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Junichiro Mizuguchi
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Journal Articles

IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.

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Tomohiro Yoshimoto, Takayuki Yoshimoto, Koubun Yasuda, Junichiro Mizuguchi, Kenji Nakanishi
Journal: The Journal of Immunology
J Immunol (2010) 184 (6): 3298.
https://doi.org/10.4049/jimmunol.1090006
Published: 15 March 2010
View articletitled, IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
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Journal Articles

Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis in B cells (34.6)

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Junichiro Mizuguchi, Eiko Takada, Masae Furuhata
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 34.6.
https://doi.org/10.4049/jimmunol.182.Supp.34.6
Published: 01 April 2009
View articletitled, Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis in B cells (34.6)
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Journal Articles

Antiproliferative Activity of IL-27 on Melanoma

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Takayuki Yoshimoto, Noriko Morishima, Izuru Mizoguchi, Motomu Shimizu, Hiroshi Nagai, Shuntaro Oniki, Masahiro Oka, Chikako Nishigori, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2008) 180 (10): 6527–6535.
https://doi.org/10.4049/jimmunol.180.10.6527
Published: 15 May 2008
View articletitled, Antiproliferative Activity of IL-27 on Melanoma
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Journal Articles

STAT3 Is Indispensable to IL-27-Mediated Cell Proliferation but Not to IL-27-Induced Th1 Differentiation and Suppression of Proinflammatory Cytokine Production

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Toshiyuki Owaki, Masayuki Asakawa, Noriko Morishima, Izuru Mizoguchi, Fumio Fukai, Kiyoshi Takeda, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 2903–2911.
https://doi.org/10.4049/jimmunol.180.5.2903
Published: 01 March 2008
View articletitled, STAT3 Is Indispensable to IL-27-Mediated Cell Proliferation but Not to IL-27-Induced Th1 Differentiation and Suppression of Proinflammatory Cytokine Production
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Journal Articles

IL-27 Suppresses Th2 Cell Development and Th2 Cytokines Production from Polarized Th2 Cells: A Novel Therapeutic Way for Th2-Mediated Allergic Inflammation

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Tomohiro Yoshimoto, Takayuki Yoshimoto, Koubun Yasuda, Junichiro Mizuguchi, Kenji Nakanishi
Journal: The Journal of Immunology
J Immunol (2007) 179 (7): 4415–4423.
https://doi.org/10.4049/jimmunol.179.7.4415
Published: 01 October 2007
View articletitled, IL-27 Suppresses Th2 Cell Development and Th2 Cytokines Production from Polarized Th2 Cells: A Novel Therapeutic Way for Th2-Mediated Allergic Inflammation
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Journal Articles

Anti-proliferative effect of interleukin-27 on melanoma cells (48.23)

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Takayuki Yoshimoto, Noriko Morishima, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S79.
https://doi.org/10.4049/jimmunol.178.Supp.48.23
Published: 01 April 2007
View articletitled, Anti-proliferative effect of interleukin-27 on melanoma cells (48.23)
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Journal Articles

IL-27 Induces Th1 Differentiation via p38 MAPK/T-bet- and Intercellular Adhesion Molecule-1/LFA-1/ERK1/2-Dependent Pathways

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Toshiyuki Owaki, Masayuki Asakawa, Fumio Fukai, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2006) 177 (11): 7579–7587.
https://doi.org/10.4049/jimmunol.177.11.7579
Published: 01 December 2006
View articletitled, IL-27 Induces Th1 Differentiation via p38 MAPK/T-bet- and Intercellular Adhesion Molecule-1/LFA-1/ERK1/2-Dependent Pathways
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Journal Articles

Antigen Chemically Coupled to the Surface of Liposomes Are Cross-Presented to CD8+ T Cells and Induce Potent Antitumor Immunity

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Maiko Taneichi, Hideaki Ishida, Kiichi Kajino, Kazumasa Ogasawara, Yuriko Tanaka, Michiyuki Kasai, Masahito Mori, Mitsuhiro Nishida, Hiroyuki Yamamura, Junichiro Mizuguchi, Tetsuya Uchida
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2324–2330.
https://doi.org/10.4049/jimmunol.177.4.2324
Published: 15 August 2006
View articletitled, Antigen Chemically Coupled to the Surface of Liposomes Are Cross-Presented to CD8+ T Cells and Induce Potent Antitumor Immunity
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Journal Articles

Antiangiogenic and Antitumor Activities of IL-27

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Motomu Shimizu, Mariko Shimamura, Toshiyuki Owaki, Masayuki Asakawa, Koji Fujita, Motoshige Kudo, Yoichiro Iwakura, Yasutaka Takeda, Andrew D. Luster, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2006) 176 (12): 7317–7324.
https://doi.org/10.4049/jimmunol.176.12.7317
Published: 15 June 2006
View articletitled, Antiangiogenic and Antitumor Activities of IL-27
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Journal Articles

IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3

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Toshiyuki Owaki, Masayuki Asakawa, Sadahiro Kamiya, Kiyoshi Takeda, Fumio Fukai, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2006) 176 (5): 2773–2780.
https://doi.org/10.4049/jimmunol.176.5.2773
Published: 01 March 2006
View articletitled, IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3
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Journal Articles

A Role for IL-27 in Early Regulation of Th1 Differentiation

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Toshiyuki Owaki, Masayuki Asakawa, Noriko Morishima, Kikumi Hata, Fumio Fukai, Masanori Matsui, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2005) 175 (4): 2191–2200.
https://doi.org/10.4049/jimmunol.175.4.2191
Published: 15 August 2005
View articletitled, A Role for IL-27 in Early Regulation of Th1 Differentiation
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Journal Articles

Augmentation of Effector CD8+ T Cell Generation with Enhanced Granzyme B Expression by IL-27

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Noriko Morishima, Toshiyuki Owaki, Masayuki Asakawa, Sadahiro Kamiya, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2005) 175 (3): 1686–1693.
https://doi.org/10.4049/jimmunol.175.3.1686
Published: 01 August 2005
View articletitled, Augmentation of Effector CD8+ T Cell Generation with Enhanced Granzyme B Expression by IL-27
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Journal Articles

An Indispensable Role for STAT1 in IL-27-Induced T-bet Expression but Not Proliferation of Naive CD4+ T Cells

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Sadahiro Kamiya, Toshiyuki Owaki, Noriko Morishima, Fumio Fukai, Junichiro Mizuguchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2004) 173 (6): 3871–3877.
https://doi.org/10.4049/jimmunol.173.6.3871
Published: 15 September 2004
View articletitled, An Indispensable Role for STAT1 in IL-27-Induced T-bet Expression but Not Proliferation of Naive CD4+ T Cells
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Journal Articles

Induction of IgG2a Class Switching in B Cells by IL-27

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Takayuki Yoshimoto, Keiko Okada, Noriko Morishima, Sadahiro Kamiya, Toshiyuki Owaki, Masayuki Asakawa, Yoichiro Iwakura, Fumio Fukai, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2004) 173 (4): 2479–2485.
https://doi.org/10.4049/jimmunol.173.4.2479
Published: 15 August 2004
View articletitled, Induction of IgG2a Class Switching in B Cells by IL-27
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Journal Articles

CD40 Ligand Rescues Inhibitor of Differentiation 3-Mediated G1 Arrest Induced by Anti-IgM in WEHI-231 B Lymphoma Cells

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Kikumi Hata, Takayuki Yoshimoto, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2004) 173 (4): 2453–2461.
https://doi.org/10.4049/jimmunol.173.4.2453
Published: 15 August 2004
View articletitled, CD40 Ligand Rescues Inhibitor of Differentiation 3-Mediated G1 Arrest Induced by Anti-IgM in WEHI-231 B Lymphoma Cells
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Journal Articles

Positive Modulation of IL-12 Signaling by Sphingosine Kinase 2 Associating with the IL-12 Receptor β1 Cytoplasmic Region

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Takayuki Yoshimoto, Masae Furuhata, Sadahiro Kamiya, Masayuki Hisada, Hiroko Miyaji, Yasushi Magami, Koh Yamamoto, Hiromi Fujiwara, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2003) 171 (3): 1352–1359.
https://doi.org/10.4049/jimmunol.171.3.1352
Published: 01 August 2003
View articletitled, Positive Modulation of IL-12 Signaling by Sphingosine Kinase 2 Associating with the IL-12 Receptor β1 Cytoplasmic Region
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Journal Articles

A Critical Role of Fc Receptor-Mediated Antibody-Dependent Phagocytosis in the Host Resistance to Blood-Stage Plasmodium berghei XAT Infection

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Toshihiko Yoneto, Seiji Waki, Toshihiro Takai, Yoh-ichi Tagawa, Yoichiro Iwakura, Junichiro Mizuguchi, Hideo Nariuchi, Takayuki Yoshimoto
Journal: The Journal of Immunology
J Immunol (2001) 166 (10): 6236–6241.
https://doi.org/10.4049/jimmunol.166.10.6236
Published: 15 May 2001
View articletitled, A Critical Role of Fc Receptor-Mediated Antibody-Dependent Phagocytosis in the Host Resistance to Blood-Stage Plasmodium berghei XAT Infection
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Journal Articles

Prevention of Anti-IgM-Induced Apoptosis Accompanying G1 Arrest in B Lymphoma Cells Overexpressing Dominant-Negative Mutant Form of c-Jun N-Terminal Kinase 1

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Eiko Takada, Hiroko Toyota, Jun Suzuki, Junichiro Mizuguchi
Journal: The Journal of Immunology
J Immunol (2001) 166 (3): 1641–1649.
https://doi.org/10.4049/jimmunol.166.3.1641
Published: 01 February 2001
View articletitled, Prevention of Anti-IgM-Induced Apoptosis Accompanying G1 Arrest in B Lymphoma Cells Overexpressing Dominant-Negative Mutant Form of c-Jun N-Terminal Kinase 1
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