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Kristin Ladell
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Journal Articles

Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells

Stephen Man, James E. Redman, Deborah L. Cross, David K. Cole, Ilona Can, Bethan Davies, Shaikh Shimaz Hashimdeen, Reiss Reid, Sian Llewellyn-Lacey, Kelly L. Miners, Kristin Ladell, Anya Lissina, Paul E. Brown, Linda Wooldridge, David A. Price, Pierre J. Rizkallah
Journal: The Journal of Immunology
J Immunol (2021) 207 (4): 1009–1017.
https://doi.org/10.4049/jimmunol.2000756
Published: 15 August 2021
View article titled, Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells
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Includes: Supplementary data
Journal Articles

T cell receptor repertoire features display universal rules for selection and plasticity in the functional CD4 T cell subsets

Sofya A Kasatskaya, Kristin Ladell, Evgeny S. Egorov, David A. Price, Dmitriy Chudakov
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 230.9.
https://doi.org/10.4049/jimmunol.204.Supp.230.9
Published: 01 May 2020
View article titled, T cell receptor repertoire features display universal rules for selection and plasticity in the functional CD4 T cell subsets
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Journal Articles

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

Corinne J. Smith, Vanessa Venturi, Maire F. Quigley, Holly Turula, Emma Gostick, Kristin Ladell, Brenna J. Hill, Danielle Himelfarb, Kylie M. Quinn, Hui Yee Greenaway, Thurston H. Y. Dang, Robert A. Seder, Daniel C. Douek, Ann B. Hill, Miles P. Davenport, David A. Price, Christopher M. Snyder
Journal: The Journal of Immunology
J Immunol (2020) 204 (1): 112–121.
https://doi.org/10.4049/jimmunol.1900455
Published: 01 January 2020
View article titled, Stochastic Expansions Maintain the Clonal Stability of CD8<sup>+</sup> T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus
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Includes: Supplementary data
Journal Articles

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells

Benjamin J. Meckiff, Kristin Ladell, James E. McLaren, Gordon B. Ryan, Alison M. Leese, Eddie A. James, David A. Price, Heather M. Long
Journal: The Journal of Immunology
J Immunol (2019) 203 (5): 1276–1287.
https://doi.org/10.4049/jimmunol.1900377
Published: 01 September 2019
View article titled, Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

James E. McLaren, Mathew Clement, Morgan Marsden, Kelly L. Miners, Sian Llewellyn-Lacey, Emma J. Grant, Anzelika Rubina, Silvia Gimeno Brias, Emma Gostick, Maria A. Stacey, Selinda J. Orr, Richard J. Stanton, Kristin Ladell, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 943–955.
https://doi.org/10.4049/jimmunol.1701757
Published: 01 February 2019
View article titled, IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
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Includes: Supplementary data
Journal Articles

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin

Michelle L. McCully, Kristin Ladell, Robert Andrews, Rhiannon E. Jones, Kelly L. Miners, Laureline Roger, Duncan M. Baird, Mark J. Cameron, Zita M. Jessop, Iain S. Whitaker, Eleri L. Davies, David A. Price, Bernhard Moser
Journal: The Journal of Immunology
J Immunol (2018) 200 (5): 1639–1650.
https://doi.org/10.4049/jimmunol.1701377
Published: 01 March 2018
View article titled, CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin
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Includes: Supplementary data
Journal Articles

HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection

Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, Paul A. Goepfert
Journal: The Journal of Immunology
J Immunol (2016) 196 (8): 3276–3286.
https://doi.org/10.4049/jimmunol.1502411
Published: 15 April 2016
View article titled, HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
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Includes: Supplementary data
Journal Articles

Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers

Christopher J. Holland, Garry Dolton, Martin Scurr, Kristin Ladell, Andrea J. Schauenburg, Kelly Miners, Florian Madura, Andrew K. Sewell, David A. Price, David K. Cole, Andrew J. Godkin
Journal: The Journal of Immunology
J Immunol (2015) 195 (12): 5827–5836.
https://doi.org/10.4049/jimmunol.1402787
Published: 15 December 2015
View article titled, Enhanced Detection of Antigen-Specific CD4<sup>+</sup> T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers
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Includes: Supplementary data
Journal Articles

Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease

Kristin Ladell, Mette D. Hazenberg, Mark Fitch, Claire Emson, Bridget K. McEvoy-Hein Asgarian, Jeff E. Mold, Corey Miller, Robert Busch, David A. Price, Marc K. Hellerstein, Joseph M. McCune
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4096–4105.
https://doi.org/10.4049/jimmunol.1500799
Published: 01 November 2015
View article titled, Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease
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Includes: Supplementary data
Journal Articles

Determinants of Gliadin-Specific T Cell Selection in Celiac Disease

Jan Petersen, Jeroen van Bergen, Khai Lee Loh, Yvonne Kooy-Winkelaar, Dennis X. Beringer, Allan Thompson, Sjoerd F. Bakker, Chris J. J. Mulder, Kristin Ladell, James E. McLaren, David A. Price, Jamie Rossjohn, Hugh H. Reid, Frits Koning
Journal: The Journal of Immunology
J Immunol (2015) 194 (12): 6112–6122.
https://doi.org/10.4049/jimmunol.1500161
Published: 15 June 2015
View article titled, Determinants of Gliadin-Specific T Cell Selection in Celiac Disease
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Includes: Supplementary data
Journal Articles

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

Henrik N. Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung’u, Søren Buus, David A. Price, Philip J. Goulder
Journal: The Journal of Immunology
J Immunol (2015) 194 (11): 5329–5345.
https://doi.org/10.4049/jimmunol.1400854
Published: 01 June 2015
View article titled, CD8<sup>+</sup> TCR Bias and Immunodominance in HIV-1 Infection
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Includes: Supplementary data
Journal Articles

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

Dan Koning, Ana I. Costa, Ilka Hoof, John J. Miles, Nening M. Nanlohy, Kristin Ladell, Katherine K. Matthews, Vanessa Venturi, Ingrid M. M. Schellens, Jose A. M. Borghans, Can Keşmir, David A. Price, Debbie van Baarle
Journal: The Journal of Immunology
J Immunol (2013) 190 (3): 931–939.
https://doi.org/10.4049/jimmunol.1202466
Published: 01 February 2013
View article titled, CD8<sup>+</sup> TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex
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Includes: Supplementary data
Journal Articles

Correction: Central Memory CD8+ T Cells Appear to Have a Shorter Lifespan and Reduced Abundance as a Function of HIV Disease Progression

Kristin Ladell, Marc K. Hellerstein, Denise Cesar, Robert Busch, Drina Boban, Joseph M. McCune
Journal: The Journal of Immunology
J Immunol (2012) 189 (10): 5089.
https://doi.org/10.4049/jimmunol.1290067
Published: 15 November 2012
View article titled, Correction: Central Memory CD8+ T Cells Appear to Have a Shorter Lifespan and Reduced Abundance as a Function of HIV Disease Progression
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Journal Articles

Anti-CD8 Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide–MHCI Tetramer Staining

Mathew Clement, Kristin Ladell, Julia Ekeruche-Makinde, John J. Miles, Emily S. J. Edwards, Garry Dolton, Tamsin Williams, Andrea J. A. Schauenburg, David K. Cole, Sarah N. Lauder, Awen M. Gallimore, Andrew J. Godkin, Scott R. Burrows, David A. Price, Andrew K. Sewell, Linda Wooldridge
Journal: The Journal of Immunology
J Immunol (2011) 187 (2): 654–663.
https://doi.org/10.4049/jimmunol.1003941
Published: 15 July 2011
View article titled, Anti-CD8 Antibodies Can Trigger CD8<sup>+</sup> T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide–MHCI Tetramer Staining
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Includes: Supplementary data
Journal Articles

Anti-CD8 antibodies can trigger T-cell effector function in the absence of TCR engagement and improve pMHCI tetramer staining (113.28)

Linda Wooldridge, Kristin Ladell, David Price, Andrew Sewell, Mathew Clement
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 113.28.
https://doi.org/10.4049/jimmunol.186.Supp.113.28
Published: 01 April 2011
View article titled, Anti-CD8 antibodies can trigger T-cell effector function in the absence of TCR engagement and improve pMHCI tetramer staining (113.28)
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Journal Articles

Persistent Survival of Prevalent Clonotypes within an Immunodominant HIV Gag-Specific CD8+ T Cell Response

David J. van Bockel, David A. Price, Mee Ling Munier, Vanessa Venturi, Tedi E. Asher, Kristin Ladell, Hui Yee Greenaway, John Zaunders, Daniel C. Douek, David A. Cooper, Miles P. Davenport, Anthony D. Kelleher
Journal: The Journal of Immunology
J Immunol (2011) 186 (1): 359–371.
https://doi.org/10.4049/jimmunol.1001807
Published: 01 January 2011
View article titled, Persistent Survival of Prevalent Clonotypes within an Immunodominant HIV Gag-Specific CD8<sup>+</sup> T Cell Response
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Journal Articles

IL-10 Restricts Memory T Cell Inflation during Cytomegalovirus Infection

Morgan Jones, Kristin Ladell, Katherine K. Wynn, Maria A. Stacey, Máire F. Quigley, Emma Gostick, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2010) 185 (6): 3583–3592.
https://doi.org/10.4049/jimmunol.1001535
Published: 15 September 2010
View article titled, IL-10 Restricts Memory T Cell Inflation during Cytomegalovirus Infection
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Includes: Supplementary data
Journal Articles

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

David K. Cole, Emily S. J. Edwards, Katherine K. Wynn, Mathew Clement, John J. Miles, Kristin Ladell, Julia Ekeruche, Emma Gostick, Katherine J. Adams, Ania Skowera, Mark Peakman, Linda Wooldridge, David A. Price, Andrew K. Sewell
Journal: The Journal of Immunology
J Immunol (2010) 185 (4): 2600–2610.
https://doi.org/10.4049/jimmunol.1000629
Published: 15 August 2010
View article titled, Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition
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Journal Articles

MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs

Linda Wooldridge, Mathew Clement, Anna Lissina, Emily S. J. Edwards, Kristin Ladell, Julia Ekeruche, Rachel E. Hewitt, Bruno Laugel, Emma Gostick, David K. Cole, Reno Debets, Cor Berrevoets, John J. Miles, Scott R. Burrows, David A. Price, Andrew K. Sewell
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3357–3366.
https://doi.org/10.4049/jimmunol.0902398
Published: 01 April 2010
View article titled, MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs
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Journal Articles

TCR β-Chain Sharing in Human CD8+ T Cell Responses to Cytomegalovirus and EBV

Vanessa Venturi, Hui Yee Chin, Tedi E. Asher, Kristin Ladell, Phillip Scheinberg, Ethan Bornstein, David van Bockel, Anthony D. Kelleher, Daniel C. Douek, David A. Price, Miles P. Davenport
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7853–7862.
https://doi.org/10.4049/jimmunol.181.11.7853
Published: 01 December 2008
View article titled, TCR β-Chain Sharing in Human CD8<sup>+</sup> T Cell Responses to Cytomegalovirus and EBV
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Includes: Supplementary data