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Journal Articles

Murine Inducible Nitric Oxide Synthase Expression Is Essential for Antifungal Defenses in Kidneys during Disseminated Cryptococcus deneoformans Infection

Kristie D. Goughenour, Jessica Zhao, Jintao Xu, Ziyin P. Zhao, Anutosh Ganguly, Christine M. Freeman, Michal A. Olszewski
Journal: The Journal of Immunology
J Immunol (2021) 207 (8): 2096–2106.
https://doi.org/10.4049/jimmunol.2100386
Published: 15 October 2021
View article titled, Murine Inducible Nitric Oxide Synthase Expression Is Essential for Antifungal Defenses in Kidneys during Disseminated <em>Cryptococcus deneoformans</em> Infection
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Includes: Supplementary data
Journal Articles

CXCR3 gene deletion in murine cryptococcal meningoencephalitis leads to a shift in CD4-T Cell transcriptional profile away from hyperactive/cytotoxic phenotype.

Jacob William Shelton Martens, Jintao Xu, Kristie D Goughenour, Harini Subbiah, Doyun L. Kwak, Brian L. Parkin, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 99.31.
https://doi.org/10.4049/jimmunol.206.Supp.99.31
Published: 01 May 2021
View article titled, CXCR3 gene deletion in murine cryptococcal meningoencephalitis leads to a shift in CD4-T Cell transcriptional profile away from hyperactive/cytotoxic phenotype.
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Journal Articles

Harnessing Regulatory T cells to Suppress Pathological Immune Response during Cryptococcus neoformans Meningoencephalitis

Jintao Xu, Kristie Goughenour, Ziyin Zhao, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 16.12.
https://doi.org/10.4049/jimmunol.206.Supp.16.12
Published: 01 May 2021
View article titled, Harnessing Regulatory T cells to Suppress Pathological Immune Response during <em>Cryptococcus neoformans</em> Meningoencephalitis
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Journal Articles

Murine iNOS expression is essential for antifungal defenses in kidneys during disseminated cryptococcosis

Kristie D Goughenour, Jessica Zhao, Jintao Xu, Peter Zhao, Christine Freeman, Anutosh Ganguly, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 16.30.
https://doi.org/10.4049/jimmunol.206.Supp.16.30
Published: 01 May 2021
View article titled, Murine iNOS expression is essential for antifungal defenses in kidneys during disseminated cryptococcosis
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Journal Articles

The Function of Brain Th1-like regulatory T cells in Suppressing Lethal Immune Pathology and Neurological Deterioration during Cryptococcus neoformans Meningoencephalitis

Jintao Xu, Jessica Zhao, Michael Ivey, Rafael Lopez, Brandon McClellan, Steven Do, Akanksha Malepati, Samantha Kroon, Alexa Mysel, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 156.21.
https://doi.org/10.4049/jimmunol.204.Supp.156.21
Published: 01 May 2020
View article titled, The Function of Brain Th1-like regulatory T cells in Suppressing Lethal Immune Pathology and Neurological Deterioration during <em>Cryptococcus neoformans</em> Meningoencephalitis
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Journal Articles

Infiltrated monocyte and T cell interaction drives immunopathology in the brain during cryptococcal meningoencephalitis

Jintao Xu, Mike Ivey, Jessica Koble, Rafael Lopez, Claire Mechler, Lori Neal, Peter Williamson, Benjamin Segal, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 190.14.
https://doi.org/10.4049/jimmunol.202.Supp.190.14
Published: 01 May 2019
View article titled, Infiltrated monocyte and T cell interaction drives immunopathology in the brain during cryptococcal meningoencephalitis
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Journal Articles

Trehalose-6-phosphate synthase-deletion in Cryptococcus neoformans elicits rapid innate fungal clearance from the lungs with early neutrophil accumulation

Jintao Xu, Mack Reynolds, Xiumiao He, Xueli Gao, Michael Ivey, Jess Kolbe, Raphael Lopez, Claire Mechler, John Perfect, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 190.9.
https://doi.org/10.4049/jimmunol.202.Supp.190.9
Published: 01 May 2019
View article titled, Trehalose-6-phosphate synthase-deletion in <em>Cryptococcus neoformans</em> elicits rapid innate fungal clearance from the lungs with early neutrophil accumulation
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Journal Articles

Infiltrating CCR2+ Monocytes Drive Lethal Immunopathology during Cryptococcal Meningoencephalitis

Jintao Xu, Lori Neal, Mike Ivey, Rafael Lopez, Benjamin Segal, John J. Osterholzer, Peter R. Williamson, Michal A. Olszewski
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 52.16.
https://doi.org/10.4049/jimmunol.200.Supp.52.16
Published: 01 May 2018
View article titled, Infiltrating CCR2+ Monocytes Drive Lethal Immunopathology during Cryptococcal Meningoencephalitis
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Journal Articles

Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection

Jintao Xu, Adam Flaczyk, Lori M. Neal, Zhenzong Fa, Alison J. Eastman, Antoni N. Malachowski, Daphne Cheng, Bethany B. Moore, Jeffrey L. Curtis, John J. Osterholzer, Michal A. Olszewski
Journal: The Journal of Immunology
J Immunol (2017) 198 (9): 3548–3557.
https://doi.org/10.4049/jimmunol.1700057
Published: 01 May 2017
View article titled, Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection
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Journal Articles

CD4 T cell expression of PTIP is necessary for epigenetic maintenance of Th1/Th17 responses during Cryptococcus neoformans infection

Alison J Eastman, Kanav Gupta, Lori Neal, Jintao Xu, Guolei Zhou, Antoni Malachowski, Gregory R. Dressler, Steven L Kunkel, Matthew Schaller, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 55.8.
https://doi.org/10.4049/jimmunol.196.Supp.55.8
Published: 01 May 2016
View article titled, CD4 T cell expression of PTIP is necessary for epigenetic maintenance of Th1/Th17 responses during <em>Cryptococcus neoformans</em> infection
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Journal Articles

Early TNFα signaling results in pulmonary DC1 polarization and programing of murine myeloid precursor cells in the bone marrow towards DC1 polarization throughout Cryptococcus neoformans infection

Alison J Eastman, Nicole Potchen, Guolei Zhou, Jintao Xu, Lori Neal, Antoni Malachowski, Steven L Kunkel, Ilona Kryczek, John J Osterholzer, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 126.10.
https://doi.org/10.4049/jimmunol.196.Supp.126.10
Published: 01 May 2016
View article titled, Early TNFα signaling results in pulmonary DC1 polarization and programing of murine myeloid precursor cells in the bone marrow towards DC1 polarization throughout <em>Cryptococcus neoformans</em> infection
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Journal Articles

Dual roles of scavenger receptor MARCO in innate versus adaptive immune responses during Cryptococcus neoformans infection

JINTAO XU, Adam Flaczyk, Alison J Eastman, Lori Neal, Guolei Zhao, Antoni Malachowski, Jay Akolkar, John J Osterholzer, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 135.18.
https://doi.org/10.4049/jimmunol.196.Supp.135.18
Published: 01 May 2016
View article titled, Dual roles of scavenger receptor MARCO in innate versus adaptive immune responses during <em>Cryptococcus neoformans</em> infection
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Journal Articles

Early TNFα signaling promotes classical activation of dendritic cells in lung associated lymph nodes to prime development of protective immunity against cryptococcal infection

JINTAO XU, Alison J Eastman, Adam Flaczyk, Lori Neal, Guolei Zhao, Daphne Cheng, Antoni Malachowski, Mohammed Yosri, Jeffrey L Curtis, John J Osterholzer, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 135.17.
https://doi.org/10.4049/jimmunol.196.Supp.135.17
Published: 01 May 2016
View article titled, Early TNFα signaling promotes classical activation of dendritic cells in lung associated lymph nodes to prime development of protective immunity against cryptococcal infection
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Journal Articles

Inflammation and immune cell recruitment in the CNS following disseminated Cryptococcus neoformans infection

Lori M Neal, Enze Xing, Jintao Xu, John J Osterholzer, Michal A Olszewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 135.16.
https://doi.org/10.4049/jimmunol.196.Supp.135.16
Published: 01 May 2016
View article titled, Inflammation and immune cell recruitment in the CNS following disseminated <em>Cryptococcus neoformans</em> infection
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