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Linda V. Sinclair
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Journal Articles

Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions

Eimear K. Ryan, Christy Clutter, Conor De Barra, Benjamin J. Jenkins, Simon O’Shaughnessy, Odhrán K. Ryan, Chloe McKenna, Helen M. Heneghan, Fiona Walsh, David K. Finlay, Linda V. Sinclair, Nicholas Jones, Daniel T. Leung, Donal O’Shea, Andrew E. Hogan
Journal: The Journal of Immunology
J Immunol (2024) 212 (11): 1706–1713.
https://doi.org/10.4049/jimmunol.2300649
Published: 15 April 2024
View articletitled, Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions
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Includes: Supplementary data
Journal Articles

Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression

Ana Villegas-Mendez, Garima Khandelwal, Lucy M. McGowan, Rebecca S. Dookie, Michael J. Haley, Charlotte George, David Sims, Graham M. Lord, Linda V. Sinclair, Richard G. Jenner, Kevin N. Couper
Journal: The Journal of Immunology
J Immunol (2020) 205 (6): 1608–1619.
https://doi.org/10.4049/jimmunol.2000450
Published: 15 September 2020
View articletitled, Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression
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Includes: Supplementary data
Journal Articles

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses

Aisling O’Brien, Roisin M. Loftus, Marta M. Pisarska, Laura M. Tobin, Ronan Bergin, Nicole A. W. Wood, Cathriona Foley, Arimin Mat, Frances C. Tinley, Ciaran Bannan, Gary Sommerville, Natacha Veerapen, Gurdyal S. Besra, Linda V. Sinclair, Paul N. Moynagh, Lydia Lynch, David K. Finlay, Donal O’Shea, Andrew E. Hogan
Journal: The Journal of Immunology
J Immunol (2019) 202 (12): 3404–3411.
https://doi.org/10.4049/jimmunol.1801600
Published: 15 June 2019
View articletitled, Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses
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Add to Citation Manager for Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses
Includes: Supplementary data
Journal Articles

Temporal Differences in the Dependency on Phosphoinositide-Dependent Kinase 1 Distinguish the Development of Invariant Vα14 NKT Cells and Conventional T Cells

David K. Finlay, April P. Kelly, Rosemary Clarke, Linda V. Sinclair, Maria Deak, Dario R. Alessi, Doreen A. Cantrell
Journal: The Journal of Immunology
J Immunol (2010) 185 (10): 5973–5982.
https://doi.org/10.4049/jimmunol.1000827
Published: 15 November 2010
View articletitled, Temporal Differences in the Dependency on Phosphoinositide-Dependent Kinase 1 Distinguish the Development of Invariant Vα14 NKT Cells and Conventional T Cells
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Add to Citation Manager for Temporal Differences in the Dependency on Phosphoinositide-Dependent Kinase 1 Distinguish the Development of Invariant Vα14 NKT Cells and Conventional T Cells
Includes: Supplementary data