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Laurence A. Turka
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Journal Articles

Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance

Simon Glatigny, Barbara Höllbacher, Samantha J. Motley, Cathy Tan, Christian Hundhausen, Jane H. Buckner, Dawn Smilek, Samia J. Khoury, Linna Ding, Tielin Qin, Jorge Pardo, Gerald T. Nepom, Laurence A. Turka, Kristina M. Harris, Daniel J. Campbell, Estelle Bettelli
Journal: The Journal of Immunology
J Immunol (2019) 202 (5): 1373–1382.
DOI: https://doi.org/10.4049/jimmunol.1801425
Published: 01 March 2019
View article titled, Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance
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Includes: Supplementary data
Journal Articles

Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets

Bhavana Priyadharshini, Michael Loschi, Ryan H. Newton, Jian-Wen Zhang, Kelsey K. Finn, Valerie A. Gerriets, Alexandria Huynh, Jeffery C. Rathmell, Bruce R. Blazar, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2018) 201 (8): 2215–2219.
DOI: https://doi.org/10.4049/jimmunol.1800311
Published: 15 October 2018
View article titled, Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets
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Includes: Supplementary data
Journal Articles

Tumor Tolerance–Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin

Francesco Marangoni, Ruan Zhang, Vinidhra Mani, Martin Thelen, Noor J. Ali Akbar, Ross D. Warner, Tarmo Äijö, Valentina Zappulli, Gustavo J. Martinez, Laurence A. Turka, Thorsten R. Mempel
Journal: The Journal of Immunology
J Immunol (2018) 200 (10): 3647–3661.
DOI: https://doi.org/10.4049/jimmunol.1701220
Published: 15 May 2018
View article titled, Tumor Tolerance–Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin
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Includes: Supplementary data
Journal Articles

Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells

Ruan Zhang, Peter T. Sage, Kelsey Finn, Alexandria Huynh, Bruce R. Blazar, Francesco Marangoni, Thorsten R. Mempel, Arlene H. Sharpe, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2018) 200 (7): 2505–2506.
DOI: https://doi.org/10.4049/jimmunol.1800150
Published: 01 April 2018
View article titled, Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells
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Journal Articles

B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells

Ruan Zhang, Peter T. Sage, Kelsey Finn, Alexandria Huynh, Bruce R. Blazar, Francesco Marangoni, Thorsten R. Mempel, Arlene H. Sharpe, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2017) 199 (12): 3972–3980.
DOI: https://doi.org/10.4049/jimmunol.1700409
Published: 15 December 2017
View article titled, B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells
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Includes: Supplementary data
Journal Articles

MHC class II-peptide complexes displayed on activated T cells guide Treg suppression

Sharon K Germana, Madeline L. Fryer, Steffie Junius, Laurence A Turka, Christian A LeGuern
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 80.10.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.80.10
Published: 01 May 2017
View article titled, MHC class II-peptide complexes displayed on activated T cells guide Treg suppression
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Journal Articles

Requirement for CD28 in Effector Regulatory T Cell Differentiation, CCR6 Induction, and Skin Homing

Ruan Zhang, Christopher M. Borges, Martin Y. Fan, John E. Harris, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4154–4161.
DOI: https://doi.org/10.4049/jimmunol.1500945
Published: 01 November 2015
View article titled, Requirement for CD28 in Effector Regulatory T Cell Differentiation, CCR6 Induction, and Skin Homing
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Includes: Supplementary data
Journal Articles

Interruption of Dendritic Cell–Mediated TIM-4 Signaling Induces Regulatory T Cells and Promotes Skin Allograft Survival

Melissa Y. Yeung, Martina M. McGrath, Masafumi Nakayama, Tetsunosuke Shimizu, Olaf Boenisch, Ciara N. Magee, Rozita Abdoli, Hisaya Akiba, Takuya Ueno, Laurence A. Turka, Nader Najafian
Journal: The Journal of Immunology
J Immunol (2013) 191 (8): 4447–4455.
DOI: https://doi.org/10.4049/jimmunol.1300992
Published: 15 October 2013
View article titled, Interruption of Dendritic Cell–Mediated TIM-4 Signaling Induces Regulatory T Cells and Promotes Skin Allograft Survival
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Includes: Supplementary data
Journal Articles

New Insights on OX40 in the Control of T Cell Immunity and Immune Tolerance In Vivo

Xiang Xiao, Weihua Gong, Gulcin Demirci, Wentao Liu, Silvia Spoerl, Xiufeng Chu, D. Keith Bishop, Laurence A. Turka, Xian C. Li
Journal: The Journal of Immunology
J Immunol (2012) 188 (2): 892–901.
DOI: https://doi.org/10.4049/jimmunol.1101373
Published: 15 January 2012
View article titled, New Insights on OX40 in the Control of T Cell Immunity and Immune Tolerance In Vivo
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Journal Articles

CTLA-4: Not All Costimulation Is Stimulatory

In Special Collection:
Pillars of Immunology
Hugh Auchincloss, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2011) 187 (7): 3457–3458.
DOI: https://doi.org/10.4049/jimmunol.1102316
Published: 01 October 2011
View article titled, CTLA-4: Not All Costimulation Is Stimulatory
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Journal Articles

Physical and Functional Bivalency Observed Among TCR/CD3 Complexes Isolated from Primary T Cells

Adam G. Schrum, Diana Gil, Laurence A. Turka, Ed Palmer
Journal: The Journal of Immunology
J Immunol (2011) 187 (2): 870–878.
DOI: https://doi.org/10.4049/jimmunol.1100538
Published: 15 July 2011
View article titled, Physical and Functional Bivalency Observed Among TCR/CD3 Complexes Isolated from Primary T Cells
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Journal Articles

A Role for IL-27 in Limiting T Regulatory Cell Populations

Elia D. Tait Wojno, Nancy Hosken, Jason S. Stumhofer, Aisling C. O’Hara, Elizabeth Mauldin, Qun Fang, Laurence A. Turka, Steven D. Levin, Christopher A. Hunter
Journal: The Journal of Immunology
J Immunol (2011) 187 (1): 266–273.
DOI: https://doi.org/10.4049/jimmunol.1004182
Published: 01 July 2011
View article titled, A Role for IL-27 in Limiting T Regulatory Cell Populations
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Includes: Supplementary data
Journal Articles

MyD88 expression in stem cells regulates hematopoietic reconstitution following bone marrow transplantation (138.16)

Adeeb H Rahman, Laurence A Turka
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 138.16.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.138.16
Published: 01 April 2009
View article titled, MyD88 expression in stem cells regulates hematopoietic reconstitution following bone marrow transplantation (138.16)
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Journal Articles

Biochemical evidence for bivalent T cell antigen receptor expression in primary T cells (35.42)

Adam G. Schrum, Laurence A. Turka, Ed Palmer
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 35.42.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.35.42
Published: 01 April 2009
View article titled, Biochemical evidence for bivalent T cell antigen receptor expression in primary T cells (35.42)
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Journal Articles

MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection

Adeeb H. Rahman, Weiguo Cui, David F. LaRosa, Devon K. Taylor, Jidong Zhang, Daniel R. Goldstein, E. John Wherry, Susan M. Kaech, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2008) 181 (6): 3804–3810.
DOI: https://doi.org/10.4049/jimmunol.181.6.3804
Published: 15 September 2008
View article titled, MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection
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Journal Articles

Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands

Paige M. Porrett, Xueli Yuan, David F. LaRosa, Patrick T. Walsh, Jaeseok Yang, Wenda Gao, Peiying Li, Jidong Zhang, Javeed M. Ansari, Wayne W. Hancock, Mohamed H. Sayegh, Maria Koulmanda, Terry B. Strom, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2008) 181 (3): 1692–1699.
DOI: https://doi.org/10.4049/jimmunol.181.3.1692
Published: 01 August 2008
View article titled, Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands
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Journal Articles

Cutting Edge: Requirement for TRAF6 in the Induction of T Cell Anergy

Carolyn G. King, Jodi L. Buckler, Takashi Kobayashi, Jeffrey R. Hannah, Garrett Bassett, Taesoo Kim, Erika L. Pearce, Gregory G. Kim, Laurence A. Turka, Yongwon Choi
Journal: The Journal of Immunology
J Immunol (2008) 180 (1): 34–38.
DOI: https://doi.org/10.4049/jimmunol.180.1.34
Published: 01 January 2008
View article titled, Cutting Edge: Requirement for TRAF6 in the Induction of T Cell Anergy
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Journal Articles

The Innate Immune System in Allograft Rejection and Tolerance

In Special Collection:
Brief Reviews
David F. LaRosa, Adeeb H. Rahman, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2007) 178 (12): 7503–7509.
DOI: https://doi.org/10.4049/jimmunol.178.12.7503
Published: 15 June 2007
View article titled, The Innate Immune System in Allograft Rejection and Tolerance
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Journal Articles

CD4 T cell expression of costimulatory receptors is directly enhanced by Toll-like receptor ligands (88.37)

Devon K Taylor, David F LaRosa, Adeeb H Rahman, Jidong zhang, Laurence A Turka
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S145–S146.
DOI: https://doi.org/10.4049/jimmunol.178.Supp.88.37
Published: 01 April 2007
View article titled, CD4 T cell expression of costimulatory receptors is directly enhanced by Toll-like receptor ligands (88.37)
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Journal Articles

A Novel Role for PTEN as a Regulator of T Cell Tolerance (128.27)

Jodi L. Buckler, Patrick T. Walsh, Laurence A. Turka
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S215.
DOI: https://doi.org/10.4049/jimmunol.178.Supp.128.27
Published: 01 April 2007
View article titled, A Novel Role for PTEN as a Regulator of T Cell Tolerance (128.27)
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