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Kim E. Nichols
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Journal Articles

SAP-Mediated Inhibition of Diacylglycerol Kinase α Regulates TCR-Induced Diacylglycerol Signaling

Gianluca Baldanzi, Andrea Pighini, Valentina Bettio, Elena Rainero, Sara Traini, Federica Chianale, Paolo E. Porporato, Nicoletta Filigheddu, Riccardo Mesturini, Shuping Song, Tamas Schweighoffer, Laura Patrussi, Cosima T. Baldari, Xiao-Ping Zhong, Wim J. van Blitterswijk, Fabiola Sinigaglia, Kim E. Nichols, Ignacio Rubio, Ornella Parolini, Andrea Graziani
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5941–5951.
https://doi.org/10.4049/jimmunol.1002476
Published: 01 December 2011
View article titled, SAP-Mediated Inhibition of Diacylglycerol Kinase α Regulates TCR-Induced Diacylglycerol Signaling
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Includes: Supplementary data
Journal Articles

PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals

Damian Kovalovsky, Eric S. Alonzo, Olisambu U. Uche, Maggie Eidson, Kim E. Nichols, Derek B. Sant’Angelo
Journal: The Journal of Immunology
J Immunol (2010) 184 (12): 6746–6755.
https://doi.org/10.4049/jimmunol.1000776
Published: 15 June 2010
View article titled, PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals
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Journal Articles

Development of Promyelocytic Zinc Finger and ThPOK-Expressing Innate γδ T Cells Is Controlled by Strength of TCR Signaling and Id3

Eric S. Alonzo, Rachel A. Gottschalk, Joy Das, Takeshi Egawa, Robin M. Hobbs, Pier Paolo Pandolfi, Pablo Pereira, Kim E. Nichols, Gary A. Koretzky, Martha S. Jordan, Derek B. Sant’Angelo
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1268–1279.
https://doi.org/10.4049/jimmunol.0903218
Published: 28 December 2009
View article titled, Development of Promyelocytic Zinc Finger and ThPOK-Expressing Innate γδ T Cells Is Controlled by Strength of TCR Signaling and Id3
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Includes: Supplementary data
Journal Articles

The Adaptor Molecule Signaling Lymphocytic Activation Molecule-Associated Protein (SAP) Regulates IFN-γ and IL-4 Production in Vα14 Transgenic NKT Cells via Effects on GATA-3 and T-bet Expression

Osman Cen, Aki Ueda, Laura Guzman, Jimmy Jain, Hamid Bassiri, Kim E. Nichols, Paul L. Stein
Journal: The Journal of Immunology
J Immunol (2009) 182 (3): 1370–1378.
https://doi.org/10.4049/jimmunol.182.3.1370
Published: 01 February 2009
View article titled, The Adaptor Molecule Signaling Lymphocytic Activation Molecule-Associated Protein (SAP) Regulates IFN-γ and IL-4 Production in Vα14 Transgenic NKT Cells via Effects on GATA-3 and T-bet Expression
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Journal Articles

Differential Requirement for the SAP-Fyn Interaction during NK T Cell Development and Function

Selene Nunez-Cruz, W. C. Janice Yeo, Jennifer Rothman, Priti Ojha, Hamid Bassiri, Marisa Juntilla, Dominique Davidson, André Veillette, Gary A. Koretzky, Kim E. Nichols
Journal: The Journal of Immunology
J Immunol (2008) 181 (4): 2311–2320.
https://doi.org/10.4049/jimmunol.181.4.2311
Published: 15 August 2008
View article titled, Differential Requirement for the SAP-Fyn Interaction during NK T Cell Development and Function
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Journal Articles

Impaired SLAM-SLAM Homotypic Interaction between Invariant NKT Cells and Dendritic Cells Affects Differentiation of IL-4/IL-10-Secreting NKT2 Cells in Nonobese Diabetic Mice

Denis V. Baev, Simone Caielli, Francesca Ronchi, Margherita Coccia, Federica Facciotti, Kim E. Nichols, Marika Falcone
Journal: The Journal of Immunology
J Immunol (2008) 181 (2): 869–877.
https://doi.org/10.4049/jimmunol.181.2.869
Published: 15 July 2008
View article titled, Impaired SLAM-SLAM Homotypic Interaction between Invariant NKT Cells and Dendritic Cells Affects Differentiation of IL-4/IL-10-Secreting NKT2 Cells in Nonobese Diabetic Mice
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Journal Articles

Loss of SLP-76 Expression within Myeloid Cells Confers Resistance to Neutrophil-Mediated Tissue Damage while Maintaining Effective Bacterial Killing

Regina A. Clemens, Laurie E. Lenox, Taku Kambayashi, Natalie Bezman, Jonathan S. Maltzman, Kim E. Nichols, Gary A. Koretzky
Journal: The Journal of Immunology
J Immunol (2007) 178 (7): 4606–4614.
https://doi.org/10.4049/jimmunol.178.7.4606
Published: 01 April 2007
View article titled, Loss of SLP-76 Expression within Myeloid Cells Confers Resistance to Neutrophil-Mediated Tissue Damage while Maintaining Effective Bacterial Killing
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Journal Articles

Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii (51.16)

Cheng-hu Liu, Fabiana S. Machado, Rishu Guo, Kim E. Nichols, A. Wesley Burks, Julio C. Aliberti, Xiao-Ping Zhong
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S99.
https://doi.org/10.4049/jimmunol.178.Supp.51.16
Published: 01 April 2007
View article titled, Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii (51.16)
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Journal Articles

Expansion of Functionally Immature Transitional B Cells Is Associated with Human-Immunodeficient States Characterized by Impaired Humoral Immunity

Amanda K. Cuss, Danielle T. Avery, Jennifer L. Cannons, Li Jun Yu, Kim E. Nichols, Peter J. Shaw, Stuart G. Tangye
Journal: The Journal of Immunology
J Immunol (2006) 176 (3): 1506–1516.
https://doi.org/10.4049/jimmunol.176.3.1506
Published: 01 February 2006
View article titled, Expansion of Functionally Immature Transitional B Cells Is Associated with Human-Immunodeficient States Characterized by Impaired Humoral Immunity
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Journal Articles

SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation

Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols, Carl H. June, James L. Riley
Journal: The Journal of Immunology
J Immunol (2004) 173 (2): 945–954.
https://doi.org/10.4049/jimmunol.173.2.945
Published: 15 July 2004
View article titled, SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
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Journal Articles

Functional Requirements for Interactions Between CD84 and Src Homology 2 Domain-Containing Proteins and Their Contribution to Human T Cell Activation

Stuart G. Tangye, Kim E. Nichols, Nathan J. Hare, Barbara C. M. van de Weerdt
Journal: The Journal of Immunology
J Immunol (2003) 171 (5): 2485–2495.
https://doi.org/10.4049/jimmunol.171.5.2485
Published: 01 September 2003
View article titled, Functional Requirements for Interactions Between CD84 and Src Homology 2 Domain-Containing Proteins and Their Contribution to Human T Cell Activation
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Journal Articles

CD150 Association with Either the SH2-Containing Inositol Phosphatase or the SH2-Containing Protein Tyrosine Phosphatase Is Regulated by the Adaptor Protein SH2D1A

Larysa M. Shlapatska, Svitlana V. Mikhalap, Anna G. Berdova, Oleksander M. Zelensky, Theodore J. Yun, Kim E. Nichols, Edward A. Clark, Svetlana P. Sidorenko
Journal: The Journal of Immunology
J Immunol (2001) 166 (9): 5480–5487.
https://doi.org/10.4049/jimmunol.166.9.5480
Published: 01 May 2001
View article titled, CD150 Association with Either the SH2-Containing Inositol Phosphatase or the SH2-Containing Protein Tyrosine Phosphatase Is Regulated by the Adaptor Protein SH2D1A
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Journal Articles

Cutting Edge: Functional Requirement for SAP in 2B4-Mediated Activation of Human Natural Killer Cells as Revealed by the X-Linked Lymphoproliferative Syndrome

Stuart G. Tangye, Joseph H. Phillips, Lewis L. Lanier, Kim E. Nichols
Journal: The Journal of Immunology
J Immunol (2000) 165 (6): 2932–2936.
https://doi.org/10.4049/jimmunol.165.6.2932
Published: 15 September 2000
View article titled, Cutting Edge: Functional Requirement for SAP in 2B4-Mediated Activation of Human Natural Killer Cells as Revealed by the X-Linked Lymphoproliferative Syndrome
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Journal Articles

Molecular and Functional Characterization of Mouse Signaling Lymphocytic Activation Molecule (SLAM): Differential Expression and Responsiveness in Th1 and Th2 Cells

Antonio G. Castro, Thomas M. Hauser, Benjamin G. Cocks, John Abrams, Sandra Zurawski, Tatyana Churakova, Francesca Zonin, Douglas Robinson, Stuart G. Tangye, Gregorio Aversa, Kim E. Nichols, Jan E. de Vries, Lewis L. Lanier, Anne O’Garra
Journal: The Journal of Immunology
J Immunol (1999) 163 (11): 5860–5870.
https://doi.org/10.4049/jimmunol.163.11.5860
Published: 01 December 1999
View article titled, Molecular and Functional Characterization of Mouse Signaling Lymphocytic Activation Molecule (SLAM): Differential Expression and Responsiveness in Th1 and Th2 Cells
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