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A Noncanonical CD56^dimCD16^dim/− NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases

Soumya S. Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L. Bennett, Richard J. Nowak, Elias S. Sotirchos, Erin E. Longbrake, Emily M. Mace, Kevin C. O’Connor

J Immunol (2024) 212 (5): 785–800.

https://doi.org/10.4049/jimmunol.2300015

Published: 22 January 2024

View article titled, A Noncanonical CD56dimCD16dim/− NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases

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Includes: Supplementary data

Journal Articles

Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes

Caleigh Mandel-Brehm, Miriam L. Fichtner, Ruoyi Jiang, Valerie J. Winton, Sara E. Vazquez, Minh C. Pham, Kenneth B. Hoehn, Neil L. Kelleher, Richard J. Nowak, Steven H. Kleinstein, Michael R. Wilson, Joseph L. DeRisi, Kevin C. O’Connor

J Immunol (2021) 207 (8): 2005–2014.

https://doi.org/10.4049/jimmunol.2100225

Published: 15 October 2021

View article titled, Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes

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Includes: Supplementary data

Journal Articles

Monovalent IgG4 autoantibodies require self-antigen driven affinity maturation to acquire pathogenic capacity

Miriam F L Fichtner, Casey Vieni, Rachel L. Redler, Ruoyi Jiang, Pablo Suarez, Richard Nowak, Steven J Burden, Gira Bhabha, Damian C Ekiert, Kevin C O’Connor

J Immunol (2020) 204 (1_Supplement): 224.39.

https://doi.org/10.4049/jimmunol.204.Supp.224.39

Published: 01 May 2020

View article titled, Monovalent IgG4 autoantibodies require self-antigen driven affinity maturation to acquire pathogenic capacity

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Journal Articles

Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD⁻CD27⁻ Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients

Judith Fraussen, Susanna Marquez, Kazushiro Takata, Lien Beckers, Gwendoline Montes Diaz, Chrysoula Zografou, Bart Van Wijmeersch, Luisa M. Villar, Kevin C. O’Connor, Steven H. Kleinstein, Veerle Somers

J Immunol (2019) 203 (6): 1650–1664.

https://doi.org/10.4049/jimmunol.1801236

Published: 15 September 2019

View article titled, Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD−CD27− Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients

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Includes: Supplementary data

Journal Articles

Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity

Panos Stathopoulos, Anne Chastre, Patrick Waters, Sarosh Irani, Miriam L. Fichtner, Erik S. Benotti, Joel M. Guthridge, Jennifer Seifert, Richard J. Nowak, Jane H. Buckner, V. Michael Holers, Judith A. James, David A. Hafler, Kevin C. O’Connor

J Immunol (2019) 202 (8): 2210–2219.

https://doi.org/10.4049/jimmunol.1801295

Published: 15 April 2019

View article titled, Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity

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Includes: Supplementary data

Journal Articles

Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing

Jason A. Vander Heiden, Panos Stathopoulos, Julian Q. Zhou, Luan Chen, Tamara J. Gilbert, Christopher R. Bolen, Richard J. Barohn, Mazen M. Dimachkie, Emma Ciafaloni, Teresa J. Broering, Francois Vigneault, Richard J. Nowak, Steven H. Kleinstein, Kevin C. O’Connor

J Immunol (2017) 198 (4): 1460–1473.

https://doi.org/10.4049/jimmunol.1601415

Published: 15 February 2017

View article titled, Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing

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Includes: Supplementary data

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A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data

Ang Cui, Roberto Di Niro, Jason A. Vander Heiden, Adrian W. Briggs, Kris Adams, Tamara Gilbert, Kevin C. O’Connor, Francois Vigneault, Mark J. Shlomchik, Steven H. Kleinstein

J Immunol (2016) 197 (9): 3566–3574.

https://doi.org/10.4049/jimmunol.1502263

Published: 01 November 2016

View article titled, A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data

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Includes: Supplementary data

Journal Articles

Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production

Yonghao Cao, Robert A. Amezquita, Steven H. Kleinstein, Panos Stathopoulos, Richard J. Nowak, Kevin C. O’Connor

J Immunol (2016) 196 (5): 2075–2084.

https://doi.org/10.4049/jimmunol.1501339

Published: 01 March 2016

View article titled, Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production

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Includes: Supplementary data

Journal Articles

Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

J Immunol (2009) 183 (6): 4067–4076.

https://doi.org/10.4049/jimmunol.0801888

Published: 15 September 2009

View article titled, Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

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Includes: Supplementary data

Journal Articles

The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response

Simon N. Willis, Scott S. Mallozzi, Scott J. Rodig, Katherine M. Cronk, Shannon L. McArdel, Tyler Caron, Geraldine S. Pinkus, Laura Lovato, Kimberly L. Shampain, David E. Anderson, Richard C. E. Anderson, Jeffrey N. Bruce, Kevin C. O’Connor

J Immunol (2009) 182 (5): 3310–3317.

https://doi.org/10.4049/jimmunol.0803424

Published: 01 March 2009

View article titled, The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response

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Journal Articles

A Local Antigen-Driven Humoral Response Is Present in the Inflammatory Myopathies

Elizabeth M. Bradshaw, Ana Orihuela, Shannon L. McArdel, Mohammad Salajegheh, Anthony A. Amato, David A. Hafler, Steven A. Greenberg, Kevin C. O’Connor

J Immunol (2007) 178 (1): 547–556.

https://doi.org/10.4049/jimmunol.178.1.547

Published: 01 January 2007

View article titled, A Local Antigen-Driven Humoral Response Is Present in the Inflammatory Myopathies

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Journal Articles

Antibodies from Inflamed Central Nervous System Tissue Recognize Myelin Oligodendrocyte Glycoprotein

Kevin C. O’Connor, Heiner Appel, Lisa Bregoli, Matthew E. Call, Ingrid Catz, Jennifer A. Chan, Nicole H. Moore, Kenneth G. Warren, Susan J. Wong, David A. Hafler, Kai W. Wucherpfennig

J Immunol (2005) 175 (3): 1974–1982.

https://doi.org/10.4049/jimmunol.175.3.1974

Published: 01 August 2005

View article titled, Antibodies from Inflamed Central Nervous System Tissue Recognize Myelin Oligodendrocyte Glycoprotein

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Journal Articles

Immunological Memory: Contribution of Memory B Cells Expressing Costimulatory Molecules in the Resting State

Amit Bar-Or, Enedina M. L Oliveira, David E. Anderson, Jeff I. Krieger, Martin Duddy, Kevin C. O’Connor, David A. Hafler

J Immunol (2001) 167 (10): 5669–5677.

https://doi.org/10.4049/jimmunol.167.10.5669

Published: 15 November 2001

View article titled, Immunological Memory: Contribution of Memory B Cells Expressing Costimulatory Molecules in the Resting State

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Journal Articles

The Rearranged V_H Domain of a Physiologically Selected Anti-Single-Stranded DNA Antibody as a Precursor for Formation of IgM and IgG Antibodies to Diverse Antigens

Jing Li, Luis Fernandez, Kevin C. O’Connor, Thereza Imanishi-Kari, B. David Stollar

J Immunol (2001) 167 (7): 3746–3755.

https://doi.org/10.4049/jimmunol.167.7.3746

Published: 01 October 2001

View article titled, The Rearranged VH Domain of a Physiologically Selected Anti-Single-Stranded DNA Antibody as a Precursor for Formation of IgM and IgG Antibodies to Diverse Antigens

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NARROW

A Noncanonical CD56^dimCD16^dim/− NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases

Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes

Monovalent IgG4 autoantibodies require self-antigen driven affinity maturation to acquire pathogenic capacity

Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD⁻CD27⁻ Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients

Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity

Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing

A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data

Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production

Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

The Microenvironment of Germ Cell Tumors Harbors a Prominent Antigen-Driven Humoral Response

A Local Antigen-Driven Humoral Response Is Present in the Inflammatory Myopathies

Antibodies from Inflamed Central Nervous System Tissue Recognize Myelin Oligodendrocyte Glycoprotein

Immunological Memory: Contribution of Memory B Cells Expressing Costimulatory Molecules in the Resting State

The Rearranged V_H Domain of a Physiologically Selected Anti-Single-Stranded DNA Antibody as a Precursor for Formation of IgM and IgG Antibodies to Diverse Antigens

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