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Jonathon D. Sedgwick
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Journal Articles

Loss of TNF Signaling Facilitates the Development of a Novel Ly-6Clow Macrophage Population Permissive for Leishmania major Infection

Phillip D. Fromm, Jessica Kling, Matthias Mack, Jonathon D. Sedgwick, Heinrich Körner
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6258–6266.
https://doi.org/10.4049/jimmunol.1100977
Published: 15 June 2012
View article titled, Loss of TNF Signaling Facilitates the Development of a Novel Ly-6C<sup>low</sup> Macrophage Population Permissive for <em>Leishmania major</em> Infection
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Differential Requirements by CD4+ and CD8+ T Cells for Soluble and Membrane TNF in Control of Francisella tularensis Live Vaccine Strain Intramacrophage Growth

Siobhán C. Cowley, Jonathon D. Sedgwick, Karen L. Elkins
Journal: The Journal of Immunology
J Immunol (2007) 179 (11): 7709–7719.
https://doi.org/10.4049/jimmunol.179.11.7709
Published: 01 December 2007
View article titled, Differential Requirements by CD4<sup>+</sup> and CD8<sup>+</sup> T Cells for Soluble and Membrane TNF in Control of <em>Francisella tularensis</em> Live Vaccine Strain Intramacrophage Growth
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TNF Is Important for Pathogen Control and Limits Brain Damage in Murine Cerebral Listeriosis

Simona Virna, Martina Deckert, Sonja Lütjen, Sabine Soltek, Kathryn E. Foulds, Hao Shen, Heinrich Körner, Jonathon D. Sedgwick, Dirk Schlüter
Journal: The Journal of Immunology
J Immunol (2006) 177 (6): 3972–3982.
https://doi.org/10.4049/jimmunol.177.6.3972
Published: 15 September 2006
View article titled, TNF Is Important for Pathogen Control and Limits Brain Damage in Murine Cerebral Listeriosis
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Journal Articles

Mast Cell-Associated TNF Promotes Dendritic Cell Migration

Hajime Suto, Susumu Nakae, Maki Kakurai, Jonathon D. Sedgwick, Mindy Tsai, Stephen J. Galli
Journal: The Journal of Immunology
J Immunol (2006) 176 (7): 4102–4112.
https://doi.org/10.4049/jimmunol.176.7.4102
Published: 01 April 2006
View article titled, Mast Cell-Associated TNF Promotes Dendritic Cell Migration
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Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice

Seng-Lai Tan, Jingyong Zhao, Chen Bi, XinYi Cynthia Chen, Deena L. Hepburn, Jian Wang, Jonathon D. Sedgwick, Subba R. Chintalacharuvu, Songqing Na
Journal: The Journal of Immunology
J Immunol (2006) 176 (5): 2872–2879.
https://doi.org/10.4049/jimmunol.176.5.2872
Published: 01 March 2006
View article titled, Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice
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Journal Articles

Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF

Susumu Nakae, Hajime Suto, Motoyasu Iikura, Maki Kakurai, Jonathon D. Sedgwick, Mindy Tsai, Stephen J. Galli
Journal: The Journal of Immunology
J Immunol (2006) 176 (4): 2238–2248.
https://doi.org/10.4049/jimmunol.176.4.2238
Published: 15 February 2006
View article titled, Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF
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Journal Articles

Regulation of Myeloid Cell Function through the CD200 Receptor

Maria C. Jenmalm, Holly Cherwinski, Edward P. Bowman, Joseph H. Phillips, Jonathon D. Sedgwick
Journal: The Journal of Immunology
J Immunol (2006) 176 (1): 191–199.
https://doi.org/10.4049/jimmunol.176.1.191
Published: 01 January 2006
View article titled, Regulation of Myeloid Cell Function through the CD200 Receptor
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Journal Articles

Transmembrane TNF Is Sufficient to Initiate Cell Migration and Granuloma Formation and Provide Acute, but Not Long-Term, Control of Mycobacterium tuberculosis Infection

Bernadette M. Saunders, Stephen Tran, Sigrid Ruuls, Jonathon D. Sedgwick, Helen Briscoe, Warwick J. Britton
Journal: The Journal of Immunology
J Immunol (2005) 174 (8): 4852–4859.
https://doi.org/10.4049/jimmunol.174.8.4852
Published: 15 April 2005
View article titled, Transmembrane TNF Is Sufficient to Initiate Cell Migration and Granuloma Formation and Provide Acute, but Not Long-Term, Control of <em>Mycobacterium tuberculosis</em> Infection
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Journal Articles

Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge.

Neil Taylor, Karen McConnachie, Claudia Calder, Rosemary Dawson, Andrew Dick, Jonathon D. Sedgwick, Janet Liversidge
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3818.
https://doi.org/10.4049/jimmunol.174.6.3818-c
Published: 15 March 2005
View article titled, Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge.
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Journal Articles

Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge

Neil Taylor, Karen McConnachie, Claudia Calder, Rosemary Dawson, Andrew Dick, Jonathon D. Sedgwick, Janet Liversidge
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 143–154.
https://doi.org/10.4049/jimmunol.174.1.143
Published: 01 January 2005
View article titled, Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge
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Journal Articles

Molecular Mechanisms of CD200 Inhibition of Mast Cell Activation

Shuli Zhang, Holly Cherwinski, Jonathon D. Sedgwick, Joseph H. Phillips
Journal: The Journal of Immunology
J Immunol (2004) 173 (11): 6786–6793.
https://doi.org/10.4049/jimmunol.173.11.6786
Published: 01 December 2004
View article titled, Molecular Mechanisms of CD200 Inhibition of Mast Cell Activation
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A Novel Model for Lymphocytic Infiltration of the Thyroid Gland Generated by Transgenic Expression of the CC Chemokine CCL21

Andrea P. Martin, Elizabeth C. Coronel, Gen-ichiro Sano, Shu-Cheng Chen, Galya Vassileva, Claudia Canasto-Chibuque, Jonathon D. Sedgwick, Paul S. Frenette, Martin Lipp, Glaucia C. Furtado, Sergio A. Lira
Journal: The Journal of Immunology
J Immunol (2004) 173 (8): 4791–4798.
https://doi.org/10.4049/jimmunol.173.8.4791
Published: 15 October 2004
View article titled, A Novel Model for Lymphocytic Infiltration of the Thyroid Gland Generated by Transgenic Expression of the CC Chemokine CCL21
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Journal Articles

Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200

Gavin J. Wright, Holly Cherwinski, Mildred Foster-Cuevas, Gary Brooke, Michael J. Puklavec, Mike Bigler, Yaoli Song, Maria Jenmalm, Dan Gorman, Terri McClanahan, Man-Ru Liu, Marion H. Brown, Jonathon D. Sedgwick, Joseph H. Phillips, A. Neil Barclay
Journal: The Journal of Immunology
J Immunol (2003) 171 (6): 3034–3046.
https://doi.org/10.4049/jimmunol.171.6.3034
Published: 15 September 2003
View article titled, Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200
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Journal Articles

Interactions Between Hemopoietically Derived TNF and Central Nervous System-Resident Glial Chemokines Underlie Initiation of Autoimmune Inflammation in the Brain

Craig A. Murphy, Robert M. Hoek, Maria T. Wiekowski, Sergio A. Lira, Jonathon D. Sedgwick
Journal: The Journal of Immunology
J Immunol (2002) 169 (12): 7054–7062.
https://doi.org/10.4049/jimmunol.169.12.7054
Published: 15 December 2002
View article titled, Interactions Between Hemopoietically Derived TNF and Central Nervous System-Resident Glial Chemokines Underlie Initiation of Autoimmune Inflammation in the Brain
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Cutting Edge: Organogenesis of Nasal-Associated Lymphoid Tissue (NALT) Occurs Independently of Lymphotoxin-α (LTα) and Retinoic Acid Receptor-Related Orphan Receptor-γ, but the Organization of NALT Is LTα Dependent

Allen Harmsen, Kimberley Kusser, Louise Hartson, Michael Tighe, Mary Jean Sunshine, Jonathon D. Sedgwick, Yongwon Choi, Dan R. Littman, Troy D. Randall
Journal: The Journal of Immunology
J Immunol (2002) 168 (3): 986–990.
https://doi.org/10.4049/jimmunol.168.3.986
Published: 01 February 2002
View article titled, Cutting Edge: Organogenesis of Nasal-Associated Lymphoid Tissue (NALT) Occurs Independently of Lymphotoxin-α (LTα) and Retinoic Acid Receptor-Related Orphan Receptor-γ, but the Organization of NALT Is LTα Dependent
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Adenovirus-Induced Liver Pathology Is Mediated Through TNF Receptors I and II but Is Independent of TNF or Lymphotoxin

Hikmat Hayder, Robert V. Blanden, Heinrich Körner, D. Sean Riminton, Jonathon D. Sedgwick, Arno Müllbacher
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1516–1520.
https://doi.org/10.4049/jimmunol.163.3.1516
Published: 01 August 1999
View article titled, Adenovirus-Induced Liver Pathology Is Mediated Through TNF Receptors I and II but Is Independent of TNF or Lymphotoxin
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Journal Articles

Multiple Deficiencies Underlie NK Cell Inactivity in Lymphotoxin-α Gene-Targeted Mice

Mark J. Smyth, Ricky W. Johnstone, Erika Cretney, Nicole M. Haynes, Jonathon D. Sedgwick, Heiner Korner, Lynn D. Poulton, Alan G. Baxter
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1350–1353.
https://doi.org/10.4049/jimmunol.163.3.1350
Published: 01 August 1999
View article titled, Multiple Deficiencies Underlie NK Cell Inactivity in Lymphotoxin-α Gene-Targeted Mice
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Structural Deficiencies in Granuloma Formation in TNF Gene-Targeted Mice Underlie the Heightened Susceptibility to Aerosol Mycobacterium tuberculosis Infection, Which Is Not Compensated for by Lymphotoxin

Andrew G. D. Bean, Daniel R. Roach, Helen Briscoe, Malcolm P. France, Heinrich Korner, Jonathon D. Sedgwick, Warwick J. Britton
Journal: The Journal of Immunology
J Immunol (1999) 162 (6): 3504–3511.
https://doi.org/10.4049/jimmunol.162.6.3504
Published: 15 March 1999
View article titled, Structural Deficiencies in Granuloma Formation in TNF Gene-Targeted Mice Underlie the Heightened Susceptibility to Aerosol <em>Mycobacterium tuberculosis</em> Infection, Which Is Not Compensated for by Lymphotoxin
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Journal Articles

TNF/Lymphotoxin-α Double-Mutant Mice Resist Septic Arthritis but Display Increased Mortality in Response to Staphylococcus aureus

Olof Hultgren, Hans-Pietro Eugster, Jonathon D. Sedgwick, Heinrich Körner, Andrzej Tarkowski
Journal: The Journal of Immunology
J Immunol (1998) 161 (11): 5937–5942.
https://doi.org/10.4049/jimmunol.161.11.5937
Published: 01 December 1998
View article titled, TNF/Lymphotoxin-α Double-Mutant Mice Resist Septic Arthritis but Display Increased Mortality in Response to <em>Staphylococcus aureus</em>
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Central Nervous System Microglial Cell Activation and Proliferation Follows Direct Interaction with Tissue-Infiltrating T Cell Blasts

Jonathon D. Sedgwick, Andrew L. Ford, Eléna Foulcher, Rhonda Airriess
Journal: The Journal of Immunology
J Immunol (1998) 160 (11): 5320–5330.
https://doi.org/10.4049/jimmunol.160.11.5320
Published: 01 June 1998
View article titled, Central Nervous System Microglial Cell Activation and Proliferation Follows Direct Interaction with Tissue-Infiltrating T Cell Blasts
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