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Lawren C. Wu
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Journal Articles

Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFNα-accelerated lupus nephritis prone mice

Hans D Brightbill, Eric Suto, Nicole Blaquiere, Nandhini Ramamoorthi, Swathi Sujatha-Bhaskar, Emily Gogol, Georgette Castanedo, Benjamin Jackson, Susan Haller, Justin Lesch, Karin Bents, Christine Everett, Pawan Bir Kohli, Sandra Linge, Laura Christian, Kathy Barrett, Allan Jaochico, Leonid M Berezhkovskiy, Peter W Fan, Kelli Veliz, Michael Townsend, Jason DeVoss, Adam Johnson, Robert Godemann, Wyne P Lee, Cary D Austin, Brent McKenzie, Jason A Hackney, James J Crawford, Steven Staben, Moulay Hicham Alaoui Ismaili, Lawren C Wu, Nico Ghilardi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 217.4.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.217.4
Published: 01 May 2017
View article titled, Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFNα-accelerated lupus nephritis prone mice
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Journal Articles

A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma

Aarti Shikotra, David F. Choy, Salman Siddiqui, Greer Arthur, Deepti R. Nagarkar, Guiquan Jia, Adam K. A. Wright, Chandra M. Ohri, Emma Doran, Claire A. Butler, Beverley Hargadon, Alexander R. Abbas, Janet Jackman, Lawren C. Wu, Liam G. Heaney, Joseph R. Arron, Peter Bradding
Journal: The Journal of Immunology
J Immunol (2017) 198 (8): 3307–3317.
DOI: https://doi.org/10.4049/jimmunol.1600606
Published: 15 April 2017
View article titled, A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma
Click here to open pdf in another window PDF for A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma
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Includes: Supplementary data
Journal Articles

Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation

Hans D. Brightbill, Janet K. Jackman, Eric Suto, Heather Kennedy, Charles Jones, III, Sreedevi Chalasani, Zhonghua Lin, Lucinda Tam, Meron Roose-Girma, Mercedesz Balazs, Cary D. Austin, Wyne P. Lee, Lawren C. Wu
Journal: The Journal of Immunology
J Immunol (2015) 195 (3): 953–964.
DOI: https://doi.org/10.4049/jimmunol.1401514
Published: 01 August 2015
View article titled, Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation
Click here to open pdf in another window PDF for Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation
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Includes: Supplementary data
Journal Articles

Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts

Sanjay Chandriani, Daryle J. DePianto, Elsa N. N’Diaye, Alexander R. Abbas, Janet Jackman, Jack Bevers, III, Vladimir Ramirez-Carrozzi, Rajita Pappu, Steven E. Kauder, Karen Toy, Connie Ha, Zora Modrusan, Lawren C. Wu, Harold R. Collard, Paul J. Wolters, Jackson G. Egen, Joseph R. Arron
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 111–119.
DOI: https://doi.org/10.4049/jimmunol.1301761
Published: 01 July 2014
View article titled, Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts
Click here to open pdf in another window PDF for Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts
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Includes: Supplementary data
Journal Articles

A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

Sue J. Sohn, Kathy Barrett, Anne Van Abbema, Christine Chang, Pawan Bir Kohli, Hidenobu Kanda, Janice Smith, Yingjie Lai, Aihe Zhou, Birong Zhang, Wenqian Yang, Karen Williams, Calum Macleod, Christopher A. Hurley, Janusz J. Kulagowski, Nicholas Lewin-Koh, Hart S. Dengler, Adam R. Johnson, Nico Ghilardi, Mark Zak, Jun Liang, Wade S. Blair, Steven Magnuson, Lawren C. Wu
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2205–2216.
DOI: https://doi.org/10.4049/jimmunol.1202859
Published: 01 September 2013
View article titled, A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
Click here to open pdf in another window PDF for A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
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Includes: Supplementary data
Journal Articles

Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways

David F. Choy, Barmak Modrek, Alexander R. Abbas, Sarah Kummerfeld, Hilary F. Clark, Lawren C. Wu, Grazyna Fedorowicz, Zora Modrusan, John V. Fahy, Prescott G. Woodruff, Joseph R. Arron
Journal: The Journal of Immunology
J Immunol (2011) 186 (3): 1861–1869.
DOI: https://doi.org/10.4049/jimmunol.1002568
Published: 01 February 2011
View article titled, Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways
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Includes: Supplementary data
Journal Articles

Reduction of serum IgE by depletion of the IgE B cell lineage - a novel approach for the treatment of allergic diseases (140.7)

Lawren C Wu, Hans D Brightbill, Surinder Jeet, Zhonghua Lin, Donghong Yan, Meijuan Zhou, Martha Tan, Allen Nguyen, Sherry Yeh, Donnie Delarosa, Steven R Leong, Terence Wong, Yvonne Chen, Janet Jackman, Mark S Dennis, Anan Chuntharapai, Laura DeForge, Y Gloria Meng, Min Xu, Wyne P Lee, Canio J Refino, Mercedesz Balazs
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 140.7.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.140.7
Published: 01 April 2009
View article titled, Reduction of serum IgE by depletion of the IgE B cell lineage - a novel approach for the treatment of allergic diseases (140.7)
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