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Johan Grooten
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Journal Articles

The hyperinflammatory reactivity of post-asthma alveolar macrophages contributes to RSV-induced asthma exacerbations (HYP7P.269)

Johan Grooten, Bert Schepens, Muriel Smet, Xavier Saelens, Thomas Naessens
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 191.17.
https://doi.org/10.4049/jimmunol.194.Supp.191.17
Published: 01 May 2015
View article titled, The hyperinflammatory reactivity of post-asthma alveolar macrophages contributes to RSV-induced asthma exacerbations (HYP7P.269)
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Use of mRNA for vaccination or gene therapy: delivery route determines the verdict (P4316)

Charlotte Pollard, Gaëlle Vandermeulen, Guido Vanham, Johan Grooten, Véronique Préat, Stefaan De Koker
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 45.6.
https://doi.org/10.4049/jimmunol.190.Supp.45.6
Published: 01 May 2013
View article titled, Use of mRNA for vaccination or gene therapy: delivery route determines the verdict (P4316)
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Inflammatory DCs fail to present antigen but provide a crucial source of IL-12 in priming Th1 responses to CpG based vaccines. (P4514)

Stefaan De Koker, Monique Willart, Charlotte Pollard, Martin Guilliams, Bart Lambrecht, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 178.11.
https://doi.org/10.4049/jimmunol.190.Supp.178.11
Published: 01 May 2013
View article titled, Inflammatory DCs fail to present antigen but provide a crucial source of IL-12 in priming Th1 responses to CpG based vaccines. (P4514)
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Innate imprinting of resident alveolar macrophages in RSV-induced allergic asthma exacerbations (P6003)

Thomas Naessens, Bert Schepens, Charlotte Pollard, Pieter Bogaert, Stefaan De Koker, Xavier Saelens, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 120.2.
https://doi.org/10.4049/jimmunol.190.Supp.120.2
Published: 01 May 2013
View article titled, Innate imprinting of resident alveolar macrophages in RSV-induced allergic asthma exacerbations (P6003)
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Journal Articles

CpG-induced inflammatory DCs promote strong Th1/CTL responses to particulate antigens (52.11)

Stefaan De Koker, Bruno G. De Geest, Monique Willart, Jean Paul Remon, Bart Lambrecht, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 52.11.
https://doi.org/10.4049/jimmunol.186.Supp.52.11
Published: 01 April 2011
View article titled, CpG-induced inflammatory DCs promote strong Th1/CTL responses to particulate antigens (52.11)
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Innate imprinting of resident alveolar macrophages by a preceding allergic bronchial inflammation increases the inflammatory TLR-reactivity through an enhanced MyD88-independent signaling and the type I interferon, IFN-β. (55.5)

Thomas Naessens, Seppe Vander Beken, Stefaan De Koker, Stefan Lienenklaus, Nico Van Rooijen, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 55.5.
https://doi.org/10.4049/jimmunol.186.Supp.55.5
Published: 01 April 2011
View article titled, Innate imprinting of resident alveolar macrophages by a preceding allergic bronchial inflammation increases the inflammatory TLR-reactivity through an enhanced MyD88-independent signaling and the type I interferon, IFN-β. (55.5)
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Innate imprinting of resident alveolar macrophages by a preceding allergic bronchial inflammation increases the inflammatory reactivity through autocrine IFN-β. (141.18)

Thomas Naessens, Seppe Vander Beken, Stefaan De Koker, Stefan Lienenklaus, Luc Vakaet, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 141.18.
https://doi.org/10.4049/jimmunol.184.Supp.141.18
Published: 01 April 2010
View article titled, Innate imprinting of resident alveolar macrophages by a preceding allergic bronchial inflammation increases the inflammatory reactivity through autocrine IFN-β. (141.18)
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Journal Articles

Polyelectrolyte microcapsules: antigen delivery vehicles for potent induction of CTL responses (131.34)

Johan Grooten, Bruno De Geest, Thomas Naessens, Stefaan De Smedt, Stefaan De Koker
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 131.34.
https://doi.org/10.4049/jimmunol.184.Supp.131.34
Published: 01 April 2010
View article titled, Polyelectrolyte microcapsules: antigen delivery vehicles for potent induction of CTL responses (131.34)
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Journal Articles

Biodegradable Polyelectrolyte Microcapsules: Antigen Delivery Tools with Th17 Skewing Activity after Pulmonary Delivery

Stefaan De Koker, Thomas Naessens, Bruno G. De Geest, Pieter Bogaert, Jo Demeester, Stefaan De Smedt, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2010) 184 (1): 203–211.
https://doi.org/10.4049/jimmunol.0803591
Published: 14 December 2009
View article titled, Biodegradable Polyelectrolyte Microcapsules: Antigen Delivery Tools with Th17 Skewing Activity after Pulmonary Delivery
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Journal Articles

Lipoprotein I, a TLR2/4 Ligand Modulates Th2-Driven Allergic Immune Responses

Hilde Revets, Gwenda Pynaert, Johan Grooten, Patrick De Baetselier
Journal: The Journal of Immunology
J Immunol (2005) 174 (2): 1097–1103.
https://doi.org/10.4049/jimmunol.174.2.1097
Published: 15 January 2005
View article titled, Lipoprotein I, a TLR2/4 Ligand Modulates Th2-Driven Allergic Immune Responses
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Journal Articles

Airway IgG Counteracts Specific and Bystander Allergen-Triggered Pulmonary Inflammation by a Mechanism Dependent on FcγR and IFN-γ

Sarita Sehra, Gwenda Pynaert, Kurt Tournoy, Anuschka Haegeman, Patrick Matthys, Yohichi Tagawa, Romain Pauwels, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2003) 171 (4): 2080–2089.
https://doi.org/10.4049/jimmunol.171.4.2080
Published: 15 August 2003
View article titled, Airway IgG Counteracts Specific and Bystander Allergen-Triggered Pulmonary Inflammation by a Mechanism Dependent on FcγR and IFN-γ
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Journal Articles

Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives

Reinhilde Schoonjans, An Willems, Steve Schoonooghe, Walter Fiers, Johan Grooten, Nico Mertens
Journal: The Journal of Immunology
J Immunol (2000) 165 (12): 7050–7057.
https://doi.org/10.4049/jimmunol.165.12.7050
Published: 15 December 2000
View article titled, Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives
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Journal Articles

Macrophages Present Pinocytosed Exogenous Antigen Via MHC Class I Whereas Antigen Ingested by Receptor-Mediated Endocytosis Is Presented Via MHC Class II

Maikel P. Peppelenbosch, Marjory DeSmedt, Gwenda Pynaert, Sander J. H. van Deventer, Johan Grooten
Journal: The Journal of Immunology
J Immunol (2000) 165 (4): 1984–1991.
https://doi.org/10.4049/jimmunol.165.4.1984
Published: 15 August 2000
View article titled, Macrophages Present Pinocytosed Exogenous Antigen Via MHC Class I Whereas Antigen Ingested by Receptor-Mediated Endocytosis Is Presented Via MHC Class II
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Multiple Signal Transduction Pathways Regulate TNF-Induced Actin Reorganization in Macrophages: Inhibition of Cdc42-Mediated Filopodium Formation by TNF

Maikel Peppelenbosch, Elke Boone, Gareth E. Jones, S.J.H. van Deventer, Guy Haegeman, Walter Fiers, Johan Grooten, Anne J. Ridley
Journal: The Journal of Immunology
J Immunol (1999) 162 (2): 837–845.
https://doi.org/10.4049/jimmunol.162.2.837
Published: 15 January 1999
View article titled, Multiple Signal Transduction Pathways Regulate TNF-Induced Actin Reorganization in Macrophages: Inhibition of Cdc42-Mediated Filopodium Formation by TNF
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Quiescence-Inducing and Antiapoptotic Activities of IL-15 Enhance Secondary CD4+ T Cell Responsiveness to Antigen

Hans Dooms, Marjory Desmedt, Sabine Vancaeneghem, Pieter Rottiers, Vera Goossens, Walter Fiers, Johan Grooten
Journal: The Journal of Immunology
J Immunol (1998) 161 (5): 2141–2150.
https://doi.org/10.4049/jimmunol.161.5.2141
Published: 01 September 1998
View article titled, Quiescence-Inducing and Antiapoptotic Activities of IL-15 Enhance Secondary CD4<sup>+</sup> T Cell Responsiveness to Antigen
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Macrophages Induce Cellular Immunity by Activating Th1 Cell Responses and Suppressing Th2 Cell Responses

Marjory Desmedt, Pieter Rottiers, Hans Dooms, Walter Fiers, Johan Grooten
Journal: The Journal of Immunology
J Immunol (1998) 160 (11): 5300–5308.
https://doi.org/10.4049/jimmunol.160.11.5300
Published: 01 June 1998
View article titled, Macrophages Induce Cellular Immunity by Activating Th1 Cell Responses and Suppressing Th2 Cell Responses
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