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Juan Carlos Zúñiga-Pflücker
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Journal Articles

Epidermal ADAM17 provides barrier immunity and prevents myeloproliferative disease by regulating Notch-AP1 interaction (166.7)

Aditya Murthy, Yang Washington Shao, Juan Guinea-Viniegra, Swami Narala, Juan Carlos Zúñiga-Pflücker, Erwin Wagner, Rama Khokha
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 166.7.
https://doi.org/10.4049/jimmunol.186.Supp.166.7
Published: 01 April 2011
View article titled, Epidermal ADAM17 provides barrier immunity and prevents myeloproliferative disease by regulating Notch-AP1 interaction (166.7)
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Journal Articles

Notch signaling requires GATA-3 for the survival of cells entering the T-lineage development program (64.4)

Patrycja Thompson, Renée de Pooter, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 64.4.
https://doi.org/10.4049/jimmunol.186.Supp.64.4
Published: 01 April 2011
View article titled, Notch signaling requires GATA-3 for the survival of cells entering the T-lineage development program (64.4)
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Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lympho-myeloid lineage commitment outcomes (36.27)

Mahmood Mohtashami, Divya Shah, Hiroshi Nakase, Korosh Kianizad, Howard Petrie, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 36.27.
https://doi.org/10.4049/jimmunol.184.Supp.36.27
Published: 01 April 2010
View article titled, Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lympho-myeloid lineage commitment outcomes (36.27)
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Journal Articles

The Original Intrathymic Progenitor from Which T Cells Originate

In Special Collection:
Pillars of Immunology
Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2009) 183 (1): 3–4.
https://doi.org/10.4049/jimmunol.0990043
Published: 01 July 2009
View article titled, The Original Intrathymic Progenitor from Which T Cells Originate
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Journal Articles

TLR Ligand-Induced Type I IFNs Affect Thymopoiesis

Marie-Laurence Baron, Dominique Gauchat, Ross La Motte-Mohs, Nadia Kettaf, Ali Abdallah, Thomas Michiels, Juan-Carlos Zúñiga-Pflücker, Rafick-Pierre Sékaly
Journal: The Journal of Immunology
J Immunol (2008) 180 (11): 7134–7146.
https://doi.org/10.4049/jimmunol.180.11.7134
Published: 01 June 2008
View article titled, TLR Ligand-Induced Type I IFNs Affect Thymopoiesis
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Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint

Ekaterina K. Koltsova, Maria Ciofani, Robert Benezra, Toru Miyazaki, Neil Clipstone, Juan Carlos Zúñiga-Pflücker, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2007) 179 (7): 4694–4703.
https://doi.org/10.4049/jimmunol.179.7.4694
Published: 01 October 2007
View article titled, Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint
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Journal Articles

New Sequence of Strategies to Define Gene Transcriptional Territories in Lymphocytes: The Perforin Example (35.32)

Mathias Georg Lichtenheld, Juan Carlos Zúñiga-Pflücker, Anjana Rao, Matthew E. Pipkin
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S7–S8.
https://doi.org/10.4049/jimmunol.178.Supp.35.32
Published: 01 April 2007
View article titled, New Sequence of Strategies to Define Gene Transcriptional Territories in Lymphocytes: The Perforin Example (35.32)
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A Natural Structural Variant of the Mouse TCR β-Chain Displays Intrinsic Receptor Function and Antigen Specificity

Anne Aublin, Maria Ciofani, Nancy Willkomm, Abdelbasset Hamrouni, Andrea L. Szymczak-Workman, Tomio Takahashi, Yongoua Sandjeu, Philippe Guillaume, Dario A. A. Vignali, Olivier Michielin, Juan Carlos Zúñiga-Pflücker, Janet L. Maryanski
Journal: The Journal of Immunology
J Immunol (2006) 177 (12): 8587–8594.
https://doi.org/10.4049/jimmunol.177.12.8587
Published: 15 December 2006
View article titled, A Natural Structural Variant of the Mouse TCR β-Chain Displays Intrinsic Receptor Function and Antigen Specificity
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Journal Articles

The Basic Helix-Loop-Helix Transcription Factor HEBAlt Is Expressed in Pro-T Cells and Enhances the Generation of T Cell Precursors

Duncheng Wang, Carol L. Claus, Giovanna Vaccarelli, Marsela Braunstein, Thomas M. Schmitt, Juan Carlos Zúñiga-Pflücker, Ellen V. Rothenberg, Michele K. Anderson
Journal: The Journal of Immunology
J Immunol (2006) 177 (1): 109–119.
https://doi.org/10.4049/jimmunol.177.1.109
Published: 01 July 2006
View article titled, The Basic Helix-Loop-Helix Transcription Factor HEBAlt Is Expressed in Pro-T Cells and Enhances the Generation of T Cell Precursors
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Journal Articles

Notch Signaling Requires GATA-2 to Inhibit Myelopoiesis from Embryonic Stem Cells and Primary Hemopoietic Progenitors

Renée F. de Pooter, Thomas M. Schmitt, José Luis de la Pompa, Yuko Fujiwara, Stuart H. Orkin, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2006) 176 (9): 5267–5275.
https://doi.org/10.4049/jimmunol.176.9.5267
Published: 01 May 2006
View article titled, Notch Signaling Requires GATA-2 to Inhibit Myelopoiesis from Embryonic Stem Cells and Primary Hemopoietic Progenitors
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Journal Articles

Cutting Edge: Three-Dimensional Architecture of the Thymus Is Required to Maintain Delta-Like Expression Necessary for Inducing T Cell Development

Mahmood Mohtashami, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2006) 176 (2): 730–734.
https://doi.org/10.4049/jimmunol.176.2.730
Published: 15 January 2006
View article titled, Cutting Edge: Three-Dimensional Architecture of the Thymus Is Required to Maintain Delta-Like Expression Necessary for Inducing T Cell Development
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Journal Articles

Propensity of Adult Lymphoid Progenitors to Progress to DN2/3 Stage Thymocytes with Notch Receptor Ligation

Jiaxue Huang, Karla P. Garrett, Rosana Pelayo, Juan Carlos Zúñiga-Pflücker, Howard T. Petrie, Paul W. Kincade
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 4858–4865.
https://doi.org/10.4049/jimmunol.175.8.4858
Published: 15 October 2005
View article titled, Propensity of Adult Lymphoid Progenitors to Progress to DN2/3 Stage Thymocytes with Notch Receptor Ligation
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Journal Articles

Functional Requirements for Signaling through the Stimulatory and Inhibitory Mouse NKR-P1 (CD161) NK Cell Receptors

Belma Ljutic, James R. Carlyle, Dominik Filipp, Rinako Nakagawa, Michael Julius, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2005) 174 (8): 4789–4796.
https://doi.org/10.4049/jimmunol.174.8.4789
Published: 15 April 2005
View article titled, Functional Requirements for Signaling through the Stimulatory and Inhibitory Mouse NKR-P1 (CD161) NK Cell Receptors
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Journal Articles

Cyclic Adenosine 5′-Monophosphate Response Element Binding Protein Plays a Central Role in Mediating Proliferation and Differentiation Downstream of the Pre-TCR Complex in Developing Thymocytes

Gillian C. Grady, Susan M. Mason, Jillian Stephen, Juan Carlos Zúñiga-Pflücker, Alison M. Michie
Journal: The Journal of Immunology
J Immunol (2004) 173 (3): 1802–1810.
https://doi.org/10.4049/jimmunol.173.3.1802
Published: 01 August 2004
View article titled, Cyclic Adenosine 5′-Monophosphate Response Element Binding Protein Plays a Central Role in Mediating Proliferation and Differentiation Downstream of the Pre-TCR Complex in Developing Thymocytes
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Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation

Maria Ciofani, Thomas M. Schmitt, Amelia Ciofani, Alison M. Michie, Nicolas Çuburu, Anne Aublin, Janet L. Maryanski, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2004) 172 (9): 5230–5239.
https://doi.org/10.4049/jimmunol.172.9.5230
Published: 01 May 2004
View article titled, Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation
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Low Activation Threshold As a Mechanism for Ligand-Independent Signaling in Pre-T Cells

Mariëlle C. Haks, Stanley M. Belkowski, Maria Ciofani, Michele Rhodes, Juliette M. Lefebvre, Sebastién Trop, Patrice Hugo, Juan Carlos Zúñiga-Pflücker, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2003) 170 (6): 2853–2861.
https://doi.org/10.4049/jimmunol.170.6.2853
Published: 15 March 2003
View article titled, Low Activation Threshold As a Mechanism for Ligand-Independent Signaling in Pre-T Cells
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Journal Articles

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

Sanjeev Mariathasan, Arsen Zakarian, Denis Bouchard, Alison M. Michie, Juan Carlos Zúñiga-Pflücker, Pamela S. Ohashi
Journal: The Journal of Immunology
J Immunol (2001) 167 (9): 4966–4973.
https://doi.org/10.4049/jimmunol.167.9.4966
Published: 01 November 2001
View article titled, Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection
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Journal Articles

Competitive Displacement of pTα by TCR-α During TCR Assembly Prevents Surface Coexpression of Pre-TCR and αβ TCR

Sébastien Trop, Michele Rhodes, David L. Wiest, Patrice Hugo, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2000) 165 (10): 5566–5572.
https://doi.org/10.4049/jimmunol.165.10.5566
Published: 15 November 2000
View article titled, Competitive Displacement of pTα by TCR-α During TCR Assembly Prevents Surface Coexpression of Pre-TCR and αβ TCR
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Clonal Characterization of a Bipotent T Cell and NK Cell Progenitor in the Mouse Fetal Thymus

Alison M. Michie, James R. Carlyle, Thomas M. Schmitt, Belma Ljutic, Sarah K. Cho, Quyen Fong, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (2000) 164 (4): 1730–1733.
https://doi.org/10.4049/jimmunol.164.4.1730
Published: 15 February 2000
View article titled, Clonal Characterization of a Bipotent T Cell and NK Cell Progenitor in the Mouse Fetal Thymus
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Journal Articles

Mouse NKR-P1B, a Novel NK1.1 Antigen with Inhibitory Function

James R. Carlyle, Alberto Martin, Arun Mehra, Liliana Attisano, Florence W. Tsui, Juan Carlos Zúñiga-Pflücker
Journal: The Journal of Immunology
J Immunol (1999) 162 (10): 5917–5923.
https://doi.org/10.4049/jimmunol.162.10.5917
Published: 15 May 1999
View article titled, Mouse NKR-P1B, a Novel NK1.1 Antigen with Inhibitory Function
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