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Kevin L. Legge
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Journal Articles

Prefusion F–Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus

Free
Laura M. Stephens, Kathleen A. Ross, Kody A. Waldstein, Kevin L. Legge, Jason S. McLellan, Balaji Narasimhan, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2021) 206 (9): 2122–2134.
https://doi.org/10.4049/jimmunol.2100018
Published: 01 May 2021
View articletitled, Prefusion F–Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus
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Includes: Supplementary data
Journal Articles

Prefusion F-based polyanhydride nanovaccine induces robust humoral and cell-mediated immunity resulting in long-lasting protection against respiratory syncytial virus

Free
Laura Stephens, Kathleen A. Ross, Kevin L. Legge, Jason S. McLellan, Balaji Narasimhan, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 59.04.
https://doi.org/10.4049/jimmunol.206.Supp.59.04
Published: 01 May 2021
View articletitled, Prefusion F-based polyanhydride nanovaccine induces robust humoral and cell-mediated immunity resulting in long-lasting protection against respiratory syncytial virus
Add to Citation Manager for Prefusion F-based polyanhydride nanovaccine induces robust humoral and cell-mediated immunity resulting in long-lasting protection against respiratory syncytial virus
Journal Articles

Regulation of Th17 CD4 T Cell Responses During Pulmonary Group A Streptococcus (GAS) Infections by Dendritic cells

Free
Christopher Lopez, Zeb Zacharias, Kody Waldstein, Emma Hornick, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 65.02.
https://doi.org/10.4049/jimmunol.206.Supp.65.02
Published: 01 May 2021
View articletitled, Regulation of Th17 CD4 T Cell Responses During Pulmonary Group A Streptococcus (GAS) Infections by Dendritic cells
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Journal Articles

Chronic ethanol consumption increases susceptibility to influenza A virus infections via alteration of memory CD8 T cell responses

Free
Zeb Ralph Zacharias, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 65.08.
https://doi.org/10.4049/jimmunol.206.Supp.65.08
Published: 01 May 2021
View articletitled, Chronic ethanol consumption increases susceptibility to influenza A virus infections via alteration of memory CD8 T cell responses
Add to Citation Manager for Chronic ethanol consumption increases susceptibility to influenza A virus infections via alteration of memory CD8 T cell responses
Journal Articles

The Contribution of Pulmonary Dendritic Cells to the Induction and Regulation of T Cell Responses During Respiratory Infection

Free
Christopher Lopez, Zeb Raplh Zacharias, Kody Waldstein, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 85.14.
https://doi.org/10.4049/jimmunol.204.Supp.85.14
Published: 01 May 2020
View articletitled, The Contribution of Pulmonary Dendritic Cells to the Induction and Regulation of T Cell Responses During Respiratory Infection
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Journal Articles

Polyanhydride-based RSV prefusion F nanoparticle vaccine establishes lasting protection mediated by humoral and cellular immune responses

Free
Laura Stephens, Kathleen A. Ross, Stacey M. Hartwig, Jason S. McLellan, Balaji Narasimhan, Kevin L. Legge, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 166.3.
https://doi.org/10.4049/jimmunol.204.Supp.166.3
Published: 01 May 2020
View articletitled, Polyanhydride-based RSV prefusion F nanoparticle vaccine establishes lasting protection mediated by humoral and cellular immune responses
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Journal Articles

Chronic ethanol consumption causes lesions in CD8 T cell memory and is associated with increased susceptibility to influenza A virus infections

Free
Zeb Raplh Zacharias, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 93.4.
https://doi.org/10.4049/jimmunol.204.Supp.93.4
Published: 01 May 2020
View articletitled, Chronic ethanol consumption causes lesions in CD8 T cell memory and is associated with increased susceptibility to influenza A virus infections
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Journal Articles

Isoflavone Rich Diet Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) through Modulation of Gut Bacteria Depleted in Multiple Sclerosis Patients

Free
Samantha N Freedman, Shailesh K Shahi, Kasra Zarei, Arnav Gupta, Natalya V Guseva, Aaron D Bossler, Kevin L Legge, Ashutosh K Mangalam
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 141.12.
https://doi.org/10.4049/jimmunol.204.Supp.141.12
Published: 01 May 2020
View articletitled, Isoflavone Rich Diet Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) through Modulation of Gut Bacteria Depleted in Multiple Sclerosis Patients
Add to Citation Manager for Isoflavone Rich Diet Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) through Modulation of Gut Bacteria Depleted in Multiple Sclerosis Patients
Journal Articles

Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections

Free
Zeb R. Zacharias, Kevin L. Legge
Journal: The Journal of Immunology
J Immunol (2019) 203 (12): 3313–3324.
https://doi.org/10.4049/jimmunol.1900770
Published: 15 December 2019
View articletitled, Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections
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Includes: Supplementary data
Journal Articles

Robust immune response and protection generated by a polyanhydride-based nanoparticle vaccine utilizing the RSV prefusion F protein and/or M protein

Free
Laura Stephens, Kathleen A. Ross, Stacey M. Hartwig, Jason S. McLellan, Balaji Narasimhan, Kevin L. Legge, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 139.11.
https://doi.org/10.4049/jimmunol.202.Supp.139.11
Published: 01 May 2019
View articletitled, Robust immune response and protection generated by a polyanhydride-based nanoparticle vaccine utilizing the RSV prefusion F protein and/or M protein
Add to Citation Manager for Robust immune response and protection generated by a polyanhydride-based nanoparticle vaccine utilizing the RSV prefusion F protein and/or M protein
Journal Articles

Linking diet, gut microbiota and autoimmunity: A phytoestrogen diet alters the gut microbiota and influences Experimental Autoimmune Encephalomyelitis (EAE)

Free
Samantha N Freedman, Shailesh Shahi, Kasra Zarei, Arnav Gupta, Natalya Guseva, Aaron Bossler, Kevin L Legge, Ashutosh K Mangalam
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 178.13.
https://doi.org/10.4049/jimmunol.202.Supp.178.13
Published: 01 May 2019
View articletitled, Linking diet, gut microbiota and autoimmunity: A phytoestrogen diet alters the gut microbiota and influences Experimental Autoimmune Encephalomyelitis (EAE)
Add to Citation Manager for Linking diet, gut microbiota and autoimmunity: A phytoestrogen diet alters the gut microbiota and influences Experimental Autoimmune Encephalomyelitis (EAE)
Journal Articles

Nlrp12 mediates adverse neutrophil recruitment during influenza virus infection

Free
Emma Hornick, Balaji Banoth, Ann Miller, Zeb Ralph Zacharias, Nidhi Jain, Mary E. Wilson, Katherine Gibson-Corley, Kevin L. Legge, Gail A. Bishop, Fayyaz S. Sutterwala, Suzanne Cassel
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 60.3.
https://doi.org/10.4049/jimmunol.200.Supp.60.3
Published: 01 May 2018
View articletitled, Nlrp12 mediates adverse neutrophil recruitment during influenza virus infection
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Journal Articles

Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection

Free
Emma E. Hornick, Balaji Banoth, Ann M. Miller, Zeb R. Zacharias, Nidhi Jain, Mary E. Wilson, Katherine N. Gibson-Corley, Kevin L. Legge, Gail A. Bishop, Fayyaz S. Sutterwala, Suzanne L. Cassel
Journal: The Journal of Immunology
J Immunol (2018) 200 (3): 1188–1197.
https://doi.org/10.4049/jimmunol.1700999
Published: 01 February 2018
View articletitled, Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection
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Includes: Supplementary data
Journal Articles

B cells eliminate virus-specific CD8 T cells through a FasL:Fas dependent mechanism during high-dose influenza virus infections.

Free
Zeb Raplh Zacharias, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 77.17.
https://doi.org/10.4049/jimmunol.198.Supp.77.17
Published: 01 May 2017
View articletitled, B cells eliminate virus-specific CD8 T cells through a FasL:Fas dependent mechanism during high-dose influenza virus infections.
Add to Citation Manager for B cells eliminate virus-specific CD8 T cells through a FasL:Fas dependent mechanism during high-dose influenza virus infections.
Journal Articles

Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo

Free
Robert K. Strother, Derek B. Danahy, Dmitri I. Kotov, Tamara A. Kucaba, Zeb R. Zacharias, Thomas S. Griffith, Kevin L. Legge, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2016) 197 (11): 4301–4311.
https://doi.org/10.4049/jimmunol.1601463
Published: 01 December 2016
View articletitled, Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T Cell Responses In Vivo
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Includes: Supplementary data
Journal Articles

A unique subset of CD11c+ B cells upregulate FasL expression in response to IL-12p40 during lethal dose influenza virus (IAV) infections.

Free
Zeb Raplh Zacharias, Kevin L Legge
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 147.4.
https://doi.org/10.4049/jimmunol.196.Supp.147.4
Published: 01 May 2016
View articletitled, A unique subset of CD11c+ B cells upregulate FasL expression in response to IL-12p40 during lethal dose influenza virus (IAV) infections.
Add to Citation Manager for A unique subset of CD11c+ B cells upregulate FasL expression in response to IL-12p40 during lethal dose influenza virus (IAV) infections.
Journal Articles

Diet-Induced Obesity Does Not Impact the Generation and Maintenance of Primary Memory CD8 T Cells

Free
Shaniya H. Khan, Emily A. Hemann, Kevin L. Legge, Lyse A. Norian, Vladimir P. Badovinac
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 5873–5882.
https://doi.org/10.4049/jimmunol.1401685
Published: 15 December 2014
View articletitled, Diet-Induced Obesity Does Not Impact the Generation and Maintenance of Primary Memory CD8 T Cells
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Includes: Supplementary data
Journal Articles

Lymphopenia Associated with Highly Virulent H5N1 Virus Infection Due to Plasmacytoid Dendritic Cell–Mediated Apoptosis of T Cells

Free
Kobporn Boonnak, Leatrice Vogel, Friederike Feldmann, Heinz Feldmann, Kevin L. Legge, Kanta Subbarao
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5906–5912.
https://doi.org/10.4049/jimmunol.1302992
Published: 15 June 2014
View articletitled, Lymphopenia Associated with Highly Virulent H5N1 Virus Infection Due to Plasmacytoid Dendritic Cell–Mediated Apoptosis of T Cells
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Includes: Supplementary data
Journal Articles

Protective CD8 T Cell–Mediated Immunity against Influenza A Virus Infection following Influenza Virus–like Particle Vaccination

Free
Emily A. Hemann, Sang-Moo Kang, Kevin L. Legge
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2486–2494.
https://doi.org/10.4049/jimmunol.1300954
Published: 01 September 2013
View articletitled, Protective CD8 T Cell–Mediated Immunity against Influenza A Virus Infection following Influenza Virus–like Particle Vaccination
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Includes: Supplementary data
Journal Articles

The Magnitude of the T Cell Response to a Clinically Significant Dose of Influenza Virus Is Regulated by TRAIL

Free
Erik L. Brincks, Prajwal Gurung, Ryan A. Langlois, Emily A. Hemann, Kevin L. Legge, Thomas S. Griffith
Journal: The Journal of Immunology
J Immunol (2011) 187 (9): 4581–4588.
https://doi.org/10.4049/jimmunol.1002241
Published: 01 November 2011
View articletitled, The Magnitude of the T Cell Response to a Clinically Significant Dose of Influenza Virus Is Regulated by TRAIL
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Add to Citation Manager for The Magnitude of the T Cell Response to a Clinically Significant Dose of Influenza Virus Is Regulated by TRAIL
Includes: Supplementary data