre Routy, Zvi Grossman, Alain R. Dumont, Rafick-Pierre Sekaly
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 788–797.
https://doi.org/10.4049/jimmunol.178.2.788
Published: 15 January 2007
View articletitled, The Duration of Exposure to HIV Modulates the Breadth and the Magnitude of HIV-Specific Memory CD4+ T Cells
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Journal Articles

Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL

Free
Lena Serghides, Jacob Bukczynski, Tao Wen, Chao Wang, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Rafick-Pierre Sekaly, Mario Ostrowski, Nicole F. Bernard, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6368–6377.
https://doi.org/10.4049/jimmunol.175.10.6368
Published: 15 November 2005
View articletitled, Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL
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Journal Articles

Enhancement of HIV-Specific CD8 T Cell Responses by Dual Costimulation with CD80 and CD137L

Free
Jacob Bukczynski, Tao Wen, Chao Wang, Natasha Christie, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Colin M. Kovacs, Kelly S. MacDonald, Mario Ostrowski, Rafick-Pierre Sekaly, Nicole F. Bernard, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6378–6389.
https://doi.org/10.4049/jimmunol.175.10.6378
Published: 15 November 2005
View articletitled, Enhancement of HIV-Specific CD8 T Cell Responses by Dual Costimulation with CD80 and CD137L
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Journal Articles

Longitudinal Assessment of Changes in HIV-Specific Effector Activity in HIV-Infected Patients Starting Highly Active Antiretroviral Therapy in Primary Infection

Free
Galit Alter, George Hatzakis, Christos Micheal Tsoukas, Karen Pelley, Danielle Rouleau, Roger LeBlanc, Jean-Guy Baril, Harold Dion, Eric Lefebvre, Réjean Thomas, Pierre Côté, Normand Lapointe, Jean-Pierre Routy, Rafik-Pierre Sékaly, Brian Conway, Nicole Flore Bernard
Journal: The Journal of Immunology
J Immunol (2003) 171 (1): 477–488.
https://doi.org/10.4049/jimmunol.171.1.477
Published: 01 July 2003
View articletitled, Longitudinal Assessment of Changes in HIV-Specific Effector Activity in HIV-Infected Patients Starting Highly Active Antiretroviral Therapy in Primary Infection
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