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Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

Heather I. Fraser, Sarah Howlett, Jan Clark, Daniel B. Rainbow, Stephanie M. Stanford, Dennis J. Wu, Yi-Wen Hsieh, Christian J. Maine, Mikkel Christensen, Vijay Kuchroo, Linda A. Sherman, Patricia L. Podolin, John A. Todd, Charles A. Steward, Laurence B. Peterson, Nunzio Bottini, Linda S. Wicker

J Immunol (2015) 195 (10): 4841–4852.

DOI: https://doi.org/10.4049/jimmunol.1402654

Published: 15 November 2015

View article titled, Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

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Includes: Supplementary data

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Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Laura Esposito, Kara M. D. Hunter, Jan Clark, Daniel B. Rainbow, Helen Stevens, Jennifer Denesha, Simon Duley, Sarah Dawson, Gillian Coleman, Sarah Nutland, Gwynneth L. Bell, Carla Moran, Marcin Pekalski, John A. Todd, Linda S. Wicker

J Immunol (2014) 193 (2): 889–900.

DOI: https://doi.org/10.4049/jimmunol.1303389

Published: 15 July 2014

View article titled, Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

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Includes: Supplementary data

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Pillars Article: Genetic Analysis of Autoimmune Type 1 Diabetes Mellitus in Mice. Nature. 1991. 351: 542-547

John A. Todd, Timothy J. Aitman, Richard J. Cornall, Soumitra Ghosh, Jennifer R. S. Hall, Catherine M. Hearne, Andrew M. Knight, Jennifer M. Love, Marcia A. McAleer, Jan-Bas Prins, Nanda Rodrigues, Mark Lathrop, Alison Pressey, Nicole H. DeLarato, Laurence B. Peterson, Linda S. Wicker

J Immunol (2014) 193 (1): 7–12.

Published: 01 July 2014

View article titled, Pillars Article: Genetic Analysis of Autoimmune Type 1 Diabetes Mellitus in Mice. Nature. 1991. 351: 542-547

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Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors

J Immunol (2013) 190 (6): 2554–2566.

DOI: https://doi.org/10.4049/jimmunol.1202914

Published: 15 March 2013

View article titled, Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors

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Includes: Supplementary data

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Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4⁺CD25⁺ Regulatory T Cell Function

Garima Garg, Jennifer R. Tyler, Jennie H. M. Yang, Antony J. Cutler, Kate Downes, Marcin Pekalski, Gwynneth L. Bell, Sarah Nutland, Mark Peakman, John A. Todd, Linda S. Wicker, Timothy I. M. Tree

J Immunol (2012) 188 (9): 4644–4653.

DOI: https://doi.org/10.4049/jimmunol.1100272

Published: 01 May 2012

View article titled, Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cell Function

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Includes: Supplementary data

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Identification of Cd101 as a Susceptibility Gene for Novosphingobium aromaticivorans-Induced Liver Autoimmunity

Javid P. Mohammed, Michael E. Fusakio, Daniel B. Rainbow, Carolyn Moule, Heather I. Fraser, Jan Clark, John A. Todd, Laurence B. Peterson, Paul B. Savage, Marsha Wills-Karp, William M. Ridgway, Linda S. Wicker, Jochen Mattner

J Immunol (2011) 187 (1): 337–349.

DOI: https://doi.org/10.4049/jimmunol.1003525

Published: 01 July 2011

View article titled, Identification of Cd101 as a Susceptibility Gene for Novosphingobium aromaticivorans-Induced Liver Autoimmunity

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Includes: Supplementary data

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Evidence that Cd101 Is an Autoimmune Diabetes Gene in Nonobese Diabetic Mice

J Immunol (2011) 187 (1): 325–336.

DOI: https://doi.org/10.4049/jimmunol.1003523

Published: 01 July 2011

View article titled, Evidence that Cd101 Is an Autoimmune Diabetes Gene in Nonobese Diabetic Mice

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Includes: Supplementary data

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Nonobese Diabetic Congenic Strain Analysis of Autoimmune Diabetes Reveals Genetic Complexity of the Idd18 Locus and Identifies Vav3 as a Candidate Gene

Heather I. Fraser, Calliope A. Dendrou, Barry Healy, Daniel B. Rainbow, Sarah Howlett, Luc J. Smink, Simon Gregory, Charles A. Steward, John A. Todd, Laurence B. Peterson, Linda S. Wicker

J Immunol (2010) 184 (9): 5075–5084.

DOI: https://doi.org/10.4049/jimmunol.0903734

Published: 01 May 2010

View article titled, Nonobese Diabetic Congenic Strain Analysis of Autoimmune Diabetes Reveals Genetic Complexity of the Idd18 Locus and Identifies Vav3 as a Candidate Gene

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Includes: Supplementary data

Journal Articles

NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese Diabetic Mice

Lisa M. Maier, Sarah K. Howlett, Kara M. Rainbow, Jan Clark, Joanna M. M. Howson, John A. Todd, Linda S. Wicker

J Immunol (2008) 181 (10): 7073–7080.

DOI: https://doi.org/10.4049/jimmunol.181.10.7073

Published: 15 November 2008

View article titled, NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese Diabetic Mice

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Journal Articles

Interactions between Idd5.1/Ctla4 and Other Type 1 Diabetes Genes

Kara Hunter, Dan Rainbow, Vincent Plagnol, John A. Todd, Laurence B. Peterson, Linda S. Wicker

J Immunol (2007) 179 (12): 8341–8349.

DOI: https://doi.org/10.4049/jimmunol.179.12.8341

Published: 15 December 2007

View article titled, Interactions between Idd5.1/Ctla4 and Other Type 1 Diabetes Genes

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Genetic Control of Autoimmunity: Protection from Diabetes, but Spontaneous Autoimmune Biliary Disease in a Nonobese Diabetic Congenic Strain

Syuichi Koarada, Yuehong Wu, Noreen Fertig, David A. Sass, Michael Nalesnik, John A. Todd, Paul A. Lyons, Judith Fenyk-Melody, Daniel B. Rainbow, Linda S. Wicker, Laurence B. Peterson, William M. Ridgway

J Immunol (2004) 173 (4): 2315–2323.

DOI: https://doi.org/10.4049/jimmunol.173.4.2315

Published: 15 August 2004

View article titled, Genetic Control of Autoimmunity: Protection from Diabetes, but Spontaneous Autoimmune Biliary Disease in a Nonobese Diabetic Congenic Strain

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Journal Articles

Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses Support Ctla4 and Nramp1 as Candidates for Idd5.1 and Idd5.2 in the Nonobese Diabetic Mouse

Linda S. Wicker, Giselle Chamberlain, Kara Hunter, Dan Rainbow, Sarah Howlett, Paul Tiffen, Jan Clark, Andrea Gonzalez-Munoz, Anne Marie Cumiskey, Raymond L. Rosa, Joanna M. Howson, Luc J. Smink, Amanda Kingsnorth, Paul A. Lyons, Simon Gregory, Jane Rogers, John A. Todd, Laurence B. Peterson

J Immunol (2004) 173 (1): 164–173.

DOI: https://doi.org/10.4049/jimmunol.173.1.164

Published: 01 July 2004

View article titled, Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses Support Ctla4 and Nramp1 as Candidates for Idd5.1 and Idd5.2 in the Nonobese Diabetic Mouse

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Journal Articles

New Genetic Loci That Control Susceptibility and Symptoms of Experimental Allergic Encephalomyelitis in Inbred Mice

Russell J. Butterfield, Jayce D. Sudweeks, Elizabeth P. Blankenhorn, Robert Korngold, Joseph C. Marini, John A. Todd, Randall J. Roper, Cory Teuscher

J Immunol (1998) 161 (4): 1860–1867.

DOI: https://doi.org/10.4049/jimmunol.161.4.1860

Published: 15 August 1998

View article titled, New Genetic Loci That Control Susceptibility and Symptoms of Experimental Allergic Encephalomyelitis in Inbred Mice

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NARROW

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Pillars Article: Genetic Analysis of Autoimmune Type 1 Diabetes Mellitus in Mice. Nature. 1991. 351: 542-547

Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors

Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4⁺CD25⁺ Regulatory T Cell Function

Identification of Cd101 as a Susceptibility Gene for Novosphingobium aromaticivorans-Induced Liver Autoimmunity

Evidence that Cd101 Is an Autoimmune Diabetes Gene in Nonobese Diabetic Mice

Nonobese Diabetic Congenic Strain Analysis of Autoimmune Diabetes Reveals Genetic Complexity of the Idd18 Locus and Identifies Vav3 as a Candidate Gene

NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese Diabetic Mice

Interactions between Idd5.1/Ctla4 and Other Type 1 Diabetes Genes

Genetic Control of Autoimmunity: Protection from Diabetes, but Spontaneous Autoimmune Biliary Disease in a Nonobese Diabetic Congenic Strain

Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses Support Ctla4 and Nramp1 as Candidates for Idd5.1 and Idd5.2 in the Nonobese Diabetic Mouse

New Genetic Loci That Control Susceptibility and Symptoms of Experimental Allergic Encephalomyelitis in Inbred Mice

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