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Lysosomal Protease Creation of Chimeric Epitopes for Diabetogenic CD4 T cells via Transpeptidation

Brendan Kearney Reed, Frances Crawford, Ryan Hill, Niyun Jin, Sai Harsha Krovi, Janice White, Philippa Marrack, Kirk Hansen, John Kappler

J Immunol (2020) 204 (1_Supplement): 217.11.

https://doi.org/10.4049/jimmunol.204.Supp.217.11

Published: 01 May 2020

View article titled, Lysosomal Protease Creation of Chimeric Epitopes for Diabetogenic CD4 T cells via Transpeptidation

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CD11c-expressing B cells from aged and autoimmune mice localize at T cell B cell border in spleen and present antigen more efficiently than Follicular B cells (BA3P.104)

Anatoly Rubtsov, Kira Rubtsova, John Kappler, Philippa Marrack

J Immunol (2015) 194 (1_Supplement): 46.1.

https://doi.org/10.4049/jimmunol.194.Supp.46.1

Published: 01 May 2015

View article titled, CD11c-expressing B cells from aged and autoimmune mice localize at T cell B cell border in spleen and present antigen more efficiently than Follicular B cells (BA3P.104)

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Paradigm-violating HLA class II-restricted CD8 T cells exist in HIV infected individuals (VIR6P.1164)

Srinika Ranasinghe, Pedro Lamothe, Soghioan Damien, Brad Jones, John Sidney, Alessandro Sette, Hendrik Streeck, Louis Picker, John Kappler, Daniel Kaufmann, Bruce Walker

J Immunol (2015) 194 (1_Supplement): 149.4.

https://doi.org/10.4049/jimmunol.194.Supp.149.4

Published: 01 May 2015

View article titled, Paradigm-violating HLA class II-restricted CD8 T cells exist in HIV infected individuals (VIR6P.1164)

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Characterizing the T cell receptor clonotype repertoire of an atypical HLA class II-restricted CD8 T cell response in HIV-1 infection (VIR6P.1170)

Pedro Lamothe, Srinika Ranasinghe, Frances Crawford, Janice White, Gina Clayton, Karen Power, Wilfredo Garcia-Beltran, Todd Allen, Alex Shalek, John Kappler, Bruce Walker

J Immunol (2015) 194 (1_Supplement): 149.10.

https://doi.org/10.4049/jimmunol.194.Supp.149.10

Published: 01 May 2015

View article titled, Characterizing the T cell receptor clonotype repertoire of an atypical HLA class II-restricted CD8 T cell response in HIV-1 infection (VIR6P.1170)

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Journal Articles

Host DNA released in response to aluminum adjuvant enhances MHCII mediated antigen presentation and prolongs CD4 T cell interactions with dendritic cells. (P4244)

Amy McKee, Matthew Burchill, Munks Michael, Lei Jin, John Kappler, Rachel Friedman, Jordan Jacobelli, Philippa Marrack

J Immunol (2013) 190 (1_Supplement): 47.10.

https://doi.org/10.4049/jimmunol.190.Supp.47.10

Published: 01 May 2013

View article titled, Host DNA released in response to aluminum adjuvant enhances MHCII mediated antigen presentation and prolongs CD4 T cell interactions with dendritic cells. (P4244)

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T-bet: a key player in a novel type of B cell activation essential for effective viral clearance (P4333)

Kira Rubtsova, Anatoly Rubtsov, John Kappler, Philippa Marrack

J Immunol (2013) 190 (1_Supplement): 183.2.

https://doi.org/10.4049/jimmunol.190.Supp.183.2

Published: 01 May 2013

View article titled, T-bet: a key player in a novel type of B cell activation essential for effective viral clearance (P4333)

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Characterizing the T cell receptor repertoire of beryllium-responsive CD4⁺ T cells (P5021)

Natalie Bowerman, Michael Falta, Douglas Mack, Frances Crawford, John Kappler, Andrew Fontenot

J Immunol (2013) 190 (1_Supplement): 110.11.

https://doi.org/10.4049/jimmunol.190.Supp.110.11

Published: 01 May 2013

View article titled, Characterizing the T cell receptor repertoire of beryllium-responsive CD4+ T cells (P5021)

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Journal Articles

MAIT cell recognition of MR1 bound by non-peptide antigen on bacterially infected and uninfected cells. (P5053)

Mary Young, Lance U'Ren, John Kappler, Philippa Marrack, Laurent Gapin

J Immunol (2013) 190 (1_Supplement): 111.9.

https://doi.org/10.4049/jimmunol.190.Supp.111.9

Published: 01 May 2013

View article titled, MAIT cell recognition of MR1 bound by non-peptide antigen on bacterially infected and uninfected cells. (P5053)

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A rapid method to isolate and test the γ2a switched variants from a γ2b antibody producing B cell hybridoma (P3382)

Haolin Liu, Gongyi Zhang, Philippa Marrack, John Kappler

J Immunol (2013) 190 (1_Supplement): 135.18.

https://doi.org/10.4049/jimmunol.190.Supp.135.18

Published: 01 May 2013

View article titled, A rapid method to isolate and test the γ2a switched variants from a γ2b antibody producing B cell hybridoma (P3382)

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Peptide vaccines prevent tumor growth by stimulating a similar T cell repertoire as the native tumor antigen (165.46)

Jill Slansky, Kimberly Jordan, Jonathan Buhrman, John Kappler, Jonathan Sprague, Brandon Moore, Dexiang Gao

J Immunol (2011) 186 (1_Supplement): 165.46.

https://doi.org/10.4049/jimmunol.186.Supp.165.46

Published: 01 April 2011

View article titled, Peptide vaccines prevent tumor growth by stimulating a similar T cell repertoire as the native tumor antigen (165.46)

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Journal Articles

Beryllium-specific T cells adopt an unusual binding topology for antigen recognition (100.25)

Natalie Bowerman, Michael Falta, Douglas Mack, John Kappler, Andrew Fontenot

J Immunol (2011) 186 (1_Supplement): 100.25.

https://doi.org/10.4049/jimmunol.186.Supp.100.25

Published: 01 April 2011

View article titled, Beryllium-specific T cells adopt an unusual binding topology for antigen recognition (100.25)

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T cells with a specific motif in the CDR3-beta region protect mice from CT26 tumor growth (131.46)

Jill Slansky, John Kappler, Brandon Moore, Carissa Dege, Nathan Pennock, Jonathan Sprague, Alexis Franks, Kimberly Jordan

J Immunol (2010) 184 (1_Supplement): 131.46.

https://doi.org/10.4049/jimmunol.184.Supp.131.46

Published: 01 April 2010

View article titled, T cells with a specific motif in the CDR3-beta region protect mice from CT26 tumor growth (131.46)

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Mapping TCR recognition of a beryllium antigen with implications for chronic beryllium disease (130.17)

Natalie Bowerman, Michael Falta, John Kappler, Andrew Fontenot

J Immunol (2010) 184 (1_Supplement): 130.17.

https://doi.org/10.4049/jimmunol.184.Supp.130.17

Published: 01 April 2010

View article titled, Mapping TCR recognition of a beryllium antigen with implications for chronic beryllium disease (130.17)

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Journal Articles

Sex hormone-independent capacities of female hematopoietic cells from lupus-prone mice (83.23)

Trine Jorgensen, Alexandria David, Megan MacLeod, Angela Johnson, John Kappler, Philippa Marrack

J Immunol (2010) 184 (1_Supplement): 83.23.

https://doi.org/10.4049/jimmunol.184.Supp.83.23

Published: 01 April 2010

View article titled, Sex hormone-independent capacities of female hematopoietic cells from lupus-prone mice (83.23)

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Journal Articles

Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.

John Kappler, Ralph Kubo, Kathryn Haskins, Charles Hannum, Philippa Marrack, Michele Pigeon, Bradley McIntyre, James Allison, Ian Trowbridge

J Immunol (2006) 176 (5): 2683–2690.

Published: 01 March 2006

View article titled, Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.

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Journal Articles

Presidential Address to The American Association of Immunologists : Major Histocompatibility Complex Proteins and TCRs: Do They Really Go Together Like a Horse and Carriage?

Philippa Marrack, Jeremy Bender, Michael Jordan, William Rees, Jennifer Robertson, Brian C. Schaefer, John Kappler

J Immunol (2001) 167 (2): 617–621.

https://doi.org/10.4049/jimmunol.167.2.617

Published: 15 July 2001

View article titled, Presidential Address to The American Association of Immunologists : <subtitle>Major Histocompatibility Complex Proteins and TCRs: Do They Really Go Together Like a Horse and Carriage?</subtitle>

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Journal Articles

Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue

Gilbert J. Kersh, Michael J. Miley, Christopher A. Nelson, Arash Grakoui, Stephen Horvath, David L. Donermeyer, John Kappler, Paul M. Allen, Daved H. Fremont

J Immunol (2001) 166 (5): 3345–3354.

https://doi.org/10.4049/jimmunol.166.5.3345

Published: 01 March 2001

View article titled, Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue

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Journal Articles

The Growth of the Very Large CD8⁺ T Cell Clones in Older Mice Is Controlled by Cytokines

Chia-Chi Ku, John Kappler, Philippa Marrack

J Immunol (2001) 166 (4): 2186–2193.

https://doi.org/10.4049/jimmunol.166.4.2186

Published: 15 February 2001

View article titled, The Growth of the Very Large CD8+ T Cell Clones in Older Mice Is Controlled by Cytokines

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Journal Articles

Bystander Virus Infection Prolongs Activated T Cell Survival

Tom Mitchell, John Kappler, Philippa Marrack

J Immunol (1999) 162 (8): 4527–4535.

https://doi.org/10.4049/jimmunol.162.8.4527

Published: 15 April 1999

View article titled, Bystander Virus Infection Prolongs Activated T Cell Survival

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Journal Articles

Soluble Class I MHC with β₂-Microglobulin Covalently Linked Peptides: Specific Binding to a T Cell Hybridoma

Janice White, Frances Crawford, Daved Fremont, Philippa Marrack, John Kappler

J Immunol (1999) 162 (5): 2671–2676.

https://doi.org/10.4049/jimmunol.162.5.2671

Published: 01 March 1999

View article titled, Soluble Class I MHC with β2-Microglobulin Covalently Linked Peptides: Specific Binding to a T Cell Hybridoma

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NARROW

Lysosomal Protease Creation of Chimeric Epitopes for Diabetogenic CD4 T cells via Transpeptidation

CD11c-expressing B cells from aged and autoimmune mice localize at T cell B cell border in spleen and present antigen more efficiently than Follicular B cells (BA3P.104)

Paradigm-violating HLA class II-restricted CD8 T cells exist in HIV infected individuals (VIR6P.1164)

Characterizing the T cell receptor clonotype repertoire of an atypical HLA class II-restricted CD8 T cell response in HIV-1 infection (VIR6P.1170)

Host DNA released in response to aluminum adjuvant enhances MHCII mediated antigen presentation and prolongs CD4 T cell interactions with dendritic cells. (P4244)

T-bet: a key player in a novel type of B cell activation essential for effective viral clearance (P4333)

Characterizing the T cell receptor repertoire of beryllium-responsive CD4⁺ T cells (P5021)

MAIT cell recognition of MR1 bound by non-peptide antigen on bacterially infected and uninfected cells. (P5053)

A rapid method to isolate and test the γ2a switched variants from a γ2b antibody producing B cell hybridoma (P3382)

Peptide vaccines prevent tumor growth by stimulating a similar T cell repertoire as the native tumor antigen (165.46)

Beryllium-specific T cells adopt an unusual binding topology for antigen recognition (100.25)

T cells with a specific motif in the CDR3-beta region protect mice from CT26 tumor growth (131.46)

Mapping TCR recognition of a beryllium antigen with implications for chronic beryllium disease (130.17)

Sex hormone-independent capacities of female hematopoietic cells from lupus-prone mice (83.23)

Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell 1983; 35: 295–302.

Presidential Address to The American Association of Immunologists : Major Histocompatibility Complex Proteins and TCRs: Do They Really Go Together Like a Horse and Carriage?

Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue

The Growth of the Very Large CD8⁺ T Cell Clones in Older Mice Is Controlled by Cytokines

Bystander Virus Infection Prolongs Activated T Cell Survival

Soluble Class I MHC with β₂-Microglobulin Covalently Linked Peptides: Specific Binding to a T Cell Hybridoma

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