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Anatomic Distribution of Intravenously Injected IgG Takes Approximately 1 Week to Achieve Stratum Corneum Saturation in Vaginal Tissues

Ann M. Carias, Jeffrey R. Schneider, Patrick Madden, Ramon Lorenzo-Redondo, Mariluz Araínga, Amarendra Pegu, Gianguido C. Cianci, Danijela Maric, Francois Villinger, John R. Mascola, Ronald S. Veazey, Thomas J. Hope

J Immunol (2021) 207 (2): 505–511.

https://doi.org/10.4049/jimmunol.2100253

Published: 15 July 2021

View article titled, Anatomic Distribution of Intravenously Injected IgG Takes Approximately 1 Week to Achieve Stratum Corneum Saturation in Vaginal Tissues

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Includes: Multimedia, Supplementary data

Journal Articles

Trispecific antibody against HIV-1 demonstrate anti-viral activity in vivo and have potent Fc-dependent effector functions

Cassandra Almasri, Ling Xu, Joana Dias, Wanwisa Promsote, Ronnie Wei, Dana M Lord, Ercole Rao, Jochen Beninga, Zhi-yong Yang, Amarendra Pegu, John R. Mascola, Gary J. Nabel

J Immunol (2020) 204 (1_Supplement): 167.6.

https://doi.org/10.4049/jimmunol.204.Supp.167.6

Published: 01 May 2020

View article titled, Trispecific antibody against HIV-1 demonstrate anti-viral activity in vivo and have potent Fc-dependent effector functions

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Tri-functional T-cell engagers target immune checkpoint inhibitors PD-1 and TIGIT to enhance CD8 effector T-cell functions in chronically SHIV-infected rhesus macaques

Wanwisa Promsote, David Ambrozak, Cassandra Almasri, Catherine Liu, Megan DeMouth, Jason Hataye, Amarendra Pegu, John R. Mascola, Richard Koup

J Immunol (2020) 204 (1_Supplement): 169.31.

https://doi.org/10.4049/jimmunol.204.Supp.169.31

Published: 01 May 2020

View article titled, Tri-functional T-cell engagers target immune checkpoint inhibitors PD-1 and TIGIT to enhance CD8 effector T-cell functions in chronically SHIV-infected rhesus macaques

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Journal Articles

HIV-1 gp120–CD4-Induced Antibody Complex Elicits CD4 Binding Site–Specific Antibody Response in Mice

Andrey Galkin, Yajing Chen, Javier Guenaga, Sijy O’Dell, Roderico Acevedo, James J. Steinhardt, Yimeng Wang, Richard Wilson, Chi-I Chiang, Nicole Doria-Rose, Alexander V. Grishaev, John R. Mascola, Yuxing Li

J Immunol (2020) 204 (6): 1543–1561.

https://doi.org/10.4049/jimmunol.1901051

Published: 15 March 2020

View article titled, HIV-1 gp120–CD4-Induced Antibody Complex Elicits CD4 Binding Site–Specific Antibody Response in Mice

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Includes: Supplementary data

Journal Articles

Passive infusion of Fc-modified neutralizing antibodies does not affect the dynamics of plasma virus decay in SHIV-infected macaques

Mangaiarkarasi Asokan, Anna Maximova, Joana Dias, Andrew R Crowley, Amarendra Pegu, David Ambrozak, Krisha McKee, Wei Shi, John-Paul Todd, Margaret E Ackerman, Lucio Gama, Brandon F Keele, Jeffrey D Lifson, Alan S Perelson, John R Mascola, Richard Koup

J Immunol (2019) 202 (1_Supplement): 72.6.

https://doi.org/10.4049/jimmunol.202.Supp.72.6

Published: 01 May 2019

View article titled, Passive infusion of Fc-modified neutralizing antibodies does not affect the dynamics of plasma virus decay in SHIV-infected macaques

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Journal Articles

An HIV-1 Env–Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes

Yajing Chen, Richard Wilson, Sijy O’Dell, Javier Guenaga, Yu Feng, Karen Tran, Chi-I Chiang, Heather E. Arendt, Joanne DeStefano, John R. Mascola, Richard T. Wyatt, Yuxing Li

J Immunol (2016) 197 (10): 3982–3998.

https://doi.org/10.4049/jimmunol.1601134

Published: 15 November 2016

View article titled, An HIV-1 Env–Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes

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Includes: Supplementary data

Journal Articles

High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Yimeng Wang, Christopher Sundling, Richard Wilson, Sijy O’Dell, Yajing Chen, Kaifan Dai, Ganesh E. Phad, Jiang Zhu, Yongli Xiao, John R. Mascola, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Yuxing Li

J Immunol (2016) 196 (9): 3729–3743.

https://doi.org/10.4049/jimmunol.1502543

Published: 01 May 2016

View article titled, High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

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Includes: Supplementary data

Journal Articles

Early prophylaxis impact for newborns at risk for HIV-1 transmission at birth: viral clearance and attenuation with neutralizing monoclonal antibodies in infant rhesus macaques

Ann Jones Hessell, Jonah B. Sacha, Christoph Kahl, Barney Graham, John R Mascola, Nancy L Haigwood

J Immunol (2016) 196 (1_Supplement): 146.18.

https://doi.org/10.4049/jimmunol.196.Supp.146.18

Published: 01 May 2016

View article titled, Early prophylaxis impact for newborns at risk for HIV-1 transmission at birth: viral clearance and attenuation with neutralizing monoclonal antibodies in infant rhesus macaques

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Journal Articles

Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization

Ganesh E. Phad, Néstor Vázquez Bernat, Yu Feng, Jidnyasa Ingale, Paola Andrea Martinez Murillo, Sijy O’Dell, Yuxing Li, John R. Mascola, Christopher Sundling, Richard T. Wyatt, Gunilla B. Karlsson Hedestam

J Immunol (2015) 194 (12): 5903–5914.

https://doi.org/10.4049/jimmunol.1500122

Published: 15 June 2015

View article titled, Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization

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Includes: Supplementary data

Journal Articles

Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

Christopher Sundling, Zhenhai Zhang, Ganesh E. Phad, Zizhang Sheng, Yimeng Wang, John R. Mascola, Yuxing Li, Richard T. Wyatt, Lawrence Shapiro, Gunilla B. Karlsson Hedestam

J Immunol (2014) 192 (8): 3637–3644.

https://doi.org/10.4049/jimmunol.1303334

Published: 15 April 2014

View article titled, Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

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Includes: Supplementary data

Journal Articles

Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

Ivelin S. Georgiev, Rebecca S. Rudicell, Kevin O. Saunders, Wei Shi, Tatsiana Kirys, Krisha McKee, Sijy O’Dell, Gwo-Yu Chuang, Zhi-Yong Yang, Gilad Ofek, Mark Connors, John R. Mascola, Gary J. Nabel, Peter D. Kwong

J Immunol (2014) 192 (3): 1100–1106.

https://doi.org/10.4049/jimmunol.1302515

Published: 01 February 2014

View article titled, Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

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Journal Articles

Anti-HIV B Cell Lines as Candidate Vaccine Biosensors

J Immunol (2012) 189 (10): 4816–4824.

https://doi.org/10.4049/jimmunol.1202165

Published: 15 November 2012

View article titled, Anti-HIV B Cell Lines as Candidate Vaccine Biosensors

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Includes: Supplementary data

Journal Articles

BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses

Pia Dosenovic, Martina Soldemo, Jean L. Scholz, Sijy O’Dell, Emilie K. Grasset, Nadège Pelletier, Mikael C. I. Karlsson, John R. Mascola, Richard T. Wyatt, Michael P. Cancro, Gunilla B. Karlsson Hedestam

J Immunol (2012) 188 (12): 6018–6026.

https://doi.org/10.4049/jimmunol.1200466

Published: 15 June 2012

View article titled, BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses

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Includes: Supplementary data

Journal Articles

Preservation of Functional Virus-Specific Memory CD8⁺ T Lymphocytes in Vaccinated, Simian Human Immunodeficiency Virus-Infected Rhesus Monkeys

Paula M. Acierno, Jörn E. Schmitz, Darci A. Gorgone, Yue Sun, Sampa Santra, Michael S. Seaman, Michael H. Newberg, John R. Mascola, Gary J. Nabel, Dennis Panicali, Norman L. Letvin

J Immunol (2006) 176 (9): 5338–5345.

https://doi.org/10.4049/jimmunol.176.9.5338

Published: 01 May 2006

View article titled, Preservation of Functional Virus-Specific Memory CD8<sup>+</sup> T Lymphocytes in Vaccinated, Simian Human Immunodeficiency Virus-Infected Rhesus Monkeys

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Journal Articles

Dysfunction of Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus-Induced IL-2 Expression by Central Memory CD4⁺ T Lymphocytes

Yue Sun, Jörn E. Schmitz, Paula M. Acierno, Sampa Santra, Ramu A. Subbramanian, Dan H. Barouch, Darci A. Gorgone, Michelle A. Lifton, Kristin R. Beaudry, Kelledy Manson, Valerie Philippon, Ling Xu, Holden T. Maecker, John R. Mascola, Dennis Panicali, Gary J. Nabel, Norman L. Letvin

J Immunol (2005) 174 (8): 4753–4760.

https://doi.org/10.4049/jimmunol.174.8.4753

Published: 15 April 2005

View article titled, Dysfunction of Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus-Induced IL-2 Expression by Central Memory CD4<sup>+</sup> T Lymphocytes

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Journal Articles

HIV-1 Neutralizing Antibodies in the Genital and Respiratory Tracts of Mice Intranasally Immunized with Oligomeric gp160

Thomas C. VanCott, Robert W. Kaminski, John R. Mascola, Vaniambadi S. Kalyanaraman, Nabila M. Wassef, Carl R. Alving, J.Terry Ulrich, George H. Lowell, Deborah L. Birx

J Immunol (1998) 160 (4): 2000–2012.

https://doi.org/10.4049/jimmunol.160.4.2000

Published: 15 February 1998

View article titled, HIV-1 Neutralizing Antibodies in the Genital and Respiratory Tracts of Mice Intranasally Immunized with Oligomeric gp160

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NARROW

Anatomic Distribution of Intravenously Injected IgG Takes Approximately 1 Week to Achieve Stratum Corneum Saturation in Vaginal Tissues

Trispecific antibody against HIV-1 demonstrate anti-viral activity in vivo and have potent Fc-dependent effector functions

Tri-functional T-cell engagers target immune checkpoint inhibitors PD-1 and TIGIT to enhance CD8 effector T-cell functions in chronically SHIV-infected rhesus macaques

HIV-1 gp120–CD4-Induced Antibody Complex Elicits CD4 Binding Site–Specific Antibody Response in Mice

Passive infusion of Fc-modified neutralizing antibodies does not affect the dynamics of plasma virus decay in SHIV-infected macaques

An HIV-1 Env–Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes

High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Early prophylaxis impact for newborns at risk for HIV-1 transmission at birth: viral clearance and attenuation with neutralizing monoclonal antibodies in infant rhesus macaques

Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization

Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

Anti-HIV B Cell Lines as Candidate Vaccine Biosensors

BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses

Preservation of Functional Virus-Specific Memory CD8⁺ T Lymphocytes in Vaccinated, Simian Human Immunodeficiency Virus-Infected Rhesus Monkeys

Dysfunction of Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus-Induced IL-2 Expression by Central Memory CD4⁺ T Lymphocytes

HIV-1 Neutralizing Antibodies in the Genital and Respiratory Tracts of Mice Intranasally Immunized with Oligomeric gp160

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