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Mast cell-intrinsic TGF-b signaling modulates mast cell effector function and allergic responses

Tamara Haque, Lashawna Leak, Emily Youngblood, Karen Laky, Pamela Frischmeyer-Guerrerio

J Immunol (2024) 212 (1_Supplement): 1058_4788.

https://doi.org/10.4049/jimmunol.212.supp.1058.4788

Published: 01 May 2024

View articletitled, Mast cell-intrinsic TGF-b signaling modulates mast cell effector function and allergic responses

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Journal Articles

Cell-Intrinsic Effects of TGF-b Signaling in Mast Cell Effector Function that Modulate Allergic Inflammation

Tamara Haque, Leshawna Leak, Karen Laky, Pamela Guererrio

J Immunol (2023) 210 (1_Supplement): 151.05.

https://doi.org/10.4049/jimmunol.210.Supp.151.05

Published: 01 May 2023

View articletitled, Cell-Intrinsic Effects of TGF-b Signaling in Mast Cell Effector Function that Modulate Allergic Inflammation

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Journal Articles

Dysregulated TGF-β Signaling Leads to Cell-Intrinsic Changes in T cell Development that Promote Allergic Inflammation

Tamara Haque, Kate Weissler, Zoe Schmiechen, Lashawna Leak, Karen Laky, Pamela A Frischmeyer-Guerrerio

J Immunol (2021) 206 (1_Supplement): 94.07.

https://doi.org/10.4049/jimmunol.206.Supp.94.07

Published: 01 May 2021

View articletitled, Dysregulated TGF-β Signaling Leads to Cell-Intrinsic Changes in T cell Development that Promote Allergic Inflammation

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Journal Articles

Mutation of Tgfbr1 leads to non-hematopoietic defects that drive early onset eosinophilic inflammation in the esophagus

Karen Laky, Jessica L Kinard, Anthony Guerrerio, Min Jenny Li, Pamela Guerrerio

J Immunol (2019) 202 (1_Supplement): 67.15.

https://doi.org/10.4049/jimmunol.202.Supp.67.15

Published: 01 May 2019

View articletitled, Mutation of Tgfbr1 leads to non-hematopoietic defects that drive early onset eosinophilic inflammation in the esophagus

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Journal Articles

The effects of altered TGFβ signaling on human T follicular helper cell development and function

Zoe C Schmiechen, Katherine Weissler, Karen Laky, Pamela Guerrerio

J Immunol (2019) 202 (1_Supplement): 182.52.

https://doi.org/10.4049/jimmunol.202.Supp.182.52

Published: 01 May 2019

View articletitled, The effects of altered TGFβ signaling on human T follicular helper cell development and function

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Journal Articles

Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection

Caroline M. Percopo, Michelle Ma, Todd A. Brenner, Julia O. Krumholz, Timothy J. Break, Karen Laky, Helene F. Rosenberg

J Immunol (2019) 202 (3): 871–882.

https://doi.org/10.4049/jimmunol.1800927

Published: 01 February 2019

View articletitled, Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection

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Includes: Supplementary data

Journal Articles

Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells

Kaveh Abdi, Karen Laky, Kartika Padhan, Constantinos Petrovas, Jeff Skinner, Juraj Kabat, David W. Dorward, Joseph Brzostowski, Eric O. Long, Giorgio Trinchieri, Rajat Varma

J Immunol (2018) 201 (10): 2879–2884.

https://doi.org/10.4049/jimmunol.1800721

Published: 15 November 2018

View articletitled, Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells

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Includes: Multimedia, Supplementary data

Journal Articles

Altered TGFβ signaling in non-hematopoietic cells leads to eosinophilic esophagitis.

Karen Laky, Jessica Kinard, Anthony Guerrerio, Pamela Frischmeyer-Guerrerio

J Immunol (2018) 200 (1_Supplement): 104.11.

https://doi.org/10.4049/jimmunol.200.Supp.104.11

Published: 01 May 2018

View articletitled, Altered TGFβ signaling in non-hematopoietic cells leads to eosinophilic esophagitis.

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Journal Articles

TGFBR1M318R^+/−: A monogenic presentation of eosinophilic esophagitis.

Karen Laky, Jessica L. Kinard, Anthony Guerrerio, Pamela Frischmeyer-Guerrerio

J Immunol (2017) 198 (1_Supplement): 149.24.

https://doi.org/10.4049/jimmunol.198.Supp.149.24

Published: 01 May 2017

View articletitled, TGFBR1M318R+/−: A monogenic presentation of eosinophilic esophagitis.

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Journal Articles

Phenotypic Characterization of ILC2s in an EoE Mouse Model

Jessica L. Kinard, Karen Laky, Anthony Guerrerio, Pamela Frischmeyer-Guerrerio

J Immunol (2017) 198 (1_Supplement): 59.11.

https://doi.org/10.4049/jimmunol.198.Supp.59.11

Published: 01 May 2017

View articletitled, Phenotypic Characterization of ILC2s in an EoE Mouse Model

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Journal Articles

Reduced TGF‑βR signaling results in increased T cell activation without autoinflammatory disease

Katherine Ann Weissler, Jessica Kinard, Karen Laky, Pamela Guerrerio

J Immunol (2017) 198 (1_Supplement): 144.4.

https://doi.org/10.4049/jimmunol.198.Supp.144.4

Published: 01 May 2017

View articletitled, Reduced TGF‑βR signaling results in increased T cell activation without autoinflammatory disease

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Journal Articles

TGFBR1M318R^+/− Knock-In mice recapitulate the immune phenotypes of Loeys-Dietz syndrome.

Karen Laky, Anthony Guerrerio, Katherine A Weissler, Pamela Frischmeyer-Guerrerio

J Immunol (2016) 196 (1_Supplement): 193.13.

https://doi.org/10.4049/jimmunol.196.Supp.193.13

Published: 01 May 2016

View articletitled, TGFBR1M318R+/− Knock-In mice recapitulate the immune phenotypes of Loeys-Dietz syndrome.

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Journal Articles

Toxoplasma gondii infection triggers a long-term defect in the generation and function of naive CD4⁺ T lymphocytes

Dragana Jankovic, David G. Kugler, Francis A. Flomerfelt, Diego L. Costa, Karen Laky, Olena Kamenyeva, Paul R. Mittelstadt, Ronald E. Gress, Jonathan D. Ashwell, Alan Sher

J Immunol (2016) 196 (1_Supplement): 205.1.

https://doi.org/10.4049/jimmunol.196.Supp.205.1

Published: 01 May 2016

View articletitled, Toxoplasma gondii infection triggers a long-term defect in the generation and function of naive CD4+ T lymphocytes

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Journal Articles

Notch signaling regulates antigen sensitivity of naive CD4⁺ T cells by tuning co-stimulation (LYM7P.613)

Karen Laky, Sharron Evans, B Fowlkes

J Immunol (2015) 194 (1_Supplement): 200.5.

https://doi.org/10.4049/jimmunol.194.Supp.200.5

Published: 01 May 2015

View articletitled, Notch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation (LYM7P.613)

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Journal Articles

Unexpected Role for the B Cell-Specific Src Family Kinase B Lymphoid Kinase in the Development of IL-17–Producing γδ T Cells

Renee M. Laird, Karen Laky, Sandra M. Hayes

J Immunol (2010) 185 (11): 6518–6527.

https://doi.org/10.4049/jimmunol.1002766

Published: 01 December 2010

View articletitled, Unexpected Role for the B Cell-Specific Src Family Kinase B Lymphoid Kinase in the Development of IL-17–Producing γδ T Cells

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Includes: Supplementary data

Journal Articles

Coordinate Regulation of TCR signaling, Notch, and Gata3 in T Cell Development (138.27)

Amanda Agyemang, Xianyu Zhang, Karen Laky, B.J. Fowlkes

J Immunol (2009) 182 (1_Supplement): 138.27.

https://doi.org/10.4049/jimmunol.182.Supp.138.27

Published: 01 April 2009

View articletitled, Coordinate Regulation of TCR signaling, Notch, and Gata3 in T Cell Development (138.27)

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Journal Articles

Distinct Requirements for IL-7 in Development of TCRγδ Cells During Fetal and Adult Life

Karen Laky, Julia M. Lewis, Robert E. Tigelaar, Lynn Puddington

J Immunol (2003) 170 (8): 4087–4094.

https://doi.org/10.4049/jimmunol.170.8.4087

Published: 15 April 2003

View articletitled, Distinct Requirements for IL-7 in Development of TCRγδ Cells During Fetal and Adult Life

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Mast cell-intrinsic TGF-b signaling modulates mast cell effector function and allergic responses

Cell-Intrinsic Effects of TGF-b Signaling in Mast Cell Effector Function that Modulate Allergic Inflammation

Dysregulated TGF-β Signaling Leads to Cell-Intrinsic Changes in T cell Development that Promote Allergic Inflammation

Mutation of Tgfbr1 leads to non-hematopoietic defects that drive early onset eosinophilic inflammation in the esophagus

The effects of altered TGFβ signaling on human T follicular helper cell development and function

Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection

Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells

Altered TGFβ signaling in non-hematopoietic cells leads to eosinophilic esophagitis.

TGFBR1M318R^+/−: A monogenic presentation of eosinophilic esophagitis.

Phenotypic Characterization of ILC2s in an EoE Mouse Model

Reduced TGF‑βR signaling results in increased T cell activation without autoinflammatory disease

TGFBR1M318R^+/− Knock-In mice recapitulate the immune phenotypes of Loeys-Dietz syndrome.

Toxoplasma gondii infection triggers a long-term defect in the generation and function of naive CD4⁺ T lymphocytes

Notch signaling regulates antigen sensitivity of naive CD4⁺ T cells by tuning co-stimulation (LYM7P.613)

Unexpected Role for the B Cell-Specific Src Family Kinase B Lymphoid Kinase in the Development of IL-17–Producing γδ T Cells

Coordinate Regulation of TCR signaling, Notch, and Gata3 in T Cell Development (138.27)

Distinct Requirements for IL-7 in Development of TCRγδ Cells During Fetal and Adult Life

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