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K E Hellström
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Journal Articles

B7-negative versus B7-positive P815 tumor: differential requirements for priming of an antitumor immune response in lymph nodes.

G Yang, M T Mizuno, K E Hellström, L Chen
Journal: The Journal of Immunology
J Immunol (1997) 158 (2): 851–858.
https://doi.org/10.4049/jimmunol.158.2.851
Published: 15 January 1997
View article titled, B7-negative versus B7-positive P815 tumor: differential requirements for priming of an antitumor immune response in lymph nodes.
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Journal Articles

Protective immunity induced by B7/CD28-costimulated gamma delta T cells to the EL-4 lymphoma in allogenic athymic mice.

Y Li, S A Newby, J V Johnston, K E Hellström, L Chen
Journal: The Journal of Immunology
J Immunol (1995) 155 (12): 5705–5710.
https://doi.org/10.4049/jimmunol.155.12.5705
Published: 15 December 1995
View article titled, Protective immunity induced by B7/CD28-costimulated gamma delta T cells to the EL-4 lymphoma in allogenic athymic mice.
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Journal Articles

In vitro priming of tumor-reactive cytolytic T lymphocytes by combining IL-10 with B7-CD28 costimulation.

G Yang, K E Hellström, M T Mizuno, L Chen
Journal: The Journal of Immunology
J Immunol (1995) 155 (8): 3897–3903.
https://doi.org/10.4049/jimmunol.155.8.3897
Published: 15 October 1995
View article titled, In vitro priming of tumor-reactive cytolytic T lymphocytes by combining IL-10 with B7-CD28 costimulation.
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Journal Articles

Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesis.

D E Yelton, M J Rosok, G Cruz, W L Cosand, J Bajorath, I Hellström, K E Hellström, W D Huse, S M Glaser
Journal: The Journal of Immunology
J Immunol (1995) 155 (4): 1994–2004.
https://doi.org/10.4049/jimmunol.155.4.1994
Published: 15 August 1995
View article titled, Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesis.
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Journal Articles

Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 costimulatory molecules.

G Yang, K E Hellström, I Hellström, L Chen
Journal: The Journal of Immunology
J Immunol (1995) 154 (6): 2794–2800.
https://doi.org/10.4049/jimmunol.154.6.2794
Published: 15 March 1995
View article titled, Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 costimulatory molecules.
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Journal Articles

Costimulation of tumor-reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma.

Y Li, P McGowan, I Hellström, K E Hellström, L Chen
Journal: The Journal of Immunology
J Immunol (1994) 153 (1): 421–428.
https://doi.org/10.4049/jimmunol.153.1.421
Published: 01 July 1994
View article titled, Costimulation of tumor-reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma.
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Journal Articles

In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.

C B Siegall, D Chace, B Mixan, U Garrigues, H Wan, L Paul, E Wolff, I Hellström, K E Hellström
Journal: The Journal of Immunology
J Immunol (1994) 152 (5): 2377–2384.
https://doi.org/10.4049/jimmunol.152.5.2377
Published: 01 March 1994
View article titled, In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.
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Journal Articles

Application of a filamentous phage pVIII fusion protein system suitable for efficient production, screening, and mutagenesis of F(ab) antibody fragments.

W D Huse, T J Stinchcombe, S M Glaser, L Starr, M MacLean, K E Hellström, I Hellström, D E Yelton
Journal: The Journal of Immunology
J Immunol (1992) 149 (12): 3914–3920.
https://doi.org/10.4049/jimmunol.149.12.3914
Published: 15 December 1992
View article titled, Application of a filamentous phage pVIII fusion protein system suitable for efficient production, screening, and mutagenesis of F(ab) antibody fragments.
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Journal Articles

Induction of cytotoxic T lymphocytes specific for a syngeneic tumor expressing the E6 oncoprotein of human papillomavirus type 16.

L Chen, M T Mizuno, M C Singhal, S L Hu, D A Galloway, I Hellström, K E Hellström
Journal: The Journal of Immunology
J Immunol (1992) 148 (8): 2617–2621.
https://doi.org/10.4049/jimmunol.148.8.2617
Published: 15 April 1992
View article titled, Induction of cytotoxic T lymphocytes specific for a syngeneic tumor expressing the E6 oncoprotein of human papillomavirus type 16.
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Journal Articles

CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen.

M Kahn, H Sugawara, P McGowan, K Okuno, S Nagoya, K E Hellström, I Hellström, P Greenberg
Journal: The Journal of Immunology
J Immunol (1991) 146 (9): 3235–3241.
https://doi.org/10.4049/jimmunol.146.9.3235
Published: 01 May 1991
View article titled, CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen.
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Journal Articles

Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response.

N G Chakraborty, D R Twardzik, M Sivanandham, M T Ergin, K E Hellstrom, B Mukherji
Journal: The Journal of Immunology
J Immunol (1990) 145 (7): 2359–2364.
https://doi.org/10.4049/jimmunol.145.7.2359
Published: 01 October 1990
View article titled, Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response.
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Journal Articles

Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity.

A Y Liu, R R Robinson, E D Murray, Jr, J A Ledbetter, I Hellström, K E Hellström
Journal: The Journal of Immunology
J Immunol (1987) 139 (10): 3521–3526.
https://doi.org/10.4049/jimmunol.139.10.3521
Published: 15 November 1987
View article titled, Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity.
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Journal Articles

Induction of calcium flux and enhancement of cytolytic activity in natural killer cells by cross-linking of the sheep erythrocyte binding protein (CD2) and the Fc-receptor (CD16).

C Anasetti, P J Martin, C H June, K E Hellstrom, J A Ledbetter, P S Rabinovitch, Y Morishita, I Hellstrom, J A Hansen
Journal: The Journal of Immunology
J Immunol (1987) 139 (6): 1772–1779.
https://doi.org/10.4049/jimmunol.139.6.1772
Published: 15 September 1987
View article titled, Induction of calcium flux and enhancement of cytolytic activity in natural killer cells by cross-linking of the sheep erythrocyte binding protein (CD2) and the Fc-receptor (CD16).
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Journal Articles

Immunotherapy of murine sarcomas with auto-anti-idiotypic monoclonal antibodies which bind to tumor-specific T cells.

K A Nelson, E George, C Swenson, J W Forstrom, K E Hellström
Journal: The Journal of Immunology
J Immunol (1987) 139 (6): 2110–2117.
https://doi.org/10.4049/jimmunol.139.6.2110
Published: 15 September 1987
View article titled, Immunotherapy of murine sarcomas with auto-anti-idiotypic monoclonal antibodies which bind to tumor-specific T cells.
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Journal Articles

Studies of a high molecular weight human melanoma-associated antigen.

I Hellström, H J Garrigues, L Cabasco, G H Mosely, J P Brown, K E Hellström
Journal: The Journal of Immunology
J Immunol (1983) 130 (3): 1467–1472.
https://doi.org/10.4049/jimmunol.130.3.1467
Published: 01 March 1983
View article titled, Studies of a high molecular weight human melanoma-associated antigen.
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Journal Articles

Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies.

J P Brown, K Nishiyama, I Hellström, K E Hellström
Journal: The Journal of Immunology
J Immunol (1981) 127 (2): 539–546.
https://doi.org/10.4049/jimmunol.127.2.539
Published: 01 August 1981
View article titled, Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies.
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Journal Articles

Monoclonal antibodies to two determinants of melanoma-antigen p97 act synergistically in complement-dependent cytotoxicity.

I Hellström, J P Brown, K E Hellström
Journal: The Journal of Immunology
J Immunol (1981) 127 (1): 157–160.
https://doi.org/10.4049/jimmunol.127.1.157
Published: 01 July 1981
View article titled, Monoclonal antibodies to two determinants of melanoma-antigen p97 act synergistically in complement-dependent cytotoxicity.
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Journal Articles

Clonal variation in expression of a human melanoma antigen defined by a monoclonal antibody.

M Y Yeh, I Hellström, K E Hellström
Journal: The Journal of Immunology
J Immunol (1981) 126 (4): 1312–1317.
https://doi.org/10.4049/jimmunol.126.4.1312
Published: 01 April 1981
View article titled, Clonal variation in expression of a human melanoma antigen defined by a monoclonal antibody.
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Journal Articles

Antibodies to murine leukemia virus gp70 and p15(E) in sera of BALB/c mice immunized with syngeneic chemically induced sarcomas.

J M Klitzman, J P Brown, K E Hellström, I Hellström
Journal: The Journal of Immunology
J Immunol (1980) 124 (6): 2552–2556.
https://doi.org/10.4049/jimmunol.124.6.2552
Published: 01 June 1980
View article titled, Antibodies to murine leukemia virus gp70 and p15(E) in sera of BALB/c mice immunized with syngeneic chemically induced sarcomas.
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Journal Articles

Selective Localization of Radiolabeled Immune Lymphocytes into Syngeneic Tumors

J. J. Mulé, F. R. Jones, I. Hellström, K. E. Hellström
Journal: The Journal of Immunology
J Immunol (1979) 123 (2): 600–606.
https://doi.org/10.4049/jimmunol.123.2.600
Published: 01 August 1979
View article titled, Selective Localization of Radiolabeled Immune Lymphocytes into Syngeneic Tumors
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