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Lawrence P. Kane
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Journal Articles

TIM-3+ T regulatory cells alter the lymphoid compartment in cold and Hot solid tumor Model.

Hridesh Banerjee, Hector M Nieves-Rosado, Benjamin Murter, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 180.05.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.180.05
Published: 01 May 2022
View article titled, TIM-3<sup>+</sup> T regulatory cells alter the lymphoid compartment in cold and Hot solid tumor Model.
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Journal Articles

Tim-3 deletion on Treg increases virus-specific T cell response and reduces viral burden in chronic LCMV infection

Hector M Nieves-Rosado, Hridesh Banerjee, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 110.13.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.110.13
Published: 01 May 2022
View article titled, Tim-3 deletion on Treg increases virus-specific T cell response and reduces viral burden in chronic LCMV infection
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Journal Articles

PIK3IP1/TrIP Immune Regulation on CD8+ T Cells Restricts Anti-Tumor Immunity

Benjamin M Murter, Hridesh Banerjee, Andrea Szymczak-Workman, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 121.11.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.121.11
Published: 01 May 2022
View article titled, PIK3IP1/TrIP Immune Regulation on CD8<sup>+</sup> T Cells Restricts Anti-Tumor Immunity
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Journal Articles

Interferon Gamma Induction of TH1-like Tregs Controls Anti-viral Responses

Angela Marie Gocher, Jian Cui, Andrea Szymczak-Workman, Kate Vignali, Julianna N Latini, Gwen P Pieklo, Lyndsay Avery, Ellyse L Cipolla, Brydie R Huckestein, Lee Hedden, Marlies Meisel, John F Alcorn, Lawrence P Kane, Creg J. Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 53.23.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.53.23
Published: 01 May 2022
View article titled, Interferon Gamma Induction of T<sub>H</sub>1-like T<sub>regs</sub> Controls Anti-viral Responses
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Journal Articles

Mechanism of Tim-3 regulation of CD8+ T cell function

Priyanka Manandhar, Emily Elizabeth Landy, Benjamin Murter, Hridesh Banerjee, Andrea Workman, Isabella Bosco, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 55.04.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.55.04
Published: 01 May 2022
View article titled, Mechanism of Tim-3 regulation of CD8+ T cell function
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Journal Articles

Expression of Tim-3 drives Treg to an effector-like state with enhanced suppressive activity and altered response to tumor

Hridesh Banerjee, Hector Nieves-Rosado, Benjamin Matthew Murter, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 57.19.
DOI: https://doi.org/10.4049/jimmunol.206.Supp.57.19
Published: 01 May 2021
View article titled, Expression of Tim-3 drives Treg to an effector-like state with enhanced suppressive activity and altered response to tumor
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Elucidating the roles of PIK3IP1/TrIP in PI3-kinase regulation, T cell differentiation and T cell function in vivo

Benjamin M Murter, hridesh banerjee, Andrea Szymczak-Workman, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 57.24.
DOI: https://doi.org/10.4049/jimmunol.206.Supp.57.24
Published: 01 May 2021
View article titled, Elucidating the roles of PIK3IP1/TrIP in PI3-kinase regulation, T cell differentiation and T cell function in vivo
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Journal Articles

Enhanced suppressive phenotype of Tim-3+ Treg during chronic infection

Hector M Nieves-Rosado, Hridesh Banerjee, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 96.06.
DOI: https://doi.org/10.4049/jimmunol.206.Supp.96.06
Published: 01 May 2021
View article titled, Enhanced suppressive phenotype of Tim-3+ Treg during chronic infection
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Journal Articles

PIK3IP1 Promotes Extrafollicular Class Switching in T-Dependent Immune Responses

Kristina Ottens, Jalyn Schneider, Lawrence P. Kane, Anne B. Satterthwaite
Journal: The Journal of Immunology
J Immunol (2020) 205 (8): 2100–2108.
DOI: https://doi.org/10.4049/jimmunol.2000584
Published: 15 October 2020
View article titled, PIK3IP1 Promotes Extrafollicular Class Switching in T-Dependent Immune Responses
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Includes: Supplementary data
Journal Articles

Polyubiquitin-dependent recruitment of NEMO/IKKγ into T cell receptor signaling microclusters is controlled by IKKβ kinase activity

Nicholas Robert Koylass, Elizabeth DeRiso, Andrea L Szymczak-Workman, Angela Montecalvo, Joanne M. Murphy, Maria-Cristina Seminario, Stephen C Bunnell, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 80.1.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.80.1
Published: 01 May 2020
View article titled, Polyubiquitin-dependent recruitment of NEMO/IKKγ into T cell receptor signaling microclusters is controlled by IKKβ kinase activity
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Journal Articles

The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function

Gerard Hernandez-Mir, Itay Raphael, Shankar Revu, Catherine H. Poholek, Lyndsay Avery, William F. Hawse, Lawrence P. Kane, Mandy J. McGeachy
Journal: The Journal of Immunology
J Immunol (2019) 203 (3): 665–675.
DOI: https://doi.org/10.4049/jimmunol.1800363
Published: 01 August 2019
View article titled, The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function
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Includes: Supplementary data
Journal Articles

Recruitment of NEMO/IKKγ to TCR microclusters during T cell activation

Nicholas Robert Koylass, Elizabeth A. DeRiso, Andrea L. Szymczak-Workman, Angela Montecalvo, Joanne M. Murphy, Maria Cristina Seminario, Lawrence P. Kane, Stephen C. Bunnell
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 184.1.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.184.1
Published: 01 May 2019
View article titled, Recruitment of NEMO/IKKγ to TCR microclusters during T cell activation
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Journal Articles

Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions

Binh Phong, Lyndsay Avery, Ashley V. Menk, Greg M. Delgoffe, Lawrence P. Kane
Journal: The Journal of Immunology
J Immunol (2017) 198 (2): 640–644.
DOI: https://doi.org/10.4049/jimmunol.1601150
Published: 15 January 2017
View article titled, Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions
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Includes: Supplementary data
Journal Articles

Defining the role of Tim-3 in T cells

Lyndsay Avery, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 55.16.
DOI: https://doi.org/10.4049/jimmunol.196.Supp.55.16
Published: 01 May 2016
View article titled, Defining the role of Tim-3 in T cells
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Journal Articles

PIK3IP1- A novel negative regulator of PI3K

Uzodinma N Uche, Lawrence P Kane
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 57.9.
DOI: https://doi.org/10.4049/jimmunol.196.Supp.57.9
Published: 01 May 2016
View article titled, PIK3IP1- A novel negative regulator of PI3K
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Journal Articles

Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions

William F. Hawse, Robert P. Sheehan, Natasa Miskov-Zivanov, Ashley V. Menk, Lawrence P. Kane, James R. Faeder, Penelope A. Morel
Journal: The Journal of Immunology
J Immunol (2015) 194 (10): 4615–4619.
DOI: https://doi.org/10.4049/jimmunol.1402554
Published: 15 May 2015
View article titled, Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4<sup>+</sup> T Cell Fate Decisions
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Includes: Supplementary data
Journal Articles

Antigen Receptor Kinase Two-Step

In Special Collection:
Pillars of Immunology
Lawrence P. Kane
Journal: The Journal of Immunology
J Immunol (2014) 193 (9): 4277–4278.
DOI: https://doi.org/10.4049/jimmunol.1402287
Published: 01 November 2014
View article titled, Antigen Receptor Kinase Two-Step
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Journal Articles

Complement Component C5a Permits the Coexistence of Pathogenic Th17 Cells and Type I IFN in Lupus

Sudesh Pawaria, Kritika Ramani, Kelly Maers, Youhua Liu, Lawrence P. Kane, Marc C. Levesque, Partha S. Biswas
Journal: The Journal of Immunology
J Immunol (2014) 193 (7): 3288–3295.
DOI: https://doi.org/10.4049/jimmunol.1401322
Published: 01 October 2014
View article titled, Complement Component C5a Permits the Coexistence of Pathogenic Th17 Cells and Type I IFN in Lupus
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Includes: Supplementary data
Journal Articles

Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion

In Special Collection:
Brief Reviews
Robert L. Ferris, Binfeng Lu, Lawrence P. Kane
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 1525–1530.
DOI: https://doi.org/10.4049/jimmunol.1400557
Published: 15 August 2014
View article titled, Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion
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Journal Articles

Correction: T Cell Ig and Mucin Domain Proteins and Immunity

Lawrence P. Kane
Journal: The Journal of Immunology
J Immunol (2012) 189 (9): 4695.
DOI: https://doi.org/10.4049/jimmunol.1290065
Published: 01 November 2012
View article titled, Correction: T Cell Ig and Mucin Domain Proteins and Immunity
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