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Lars Nitschke
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Journal Articles

CD22 Controls Germinal Center B Cell Receptor Signaling, Which Influences Plasma Cell and Memory B Cell Output

Sarah J. Meyer, Marie Steffensen, Andreas Acs, Thomas Weisenburger, Charlotte Wadewitz, Thomas H. Winkler, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2021) 207 (4): 1018–1032.
https://doi.org/10.4049/jimmunol.2100132
Published: 15 August 2021
View article titled, CD22 Controls Germinal Center B Cell Receptor Signaling, Which Influences Plasma Cell and Memory B Cell Output
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Includes: Supplementary data
Journal Articles

Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis

Marina A. Korn, Heike Schmitt, Sieglinde Angermüller, David Chambers, Michaela Seeling, Uwe T. Lux, Stefanie Brey, Dmytro Royzman, Christin Brückner, Vanessa Popp, Elena Percivalle, Tobias Bäuerle, Elisabeth Zinser, Thomas H. Winkler, Alexander Steinkasserer, Falk Nimmerjahn, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2020) 205 (10): 2595–2605.
https://doi.org/10.4049/jimmunol.2000472
Published: 15 November 2020
View article titled, Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis
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Includes: Supplementary data
Journal Articles

Cullin 3 Is Crucial for Pro-B Cell Proliferation, Interacts with CD22, and Controls CD22 Internalization on B Cells

Sarah J. Meyer, Alexander Böser, Marina A. Korn, Claudia Koller, Barbara Bertocci, Lena Reimann, Bettina Warscheid, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2020) 204 (12): 3360–3374.
https://doi.org/10.4049/jimmunol.1900925
Published: 15 June 2020
View article titled, Cullin 3 Is Crucial for Pro-B Cell Proliferation, Interacts with CD22, and Controls CD22 Internalization on B Cells
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Includes: Supplementary data
Journal Articles

Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction

Lamia Özgör, Sarah J. Meyer, Marina Korn, Klara Terörde, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2018) 201 (7): 2107–2116.
https://doi.org/10.4049/jimmunol.1800296
Published: 01 October 2018
View article titled, Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction
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Includes: Supplementary data
Journal Articles

CD83 Modulates B Cell Activation and Germinal Center Responses

Lena Krzyzak, Christine Seitz, Anne Urbat, Stefan Hutzler, Christian Ostalecki, Joachim Gläsner, Andreas Hiergeist, André Gessner, Thomas H. Winkler, Alexander Steinkasserer, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2016) 196 (9): 3581–3594.
https://doi.org/10.4049/jimmunol.1502163
Published: 01 May 2016
View article titled, CD83 Modulates B Cell Activation and Germinal Center Responses
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Includes: Supplementary data
Journal Articles

Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis

Daniel Radtke, Sonja M. Lacher, Nadine Szumilas, Lena Sandrock, Jochen Ackermann, Lars Nitschke, Elisabeth Zinser
Journal: The Journal of Immunology
J Immunol (2016) 196 (7): 2995–3005.
https://doi.org/10.4049/jimmunol.1501764
Published: 01 April 2016
View article titled, Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis
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Includes: Supplementary data
Journal Articles

Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice

Jennifer Müller, Benjamin Lunz, Inessa Schwab, Andreas Acs, Falk Nimmerjahn, Christoph Daniel, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2015) 195 (1): 51–60.
https://doi.org/10.4049/jimmunol.1403139
Published: 01 July 2015
View article titled, Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice
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Includes: Supplementary data
Journal Articles

Dickkopf-3 Acts as a Modulator of B Cell Fate and Function

Julia Ludwig, Giuseppina Federico, Sandra Prokosch, Günter Küblbeck, Sabine Schmitt, Alexandra Klevenz, Hermann-Josef Gröne, Lars Nitschke, Bernd Arnold
Journal: The Journal of Immunology
J Immunol (2015) 194 (6): 2624–2634.
https://doi.org/10.4049/jimmunol.1402160
Published: 15 March 2015
View article titled, Dickkopf-3 Acts as a Modulator of B Cell Fate and Function
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Includes: Supplementary data
Journal Articles

A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels

Wei Luo, Jessica Mayeux, Toni Gutierrez, Lisa Russell, Andrew Getahun, Jennifer Müller, Thomas Tedder, Jane Parnes, Robert Rickert, Lars Nitschke, John Cambier, Anne B. Satterthwaite, Lee Ann Garrett-Sinha
Journal: The Journal of Immunology
J Immunol (2014) 193 (2): 909–920.
https://doi.org/10.4049/jimmunol.1400666
Published: 15 July 2014
View article titled, A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels
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Includes: Supplementary data
Journal Articles

The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells

Stefan Hutzler, Lamia Özgör, Yuko Naito-Matsui, Kathrin Kläsener, Thomas H. Winkler, Michael Reth, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2014) 192 (11): 5406–5414.
https://doi.org/10.4049/jimmunol.1302875
Published: 01 June 2014
View article titled, The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells
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Includes: Supplementary data
Journal Articles

A balance between BCR and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels (BA2P.120)

Wei Luo, Jessica Mayeux, Toni Gutierrez, Andy Getahun, Jennifer Müller, Thomas Tedder, Shu-Hsia Chen, Robert Rickert, Lars Nitschke, John Cambier, Anne Satterthwaite, Lee Ann Garrett-Sinha
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 45.7.
https://doi.org/10.4049/jimmunol.192.Supp.45.7
Published: 01 May 2014
View article titled, A balance between BCR and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels (BA2P.120)
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Journal Articles

Siglec-G Deficiency Leads to More Severe Collagen-Induced Arthritis and Earlier Onset of Lupus-like Symptoms in MRL/lpr Mice

Susanne Bökers, Anne Urbat, Christoph Daniel, Kerstin Amann, Kenneth G. C. Smith, Marion Espéli, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2014) 192 (7): 2994–3002.
https://doi.org/10.4049/jimmunol.1303367
Published: 01 April 2014
View article titled, Siglec-G Deficiency Leads to More Severe Collagen-Induced Arthritis and Earlier Onset of Lupus-like Symptoms in MRL<em>/lpr</em> Mice
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Journal Articles

Siglec-G Regulates B1 Cell Survival and Selection

Julia Jellusova, Sandra Düber, Eva Gückel, Christoph J. Binder, Siegfried Weiss, Reinhard Voll, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2010) 185 (6): 3277–3284.
https://doi.org/10.4049/jimmunol.1001792
Published: 15 September 2010
View article titled, Siglec-G Regulates B1 Cell Survival and Selection
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Includes: Supplementary data
Journal Articles

Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C γ2 in Membrane Rafts

Carmen Kroczek, Christiane Lang, Sebastian Brachs, Marcus Grohmann, Sebastian Dütting, Astrid Schweizer, Lars Nitschke, Stephan M. Feller, Hans-Martin Jäck, Dirk Mielenz
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3665–3676.
https://doi.org/10.4049/jimmunol.0903642
Published: 01 April 2010
View article titled, Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C γ2 in Membrane Rafts
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Includes: Supplementary data
Journal Articles

CD22 × Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity

Julia Jellusova, Ute Wellmann, Kerstin Amann, Thomas H. Winkler, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3618–3627.
https://doi.org/10.4049/jimmunol.0902711
Published: 01 April 2010
View article titled, CD22 × Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity
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Includes: Supplementary data
Journal Articles

Regulation of Repertoire Development through Genetic Control of DH Reading Frame Preference

Michael Zemlin, Robert L. Schelonka, Gregory C. Ippolito, Cosima Zemlin, Yingxin Zhuang, G. Larry Gartland, Lars Nitschke, Jukka Pelkonen, Klaus Rajewsky, Harry W. Schroeder, Jr.
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8416–8424.
https://doi.org/10.4049/jimmunol.181.12.8416
Published: 15 December 2008
View article titled, Regulation of Repertoire Development through Genetic Control of D<sub>H</sub> Reading Frame Preference
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Journal Articles

B Cell-Specific Deficiency for Smad2 In Vivo Leads to Defects in TGF-β-Directed IgA Switching and Changes in B Cell Fate

Jörg Klein, Wenjun Ju, Jörg Heyer, Britta Wittek, Torsten Haneke, Petra Knaus, Raju Kucherlapati, Erwin P. Böttinger, Lars Nitschke, Burkhard Kneitz
Journal: The Journal of Immunology
J Immunol (2006) 176 (4): 2389–2396.
https://doi.org/10.4049/jimmunol.176.4.2389
Published: 15 February 2006
View article titled, B Cell-Specific Deficiency for Smad2 In Vivo Leads to Defects in TGF-β-Directed IgA Switching and Changes in B Cell Fate
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Journal Articles

A Single DH Gene Segment Creates Its Own Unique CDR-H3 Repertoire and Is Sufficient for B cell Development and Immune Function

Robert L. Schelonka, Ivaylo I. Ivanov, David H. Jung, Gregory C. Ippolito, Lars Nitschke, Yingxin Zhuang, G. Larry Gartland, Jukka Pelkonen, Frederick W. Alt, Klaus Rajewsky, Harry W. Schroeder, Jr
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6624–6632.
https://doi.org/10.4049/jimmunol.175.10.6624
Published: 15 November 2005
View article titled, A Single D<sub>H</sub> Gene Segment Creates Its Own Unique CDR-H3 Repertoire and Is Sufficient for B cell Development and Immune Function
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Includes: Supplementary data
Journal Articles

B Cell Hyperresponsiveness and Expansion of Mature Follicular B Cells but Not of Marginal Zone B Cells in NFATc2/c3 Double-Deficient Mice

Devapriya Nandini Samanta, Alois Palmetshofer, Dragan Marinkovic, Thomas Wirth, Edgar Serfling, Lars Nitschke
Journal: The Journal of Immunology
J Immunol (2005) 174 (8): 4797–4802.
https://doi.org/10.4049/jimmunol.174.8.4797
Published: 15 April 2005
View article titled, B Cell Hyperresponsiveness and Expansion of Mature Follicular B Cells but Not of Marginal Zone B Cells in NFATc2/c3 Double-Deficient Mice
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Journal Articles

A Critical Role for FcγRIIB in the Induction of Rheumatoid Factors

Thomas Moll, Lars Nitschke, Michael Carroll, Jeffrey V. Ravetch, Shozo Izui
Journal: The Journal of Immunology
J Immunol (2004) 173 (7): 4724–4728.
https://doi.org/10.4049/jimmunol.173.7.4724
Published: 01 October 2004
View article titled, A Critical Role for FcγRIIB in the Induction of Rheumatoid Factors
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