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Jeanette H. W. Leusen
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Journal Articles

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo

Connor A. Richterich, Meike E. W. Logtenberg, Marco J. H. Jansen, Mireille Toebes, Kaspar Bresser, Anne Borst, Anouk P. Jurgens, Jeanette H. W. Leusen, Ton N. Schumacher
Journal: The Journal of Immunology
J Immunol (2024) 213 (8): 1244–1254.
https://doi.org/10.4049/jimmunol.2300372
Published: 30 August 2024
View article titled, ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo
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Includes: Supplementary data
Journal Articles

IgG Subclass-Dependent Pulmonary Antigen Retention during Acute IgG-Dependent Systemic Anaphylaxis in Mice

Biliana Todorova, Ophélie Godon, Eva Conde, Caitlin M. Gillis, Bruno Iannascoli, Odile Richard-Le Goff, Daniel Fiole, Lubka T. Roumenina, Jeanette H. W. Leusen, Andrew J. Murphy, Lynn E. Macdonald, Laurent L. Reber, Friederike Jönsson, Pierre Bruhns
Journal: The Journal of Immunology
J Immunol (2022) 209 (7): 1243–1251.
https://doi.org/10.4049/jimmunol.2200234
Published: 01 October 2022
View article titled, IgG Subclass-Dependent Pulmonary Antigen Retention during Acute IgG-Dependent Systemic Anaphylaxis in Mice
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Includes: Supplementary data
Journal Articles

Comment on “Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells”

Mitchell Evers, Elizabeth Kruse, Firas Hamdan, Robert-Jan Lebbink, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2018) 200 (8): 2515–2516.
https://doi.org/10.4049/jimmunol.1800087
Published: 15 April 2018
View article titled, Comment on “Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells”
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Journal Articles

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions

Arianne M. Brandsma, Toine ten Broeke, Evelien van Dueren den Hollander, Thomas G. Caniels, Tineke Kardol-Hoefnagel, Jürgen Kuball, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2017) 199 (7): 2432–2439.
https://doi.org/10.4049/jimmunol.1601929
Published: 01 October 2017
View article titled, Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions
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Includes: Supplementary data
Journal Articles

The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor–Mediated Cross-Linking

Marije B. Overdijk, J. H. Marco Jansen, Maaike Nederend, Jeroen J. Lammerts van Bueren, Richard W. J. Groen, Paul W. H. I. Parren, Jeanette H. W. Leusen, Peter Boross
Journal: The Journal of Immunology
J Immunol (2016) 197 (3): 807–813.
https://doi.org/10.4049/jimmunol.1501351
Published: 01 August 2016
View article titled, The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor–Mediated Cross-Linking
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Includes: Supplementary data
Journal Articles

FcRγ-Chain ITAM Signaling Is Critically Required for Cross-Presentation of Soluble Antibody–Antigen Complexes by Dendritic Cells

Peter Boross, Nadine van Montfoort, Daphne A. C. Stapels, Cees E. van der Poel, Christian Bertens, Jan Meeldijk, J. H. Marco Jansen, J. Sjef Verbeek, Ferry Ossendorp, Richard Wubbolts, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5506–5514.
https://doi.org/10.4049/jimmunol.1302012
Published: 01 December 2014
View article titled, FcRγ-Chain ITAM Signaling Is Critically Required for Cross-Presentation of Soluble Antibody–Antigen Complexes by Dendritic Cells
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Includes: Supplementary data
Journal Articles

IgG Antibodies in Food Allergy Influence Allergen–Antibody Complex Formation and Binding to B Cells: A Role for Complement Receptors

Laura A. P. M. Meulenbroek, Renske J. de Jong, Constance F. den Hartog Jager, Hanneke N. Monsuur, Diana Wouters, Alma J. Nauta, Léon M. J. Knippels, R. J. Joost van Neerven, Bert Ruiter, Jeanette H. W. Leusen, C. Erik Hack, Carla A. F. M. Bruijnzeel-Koomen, André C. Knulst, Johan Garssen, Els van Hoffen
Journal: The Journal of Immunology
J Immunol (2013) 191 (7): 3526–3533.
https://doi.org/10.4049/jimmunol.1202398
Published: 01 October 2013
View article titled, IgG Antibodies in Food Allergy Influence Allergen–Antibody Complex Formation and Binding to B Cells: A Role for Complement Receptors
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Includes: Supplementary data
Journal Articles

Crosstalk between Human IgG Isotypes and Murine Effector Cells

Marije B. Overdijk, Sandra Verploegen, Antonio Ortiz Buijsse, Tom Vink, Jeanette H. W. Leusen, Wim K. Bleeker, Paul W. H. I. Parren
Journal: The Journal of Immunology
J Immunol (2012) 189 (7): 3430–3438.
https://doi.org/10.4049/jimmunol.1200356
Published: 01 October 2012
View article titled, Crosstalk between Human IgG Isotypes and Murine Effector Cells
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Includes: Supplementary data
Journal Articles

Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing

Stefan Lohse, Stefanie Derer, Thomas Beyer, Katja Klausz, Matthias Peipp, Jeanette H. W. Leusen, Jan G. J. van de Winkel, Michael Dechant, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3770–3778.
https://doi.org/10.4049/jimmunol.1003082
Published: 15 March 2011
View article titled, Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing
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Includes: Supplementary data
Journal Articles

Functional Characteristics of the High Affinity IgG Receptor, FcγRI

In Special Collection:
Brief Reviews
Cees E. van der Poel, Robbert M. Spaapen, Jan G. J. van de Winkel, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2011) 186 (5): 2699–2704.
https://doi.org/10.4049/jimmunol.1003526
Published: 01 March 2011
View article titled, Functional Characteristics of the High Affinity IgG Receptor, FcγRI
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Journal Articles

Inside-Out Regulation of FcαRI (CD89) Depends on PP2A

Jantine E. Bakema, Annie Bakker, Simone de Haij, Henk Honing, Madelon Bracke, Leo Koenderman, Gestur Vidarsson, Jan G. J. van de Winkel, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2008) 181 (6): 4080–4088.
https://doi.org/10.4049/jimmunol.181.6.4080
Published: 15 September 2008
View article titled, Inside-Out Regulation of FcαRI (CD89) Depends on PP2A
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Journal Articles

Filamin A Stabilizes FcγRI Surface Expression and Prevents Its Lysosomal Routing

Jeffrey M. Beekman, Cees E. van der Poel, Joke A. van der Linden, Debbie L. C. van den Berg, Peter V. E. van den Berghe, Jan G. J. van de Winkel, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2008) 180 (6): 3938–3945.
https://doi.org/10.4049/jimmunol.180.6.3938
Published: 15 March 2008
View article titled, Filamin A Stabilizes FcγRI Surface Expression and Prevents Its Lysosomal Routing
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Journal Articles

FcR γ-Chain Dependent Signaling in Immature Neutrophils Is Mediated by FcαRI, but Not by FcγRI

Marielle A. Otten, Jeanette H. W. Leusen, Esther Rudolph, Joke A. van der Linden, Robert H. J. Beelen, Jan G. J. van de Winkel, Marjolein van Egmond
Journal: The Journal of Immunology
J Immunol (2007) 179 (5): 2918–2924.
https://doi.org/10.4049/jimmunol.179.5.2918
Published: 01 September 2007
View article titled, FcR γ-Chain Dependent Signaling in Immature Neutrophils Is Mediated by FcαRI, but Not by FcγRI
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Journal Articles

Signaling through Mutants of the IgA Receptor CD89 and Consequences for Fc Receptor γ-Chain Interaction

Jantine E. Bakema, Simone de Haij, Constance F. den Hartog-Jager, Johanna Bakker, Gestur Vidarsson, Marjolein van Egmond, Jan G. J. van de Winkel, Jeanette H. W. Leusen
Journal: The Journal of Immunology
J Immunol (2006) 176 (6): 3603–3610.
https://doi.org/10.4049/jimmunol.176.6.3603
Published: 15 March 2006
View article titled, Signaling through Mutants of the IgA Receptor CD89 and Consequences for Fc Receptor γ-Chain Interaction
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Journal Articles

Central Role of Complement in Passive Protection by Human IgG1 and IgG2 Anti-pneumococcal Antibodies in Mice

Eirikur Saeland, Gestur Vidarsson, Jeanette H. W. Leusen, Evert van Garderen, Moon H. Nahm, Henriette Vile-Weekhout, Vanessa Walraven, Annette M. Stemerding, J. Sjef Verbeek, Ger T. Rijkers, Wietse Kuis, Elisabeth A. M. Sanders, Jan G. J. van de Winkel
Journal: The Journal of Immunology
J Immunol (2003) 170 (12): 6158–6164.
https://doi.org/10.4049/jimmunol.170.12.6158
Published: 15 June 2003
View article titled, Central Role of Complement in Passive Protection by Human IgG1 and IgG2 Anti-pneumococcal Antibodies in Mice
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Journal Articles

Mac-1 (CD11b/CD18) as Accessory Molecule for FcαR (CD89) Binding of IgA

Annemiek B. van Spriel, Jeanette H. W. Leusen, Henriëtte Vilé, Jan G. J. van de Winkel
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3831–3836.
https://doi.org/10.4049/jimmunol.169.7.3831
Published: 01 October 2002
View article titled, Mac-1 (CD11b/CD18) as Accessory Molecule for FcαR (CD89) Binding of IgA
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Journal Articles

Cytolytic Mechanisms and Expression of Activation-Regulating Receptors on Effector-Type CD8+CD45RA+CD27− Human T Cells

Paul A. Baars, Laura M. Ribeiro do Couto, Jeanette H. W. Leusen, Berend Hooibrink, Taco W. Kuijpers, Susanne M. A. Lens, René A. W. van Lier
Journal: The Journal of Immunology
J Immunol (2000) 165 (4): 1910–1917.
https://doi.org/10.4049/jimmunol.165.4.1910
Published: 15 August 2000
View article titled, Cytolytic Mechanisms and Expression of Activation-Regulating Receptors on Effector-Type CD8<sup>+</sup>CD45RA<sup>+</sup>CD27<sup>−</sup> Human T Cells
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