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Journal Articles

The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy

Nuria Villalba, Adrian M. Sackheim, Michael A. Lawson, Laurel Haines, Yen-Lin Chen, Swapnil K. Sonkusare, Yong-Tao Ma, Jianing Li, Devdoot Majumdar, Beth A. Bouchard, Jonathan E. Boyson, Matthew E. Poynter, Mark T. Nelson, Kalev Freeman
Journal: The Journal of Immunology
J Immunol (2023) 211 (4): 648–657.
https://doi.org/10.4049/jimmunol.2200703
Published: 05 July 2023
View article titled, The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy
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Includes: Multimedia, Supplementary data
Journal Articles

Rebalancing TGFβ1/BMP Signaling Epigenetically Reprograms Fully Exhausted Human CD8 T Cells into a Functional State

Hazem E. Ghoneim, Abbey A Saadey, Amir Yousif, Nicole Osborne, Yu-Lin Chen, Brooke Laster, Ahmed Zayed, Parker Bauman
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 121.10.
https://doi.org/10.4049/jimmunol.208.Supp.121.10
Published: 01 May 2022
View article titled, Rebalancing TGFβ1/BMP Signaling Epigenetically Reprograms Fully Exhausted Human CD8 T Cells into a Functional State
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Journal Articles

Airway Epithelial cGAS Is Critical for Induction of Experimental Allergic Airway Inflammation

Yinling Han, Lin Chen, Huiwen Liu, Zhangchu Jin, Yinfang Wu, Yanping Wu, Wen Li, Songmin Ying, Zhihua Chen, Huahao Shen, Fugui Yan
Journal: The Journal of Immunology
J Immunol (2020) 204 (6): 1437–1447.
https://doi.org/10.4049/jimmunol.1900869
Published: 15 March 2020
View article titled, Airway Epithelial cGAS Is Critical for Induction of Experimental Allergic Airway Inflammation
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Includes: Supplementary data
Journal Articles

Galectin-3 promotes non-canonical inflammasome activation through binding to glycans on LPS intracellularly

Tzu-Han Lo, Hung-Lin Chen, Huan-Yuan Chen, Fu-Tong Liu
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 183.1.
https://doi.org/10.4049/jimmunol.202.Supp.183.1
Published: 01 May 2019
View article titled, Galectin-3 promotes non-canonical inflammasome activation through binding to glycans on LPS intracellularly
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Journal Articles

Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice

Zhiping Ren, Lin Chen, Yimeng Wang, Xinbing Wei, Shenglan Zeng, Yi Zheng, Chengjiang Gao, Huiqing Liu
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 747–759.
https://doi.org/10.4049/jimmunol.1800637
Published: 01 February 2019
View article titled, Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice
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Includes: Supplementary data
Journal Articles

Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells

Yue Li, Xiaoqun Guan, Weiren Liu, Hung-Lin Chen, Jamie Truscott, Sonay Beyatli, Ahmed Metwali, George J. Weiner, Nicholas Zavazava, Richard S. Blumberg, Joseph F. Urban, Jr., Bruce R. Blazar, David E. Elliott, M. Nedim Ince
Journal: The Journal of Immunology
J Immunol (2018) 201 (10): 2910–2922.
https://doi.org/10.4049/jimmunol.1700638
Published: 15 November 2018
View article titled, Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells
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Includes: Supplementary data
Journal Articles

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells

Yue Li, Weiren Liu, Xiaqun Guan, Jamie Truscott, John W. Creemers, Hung-Lin Chen, Marko Pesu, Rami G. El Abiad, Bahri Karacay, Joseph F. Urban, Jr., David E. Elliott, Mark H. Kaplan, Bruce R. Blazar, M. Nedim Ince
Journal: The Journal of Immunology
J Immunol (2018) 201 (9): 2612–2623.
https://doi.org/10.4049/jimmunol.1700808
Published: 01 November 2018
View article titled, STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells
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Includes: Supplementary data
Journal Articles

Predictive Analysis of Mechanistic Triggers and Mitigation Strategies for Pathological Scarring in Skin Wounds

Sridevi Nagaraja, Lin Chen, Jian Zhou, Yan Zhao, David Fine, Luisa A. DiPietro, Jaques Reifman, Alexander Y. Mitrophanov
Journal: The Journal of Immunology
J Immunol (2017) 198 (2): 832–841.
https://doi.org/10.4049/jimmunol.1601273
Published: 15 January 2017
View article titled, Predictive Analysis of Mechanistic Triggers and Mitigation Strategies for Pathological Scarring in Skin Wounds
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Includes: Supplementary data
Journal Articles

Intestinal Helminths Regulate Lethal Acute Graft-versus-Host Disease and Preserve the Graft-versus-Tumor Effect in Mice

Yue Li, Hung-Lin Chen, Nadine Bannick, Michael Henry, Adrian N. Holm, Ahmed Metwali, Joseph F. Urban, Jr., Paul B. Rothman, George J. Weiner, Bruce R. Blazar, David E. Elliott, M. Nedim Ince
Journal: The Journal of Immunology
J Immunol (2015) 194 (3): 1011–1020.
https://doi.org/10.4049/jimmunol.1303099
Published: 01 February 2015
View article titled, Intestinal Helminths Regulate Lethal Acute Graft-versus-Host Disease and Preserve the Graft-versus-Tumor Effect in Mice
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Includes: Supplementary data
Journal Articles

Artesunate versus Chloroquine Infection–Treatment–Vaccination Defines Stage-Specific Immune Responses Associated with Prolonged Sterile Protection against Both Pre-erythrocytic and Erythrocytic Plasmodium yoelii Infection

Xiaohong Peng, Gladys J. Keitany, Marissa Vignali, Lin Chen, Claire Gibson, Kimberly Choi, Fusheng Huang, Ruobing Wang
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1268–1277.
https://doi.org/10.4049/jimmunol.1400296
Published: 01 August 2014
View article titled, Artesunate versus Chloroquine Infection–Treatment–Vaccination Defines Stage-Specific Immune Responses Associated with Prolonged Sterile Protection against Both Pre-erythrocytic and Erythrocytic <em>Plasmodium yoelii</em> Infection
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Includes: Supplementary data
Journal Articles

Associating long-lived liver CD49b+CD8b+ T cells with long-lasting immunity against malaria (P4481)

Ihn Jang, Lin Chen, Xiaohong Peng, Kimberly Choi, Claire Gibson, Ruobing Wang
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 179.3.
https://doi.org/10.4049/jimmunol.190.Supp.179.3
Published: 01 May 2013
View article titled, Associating long-lived liver CD49b+CD8b+ T cells with long-lasting immunity against malaria (P4481)
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Journal Articles

Inflammatory cytokines in the pathogenesis of autoimmune type 1 diabetes (123.21)

Sheela Ramanathan, Diwakar Bobbala, Xi Lin Chen, Marian Mayhue, Chantal Leblanc, Toshiyuki Tanaka, Yi-Guang Chen, Subburaj Ilangumaran
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 123.21.
https://doi.org/10.4049/jimmunol.188.Supp.123.21
Published: 01 May 2012
View article titled, Inflammatory cytokines in the pathogenesis of autoimmune type 1 diabetes (123.21)
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Journal Articles

TOLL-LIKE RECEPTOR 4 PLAYS AN ESSENTIAL ROLE IN EARLY SKIN WOUND HEALING (180.1)

Lin Chen, Shujuan Guo, Matthew Ranzer, Luisa DiPietro
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 180.1.
https://doi.org/10.4049/jimmunol.188.Supp.180.1
Published: 01 May 2012
View article titled, TOLL-LIKE RECEPTOR 4 PLAYS AN ESSENTIAL ROLE IN EARLY SKIN WOUND HEALING (180.1)
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Journal Articles

Exposure to IL-15 and IL-21 Enables Autoreactive CD8 T Cells To Respond to Weak Antigens and Cause Disease in a Mouse Model of Autoimmune Diabetes

Sheela Ramanathan, Stephanie Dubois, Xi-Lin Chen, Chantal Leblanc, Pamela S. Ohashi, Subburaj Ilangumaran
Journal: The Journal of Immunology
J Immunol (2011) 186 (9): 5131–5141.
https://doi.org/10.4049/jimmunol.1001221
Published: 01 May 2011
View article titled, Exposure to IL-15 and IL-21 Enables Autoreactive CD8 T Cells To Respond to Weak Antigens and Cause Disease in a Mouse Model of Autoimmune Diabetes
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Journal Articles

Cytokine priming enables triggering of autoreactive CD8 T lymphocytes by low affinity TCR ligands (83.7)

Subburaj Ilangumaran, Stephanie Dubois, Xi Lin Chen, Chantal Leblanc, Pamela Ohashi, Sheela Ramanathan
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 83.7.
https://doi.org/10.4049/jimmunol.184.Supp.83.7
Published: 01 April 2010
View article titled, Cytokine priming enables triggering of autoreactive CD8 T lymphocytes by low affinity TCR ligands (83.7)
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Journal Articles

Lipopolysaccharide-Induced Heme Oxygenase-1 Expression in Human Monocytic Cells Is Mediated via Nrf2 and Protein Kinase C

Stuart A. Rushworth, Xi-Lin Chen, Nigel Mackman, Richard M. Ogborne, Maria A. O’Connell
Journal: The Journal of Immunology
J Immunol (2005) 175 (7): 4408–4415.
https://doi.org/10.4049/jimmunol.175.7.4408
Published: 01 October 2005
View article titled, Lipopolysaccharide-Induced Heme Oxygenase-1 Expression in Human Monocytic Cells Is Mediated via Nrf2 and Protein Kinase C
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