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John T. Harty
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Journal Articles

Defining Parameters That Modulate Susceptibility and Protection to Respiratory Murine Coronavirus MHV1 Infection

Elvia E. Silva, Steven J. Moioffer, Mariah Hassert, Roger R. Berton, Matthew G. Smith, Stephanie van de Wall, David K. Meyerholz, Thomas S. Griffith, John T. Harty, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2024) 212 (4): 563–575.
https://doi.org/10.4049/jimmunol.2300434
Published: 27 December 2023
View article titled, Defining Parameters That Modulate Susceptibility and Protection to Respiratory Murine Coronavirus MHV1 Infection
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Includes: Supplementary data
Journal Articles

Acute and chronic viral infection generate brain-resident memory T cells with distinct phenotypic, functional, spatial, and metabolic profiles

Madison R. Mix, Lecia L Epping, Lisa S Hancox, Ronald A Merrill, Eric B Taylor, Vladimir P Badovinac, John T Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 59.02.
https://doi.org/10.4049/jimmunol.210.Supp.59.02
Published: 01 May 2023
View article titled, Acute and chronic viral infection generate brain-resident memory T cells with distinct phenotypic, functional, spatial, and metabolic profiles
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Journal Articles

Imaging of lung resident memory CD8 +T cells reveals antigen-specific early protective responses during secondary infection

Stephanie van de Wall, Scott M. Anthony, Steven M. Varga, Ryan A. Langlois, Dietmar Zehn, Vladimir P. Badovinac, John T. Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 236.13.
https://doi.org/10.4049/jimmunol.210.Supp.236.13
Published: 01 May 2023
View article titled, Imaging of lung resident memory CD8 <sup>+</sup>T cells reveals antigen-specific early protective responses during secondary infection
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Journal Articles

Radiation causes long term changes in virus-specific and virtual memory CD4 T cells

Shravan Kumar Kannan, Mohammad Heidarian, Whitney Swanson, Thomas S Griffith, John T Harty, Vladimir P Badovinac
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 76.05.
https://doi.org/10.4049/jimmunol.210.Supp.76.05
Published: 01 May 2023
View article titled, Radiation causes long term changes in virus-specific and virtual memory CD4 T cells
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Journal Articles

Defining parameters that influence susceptibility and protection to murine respiratory beta-coronavirus MHV-1 infection

Elvia E Silva, Steven Moioffer, Stephanie Van De Wall, Roger Berton, David Meyerholz, John T Harty, Vladimir Badovinac
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 75.42.
https://doi.org/10.4049/jimmunol.210.Supp.75.42
Published: 01 May 2023
View article titled, Defining parameters that influence susceptibility and protection to murine respiratory beta-coronavirus MHV-1 infection
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Journal Articles

Ionizing radiation induces lasting changes to the tissue resident memory T cell compartment

Mariah Hassert, Mohammad Heidarian, Vladimir P Badovinac, John T Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 156.10.
https://doi.org/10.4049/jimmunol.210.Supp.156.10
Published: 01 May 2023
View article titled, Ionizing radiation induces lasting changes to the tissue resident memory T cell compartment
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Journal Articles

Sublethal whole-body irradiation induces permanent loss and dysfunction in pre-existing pathogen-specific memory CD8 T cell populations

Mohammad Heidarian, Isaac J. Jensen, Mariah Hassert, Shravan Kumar Kannan, Hai-Hui Xue, John T. Harty, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 239.18.
https://doi.org/10.4049/jimmunol.210.Supp.239.18
Published: 01 May 2023
View article titled, Sublethal whole-body irradiation induces permanent loss and dysfunction in pre-existing pathogen-specific memory CD8 T cell populations
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Journal Articles

CD4 T Cell–Dependent and –Independent Roles for IFN-γ in Blood-Stage Malaria

Lisa L. Drewry, Lecia L. Pewe, Lisa S. Hancox, Stephanie Van de Wall, John T. Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (9): 1305–1313.
https://doi.org/10.4049/jimmunol.2200899
Published: 20 March 2023
View article titled, CD4 T Cell–Dependent and –Independent Roles for IFN-γ in Blood-Stage Malaria
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Journal Articles

Cutting Edge: Influenza-Induced CD11alo Airway CD103+ Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation

Stephanie van de Wall, Sequoia Crooks, Steven M. Varga, Vladimir P. Badovinac, John T. Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1025–1030.
https://doi.org/10.4049/jimmunol.2200931
Published: 13 March 2023
View article titled, Cutting Edge: Influenza-Induced CD11a<sup>lo</sup> Airway CD103<sup>+</sup> Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation
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Includes: Supplementary data
Journal Articles

Alveolar macrophages act as an early viral sponge inducing long-lived functional enhancement

Kody Waldstein, Stephanie van de Wall, Scott Anthony, John T Harty, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 126.05.
https://doi.org/10.4049/jimmunol.208.Supp.126.05
Published: 01 May 2022
View article titled, Alveolar macrophages act as an early viral sponge inducing long-lived functional enhancement
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Journal Articles

Cutting Edge: Subunit Booster Vaccination Confers Sterilizing Immunity against Liver-Stage Malaria in Mice Initially Primed with a Weight-Normalized Dose of Radiation-Attenuated Sporozoites

Mitchell N. Lefebvre, Lisa L. Drewry, Lecia L. Pewe, Lisa S. Hancox, Arturo Reyes-Sandoval, John T. Harty
Journal: The Journal of Immunology
J Immunol (2021) 207 (11): 2631–2635.
https://doi.org/10.4049/jimmunol.2100818
Published: 01 December 2021
View article titled, Cutting Edge: Subunit Booster Vaccination Confers Sterilizing Immunity against Liver-Stage Malaria in Mice Initially Primed with a Weight-Normalized Dose of Radiation-Attenuated Sporozoites
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Includes: Supplementary data
Journal Articles

Severity of Sepsis Determines the Degree of Impairment Observed in Circulatory and Tissue-Resident Memory CD8 T Cell Populations

Steven J. Moioffer, Derek B. Danahy, Stephanie van de Wall, Isaac J. Jensen, Frances V. Sjaastad, Scott M. Anthony, John T. Harty, Thomas S. Griffith, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2021) 207 (7): 1871–1881.
https://doi.org/10.4049/jimmunol.2001142
Published: 01 October 2021
View article titled, Severity of Sepsis Determines the Degree of Impairment Observed in Circulatory and Tissue-Resident Memory CD8 T Cell Populations
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Includes: Supplementary data
Journal Articles

NK Cell–Derived IL-10 Supports Host Survival during Sepsis

Isaac J. Jensen, Patrick W. McGonagill, Noah S. Butler, John T. Harty, Thomas S. Griffith, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2021) 206 (6): 1171–1180.
https://doi.org/10.4049/jimmunol.2001131
Published: 15 March 2021
View article titled, NK Cell–Derived IL-10 Supports Host Survival during Sepsis
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Includes: Supplementary data
Journal Articles

p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In Vivo

Samarchith P. Kurup, Steven J. Moioffer, Lecia L. Pewe, John T. Harty
Journal: The Journal of Immunology
J Immunol (2020) 205 (8): 2222–2230.
https://doi.org/10.4049/jimmunol.2000654
Published: 15 October 2020
View article titled, p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In Vivo
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Includes: Supplementary data
Journal Articles

Diverse CD8 T cell responses to infection revealed by the collaborative cross

Matthew D Martin, Ramakrishna Sompallae, Christina Winborn, John T Harty, Vladimir P Badovinac
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 95.16.
https://doi.org/10.4049/jimmunol.204.Supp.95.16
Published: 01 May 2020
View article titled, Diverse CD8 T cell responses to infection revealed by the collaborative cross
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Journal Articles

Peripherally-induced brain tissue resident memory CD8 T cells mediate protection against CNS infections

Stina Lisa Urban, Isaac J Jensen, Lecia L Pewe, Vladimir P Badovinac, John T Harty
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 144.15.
https://doi.org/10.4049/jimmunol.204.Supp.144.15
Published: 01 May 2020
View article titled, Peripherally-induced brain tissue resident memory CD8 T cells mediate protection against CNS infections
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Journal Articles

Resident memory CD8 T cells patrol the lung and mediate early protective immunity

Scott M Anthony, Ryan A Langlois, Steven M Varga, John T Harty
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 85.1.
https://doi.org/10.4049/jimmunol.204.Supp.85.1
Published: 01 May 2020
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Journal Articles

Sepsis-Induced State of Immunoparalysis Is Defined by Diminished CD8 T Cell–Mediated Antitumor Immunity

Derek B. Danahy, Samarchith P. Kurup, Christina S. Winborn, Isaac J. Jensen, John T. Harty, Thomas S. Griffith, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2019) 203 (3): 725–735.
https://doi.org/10.4049/jimmunol.1900435
Published: 01 August 2019
View article titled, Sepsis-Induced State of Immunoparalysis Is Defined by Diminished CD8 T Cell–Mediated Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Peripherally induced tissue resident memory CD8 T cells in the brain mediate protection against CNS infections

Stina Lisa Urban, Isaac J Jensen, Lecia L. Pewe, Vladimir P Badovinac, John T Harty
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 117.4.
https://doi.org/10.4049/jimmunol.202.Supp.117.4
Published: 01 May 2019
View article titled, Peripherally induced tissue resident memory CD8 T cells in the brain mediate protection against CNS infections
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Journal Articles

Neuroantigen-specific regulatory CD8+ T cell responses as a therapy for relapsing autoimmune demyelinating disease

Ashley A Brate, Farah R. Itani, Lecia L. Pewe, John T Harty, Nitin J. Karandikar
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 193.11.
https://doi.org/10.4049/jimmunol.202.Supp.193.11
Published: 01 May 2019
View article titled, Neuroantigen-specific regulatory CD8+ T cell responses as a therapy for relapsing autoimmune demyelinating disease
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