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Kenji Funami
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Journal Articles

Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type–Specific Manner

Megumi Tatematsu, Ryuji Yoshida, Yuka Morioka, Noriko Ishii, Kenji Funami, Ayako Watanabe, Kazuko Saeki, Tsukasa Seya, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2016) 196 (9): 3865–3876.
https://doi.org/10.4049/jimmunol.1501734
Published: 01 May 2016
View article titled, Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type–Specific Manner
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Includes: Supplementary data
Journal Articles

LRRC59 Regulates Trafficking of Nucleic Acid–Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1

Megumi Tatematsu, Kenji Funami, Noriko Ishii, Tsukasa Seya, Chikashi Obuse, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2015) 195 (10): 4933–4942.
https://doi.org/10.4049/jimmunol.1501305
Published: 15 November 2015
View article titled, LRRC59 Regulates Trafficking of Nucleic Acid–Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1
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Includes: Supplementary data
Journal Articles

Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2

Kenji Funami, Misako Matsumoto, Yoshiaki Enokizono, Noriko Ishii, Megumi Tatematsu, Hiroyuki Oshiumi, Fuyuhiko Inagaki, Tsukasa Seya
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4456–4465.
https://doi.org/10.4049/jimmunol.1402628
Published: 01 November 2015
View article titled, Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2
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Includes: Supplementary data
Journal Articles

Endosomal Localization of TLR8 Confers Distinctive Proteolytic Processing on Human Myeloid Cells

Noriko Ishii, Kenji Funami, Megumi Tatematsu, Tsukasa Seya, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2014) 193 (10): 5118–5128.
https://doi.org/10.4049/jimmunol.1401375
Published: 15 November 2014
View article titled, Endosomal Localization of TLR8 Confers Distinctive Proteolytic Processing on Human Myeloid Cells
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Includes: Supplementary data
Journal Articles

Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor

Florent Toscano, Yann Estornes, François Virard, Alejandra Garcia-Cattaneo, Audrey Pierrot, Béatrice Vanbervliet, Marc Bonnin, Michael J. Ciancanelli, Shen-Ying Zhang, Kenji Funami, Tsukasa Seya, Misako Matsumoto, Jean-Jacques Pin, Jean-Laurent Casanova, Toufic Renno, Serge Lebecque
Journal: The Journal of Immunology
J Immunol (2013) 190 (2): 764–773.
https://doi.org/10.4049/jimmunol.1202173
Published: 15 January 2013
View article titled, Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor
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Includes: Supplementary data
Journal Articles

The Clathrin-Mediated Endocytic Pathway Participates in dsRNA-Induced IFN-β Production

Kiyoharu Itoh, Ayako Watanabe, Kenji Funami, Tsukasa Seya, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2008) 181 (8): 5522–5529.
https://doi.org/10.4049/jimmunol.181.8.5522
Published: 15 October 2008
View article titled, The Clathrin-Mediated Endocytic Pathway Participates in dsRNA-Induced IFN-β Production
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Journal Articles

Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA

Kenji Funami, Miwa Sasai, Yusuke Ohba, Hiroyuki Oshiumi, Tsukasa Seya, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 6867–6872.
https://doi.org/10.4049/jimmunol.179.10.6867
Published: 15 November 2007
View article titled, Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA
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Journal Articles

NAK-Associated Protein 1 Participates in Both the TLR3 and the Cytoplasmic Pathways in Type I IFN Induction

Miwa Sasai, Masashi Shingai, Kenji Funami, Mitsutoshi Yoneyama, Takashi Fujita, Misako Matsumoto, Tsukasa Seya
Journal: The Journal of Immunology
J Immunol (2006) 177 (12): 8676–8683.
https://doi.org/10.4049/jimmunol.177.12.8676
Published: 15 December 2006
View article titled, NAK-Associated Protein 1 Participates in Both the TLR3 and the Cytoplasmic Pathways in Type I IFN Induction
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Journal Articles

Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation

Junji Uehori, Koichi Fukase, Takashi Akazawa, Satoshi Uematsu, Shizuo Akira, Kenji Funami, Masashi Shingai, Misako Matsumoto, Ichiro Azuma, Kumao Toyoshima, Shoichi Kusumoto, Tsukasa Seya
Journal: The Journal of Immunology
J Immunol (2005) 174 (11): 7096–7103.
https://doi.org/10.4049/jimmunol.174.11.7096
Published: 01 June 2005
View article titled, Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation
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Journal Articles

Surface-Expressed TLR6 Participates in the Recognition of Diacylated Lipopeptide and Peptidoglycan in Human Cells

Yoshiya Nakao, Kenji Funami, Satomi Kikkawa, Mitsue Taniguchi, Miyuki Nishiguchi, Yasuhiro Fukumori, Tsukasa Seya, Misako Matsumoto
Journal: The Journal of Immunology
J Immunol (2005) 174 (3): 1566–1573.
https://doi.org/10.4049/jimmunol.174.3.1566
Published: 01 February 2005
View article titled, Surface-Expressed TLR6 Participates in the Recognition of Diacylated Lipopeptide and Peptidoglycan in Human Cells
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Journal Articles

Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

Misako Matsumoto, Kenji Funami, Masako Tanabe, Hiroyuki Oshiumi, Masashi Shingai, Yoshiyuki Seto, Akitsugu Yamamoto, Tsukasa Seya
Journal: The Journal of Immunology
J Immunol (2003) 171 (9): 4934.
https://doi.org/10.4049/jimmunol.171.9.4934-b
Published: 01 November 2003
View article titled, Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
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Journal Articles

Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

Misako Matsumoto, Kenji Funami, Masako Tanabe, Hiroyuki Oshiumi, Masashi Shingai, Yoshiyuki Seto, Akitsugu Yamamoto, Tsukasa Seya
Journal: The Journal of Immunology
J Immunol (2003) 171 (6): 3154–3162.
https://doi.org/10.4049/jimmunol.171.6.3154
Published: 15 September 2003
View article titled, Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
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