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6-Methyladenine may enhance immunostimulatory activity of bacterial genomic DNA

Yumiko Tsukamoto, Toshiki Tamura, Yumi Maeda, Kensuke Miyake, Manabu Ato

J Immunol (2020) 204 (1_Supplement): 226.17.

DOI: https://doi.org/10.4049/jimmunol.204.Supp.226.17

Published: 01 May 2020

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Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA

Jelka Pohar, Chikako Yamamoto, Ryutaro Fukui, Miša-Mojca Cajnko, Kensuke Miyake, Roman Jerala, Mojca Benčina

J Immunol (2017) 198 (5): 2093–2104.

DOI: https://doi.org/10.4049/jimmunol.1600757

Published: 01 March 2017

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Includes: Supplementary data

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Type I IFN Contributes to the Phenotype of Unc93b1^D34A/D34A Mice by Regulating TLR7 Expression in B Cells and Dendritic Cells

Ryutaro Fukui, Atsuo Kanno, Kensuke Miyake

J Immunol (2016) 196 (1): 416–427.

DOI: https://doi.org/10.4049/jimmunol.1500071

Published: 01 January 2016

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Species-Specific Minimal Sequence Motif for Oligodeoxyribonucleotides Activating Mouse TLR9

Jelka Pohar, Duško Lainšček, Ryutaro Fukui, Chikako Yamamoto, Kensuke Miyake, Roman Jerala, Mojca Benčina

J Immunol (2015) 195 (9): 4396–4405.

DOI: https://doi.org/10.4049/jimmunol.1500600

Published: 01 November 2015

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Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses

Toshifumi Kimura, Shota Endo, Masanori Inui, Shin-Ichiroh Saitoh, Kensuke Miyake, Toshiyuki Takai

J Immunol (2015) 194 (11): 5426–5436.

DOI: https://doi.org/10.4049/jimmunol.1402006

Published: 01 June 2015

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Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses

Kerstin Nündel, Nathaniel M. Green, Arthur L. Shaffer, Krishna L. Moody, Patricia Busto, Dan Eilat, Kensuke Miyake, Michael A. Oropallo, Michael P. Cancro, Ann Marshak-Rothstein

J Immunol (2015) 194 (6): 2504–2512.

DOI: https://doi.org/10.4049/jimmunol.1402425

Published: 15 March 2015

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Roles of the Cleaved N-Terminal TLR3 Fragment and Cell Surface TLR3 in Double-Stranded RNA Sensing

Yusuke Murakami, Ryutaro Fukui, Yuji Motoi, Atsuo Kanno, Takuma Shibata, Natsuko Tanimura, Shin-ichiroh Saitoh, Kensuke Miyake

J Immunol (2014) 193 (10): 5208–5217.

DOI: https://doi.org/10.4049/jimmunol.1400386

Published: 15 November 2014

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Serum Amyloid A3 Binds MD-2 To Activate p38 and NF-κB Pathways in a MyD88-Dependent Manner

Atsuko Deguchi, Takeshi Tomita, Tsutomu Omori, Akiko Komatsu, Umeharu Ohto, Satoshi Takahashi, Natsuko Tanimura, Sachiko Akashi-Takamura, Kensuke Miyake, Yoshiro Maru

J Immunol (2013) 191 (4): 1856–1864.

DOI: https://doi.org/10.4049/jimmunol.1201996

Published: 15 August 2013

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Differential requirements of CD14 and Lipopolysaccharide Binding Protein in Monophosphoryl lipid A-mediated TLR4 activation (P1209)

Natsuko Tanimura, Kensuke Miyake

J Immunol (2013) 190 (1_Supplement): 138.3.

DOI: https://doi.org/10.4049/jimmunol.190.Supp.138.3

Published: 01 May 2013

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Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells

Hiroki Tsukamoto, Kenji Fukudome, Shoko Takao, Naoko Tsuneyoshi, Shoichiro Ohta, Yoshinori Nagai, Hideyuki Ihara, Kensuke Miyake, Yoshitaka Ikeda, Masao Kimoto

J Immunol (2013) 190 (1): 195–204.

DOI: https://doi.org/10.4049/jimmunol.1201047

Published: 01 January 2013

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The Radioprotective 105/MD-1 Complex Contributes to Diet-induced Obesity and Adipose Tissue Inflammation (172.23)

Yasuharu Watanabe, Yoshinori Nagai, Tomoya Nakamura, Shizuo Akira, Kensuke Miyake, Kiyoshi Takatsu

J Immunol (2012) 188 (1_Supplement): 172.23.

DOI: https://doi.org/10.4049/jimmunol.188.Supp.172.23

Published: 01 May 2012

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A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells

Akihiko Murata, Kazuki Okuyama, Seiji Sakano, Masahiro Kajiki, Tomohisa Hirata, Hideo Yagita, Juan Carlos Zúñiga-Pflücker, Kensuke Miyake, Sachiko Akashi-Takamura, Sawako Moriwaki, Shumpei Niida, Miya Yoshino, Shin-Ichi Hayashi

J Immunol (2010) 185 (7): 3905–3912.

DOI: https://doi.org/10.4049/jimmunol.1000195

Published: 01 October 2010

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Molecular basis of regulatory effect of medicinal plant components on the innate immune response through TLR4 signaling (89.1)

Hiroe Honda, Yoshinori Nagai, Kensuke Miyake, Kiyoshi Takatsu

J Immunol (2010) 184 (1_Supplement): 89.1.

DOI: https://doi.org/10.4049/jimmunol.184.Supp.89.1

Published: 01 April 2010

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TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells (135.4)

Yoshinori Nagai, Shoichiro Ohta, Kensuke Miyake, Kiyoshi Takatsu

J Immunol (2009) 182 (1_Supplement): 135.4.

DOI: https://doi.org/10.4049/jimmunol.182.Supp.135.4

Published: 01 April 2009

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A Protein Associated with Toll-Like Receptor 4 (PRAT4A) Regulates Cell Surface Expression of TLR4

Yasutaka Wakabayashi, Makiko Kobayashi, Sachiko Akashi-Takamura, Natsuko Tanimura, Kazunori Konno, Koichiro Takahashi, Takashi Ishii, Taketoshi Mizutani, Hideo Iba, Taku Kouro, Satoshi Takaki, Kiyoshi Takatsu, Yoshiya Oda, Yasushi Ishihama, Shin-ichiroh Saitoh, Kensuke Miyake

J Immunol (2006) 177 (3): 1772–1779.

DOI: https://doi.org/10.4049/jimmunol.177.3.1772

Published: 01 August 2006

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MD1 Expression Regulates Development of Regulatory T Cells

Reginald M Gorczynski, Yu Kai, Kensuke Miyake

J Immunol (2006) 177 (2): 1078–1084.

DOI: https://doi.org/10.4049/jimmunol.177.2.1078

Published: 15 July 2006

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Regulatory Roles for MD-2 and TLR4 in Ligand-Induced Receptor Clustering

Makiko Kobayashi, Shin-ichiroh Saitoh, Natsuko Tanimura, Koichiro Takahashi, Kiyoshi Kawasaki, Masahiro Nishijima, Yukari Fujimoto, Koichi Fukase, Sachiko Akashi-Takamura, Kensuke Miyake

J Immunol (2006) 176 (10): 6211–6218.

DOI: https://doi.org/10.4049/jimmunol.176.10.6211

Published: 15 May 2006

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Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α

Sachiko Akashi-Takamura, Takahisa Furuta, Koichiro Takahashi, Natsuko Tanimura, Yutaka Kusumoto, Toshihiko Kobayashi, Shin-ichiroh Saitoh, Yoshiyuki Adachi, Takahiro Doi, Kensuke Miyake

J Immunol (2006) 176 (7): 4244–4251.

DOI: https://doi.org/10.4049/jimmunol.176.7.4244

Published: 01 April 2006

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The Radioprotective 105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes

Yoshinori Nagai, Toshihiko Kobayashi, Yuji Motoi, Kohtaroh Ishiguro, Sachiko Akashi, Shin-ichiroh Saitoh, Yutaka Kusumoto, Tsuneyasu Kaisho, Shizuo Akira, Mitsuru Matsumoto, Kiyoshi Takatsu, Kensuke Miyake

J Immunol (2005) 174 (11): 7043–7049.

DOI: https://doi.org/10.4049/jimmunol.174.11.7043

Published: 01 June 2005

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Interaction of Soluble Form of Recombinant Extracellular TLR4 Domain with MD-2 Enables Lipopolysaccharide Binding and Attenuates TLR4-Mediated Signaling

Naoki Hyakushima, Hiroaki Mitsuzawa, Chiaki Nishitani, Hitomi Sano, Koji Kuronuma, Masanori Konishi, Tetsuo Himi, Kensuke Miyake, Yoshio Kuroki

J Immunol (2004) 173 (11): 6949–6954.

DOI: https://doi.org/10.4049/jimmunol.173.11.6949

Published: 01 December 2004

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NARROW

6-Methyladenine may enhance immunostimulatory activity of bacterial genomic DNA

Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA

Type I IFN Contributes to the Phenotype of Unc93b1^D34A/D34A Mice by Regulating TLR7 Expression in B Cells and Dendritic Cells

Species-Specific Minimal Sequence Motif for Oligodeoxyribonucleotides Activating Mouse TLR9

Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses

Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses

Roles of the Cleaved N-Terminal TLR3 Fragment and Cell Surface TLR3 in Double-Stranded RNA Sensing

Serum Amyloid A3 Binds MD-2 To Activate p38 and NF-κB Pathways in a MyD88-Dependent Manner

Differential requirements of CD14 and Lipopolysaccharide Binding Protein in Monophosphoryl lipid A-mediated TLR4 activation (P1209)

Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells

The Radioprotective 105/MD-1 Complex Contributes to Diet-induced Obesity and Adipose Tissue Inflammation (172.23)

A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells

Molecular basis of regulatory effect of medicinal plant components on the innate immune response through TLR4 signaling (89.1)

TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells (135.4)

A Protein Associated with Toll-Like Receptor 4 (PRAT4A) Regulates Cell Surface Expression of TLR4

MD1 Expression Regulates Development of Regulatory T Cells

Regulatory Roles for MD-2 and TLR4 in Ligand-Induced Receptor Clustering

Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α

The Radioprotective 105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes

Interaction of Soluble Form of Recombinant Extracellular TLR4 Domain with MD-2 Enables Lipopolysaccharide Binding and Attenuates TLR4-Mediated Signaling

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