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John C. Cambier
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Journal Articles

Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model

Scott M. Wemlinger, Chelsea R. Parker Harp, Bo Yu, Ian R. Hardy, Matthew Seefeldt, Jennifer Matsuda, Michael Mingueneau, Kerri A. Spilker, Thomas O. Cameron, James W. Larrick, Andrew Getahun, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2022) 208 (7): 1566–1584.
DOI: https://doi.org/10.4049/jimmunol.2101056
Published: 01 April 2022
View article titled, Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model
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Includes: Supplementary data
Journal Articles

The protective role of B cell anergy in the development of Atherosclerosis

Tayab Waseem, W. Coles Keeter, Alina Moriarty, Marion Mussbacher, Stefan Edemobi, Andrew Getahun, John C Cambier, Elena Galkina
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 71.13.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.71.13
Published: 01 May 2020
View article titled, The protective role of B cell anergy in the development of Atherosclerosis
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Journal Articles

Genetic contribution to loss of B cell anergy during development of autoimmunity

Mia J Smith, Marynette Rihanek, Zachary Stensland, Virginia Sarapura, Peter Gottlieb, John C Cambier
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 218.14.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.218.14
Published: 01 May 2020
View article titled, Genetic contribution to loss of B cell anergy during development of autoimmunity
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Journal Articles

A Precision B Cell–Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation

S. Elizabeth Franks, Andrew Getahun, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2019) 202 (12): 3381–3393.
DOI: https://doi.org/10.4049/jimmunol.1801394
Published: 15 June 2019
View article titled, A Precision B Cell–Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation
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Includes: Supplementary data
Journal Articles

BeO-exposure induces B cell-mediated Noninfectious Granuloma Formation in the Lung

Shaikh M Atif, Douglas Mack, Amy S McKee, Javier Rangel-Moreno, Allison K Martin, Andrew Getahun, Lisa A Maier, John C Cambier, Rubin M Tuder, Andrew P Fontenot
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 182.68.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.182.68
Published: 01 May 2019
View article titled, BeO-exposure induces B cell-mediated Noninfectious Granuloma Formation in the Lung
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Journal Articles

B cell anergy: Atheroprotective, yet vulnerable to atherosclerotic conditions

Tayab Waseem, William Coles Keeter, Alina Moriarty, Stefan Edemobi, Michael Pham, Andrew Getahun, John C Cambier, Elena Galkina
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 121.14.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.121.14
Published: 01 May 2019
View article titled, B cell anergy: Atheroprotective, yet vulnerable to atherosclerotic conditions
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Journal Articles

B Cell–Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses

Melissa M. Walker, Bergren W. Crute, John C. Cambier, Andrew Getahun
Journal: The Journal of Immunology
J Immunol (2018) 201 (9): 2641–2653.
DOI: https://doi.org/10.4049/jimmunol.1701405
Published: 01 November 2018
View article titled, B Cell–Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses
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Includes: Supplementary data
Journal Articles

Enforcing anergy of autoreactive B cells through inhibition of the PI3K pathway

S. Elizabeth Franks, Andrew Getahun, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 175.1.
DOI: https://doi.org/10.4049/jimmunol.200.Supp.175.1
Published: 01 May 2018
View article titled, Enforcing anergy of autoreactive B cells through inhibition of the PI3K pathway
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Journal Articles

B cell Intrinsic and Extrinsic Function of STING in the Antibody Response

Melissa Marie Walker, Bergren W Crute, Andrew Getahun, John C Cambier
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 199.15.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.199.15
Published: 01 May 2017
View article titled, B cell Intrinsic and Extrinsic Function of STING in the Antibody Response
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Journal Articles

Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines

Laura E. Noges, Janice White, John C. Cambier, John W. Kappler, Philippa Marrack
Journal: The Journal of Immunology
J Immunol (2016) 197 (4): 1221–1230.
DOI: https://doi.org/10.4049/jimmunol.1501565
Published: 15 August 2016
View article titled, Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines
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Includes: Supplementary data
Journal Articles

γδ T Cells Shape Preimmune Peripheral B Cell Populations

Yafei Huang, Andrew Getahun, Ryan A. Heiser, Thiago O. Detanico, Katja Aviszus, Greg A. Kirchenbaum, Tamara L. Casper, Chunjian Huang, M. Kemal Aydintug, Simon R. Carding, Koichi Ikuta, Hua Huang, Lawrence J. Wysocki, John C. Cambier, Rebecca L. O’Brien, Willi K. Born
Journal: The Journal of Immunology
J Immunol (2016) 196 (1): 217–231.
DOI: https://doi.org/10.4049/jimmunol.1501064
Published: 01 January 2016
View article titled, γδ T Cells Shape Preimmune Peripheral B Cell Populations
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Includes: Supplementary data
Journal Articles

Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination

Zhangguo Chen, Andrew Getahun, Xiaomi Chen, Yonatan Dollin, John C. Cambier, Jing H. Wang
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5461–5471.
DOI: https://doi.org/10.4049/jimmunol.1501375
Published: 01 December 2015
View article titled, Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination
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Journal Articles

Anti-CD79 Antibody Induces B Cell Anergy That Protects against Autoimmunity

Ian R. Hardy, Nadia Anceriz, François Rousseau, Matt B. Seefeldt, Eric Hatterer, Magali Irla, Vanessa Buatois, Laurence E. Chatel, Andrew Getahun, Ashley Fletcher, Laura Cons, Guillemette Pontini, Nicole A. Hertzberg, Giovanni Magistrelli, Pauline Malinge, Mia J. Smith, Walter Reith, Marie H. Kosco-Vilbois, Walter G. Ferlin, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2014) 192 (4): 1641–1650.
DOI: https://doi.org/10.4049/jimmunol.1302672
Published: 15 February 2014
View article titled, Anti-CD79 Antibody Induces B Cell Anergy That Protects against Autoimmunity
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Includes: Supplementary data
Journal Articles

STING/MPYS Mediates Host Defense against Listeria monocytogenes Infection by Regulating Ly6Chi Monocyte Migration

Lei Jin, Andrew Getahun, Heather M. Knowles, Jennifer Mogan, Linda J. Akerlund, Thomas A. Packard, Anne-Laure Perraud, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2835–2843.
DOI: https://doi.org/10.4049/jimmunol.1201788
Published: 15 March 2013
View article titled, STING/MPYS Mediates Host Defense against Listeria monocytogenes Infection by Regulating Ly6C<sup>hi</sup> Monocyte Migration
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Includes: Supplementary data
Journal Articles

Retention of Anergy and Inhibition of Antibody Responses during Acute Gammaherpesvirus 68 Infection

Andrew Getahun, Mia J. Smith, Igor Kogut, Linda F. van Dyk, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2965–2974.
DOI: https://doi.org/10.4049/jimmunol.1201407
Published: 15 September 2012
View article titled, Retention of Anergy and Inhibition of Antibody Responses during Acute Gammaherpesvirus 68 Infection
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Includes: Supplementary data
Journal Articles

VISA Is Required for B Cell Expression of TLR7

Liang-Guo Xu, Lei Jin, Bi-Cheng Zhang, Linda J. Akerlund, Hong-Bing Shu, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2012) 188 (1): 248–258.
DOI: https://doi.org/10.4049/jimmunol.1100918
Published: 01 January 2012
View article titled, VISA Is Required for B Cell Expression of TLR7
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Includes: Supplementary data
Journal Articles

MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP

Lei Jin, Krista K. Hill, Holly Filak, Jennifer Mogan, Heather Knowles, Bicheng Zhang, Anne-Laure Perraud, John C. Cambier, Laurel L. Lenz
Journal: The Journal of Immunology
J Immunol (2011) 187 (5): 2595–2601.
DOI: https://doi.org/10.4049/jimmunol.1100088
Published: 01 September 2011
View article titled, MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
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Includes: Supplementary data
Journal Articles

Establishing Anergy as a Bona Fide In Vivo Mechanism of B Cell Tolerance

In Special Collection:
Pillars of Immunology
Andrew Getahun, Shannon K. O'Neill, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2009) 183 (9): 5439–5441.
DOI: https://doi.org/10.4049/jimmunol.0990088
Published: 01 November 2009
View article titled, Establishing Anergy as a Bona Fide In Vivo Mechanism of B Cell Tolerance
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Journal Articles

TLR4-Mediated Signaling Induces MMP9-Dependent Cleavage of B Cell Surface CD23

Leila Jackson, Carol T. Cady, John C. Cambier
Journal: The Journal of Immunology
J Immunol (2009) 183 (4): 2585–2592.
DOI: https://doi.org/10.4049/jimmunol.0803660
Published: 15 August 2009
View article titled, TLR4-Mediated Signaling Induces MMP9-Dependent Cleavage of B Cell Surface CD23
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Includes: Supplementary data
Journal Articles

The immune adaptor MPYS/STING/MITA signals via multiple differentially regulated pathways (135.60)

lei jin, liang-guo xu, john c cambier
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 135.60.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.135.60
Published: 01 April 2009
View article titled, The immune adaptor MPYS/STING/MITA signals via multiple differentially regulated pathways (135.60)
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