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Jeffrey S. Miller
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Journal Articles

NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

Free
Jenna K. Dick, Jules A. Sangala, Venkatramana D. Krishna, Aaron Khaimraj, Lydia Hamel, Spencer M. Erickson, Dustin Hicks, Yvette Soigner, Laura E. Covill, Alexander K. Johnson, Michael J. Ehrhardt, Keenan Ernste, Petter Brodin, Richard A. Koup, Alka Khaitan, Carly Baehr, Beth K. Thielen, Christine M. Henzler, Caleb Skipper, Jeffrey S. Miller, Yenan T. Bryceson, Jianming Wu, Chandy C. John, Angela Panoskaltsis-Mortari, Alberto Orioles, Marie E. Steiner, Maxim C. J. Cheeran, Marco Pravetoni, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2024) 213 (10): 1452–1466.
https://doi.org/10.4049/jimmunol.2400395
Published: 11 October 2024
View articletitled, NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children
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Includes: Supplementary data
Journal Articles

NK Cells from Human Cytomegalovirus–Seropositive Individuals Have a Distinct Metabolic Profile That Correlates with Elevated mTOR Signaling

Free
John R. Lozada, Bin Zhang, Jeffrey S. Miller, Frank Cichocki
Journal: The Journal of Immunology
J Immunol (2023) 211 (4): 539–550.
https://doi.org/10.4049/jimmunol.2200851
Published: 21 June 2023
View articletitled, NK Cells from Human Cytomegalovirus–Seropositive Individuals Have a Distinct Metabolic Profile That Correlates with Elevated mTOR Signaling
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Includes: Supplementary data
Journal Articles

Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production

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James D. Dahlvang, Jenna K. Dick, Jules A. Sangala, Philippa R. Kennedy, Emily J. Pomeroy, Kristin M. Snyder, Juliette M. Moushon, Claire E. Thefaine, Jianming Wu, Sara E. Hamilton, Martin Felices, Jeffrey S. Miller, Bruce Walcheck, Beau R. Webber, Branden S. Moriarity, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1108–1122.
https://doi.org/10.4049/jimmunol.2200488
Published: 06 March 2023
View articletitled, Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production
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Includes: Supplementary data
Journal Articles

Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01

Free
Lisbeth A. Guethlein, Niassan Beyzaie, Neda Nemat-Gorgani, Tao Wang, Vidhyalakshmi Ramesh, Wesley M. Marin, Jill A. Hollenbach, Johannes Schetelig, Stephen R. Spellman, Steven G. E. Marsh, Sarah Cooley, Daniel J. Weisdorf, Paul J. Norman, Jeffrey S. Miller, Peter Parham
Journal: The Journal of Immunology
J Immunol (2021) 206 (12): 3064–3072.
https://doi.org/10.4049/jimmunol.2100119
Published: 15 June 2021
View articletitled, Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01
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Includes: Supplementary data
Journal Articles

Hypoxia profoundly alters Natural Killer cell phenotype and function: implications for immunotherapy within the solid tumor microenvironment

Free
Upasana Sunil Arvindam, Philippa Kennedy, Brianna Ettestad, Shee Kwan Phung, Peter Hinderlie, James Lim, Jeffrey S Miller, Martin Felices
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 56.17.
https://doi.org/10.4049/jimmunol.206.Supp.56.17
Published: 01 May 2021
View articletitled, Hypoxia profoundly alters Natural Killer cell phenotype and function: implications for immunotherapy within the solid tumor microenvironment
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Journal Articles

Ascorbic Acid Promotes KIR Demethylation during Early NK Cell Differentiation

Free
Cheng-Ying Wu, Bin Zhang, Hansol Kim, Stephen K. Anderson, Jeffrey S. Miller, Frank Cichocki
Journal: The Journal of Immunology
J Immunol (2020) 205 (6): 1513–1523.
https://doi.org/10.4049/jimmunol.2000212
Published: 15 September 2020
View articletitled, Ascorbic Acid Promotes KIR Demethylation during Early NK Cell Differentiation
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Includes: Supplementary data
Journal Articles

Synergistic activity between IL-15 signaling and checkpoint blockade drives enhanced NK cell expansion and tumor control in ovarian cancer

Free
Martin Felices, Laura Bendzick, Behiye Kodal, Peter Hinderlie, Jeffrey S Miller, Melissa Geller
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 136.22.
https://doi.org/10.4049/jimmunol.202.Supp.136.22
Published: 01 May 2019
View articletitled, Synergistic activity between IL-15 signaling and checkpoint blockade drives enhanced NK cell expansion and tumor control in ovarian cancer
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Journal Articles

CITN11-02 phase I trial of subcutaneous recombinant human IL-15 (rhIL-15) is associated with expansion of circulating CD56+ NK cells and CD8+ T cells

Free
Chihiro Morishima, Douglas G McNeel, Manish R Patel, Holbrook E.K. Kohrt, Thomas A Waldmann, John A Thompson, Kevin C Conlon, Paul M Sondel, Heather A Wakelee, Minjun C Apodaca, Steven P Fling, Mary L Disis, Steven P Creekmore, Jeffrey S Miller
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 75.16.
https://doi.org/10.4049/jimmunol.196.Supp.75.16
Published: 01 May 2016
View articletitled, CITN11-02 phase I trial of subcutaneous recombinant human IL-15 (rhIL-15) is associated with expansion of circulating CD56+ NK cells and CD8+ T cells
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Journal Articles

CD16-IL15-CD33 Trispecific Killer Engager (TriKE) induces NK cell expansion, persistence, and myeloid blast antigen specific killing.

Free
Martin Felices, Daniel A. Vallera, Ron McElmurry, Alexander J.L. Lenvik, Sami Chu, Deborah Todhunter, Elizabeth P. Taras, Jakub Tolar, Bruce R Blazar, Jeffrey S Miller
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 75.8.
https://doi.org/10.4049/jimmunol.196.Supp.75.8
Published: 01 May 2016
View articletitled, CD16-IL15-CD33 Trispecific Killer Engager (TriKE) induces NK cell expansion, persistence, and myeloid blast antigen specific killing.
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Journal Articles

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

Free
Amir Horowitz, Lisbeth A. Guethlein, Neda Nemat-Gorgani, Paul J. Norman, Sarah Cooley, Jeffrey S. Miller, Peter Parham
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4524–4536.
https://doi.org/10.4049/jimmunol.1401990
Published: 01 November 2015
View articletitled, Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation
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Includes: Supplementary data
Journal Articles

Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation

Free
Martin Felices, Dave E. M. Ankarlo, Todd R. Lenvik, Heather H. Nelson, Bruce R. Blazar, Michael R. Verneris, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2014) 193 (7): 3344–3354.
https://doi.org/10.4049/jimmunol.1400534
Published: 01 October 2014
View articletitled, Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation
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Includes: Supplementary data
Journal Articles

Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia

Free
Sarah Cooley, Daniel J. Weisdorf, Lisbeth A. Guethlein, John P. Klein, Tao Wang, Steven G. E. Marsh, Stephen Spellman, Michael D. Haagenson, Koy Saeturn, Martha Ladner, Elizabeth Trachtenberg, Peter Parham, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2014) 192 (10): 4592–4600.
https://doi.org/10.4049/jimmunol.1302517
Published: 15 May 2014
View articletitled, Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia
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Includes: Supplementary data
Journal Articles

Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand

Free
Martin Felices, Todd R. Lenvik, Dave E. M. Ankarlo, Bree Foley, Julie Curtsinger, Xianghua Luo, Bruce R. Blazar, Stephen K. Anderson, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3889–3897.
https://doi.org/10.4049/jimmunol.1302601
Published: 15 April 2014
View articletitled, Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand
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Includes: Supplementary data
Journal Articles

Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen

Free
Bree Foley, Sarah Cooley, Michael R. Verneris, Julie Curtsinger, Xianghua Luo, Edmund K. Waller, Claudio Anasetti, Daniel Weisdorf, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2012) 189 (10): 5082–5088.
https://doi.org/10.4049/jimmunol.1201964
Published: 15 November 2012
View articletitled, Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen
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Includes: Supplementary data
Journal Articles

Cutting Edge: MicroRNA-181 Promotes Human NK Cell Development by Regulating Notch Signaling

Free
Frank Cichocki, Martin Felices, Valarie McCullar, Steven R. Presnell, Ahmad Al-Attar, Charles T. Lutz, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2011) 187 (12): 6171–6175.
https://doi.org/10.4049/jimmunol.1100835
Published: 15 December 2011
View articletitled, Cutting Edge: MicroRNA-181 Promotes Human NK Cell Development by Regulating Notch Signaling
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Includes: Supplementary data
Journal Articles

Cutting Edge: KIR Antisense Transcripts Are Processed into a 28-Base PIWI-Like RNA in Human NK Cells

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Frank Cichocki, Todd Lenvik, Neeraj Sharma, Gong Yun, Stephen K. Anderson, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2010) 185 (4): 2009–2012.
https://doi.org/10.4049/jimmunol.1000855
Published: 15 August 2010
View articletitled, Cutting Edge: KIR Antisense Transcripts Are Processed into a 28-Base PIWI-Like RNA in Human NK Cells
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Includes: Supplementary data
Journal Articles

Antisense transcripts negatively regulate transcription of multiple variegated killer immunoglobulin-like receptor (KIR) genes (136.38)

Free
Frank Cichocki, Todd Lenvik, Stephen K Anderson, Jeffrey S Miller
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 136.38.
https://doi.org/10.4049/jimmunol.182.Supp.136.38
Published: 01 April 2009
View articletitled, Antisense transcripts negatively regulate transcription of multiple variegated killer immunoglobulin-like receptor (KIR) genes (136.38)
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Journal Articles

Umbilical Cord Blood T Cells Express Multiple Natural Cytotoxicity Receptors after IL-15 Stimulation, but Only NKp30 Is Functional

Free
Qin Tang, Bartosz Grzywacz, Hongbo Wang, Nandini Kataria, Qing Cao, John E. Wagner, Bruce R. Blazar, Jeffrey S. Miller, Michael R. Verneris
Journal: The Journal of Immunology
J Immunol (2008) 181 (7): 4507–4515.
https://doi.org/10.4049/jimmunol.181.7.4507
Published: 01 October 2008
View articletitled, Umbilical Cord Blood T Cells Express Multiple Natural Cytotoxicity Receptors after IL-15 Stimulation, but Only NKp30 Is Functional
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Journal Articles

Epigenetic Control of Highly Homologous Killer Ig-Like Receptor Gene Alleles

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Huei-Wei Chan, Jeffrey S. Miller, Mikel B. Moore, Charles T. Lutz
Journal: The Journal of Immunology
J Immunol (2005) 175 (9): 5966–5974.
https://doi.org/10.4049/jimmunol.175.9.5966
Published: 01 November 2005
View articletitled, Epigenetic Control of Highly Homologous Killer Ig-Like Receptor Gene Alleles
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Journal Articles

Human Embryonic Stem Cell-Derived NK Cells Acquire Functional Receptors and Cytolytic Activity

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Petter S. Woll, Colin H. Martin, Jeffrey S. Miller, Dan S. Kaufman
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 5095–5103.
https://doi.org/10.4049/jimmunol.175.8.5095
Published: 15 October 2005
View articletitled, Human Embryonic Stem Cell-Derived NK Cells Acquire Functional Receptors and Cytolytic Activity
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