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Luke A. J. O’Neill
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Journal Articles

4-Octyl Itaconate and Dimethyl Fumarate Induce Secretion of the Anti-Inflammatory Protein Annexin A1 via NRF2

Ciana Diskin, Emily A. Day, Órlaith C. Henry, Juliana E. Toller-Kawahisa, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2023) 211 (6): 1032–1041.
https://doi.org/10.4049/jimmunol.2200848
Published: 14 August 2023
View article titled, 4-Octyl Itaconate and Dimethyl Fumarate Induce Secretion of the Anti-Inflammatory Protein Annexin A1 via NRF2
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Includes: Supplementary data
Journal Articles

The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2

Ciana Diskin, Sarah E. Corcoran, Victoria J. Tyrrell, Anne F. McGettrick, Zbigniew Zaslona, Valerie B. O’Donnell, Derek P. Nolan, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2021) 207 (10): 2551–2560.
https://doi.org/10.4049/jimmunol.2100402
Published: 15 November 2021
View article titled, The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2
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Includes: Supplementary data
Journal Articles

4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages

Ciana Diskin, Alessia Zotta, Sarah E. Corcoran, Victoria J. Tyrrell, Zbigniew Zaslona, Valerie B. O’Donnell, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2021) 207 (10): 2561–2569.
https://doi.org/10.4049/jimmunol.2100488
Published: 15 November 2021
View article titled, 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages
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Includes: Supplementary data
Journal Articles

The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production

Zbigniew Zasłona, Eva M. Pålsson-McDermott, Deepthi Menon, Moritz Haneklaus, Ewelina Flis, Hannah Prendeville, Sarah E. Corcoran, Marc Peters-Golden, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2017) 198 (9): 3558–3564.
https://doi.org/10.4049/jimmunol.1602072
Published: 01 May 2017
View article titled, The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E<sub>2</sub> Production
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Journal Articles

Feeding immunity: The regulation of circadian immune responses by mealtimes

Sarah Sofia Geiger, Javier Traba, Michael N. Sack, Luke A. J. O’Neill, Richard M. Siegel
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 75.21.
https://doi.org/10.4049/jimmunol.198.Supp.75.21
Published: 01 May 2017
View article titled, Feeding immunity: The regulation of circadian immune responses by mealtimes
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Journal Articles

Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication

Laura E. Gleeson, Frederick J. Sheedy, Eva M. Palsson-McDermott, Denise Triglia, Seonadh M. O’Leary, Mary P. O’Sullivan, Luke A. J. O’Neill, Joseph Keane
Journal: The Journal of Immunology
J Immunol (2016) 196 (6): 2444–2449.
https://doi.org/10.4049/jimmunol.1501612
Published: 15 March 2016
View article titled, Cutting Edge: <em>Mycobacterium tuberculosis</em> Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication
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Includes: Supplementary data
Journal Articles

TRIL Is Involved in Cytokine Production in the Brain following Escherichia coli Infection

Paulina Wochal, Vijay A. K. Rathinam, Aisling Dunne, Thaddeus Carlson, Wen Kuang, Katherine J. Seidl, J. Perry Hall, Lih-Ling Lin, Mary Collins, Stefan A. Schattgen, Christopher R. MacKay, Caio T. Fagundes, Susan Carpenter, Katherine A. Fitzgerald, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 1911–1919.
https://doi.org/10.4049/jimmunol.1302392
Published: 15 August 2014
View article titled, TRIL Is Involved in Cytokine Production in the Brain following <em>Escherichia coli</em> Infection
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Includes: Supplementary data
Journal Articles

Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production

Moritz Haneklaus, Motti Gerlic, Mariola Kurowska-Stolarska, Ashleigh-Ann Rainey, Dagmar Pich, Iain B. McInnes, Wolfgang Hammerschmidt, Luke A. J. O’Neill, Seth L. Masters
Journal: The Journal of Immunology
J Immunol (2012) 189 (8): 3795–3799.
https://doi.org/10.4049/jimmunol.1200312
Published: 15 October 2012
View article titled, Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production
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Includes: Supplementary data
Journal Articles

TLR9 Provokes Inflammation in Response to Fetal DNA: Mechanism for Fetal Loss in Preterm Birth and Preeclampsia

Andrea Scharfe-Nugent, Sinéad C. Corr, Susan B. Carpenter, Louise Keogh, Brendan Doyle, Cara Martin, Katherine A. Fitzgerald, Sean Daly, John J. O’Leary, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5706–5712.
https://doi.org/10.4049/jimmunol.1103454
Published: 01 June 2012
View article titled, TLR9 Provokes Inflammation in Response to Fetal DNA: Mechanism for Fetal Loss in Preterm Birth and Preeclampsia
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Journal Articles

TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain

Susan Carpenter, Thaddeus Carlson, Jerome Dellacasagrande, Amaya Garcia, Sharon Gibbons, Paul Hertzog, Anthony Lyons, Lih-Ling Lin, Marina Lynch, Tom Monie, Caroline Murphy, Katherine J. Seidl, Christine Wells, Aisling Dunne, Luke A. J. O'Neill
Journal: The Journal of Immunology
J Immunol (2009) 183 (6): 3989–3995.
https://doi.org/10.4049/jimmunol.0901518
Published: 15 September 2009
View article titled, TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain
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Journal Articles

MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3

Elaine F. Kenny, Suzanne Talbot, Mei Gong, Douglas T. Golenbock, Clare E. Bryant, Luke A. J. O'Neill
Journal: The Journal of Immunology
J Immunol (2009) 183 (6): 3642–3651.
https://doi.org/10.4049/jimmunol.0901140
Published: 15 September 2009
View article titled, MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3
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Journal Articles

Vitamin C Inhibits NF-κB Activation by TNF Via the Activation of p38 Mitogen-Activated Protein Kinase

Andrew G. Bowie, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2000) 165 (12): 7180–7188.
https://doi.org/10.4049/jimmunol.165.12.7180
Published: 15 December 2000
View article titled, Vitamin C Inhibits NF-κB Activation by TNF Via the Activation of p38 Mitogen-Activated Protein Kinase
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Journal Articles

Ras, Protein Kinase Cζ, and IκB Kinases 1 and 2 Are Downstream Effectors of CD44 During the Activation of NF-κB by Hyaluronic Acid Fragments in T-24 Carcinoma Cells

Katherine A. Fitzgerald, Andrew G. Bowie, Barbara Sheehy Skeffington, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (2000) 164 (4): 2053–2063.
https://doi.org/10.4049/jimmunol.164.4.2053
Published: 15 February 2000
View article titled, Ras, Protein Kinase Cζ, and IκB Kinases 1 and 2 Are Downstream Effectors of CD44 During the Activation of NF-κB by Hyaluronic Acid Fragments in T-24 Carcinoma Cells
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Journal Articles

Characterization of CD44 Induction by IL-1: A Critical Role for Egr-1

Katherine A. Fitzgerald, Luke A. J. O’Neill
Journal: The Journal of Immunology
J Immunol (1999) 162 (8): 4920–4927.
https://doi.org/10.4049/jimmunol.162.8.4920
Published: 15 April 1999
View article titled, Characterization of CD44 Induction by IL-1: A Critical Role for Egr-1
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