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Klaus Heeg
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Journal Articles

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism

Dominik Stammler, Tatjana Eigenbrod, Sarah Menz, Julia S. Frick, Matthew J. Sweet, Melanie R. Shakespear, Jonathan Jantsch, Isabel Siegert, Sabine Wölfle, Julian D. Langer, Ina Oehme, Liliana Schaefer, Andre Fischer, Judith Knievel, Klaus Heeg, Alexander H. Dalpke, Konrad A. Bode
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5421–5431.
https://doi.org/10.4049/jimmunol.1501195
Published: 01 December 2015
View article titled, Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism
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Includes: Supplementary data
Journal Articles

Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10–Producing B Cells in Response to Staphylococcus aureus

Marijo Parcina, María Auxiliadora Miranda-Garcia, Sibel Durlanik, Saskia Ziegler, Benjamin Over, Philipp Georg, Sandra Foermer, Sandra Ammann, Dina Hilmi, Klaus-Josef Weber, Martin Schiller, Klaus Heeg, Wulf Schneider-Brachert, Friedrich Götz, Isabelle Bekeredjian-Ding
Journal: The Journal of Immunology
J Immunol (2013) 190 (4): 1591–1602.
https://doi.org/10.4049/jimmunol.1201222
Published: 15 February 2013
View article titled, Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10–Producing B Cells in Response to <em>Staphylococcus aureus</em>
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Includes: Supplementary data
Journal Articles

Induction of Type I IFN Is a Physiological Immune Reaction to Apoptotic Cell-Derived Membrane Microparticles

Martin Schiller, Marijo Parcina, Petra Heyder, Sandra Foermer, Jenny Ostrop, Albrecht Leo, Klaus Heeg, Martin Herrmann, Hanns-Martin Lorenz, Isabelle Bekeredjian-Ding
Journal: The Journal of Immunology
J Immunol (2012) 189 (4): 1747–1756.
https://doi.org/10.4049/jimmunol.1100631
Published: 15 August 2012
View article titled, Induction of Type I IFN Is a Physiological Immune Reaction to Apoptotic Cell-Derived Membrane Microparticles
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Journal Articles

Kinetic of RelA Activation Controls Magnitude of TLR-Mediated IL-12p40 Induction

Konrad A. Bode, Frank Schmitz, Leonardo Vargas, Klaus Heeg, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2009) 182 (4): 2176–2184.
https://doi.org/10.4049/jimmunol.0802560
Published: 15 February 2009
View article titled, Kinetic of RelA Activation Controls Magnitude of TLR-Mediated IL-12p40 Induction
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Journal Articles

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells

Isabelle Bekeredjian-Ding, Anne Doster, Martin Schiller, Petra Heyder, Hanns-Martin Lorenz, Burkhart Schraven, Ursula Bommhardt, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8267–8277.
https://doi.org/10.4049/jimmunol.181.12.8267
Published: 15 December 2008
View article titled, TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM<sup>+</sup> B Cells
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Journal Articles

Staphylococcus aureus-Induced Plasmacytoid Dendritic Cell Activation Is Based on an IgG-Mediated Memory Response

Marijo Parcina, Constanze Wendt, Friedrich Goetz, Rainer Zawatzky, Ulrich Zähringer, Klaus Heeg, Isabelle Bekeredjian-Ding
Journal: The Journal of Immunology
J Immunol (2008) 181 (6): 3823–3833.
https://doi.org/10.4049/jimmunol.181.6.3823
Published: 15 September 2008
View article titled, <em>Staphylococcus aureus-</em>Induced Plasmacytoid Dendritic Cell Activation Is Based on an IgG-Mediated Memory Response
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Journal Articles

Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference

Florian Eberle, Kerstin Gießler, Christopher Deck, Klaus Heeg, Mirjam Peter, Clemens Richert, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 3229–3237.
https://doi.org/10.4049/jimmunol.180.5.3229
Published: 01 March 2008
View article titled, Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference
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Journal Articles

Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells

Anja K. Mayer, Mario Muehmer, Jörg Mages, Katja Gueinzius, Christian Hess, Klaus Heeg, Robert Bals, Roland Lang, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2007) 178 (5): 3134–3142.
https://doi.org/10.4049/jimmunol.178.5.3134
Published: 01 March 2007
View article titled, Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells
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Includes: Supplementary data
Journal Articles

Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling

Stefan Zimmermann, Peter J. Murray, Klaus Heeg, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2006) 176 (3): 1840–1847.
https://doi.org/10.4049/jimmunol.176.3.1840
Published: 01 February 2006
View article titled, Induction of Suppressor of Cytokine Signaling-1 by <em>Toxoplasma gondii</em> Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling
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Journal Articles

Immunostimulatory CpG-DNA Activates Murine Microglia

Alexander H. Dalpke, Martin K.-H. Schäfer, Markus Frey, Stefan Zimmermann, Johannes Tebbe, Eberhard Weihe, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (2002) 168 (10): 4854–4863.
https://doi.org/10.4049/jimmunol.168.10.4854
Published: 15 May 2002
View article titled, Immunostimulatory CpG-DNA Activates Murine Microglia
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Journal Articles

Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs

Alexander H. Dalpke, Sandra Opper, Stefan Zimmermann, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (2001) 166 (12): 7082–7089.
https://doi.org/10.4049/jimmunol.166.12.7082
Published: 15 June 2001
View article titled, Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs
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Journal Articles

CpG-DNA-Mediated Transient Lymphadenopathy Is Associated with a State of Th1 Predisposition to Antigen-Driven Responses

Grayson B. Lipford, Tim Sparwasser, Stefan Zimmermann, Klaus Heeg, Hermann Wagner
Journal: The Journal of Immunology
J Immunol (2000) 165 (3): 1228–1235.
https://doi.org/10.4049/jimmunol.165.3.1228
Published: 01 August 2000
View article titled, CpG-DNA-Mediated Transient Lymphadenopathy Is Associated with a State of Th1 Predisposition to Antigen-Driven Responses
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Journal Articles

Increased Susceptibility to Postoperative Sepsis in Patients with Impaired Monocyte IL-12 Production

Thorsten Hensler, Claus-Dieter Heidecke, Heike Hecker, Klaus Heeg, Holger Bartels, Niko Zantl, Hermann Wagner, Jörg-Rüdiger Siewert, Bernhard Holzmann
Journal: The Journal of Immunology
J Immunol (1998) 161 (5): 2655–2659.
https://doi.org/10.4049/jimmunol.161.5.2655
Published: 01 September 1998
View article titled, Increased Susceptibility to Postoperative Sepsis in Patients with Impaired Monocyte IL-12 Production
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Journal Articles

Cutting Edge: CpG Oligodeoxynucleotides Trigger Protective and Curative Th1 Responses in Lethal Murine Leishmaniasis

Stefan Zimmermann, Oliver Egeter, Susanne Hausmann, Grayson B. Lipford, Martin Röcken, Hermann Wagner, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (1998) 160 (8): 3627–3630.
https://doi.org/10.4049/jimmunol.160.8.3627
Published: 15 April 1998
View article titled, Cutting Edge: CpG Oligodeoxynucleotides Trigger Protective and Curative Th1 Responses in Lethal Murine Leishmaniasis
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