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Julie Zikherman
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Journal Articles

An Integrated Signaling Threshold Initiates IgG Response toward Virus-like Immunogens

Wei-Yun Wholey, Alexander R. Meyer, Sekou-Tidiane Yoda, James L. Mueller, Raisa Mathenge, Bryce Chackerian, Julie Zikherman, Wei Cheng
Journal: The Journal of Immunology
J Immunol (2024) 213 (8): 1061–1075.
https://doi.org/10.4049/jimmunol.2400101
Published: 30 August 2024
View article titled, An Integrated Signaling Threshold Initiates IgG Response toward Virus-like Immunogens
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Includes: Supplementary data
Journal Articles

CD22/Lyn-mediated suppression of trophoblast antigen-specific B cells underlies fetomaternal tolerance

Gabrielle Rizzuto, Jeremy Brooks, Susan Fisher, Julie Zikherman, Adrian Erlebacher
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 28.18.
https://doi.org/10.4049/jimmunol.206.Supp.28.18
Published: 01 May 2021
View article titled, CD22/Lyn-mediated suppression of trophoblast antigen-specific B cells underlies fetomaternal tolerance
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Journal Articles

Optimal Development of Mature B Cells Requires Recognition of Endogenous Antigens

Mark Noviski, Corey Tan, John Huizar, Vivasvan Vykunta, James L. Mueller, Julie Zikherman
Journal: The Journal of Immunology
J Immunol (2019) 203 (2): 418–428.
https://doi.org/10.4049/jimmunol.1900175
Published: 15 July 2019
View article titled, Optimal Development of Mature B Cells Requires Recognition of Endogenous Antigens
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Includes: Supplementary data
Journal Articles

Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery

Corey Tan, James L. Mueller, Mark Noviski, John Huizar, Denise Lau, Alexandra Dubinin, Ari Molofsky, Patrick C. Wilson, Julie Zikherman
Journal: The Journal of Immunology
J Immunol (2019) 202 (10): 2907–2923.
https://doi.org/10.4049/jimmunol.1801565
Published: 15 May 2019
View article titled, Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery
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Includes: Supplementary data
Journal Articles

IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level

Byron B. Au-Yeung, Geoffrey Alexander Smith, James L. Mueller, Cheryl S. Heyn, Rebecca Garrett Jaszczak, Arthur Weiss, Julie Zikherman
Journal: The Journal of Immunology
J Immunol (2017) 198 (6): 2445–2456.
https://doi.org/10.4049/jimmunol.1601453
Published: 15 March 2017
View article titled, IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level
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Includes: Supplementary data
Journal Articles

Unbiased Modifier Screen Reveals That Signal Strength Determines the Regulatory Role Murine TLR9 Plays in Autoantibody Production

Robyn E. Mills, Viola C. Lam, Allison Tan, Nicole Cresalia, Nir Oksenberg, Julie Zikherman, Mark Anderson, Arthur Weiss, Michelle L. Hermiston
Journal: The Journal of Immunology
J Immunol (2015) 194 (8): 3675–3686.
https://doi.org/10.4049/jimmunol.1500026
Published: 15 April 2015
View article titled, Unbiased Modifier Screen Reveals That Signal Strength Determines the Regulatory Role Murine TLR9 Plays in Autoantibody Production
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Includes: Supplementary data
Journal Articles

Cutting Edge: An In Vivo Reporter Reveals Active B Cell Receptor Signaling in the Germinal Center

James Mueller, Mehrdad Matloubian, Julie Zikherman
Journal: The Journal of Immunology
J Immunol (2015) 194 (7): 2993–2997.
https://doi.org/10.4049/jimmunol.1403086
Published: 01 April 2015
View article titled, Cutting Edge: An In Vivo Reporter Reveals Active B Cell Receptor Signaling in the Germinal Center
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Includes: Supplementary data
Journal Articles

The Structural Wedge Domain of the Receptor-like Tyrosine Phosphatase CD45 Enforces B Cell Tolerance by Regulating Substrate Specificity

Julie Zikherman, Ramya Parameswaran, Michelle Hermiston, Arthur Weiss
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2527–2535.
https://doi.org/10.4049/jimmunol.1202928
Published: 15 March 2013
View article titled, The Structural Wedge Domain of the Receptor-like Tyrosine Phosphatase CD45 Enforces B Cell Tolerance by Regulating Substrate Specificity
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Includes: Supplementary data
Journal Articles

Titration of CD45 expression regulates sequential tolerance checkpoints during B cell development (45.2)

Julie Zikherman, Kristin Doan, William Raschke, Arthur Weiss
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 45.2.
https://doi.org/10.4049/jimmunol.186.Supp.45.2
Published: 01 April 2011
View article titled, Titration of CD45 expression regulates sequential tolerance checkpoints during B cell development (45.2)
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Journal Articles

PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background

Julie Zikherman, Michelle Hermiston, David Steiner, Kiminori Hasegawa, Andrew Chan, Arthur Weiss
Journal: The Journal of Immunology
J Immunol (2009) 182 (7): 4093–4106.
https://doi.org/10.4049/jimmunol.0803317
Published: 01 April 2009
View article titled, <em>PTPN22</em> Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background
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Journal Articles

An allelic series of CD45 dosages uncouples basal and inducible TCR signaling during thymic development (84.13)

Julie Zikherman, Susan Watson, Craig Jenne, William C. Raschke, Christopher Goodnow, Arthur Weiss
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 84.13.
https://doi.org/10.4049/jimmunol.182.Supp.84.13
Published: 01 April 2009
View article titled, An allelic series of CD45 dosages uncouples basal and inducible TCR signaling during thymic development (84.13)
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Journal Articles

PTPN22 deficiency cooperates with the CD45 E613R wedge allele to break tolerance on a non-autoimmune background (49.18)

Julie Zikherman, Michelle Hermiston, David Steiner, Kiminori Hasegawa, Andrew Chan
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 49.18.
https://doi.org/10.4049/jimmunol.182.Supp.49.18
Published: 01 April 2009
View article titled, PTPN22 deficiency cooperates with the CD45 E613R wedge allele to break tolerance on a non-autoimmune background (49.18)
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